United States
Germany
Japan
United Kingdom
China
KALRN (NM_007064) Human Untagged Clone
CAT＃: SC309929
KALRN (untagged)-Human kalirin, RhoGEF kinase (KALRN), transcript variant 3
CNY 24,890.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARHGEF24; CHD5; CHDS5; DUET; DUO; HAPIP; TRAD |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC309929 representing NM_007064.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGAAGGGCGGCGACAGGGCTTACACCCGAGGTCCCTCTTTGGGGTGGCTCTTTGCTAAGTGCTGCTGT TGCTTCCCGTGTAGAGATGCATACTCTCATTCCTCAAGCGAGAATGGAGGCAAGTCCGAGTCCGTGGCC AACCTGCAGGCCCAGCCCTCCCTGAACTCCATCCACAGTTCCCCGGGTCCCAAGCGCTCCACCAACACT CTTAAGAAGTGGCTGACGAGTCCTGTGCGTCGGCTTAACAGCGGGAAGGCAGATGGAAACATCAAAAAG CAGAAGAAAGTTCGCGATGGTCGGAAGAGCTTTGACCTGGGATCTCCCAAGCCTGGGGATGAAACAACC CCTCAGGGAGACAGCGCTGATGAGAAGAGCAAGAAAGGTTGGGGTGAAGATGAGCCGGATGAAGAGTCA CACACACCCCTCCCACCACCTATGAAGATTTTTGACAACGACCCTACACAGGATGAAATGTCCTCCTCT TTGCTAGCAGCCCGGCAGGCTTCCACTGAAGTACCTACTGCTGCAGACCTTGTCAATGCAATAGAAAAG TTGGTCAAAAACAAGCTGAGTCTAGAAGGAAGCTCATACCGGGGGAGCTTGAAAGACCCTGCAGGCTGC CTGAATGAGGGGATGGCCCCACCCACACCTCCTAAAAACCCAGAAGAAGAACAGAAAGCCAAGGCCCTG AGAGGCAGGATGTTTGTCCTGAATGAGCTGGTACAGACAGAGAAAGACTATGTCAAGGATCTGGGCATT GTGGTGGAGGGCTTCATGAAGAGAATAGAAGAAAAGGGTGTCCCTGAGGATATGCGAGGAAAGGACAAA ATCGTGTTTGGAAATATTCATCAGATTTATGACTGGCATAAGGATTTTTTCCTGGCGGAACTGGAAAAG TGTATCCAGGAGCAAGACAGATTGGCACAGCTCTTTATTAAGCACGAGCGGAAGCTGCACATCTACGTG TGGTATTGTCAGAATAAGCCGCGCTCAGAGTACATCGTTGCTGAGTATGACGCCTACTTTGAGGAGGTA AAACAGGAGATAAATCAGAGGCTGACACTGAGTGACTTCCTCATCAAGCCCATTCAGAGAATAACAAAA TACCAGTTGCTCCTCAAGGACTTCCTGAGATACAGTGAGAAGGCTGGTTTGGAGTGTTCAGATATTGAG AAAGCAGTGGAGTTAATGTGCCTTGTTCCCAAACGCTGCAATGACATGATGAATCTAGGACGTCTGCAG GGCTTTGAGGGCACTCTGACTGCTCAGGGGAAGCTGCTGCAGCAGGACACATTCTATGTGATCGAGCTG GATGCAGGCATGCAGTCCCGGACCAAAGAGAGGCGCGTGTTCCTCTTCGAGCAGATTGTCATCTTCAGT GAACTGCTCAGGAAGGGATCCCTCACCCCTGGCTACATGTTCAAAAGGAGCATCAAGATGAATTACTTG GTCCTGGAGGAGAATGTGGACAATGATCCCTGCAAGTTTGCACTCATGAACAGAGAGACTTCTGAGAGG GTTGTTCTGCAAGCCGCCAACGCTGACATCCAGCAGGCCTGGGTGCAGGACATCAATCAAGTCTTAGAA ACACAGCGAGACTTTTTGAATGCACTGCAATCGCCCATTGAGTATCAACGGAAAGAAAGGAGCACAGCT GTGATGAGGTCTCAACCTGCCAGGCTTCCCCAAGCCAGCCCCAGGCCCTACTCCTCTGTTCCTGCGGGC TCAGAGAAGCCCCCAAAGGGCTCCAGCTATAACCCACCTCTGCCTCCCCTGAAGATATCTACCTCCAAT GGCAGTCCAGGGTTTGAATACCACCAGCCTGGGGACAAGTTCGAAGCCAGCAAGCAGAACGACCTGGGA GGCTGCAATGGGACCTCGTCCATGGCCGTGATCAAAGATTACTATGCACTGAAGGAGAATGAAATCTGT GTGAGCCAAGGTGAGGTGGTCCAGGTCCTCGCCGTCAACCAGCAGAACATGTGTCTGGTGTACCAGCCT GCCAGCGACCATTCCCCCGCCGCCGAGGGCTGGGTCCCAGGCAGCATCCTGGCGCCCCTCACCAAAGCC ACAGCAGCAGAAAGTAGTGACGGGAGCATCAAGAAGTCATGTTCATGGCATACTCTACGCATGAGAAAG CGGGCGGAAGTGGAGAACACGGGTAAAAATGAAGCCACAGGGCCTCGTAAACCCAAGGATATTCTGGGC AACAAAGTCTCTGTTAAAGAGACGAACAGTTCCGAGGAATCAGAGTGTGATGATCTTGACCCTAATACT AGCATGGAGATCTTAAATCCAAATTTCATCCAAGAAGTGGCCCCAGAATTCCTTGTGCCCTTGGTGGAT GTGACCTGCTTGCTTGGGGACACAGTGATACTGCAGTGCAAAGTCTGTGGGCGGCCAAAGCCCACCATC ACTTGGAAGGGTCCAGACCAGAACATCCTTGACACTGATAACAGCTCAGCCACATACACGGTCTCCTCT