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ASIC3 (NM_004769) Human Untagged Clone
CAT＃: SC309761
ASIC3 (untagged)-Human amiloride-sensitive cation channel 3 (ACCN3), transcript variant 1
CNY 3,960.00
CNY 8,550.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ACCN3; DRASIC; SLNAC1; TNaC1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_004769 edited
GGGCGGCCGCGAATTCGGCACCAGCTGCCTTCCAACCTTGGCTTGTCTCCCACCCTCTCT TCTCCTCTCCTTGCCTGGCCTCCTGAATCCTATCTTAGCCTCCTTAGCCCCCTGACTGAC TCTCTCTCGCTTCTTCCAAGCCTCTGTAGCTGGTTCCGCTCCTGGGTTCTGGCCATGAAG CCCACCTCAGGCCCAGAGGAGGCCCGGCGGCCAGCCTCGGACATCCGCGTGTTCGCCAGC AACTGCTCGATGCACGGGCTGGGCCACGTCTTCGGGCCAGGCAGCCTGAGCCTGCGCCGG GGGATGTGGGCAGCGGCCGTGGTCCTGTCAGTGGCCACCTTCCTCTACCAGGTGGCTGAG AGGGTGCGCTACTACAGGGAGTTCCACCACCAGACTGCCCTGGATGAGCGAGAAAGCCAC CGGCTCATCTTCCCGGCTGTCACCCTGTGCAACATCAACCCACTGCGCCGCTCGCGCCTA ACGCCCAACGACCTGCACTGGGCTGGGTCTGCGCTGCTGGGCCTGGATCCCGCAGAGCAC GCCGCCTTCCTGCGCGCCCTGGGCCGGCCTCCTGCACCGCCCGGCTTCATGCCCAGTCCC ACCTTTGACATGGCGCAACTCTATGCCCGTGCTGGGCACTCCCTGGATGACATGCTGCTG GACTGTCGCTTCCGTGGCCAACCTTGTGGGCCTGAGAACTTCACCACGATCTTCACCCGG ATGGGAAAGTGCTACACATTTAACTCTGGCGCTGATGGGGCAGAGCTGCTCACCACTACT AGGGGTGGCATGGGCAATGGGCTGGACATCATGCTGGACGTGCAGCAGGAGGAATATCTA CCTGTGTGGAGGGACAATGAGGAGACCCCGTTTGAGGTGGGGATCCGAGTGCAGATCCAC AGCCAGGAGGAGCCGCCCATCATCGATCAGCTGGGCTTGGGGGTGTCCCCGGGCTACCAG ACCTTTGTTTCTTGCCAGCAGCAGCAGCTGAGCTTCCTGCCACCGCCCTGGGGCGATTGC AGTTCAGCATCTCTGAACCCCAACTATGAGCCAGAGCCCTCTGATCCCCTAGGCTCCCCC AGCCCCAGCCCCAGCCCTCCCTATACCCTTATGGGGTGTCGCCTGGCCTGCGAAACCCGC TACGTGGCTCGGAAGTGCGGCTGCCGAATGGTGTACATGCCAGGCGACGTGCCAGTGTGC AGCCCCCAGCAGTACAAGAACTGTGCCCACCCGGCCATAGATGCCATGCTTCGCAAGGAC TCGTGCGCCTGCCCCAACCCGTGCGCCAGCACGCGCTACGCCAAGGAGCTCTCCATGGTG CGGATCCCGAGCCGCGCCGCCGCGCGCTTCCTGGCCCGGAAGCTCAACCGCAGCGAGGCC TACATCGCGGAGAACGTGCTGGCCCTGGACATCTTCTTTGAGGCCCTCAACTATGAGACC GTGGAGCAGAAGAAGGCCTATGAGATGTCAGAGCTGCTTGGTGACATTGGGGGCCAGATG GGGCTGTTCATCGGGGCCAGCCTGCTCACCATCCTCGAGATCCTAGACTACCTCTGTGAG GTGTTCCGAGACAAGGTCCTGGGATATTTCTGGAACCGACAGCACTCCCAAAGGCACTCC AGCACCAATCTGCTTCAGGAAGGGCTGGGCAGCCATCGAACCCAAGTTCCCCACCTCAGC CTGGGCCCCAGACCTCCCACCCCTCCCTGTGCCGTCACCAAGACTCTCTCCGCCTCCCAC CGCACCTGCTACCTTGTCACACAGCTCTAGACCTGCTGTCTGTGTCCTCGGAGCCCCGCC CTGACATCCTGGACATGCCTAGCCTGCACGTAGCTTTTCCGTCTTCACCCCAAATAAAGT CCTAATGCATCAGCAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCG >OriGene 5' read for NM_004769 unedited
NTATATCGCCGACCCCTTGTCCCAATGGGCGGTAGGCGTGTACAGTGGGCAGGTCTATAT AAGCAGAGCTTGTTTAGTGAACCGTCAGTATTTTGTAATACGACTCACTATAGGGCGGCT CGCGAATTCGGCACCAGCTGCCTTCCAACCTTGGCTTGTCTCCCACCCTCTCTTCTCCTC TCCTTGCCTGGCCTCCTGAATCCTATCTTAGCCTCCTTAGCCCCCTGACTGACTCTCTCT CGCTTCTTCCAAGCCTCTGTAGCTGGTTCCGCTCCTGGGTTCTGGCCATGAAGCCCACCT CAGGCCCAGAGGAGGCCCGGCGGCCAGCCTCGGACATCCGCGTGTTCGCCAGCAACTGCT CGATGCACGGGCTGGGCCACGTCTTCTGGCCAGGCATCCTGAGCCTGCGCCGGGGGATGT GGGCAGCGGCCGTGGTCCTGTCAGTGGCCACCTTCCTCTACCAGGTGGCTGAGAGGGTGC