NFAT5 (NM_006599) Human Untagged Clone
CAT#: SC309614
NFAT5 (untagged)-Human nuclear factor of activated T-cells 5, tonicity-responsive (NFAT5), transcript variant 3
CNY 10,450.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | NF-AT5; NFATL1; NFATZ; OREBP; TONEBP |
Vector | pCMV6 series |
Sequence Data |
>NCBI ORF sequence for NM_006599, the custom clone sequence may differ by one or more nucleotides
ATGCCCTCGGACTTCATCTCATTGCTCAGCGCGGACCTAGACCTGGAATCGCCCAAGTCC CTCTACTCGCGAGAATCTGTCTATGATCTTCTCCCAAAGGAGTTACAGTTACCTCCATCT AGAGAAACATCTGTAGCATCAATGAGTCAGACAAGCGGTGGTGAGGCAGGCTCGCCTCCT CCAGCTGTTGTTGCTGCTGATGCTTCTTCAGCTCCCTCCTCTTCCTCCATGGGCGGTGCT TGCAGCTCCTTTACCACCTCTTCCAGCCCTACCATTTATTCTACCTCAGTCACCGACAGC AAGGCTATGCAAGTGGAGAGCTGCTCCTCAGCCGTGGGGGTAAGTAACAGAGGGGTAAGT GAAAAGCAGTTAACCAGTAACACAGTTCAGCAGCATCCATCAACACCGAAGAGGCACACA GTCTTGTACATCTCACCACCACCTGAGGACTTGCTGGATAACAGTCGGATGTCCTGCCAG GATGAGGGGTGTGGATTGGAATCTGAGCAGAGCTGCAGTATGTGGATGGAGGATTCCCCC TCCAACTTCAGTAACATGAGCACCAGTTCCTACAATGATAACACTGAGGTACCTCGTAAA TCACGAAAACGAAATCCAAAGCAGAGGCCGGGGGTCAAACGACGAGATTGTGAAGAATCT AATATGGATATATTTGATGCCGACAGTGCCAAAGCACCTCACTATGTGCTTTCTCAGCTT ACCACGGACAACAAAGGCAACTCAAAAGCGGGAAATGGAACATTGGAAAACCAAAAAGGA ACTGGAGTAAAGAAGAGCCCTATGTTGTGTGGACAATATCCTGTTAAAAGTGAGGGAAAG GAGCTGAAGATAGTTGTACAACCTGAGACACAGCACCGAGCTCGGTACCTGACTGAGGGC AGCCGTGGCTCAGTGAAAGATAGAACACAGCAAGGCTTTCCTACAGTAAAGCTGGAAGGC CATAATGAACCTGTAGTGTTGCAAGTGTTTGTGGGCAACGACTCTGGACGAGTGAAACCA CATGGATTTTATCAGGCCTGCAGAGTAACTGGACGAAATACAACTCCTTGCAAAGAAGTG GACATTGAAGGCACTACTGTTATAGAAGTCGGCCTTGATCCTAGCAACAACATGACACTG GCGGTGGACTGCGTAGGGATATTGAAATTGAGGAATGCTGATGTCGAAGCCAGAATAGGA ATTGCTGGTTCCAAGAAGAAAAGCACTCGTGCCAGATTGGTTTTTCGAGTTAATATCATG AGGAAAGATGGCTCCACTTTGACACTGCAAACACCCTCTTCTCCAATTTTGTGTACTCAG CCAGCAGGAGTGCCAGAAATCTTAAAGAAAAGCTTGCATAGCTGTTCAGTGAAAGGAGAA GAAGAAGTGTTTTTAATCGGCAAGAACTTTCTGAAAGGAACTAAAGTTATTTTCCAAGAA AATGTTTCTGATGAAAACTCTTGGAAGTCAGAAGCTGAAATTGATATGGAACTATTTCAT CAGAATCATCTTATTGTGAAGGTTCCTCCCTATCATGACCAACATATAACTTTGCCTGTG TCAGTGGGAATATATGTAGTGACAAATGCTGGAAGATCTCATGATGTTCAACCATTCACT TACACTCCAGACCCAGCAGCAGCTGGTGCTTTGAATGTAAATGTGAAGAAGGAAATATCT