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JARID2 (NM_004973) Human Untagged Clone
CAT＃: SC309940
JARID2 (untagged)-Human jumonji, AT rich interactive domain 2 (JARID2)
CNY 10,450.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | JMJ |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC309940 representing NM_004973.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGAGCAAGGAAAGACCCAAGAGGAATATCATTCAGAAGAAATACGATGACAGTGATGGGATTCCGTGG TCAGAAGAACGGGTGGTACGTAAAGTCCTTTATTTGTCTCTGAAGGAGTTCAAGAATTCCCAGAAGAGG CAGCATGCGGAAGGCATTGCTGGGAGCCTGAAAACTGTGAATGGGCTCCTTGGTAATGACCAGTCTAAG GGATTAGGACCAGCATCAGAACAGTCAGAGAATGAAAAGGACGATGCATCCCAAGTGTCCTCCACTAGC AACGATGTTAGTTCTTCAGATTTTGAAGAAGGGCCGTCGAGGAAAAGGCCCAGGCTGCAAGCACAAAGG AAGTTTGCTCAGTCTCAGCCGAATAGTCCCAGCACAACTCCAGTAAAGATAGTGGAGCCATTGCTACCC CCTCCAGCTACTCAGATATCAGACCTCTCTAAAAGGAAGCCTAAGACAGAAGATTTTCTTACCTTTCTC TGCCTTCGAGGTTCTCCTGCGCTGCCCAACAGCATGGTGTATTTTGGAAGCTCTCAGGATGAGGAGGAA GTCGAGGAGGAAGATGATGAGACAGAAGACGTCAAAACAGCCACCAACAATGCTTCATCTTCATGCCAG TCGACCCCCAGGAAAGGAAAAACCCACAAACATGTTCACAACGGGCATGTTTTCAATGGTTCCAGCAGG TCAACACGGGAGAAGGAACCTGTTCAAAAACACAAAAGCAAAGAGGCCACTCCCGCAAAGGAGAAGCAC AGCGATCACCGGGCTGACAGCCGCCGGGAGCAGGCTTCAGCTAACCACCCCGCAGCGGCCCCCTCCACG GGTTCCTCGGCCAAGGGGCTTGCTGCCACCCATCACCACCCCCCTCTGCATCGGTCGGCTCAGGACTTA CGGAAACAGGTTTCTAAGGTAAACGGAGTCACTCGAATGTCATCTCTGGGTGCAGGTGTAACCAGTGCC AAAAAGATGCGCGAGGTCAGACCTTCACCATCCAAAACTGTGAAGTACACTGCCACGGTGACGAAGGGG GCTGTCACATACACCAAAGCCAAGAGAGAACTGGTCAAGGACACCAAACCCAATCACCACAAGCCCAGT TCCGCTGTCAACCACACAATCTCAGGGAAAACTGAAAGTAGCAATGCAAAAACCCGCAAACAGGTGCTA TCCCTCGGGGGGGCGTCCAAGTCCACTGGGCCCGCCGTCAATGGCCTCAAGGTCAGTGGCAGGTTGAAC CCAAAGTCATGCACTAAGGAGGTGGGGGGGCGGCAGCTGCGGGAGGGCCTGCAGCTGCGGGAGGGGCTG CGGAACTCCAAGAGGAGACTGGAAGAGGCACACCAGGCGGAGAAGCCGCAGTCGCCCCCCAAGAAGATG AAAGGGGCGGCTGGCCCCGCCGAAGGCCCTGGCAAGAAGGCCCCGGCCGAGAGAGGTCTGCTGAACGGA CACGTGAAGAAGGAAGTGCCGGAGCGCAGTCTGGAGAGGAATCGGCCGAAGCGGGCCACGGCCGGGAAG AGCACGCCAGGCAGACAAGCACATGGCAAGGCGGACAGCGCCTCCTGTGAAAATCGTTCTACCTCGCAA CCGGAGTCCGTGCACAAGCCGCAGGACTCGGGCAAGGCCGAGAAGGGCGGCGGCAAGGCCGGGTGGGCG GCCATGGACGAGATCCCCGTCCTCAGGCCCTCCGCCAAGGAGTTCCACGATCCGCTCATCTACATCGAG TCGGTCCGCGCTCAGGTGGAGAAGTTCGGGATGTGCAGGGTGATCCCCCCTCCGGACTGGCGGCCCGAG TGCAAGCTCAACGATGAGATGCGGTTTGTCACGCAGATTCAGCACATCCACAAGCTGGGCCGGCGCTGG GGCCCCAACGTGCAGCGGCTGGCCTGCATCAAGAAGCACCTCAAATCTCAGGGCATCACCATGGACGAG CTCCCGCTCATAGGGGGCTGTGAGCTCGACCTGGCCTGCTTTTTCCGGCTGATTAATGAGATGGGCGGC ATGCAGCAAGTGACTGACCTCAAAAAATGGAACAAACTAGCAGACATGCTGCGCATCCCCAGAACTGCC CAGGACCGGCTGGCCAAGCTGCAGGAGGCCTACTGCCAGTACCTACTCTCCTACGACTCCCTGTCCCCA GAGGAGCACCGGCGGCTGGAGAAGGAGGTGCTGATGGAGAAGGAGATCCTGGAGAAGCGCAAGGGGCCG CTGGAAGGCCACACAGAGAACGACCACCACAAGTTCCACCCTCTGCCCCGCTTCGAGCCCAAGAATGGG CTCATCCACGGCGTGGCCCCCAGGAACGGCTTCCGCAGCAAGCTCAAGGAGGTGGGCCAGGCCCAGTTG