TGTGATTCTGGAGAAATCACCCTGAAGATCTGTAATCTGATGCCCCAAGACAGTGGGATTTATACCTGC ATAGCAACAAATGACCACGGGACCACATCAACGTCTGCAACAGTCAAAGTGCAAGGTGTTCCAGCAGCC CCTAACCGCCCCATTGCCCAGGAGAGAAGCTGCACCTCCGTGATTCTCCGCTGGCTGCCCCCCTCCAGC ACAGGAAACTGCACTATTTCTGGTTACACTGTGGAGTACAGAGAGGAAGGTTCTCAGATCTGGCAGCAG TCAGTGGCTTCGACCTTGGACACTTACCTCGTCATCGAAGACCTTAGTCCCGGGTGTCCTTATCAGTTC AGAGTCAGTGCCAGTAACCCCTGGGGAATCAGCCTTCCCAGCGAGCCCTCGGAGTTTGTGCGACTTCCA GAATATGATGCTGCTGCTGATGGTGCCACCATTTCTTGGAAGGAAAATTTTGACTCAGCTTACACTGAG CTGAATGAAATTGGAAGAGGCCGTTTCTCTATAGTAAAGAAATGCATTCACAAAGCTACCCGCAAAGAT GTGGCTGTGAAATTTGTTAGCAAAAAAATGAAGAAGAAAGAACAGGCTGCCCACGAGGCTGCCCTGCTT CAGCACCTACAGCACCCCCAGTACATCACTCTCCATGACACCTATGAGTCCCCCACATCCTACATCCTG ATCTTGGAACTGATGGATGATGGCCGGCTCTTAGACTACCTTATGAATCATGATGAACTGATGGAGGAA AAAGTAGCTTTCTATATCCGAGACATCATGGAGGCTCTGCAGTACCTTCACAACTGCAGGGTTGCACAT TTGGACATAAAGCCTGAAAACCTGCTCATTGACCTACGGATTCCAGTGCCTCGAGTGAAGCTCATTGAC TTGGAGGATGCTGTCCAGATCTCGGGTCACTTCCACATTCACCACCTGCTGGGGAACCCTGAGTTTGCT GCCCCAGAAGTCATTCAAGGCATCCCCGTCTCCCTGGGGACAGACATCTGGAGCATCGGGGTTCTGACA TATGTCATGCTGAGTGGGGTCTCCCCCTTCTTGGATGAGAGCAAAGAGGAGACATGTATCAACGTATGC AGGGTGGATTTCAGCTTCCCCCATGAATACTTCTGTGGTGTGAGCAATGCTGCCAGAGATTTCATCAAT GTGATCTTACAGGAAGATTTTCGGAGGCGGCCCACAGCAGCCACATGCTTGCAGCATCCATGGCTGCAG CCCCATAATGGCAGCTACTCTAAGATCCCCCTGGACACCTCCCGCCTAGCATGCTTCATAGAACGTCGC AAGCACCAGAATGATGTGCGGCCTATTCCCAATGTCAAGAGCTACATTGTCAACCGGGTGAACCAAGGG ACGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_007064 |
| Insert Size | 3870 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_007064.4 |
| RefSeq Size | 10897 bp |
| RefSeq ORF | 3870 bp |
| Locus ID | 8997 |
| UniProt ID | O60229 |
| Domains | RhoGEF, pkinase, TyrKc, PH, S_TKc, ig, IGc2, IG, FN3 |
| Protein Families | Druggable Genome, Protein Kinase |
| MW | 144.5 kDa |
| Gene Summary | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. [provided by RefSeq, Apr 2016] Transcript Variant: This variant (3) differs in the 5' UTR and lacks many exons in the 5' coding region, compared to variant 1. The encoded protein (isoform 3), also known as Duo, is shorter and has a distinct N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218885 | KALRN (Myc-DDK-tagged)-Human kalirin, RhoGEF kinase (KALRN), transcript variant 3 |
CNY 8,976.00 |
|
| RC218885L1 | Lenti-ORF clone of KALRN (Myc-DDK-tagged)-Human kalirin, RhoGEF kinase (KALRN), transcript variant 3 |
CNY 11,376.00 |
|
| RC218885L2 | Lenti-ORF clone of KALRN (mGFP-tagged)-Human kalirin, RhoGEF kinase (KALRN), transcript variant 3 |
CNY 14,730.00 |
|
| RC218885L3 | Lenti-ORF clone of KALRN (Myc-DDK-tagged)-Human kalirin, RhoGEF kinase (KALRN), transcript variant 3 |
CNY 14,730.00 |
|
| RC218885L4 | Lenti-ORF clone of KALRN (mGFP-tagged)-Human kalirin, RhoGEF kinase (KALRN), transcript variant 3 |
CNY 14,730.00 |
|
| RG218885 | KALRN (tGFP-tagged) - Human kalirin, RhoGEF kinase (KALRN), transcript variant 3 |
CNY 14,160.00 |