GCTACTACAGGGAGTTCCACCACCAGACTGCCCTGGATGAGCGAGAAAGCCACCGGCTCA TCTTCCCGGCTGTCACCCTGTGCAACATCAACCCACTGCGCCGCTCGCGCCTAACGCCCA ACGACCTGCACTGGGCTGGGTCTGCGCTGCTGGGCCTGGATCCCGCAGAGCACGCCGCCT TCCTGCGCGCCCTGGGCCGGCCTCCTGCACCGCCCGGCTTCATGCCCAGTCCCACCTTTG ACATGACGCAACTCTATGCCCGTGCTAGGCACTCCCTGNATGACATGCTGCTGGACTGTC GCTTACCGTGGCCAACCTTTGTGGGCCTGAGAACTTCACCACGATCTTCACCCGGATGGG GAAAGTGCTACACATTTTACTCCTGCGCTGATGGGGCAGAACTGCTCACACTCTAAGGGT GGCATGGGCA >OriGene 3' read for NM_004769 unedited
NNTTGTTGCATTAGGACTTTTTTGGGGTNGAANCGGNAAAACTACGTGCAGGCTAGGCAT GTCCAGGATGTCAGGGCGGGGCTCCGAGGACACAGACAGCAGGTCTAGAGCTGTGTGACA AGGTAGCAGGTGCGGTGGGAGGCGGAGAGAGTCTTGGTGACGGCACAGGGAGGGGTGGGA GGTCTGGGGCCCAGGCTGAGGTGGGGAACTTGGGTTCGATGGCTGCCCAGCCCTTCCTGA AGCAGATTGGTGCTGGAGTGCCTTTGGGAGTGCTGTCGGTTCCAGAAATATCCCAGGACC TTGTCTCGGAACACCTCACAGAGGTAGTCTAGGATCTCGAGGATGGTGAGCAGGCTGGCC CCGATGAACAGCCCCATCTGGCCCCCAATGTCACCAAGCAGCTCTGACATCTCATAGGCC TTCTTCTGCTCCACGGTCTCATAGTTGAGGGCCTCAAAGAAGATGTCCAGGGCCAGCACG TTCTCCGCGATGTAGGCCTCGCTGCGGTTGAGCTTCCGGGCCAGGAAGCGCGCGGCGGCG CGGCTCGGGATCCGCACCATGGAGAGCTCCTTGGCGTAGCGCGTGCTGGCGCACGGGTTG GGGCAGGCGCACGAGTCCTTGCGAAGCATGGCATCTATGGCCGGGTGGGCACAGTTCTTG TACTGCTGGGGGCTGCACACTGGCACGTCGCCTGGCATGTACACCATTCGGCAGCCGCAC TTCCGAGCCACGTAGCGGGTTTCGCAGGCCAGGCGACACCCCATAAGGGTATAGGGAGGG CTGGGGCTGGGGCTGGGGGAGCCTAAGGGATCAAAGGGCTCTGGCTCATAGTTTGGGGTT CAGAGATGCTGAACTGCAATCGCCCCCAGGCGGTGGCCAGAAGCTCAACTGCTGCTGCTG GCAAAC |
| Restriction Sites | Please inquire |
| ACCN | NM_004769 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004769.1, NP_004760.1 |
| RefSeq Size | 1746 bp |
| RefSeq ORF | 1596 bp |
| Locus ID | 9311 |
| UniProt ID | Q9UHC3 |
| Protein Families | Druggable Genome, Ion Channels: Other |
| Gene Summary | This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012] Transcript Variant: This variant (1) uses an alternate splice site in the 3' coding region, compared to variant 2. The resulting protein (isoform a) has a shorter and distinct C-terminus, compared to isoform b. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220582 | ASIC3 (Myc-DDK-tagged)-Human amiloride-sensitive cation channel 3 (ACCN3), transcript variant 1 |
CNY 3,952.00 |
|
| RC220582L1 | Lenti ORF clone of Human amiloride-sensitive cation channel 3 (ACCN3), transcript variant 1, Myc-DDK-tagged |
CNY 6,352.00 |
|
| RC220582L2 | Lenti ORF clone of Human amiloride-sensitive cation channel 3 (ACCN3), transcript variant 1, mGFP tagged |
CNY 6,460.00 |
|
| RC220582L3 | Lenti ORF clone of Human amiloride-sensitive cation channel 3 (ACCN3), transcript variant 1, Myc-DDK-tagged |
CNY 6,352.00 |
|
| RC220582L4 | Lenti ORF clone of Human amiloride-sensitive cation channel 3 (ACCN3), transcript variant 1, mGFP tagged |
CNY 6,352.00 |
|
| RG220582 | ASIC3 (tGFP-tagged) - Human amiloride-sensitive cation channel 3 (ACCN3), transcript variant 1 |
CNY 5,552.00 |