AAGACTGGCCGGCGGCGACTCTTCGCTCAGGAAAAAGAAGTGGTCAAGGAAGAGGAGGAGGACAAAGGC GTCCTCAATGACTTCCACAAGTGCATCTATAAGGGAAGGTCTGTTTCTCTAACAACTTTTTATCGAACA GCGAGGAATATCATGAGCATGTGTTTCAGCAAGGAGCCTGCCCCAGCCGAAATCGAGCAAGAGTACTGG AGGCTAGTGGAAGAGAAGGACTGCCACGTGGCAGTGCACTGCGGCAAGGTGGACACCAACACTCACGGC AGTGGATTCCCAGTAGGAAAATCAGAACCCTTTTCGAGGCATGGATGGAACCTCACCGTCCTCCCCAAT AACACAGGGTCCATCCTGCGTCACCTCGGTGCTGTGCCTGGAGTGACTATTCCCTGGCTAAATATTGGC ATGGTCTTTTCTACCTCATGCTGGTCTCGAGACCAAAATCACCTTCCATACATTGACTACTTACACACT GGTGCTGACTGCATTTGGTATTGCATTCCTGCTGAGGAGGAGAACAAGCTGGAAGATGTGGTCCACACC CTGCTGCAAGCCAATGGCACCCCAGGGCTGCAGATGCTGGAAAGCAACGTCATGATCTCCCCGGAGGTG CTGTGCAAAGAGGGGATCAAGGTGCACAGGACCGTGCAGCAGAGTGGCCAGTTTGTCGTCTGCTTCCCG GGATCCTTTGTGTCCAAAGTGTGCTGTGGGTACAGCGTGTCTGAAACCGTGCACTTTGCTACCACCCAG TGGACAAGTATGGGCTTTGAGACCGCCAAGGAAATGAAGCGTCGCCATATAGCTAAGCCATTCTCCATG GAGAAGTTACTCTACCAGATTGCACAAGCAGAAGCAAAAAAAGAAAACGGTCCCACTCTCAGTACCATC TCAGCCCTCCTGGATGAGCTCAGGGATACAGAGCTGCGGCAGCGCAGGCAGCTGTTCGAGGCTGGCCTC CACTCCTCCGCACGCTATGGCAGCCACGATGGCAGCAGCACGGTGGCGGACGGGAAGAAAAAGCCTCGA AAGTGGCTGCAGTTGGAGACGTCAGAGAGGAGGTGTCAGATCTGCCAGCACCTGTGCTACCTGTCCATG GTGGTACAAGAGAACGAAAACGTCGTGTTCTGTCTGGAGTGTGCTCTGCGCCACGTGGAGAAACAGAAG TCCTGCCGAGGGCTGAAGTTGATGTACCGCTACGATGAGGAACAGATTATCAGTCTGGTCAATCAGATC TGCGGCAAAGTGTCTGGTAAAAACGGCAGCATTGAGAACTGTCTCAGTAAACCCACACCAAAAAGAGGT CCCCGCAAGAGAGCGACAGTGGACGTGCCCCCCTCCCGTCTGTCAGCCTCCAGTTCATCCAAAAGTGCT TCGAGCTCATCATGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_004973 |
| Insert Size | 3741 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004973.3 |
| RefSeq Size | 6112 bp |
| RefSeq ORF | 3741 bp |
| Locus ID | 3720 |
| UniProt ID | Q92833 |
| Domains | ARID, JmjC, JmjN, zf-C5HC2 |
| Protein Families | Transcription Factors |
| MW | 138.7 kDa |
| Gene Summary | This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Jarid2 enhances the progression of bladder cancer through regulating PTEN/AKT signaling
,Wang, X;Lyu, J;Ji, A;Zhang, Q;Liao, G;,
Life Sci.
,PubMed ID 31125562
[JARID2]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207885 | JARID2 (Myc-DDK-tagged)-Human jumonji, AT rich interactive domain 2 (JARID2) |
CNY 8,680.00 |
|
| RC207885L1 | Lenti-ORF clone of JARID2 (Myc-DDK-tagged)-Human jumonji, AT rich interactive domain 2 (JARID2) |
CNY 11,080.00 |
|
| RC207885L2 | Lenti-ORF clone of JARID2 (mGFP-tagged)-Human jumonji, AT rich interactive domain 2 (JARID2) |
CNY 11,500.00 |
|
| RC207885L3 | Lenti-ORF clone of JARID2 (Myc-DDK-tagged)-Human jumonji, AT rich interactive domain 2 (JARID2) |
CNY 11,500.00 |
|
| RC207885L4 | Lenti-ORF clone of JARID2 (mGFP-tagged)-Human jumonji, AT rich interactive domain 2 (JARID2) |
CNY 11,080.00 |
|
| RG207885 | JARID2 (tGFP-tagged) - Human jumonji, AT rich interactive domain 2 (JARID2) |
CNY 10,280.00 |