AGTCCAGCAAGACCTTGCTCTTTTGAAGAGGCCATGAAAGCAATGAAAACTACTGGATGT AATTTAGATAAGGTAAATATTATCCCTAATGCCCTGATGACTCCACTCATACCAAGCAGT ATGATTAAGAGTGAAGATGTTACTCCAATGGAAGTAACAGCAGAAAAAAGATCTTCCACT ATTTTTAAGACTACAAAGTCTGTTGGATCAACTCAGCAAACATTAGAAAACATCTCAAAC ATAGCAGGAAATGGCTCTTTTTCATCACCATCATCTTCCCACCTACCTTCTGAAAATGAA AAACAGCAGCAGATTCAGCCCAAGGCATACAACCCAGAGACCCTGACAACTATTCAAACC CAGGACATCTCACAGCCTGGTACTTTTCCAGCAGTTTCTGCTTCTAGTCAGCTGCCCAAC AGCGATGCACTATTGCAGCAGGCTACACAGTTTCAGACAAGAGAAACTCAGTCTAGAGAG ATATTACAGTCAGATGGTACAGTGGTTAATTTGTCACAACTGACTGAGGCATCACAACAA CAGCAGCAGTCACCACTACAAGAACAAGCACAGACTTTACAGCAGCAGATTTCATCAAAT ATTTTTCCATCACCAAATAGTGTGAGTCAGCTTCAGAATACTATTCAGCAGCTGCAAGCA GGGAGTTTCACAGGCAGTACTGCTAGTGGCAGCAGTGGAAGTGTTGACTTGGTCCAACAA GTTTTAGAGGCACAGCAGCAGTTATCTTCAGTTTTATTTTCTGCTCCAGATGGTAATGAG AATGTTCAAGAGCAGCTTAGTGCAGATATTTTTCAACAAGTCAGTCAAATTCAGAGTGGT GTAAGCCCTGGAATGTTTTCCTCAACAGAGCCAACAGTCCATACCAGACCAGATAATTTA TTACCTGGAAGAGCTGAAAGTGTTCATCCACAGTCTGAAAACACGTTATCTAATCAACAG CAGCAGCAGCAGCAGCAACAGCAAGTGATGGAATCTTCAGCCGCAATGGTGATGGAGATG CAACAGAGTATCTGCCAGGCAGCTGCCCAGATTCAGTCAGAGTTATTCCCTTCAACTGCT TCAGCAAATGGAAACCTTCAGCAATCGCCAGTTTACCAGCAGACTTCTCACATGATGAGT GCATTGTCTACCAATGAGGATATGCAAATGCAGTGTGAATTGTTTTCTTCTCCTCCTGCA GTTTCTGGAAATGAAACTTCTACAACTACCACACAGCAGGTTGCAACCCCTGGCACTACC ATGTTTCAGACATCAAGTTCAGGAGATGGAGAAGAAACTGGAACACAAGCAAAACAGATT CAGAACAGTGTCTTTCAGACCATGGTCCAAATGCAACATAGTGGGGACAATCAACCTCAA GTTAACCTTTTTTCATCCACAAAAAGTATGATGAGTGTTCAGAATAGTGGTACCCAACAA CAAGGTAATGGTTTATTCCAGCAAGGGAATGAGATGATGTCACTTCAATCTGGAAATTTT TTGCAGCAGTCTTCTCATTCACAGGCCCAACTTTTTCATCCTCAAAATCCTATTGCCGAT GCTCAGAACCTTTCCCAGGAAACTCAAGGTTCTCTCTTTCATAGTCCAAATCCTATTGTC CACAGTCAGACTTCTACAACCTCCTCTGAACAAATGCAGCCTCCAATGTTTCACTCTCAA AGTACCATTGCTGTGTTACAGGGCTCTTCAGTTCCTCAAGACCAGCAGTCAACCAACATA TTTCTTTCCCAGAGTCCCATGAATAATCTTCAGACTAACACAGTAGCCCAAGAAGCATTT TTTGCAGCACCGAACTCAATTTCTCCACTTCAGTCAACATCAAACAGTGAACAACAAGCT GCTTTCCAACAGCAAGCTCCAATATCACACATCCAGACTCCTATGCTTTCCCAAGAACAG GCACAACCCCCGCAGCAGGGTTTATTTCAGCCTCAGGTGGCCCTGGGCTCCCTTCCACCT AATCCAATGCCTCAAAGCCAACAAGGAACCATGTTCCAGTCACAGCACTCAATAGTTGCC ATGCAGAGTAACTCTCCATCCCAGGAACAGCAGCAGCAGCAGCAACAGCAGCAGCAACAG CAGCAGCAACAACAACAGAGCATTTTATTCAGTAATCAGAATACCATGGCTACAATGGCG TCTCCAAAGCAACCACCACCAAACATGATATTCAACCCAAATCAAAATCCAATGGCTAAT CAGGAGCAACAGAACCAGTCAATTTTTCACCAACAAAGTAACATGGCCCCAATGAATCAA GAGCAACAGCCCATGCAATTTCAGAGTCAGTCCACAGTTTCCTCACTTCAGAACCCAGGT CCTACCCAGTCGGAATCATCACAGACCCCCTTGTTCCATAGCTCTCCTCAGATTCAGTTG GTACAAGGGTCACCTAGTTCTCAAGAGCAGCAAGTAACTCTCTTCTTATCTCCAGCATCC ATGTCTGCCTTGCAGACCAGTATAAATCAACAAGATATGCAACAGTCTCCTCTTTATTCC CCTCAGAACAACATGCCTGGAATTCAAGGAGCCACATCTTCGCCTCAACCACAGGCTACT TTATTTCACAACACAGCAGGAGGCACAATGAACCAACTGCAGAATTCTCCTGGCTCATCT CAGCAGACATCAGGAATGTTCTTATTTGGCATTCAAAATAACTGTAGTCAGCTTTTAACC TCTGGACCAGCTACATTGCCTGATCAGTTGATGGCCATAAGTCAGCCAGGCCAACCACAA AACGAGGGCCAGCCACCTGTGACAACACTTCTTTCTCAGCAAATGCCAGAGAATTCTCCA CTGGCATCCTCTATAAACACCAACCAGAACATCGAAAAGATTGATTTGCTTGTTTCATTG CAAAACCAAGGGAACAACTTGACTGGCTCCTTTTAA |
Restriction Sites | Please inquire |
ACCN | NM_006599 |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_006599.2, NP_006590.1 |
RefSeq Size | 14123 bp |
RefSeq ORF | 4596 bp |
Locus ID | 10725 |
UniProt ID | O94916 |
Domains | IPT |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Axon guidance, B cell receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway |
Gene Summary | The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) lacks two exons in the 5' region, compared to variant 1. This difference causes translation initiation at an upstream start codon and results in an isoform (c) with a longer N-terminus compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Product Manuals |
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SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC216142 | NFAT5 (Myc-DDK-tagged)-Human nuclear factor of activated T-cells 5, tonicity-responsive (NFAT5), transcript variant 3 |
CNY 16,760.00 |
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RC216142L3 | Lenti-ORF clone of NFAT5 (Myc-DDK-tagged)-Human nuclear factor of activated T-cells 5, tonicity-responsive (NFAT5), transcript variant 3 |
CNY 17,200.00 |
|
RC216142L4 | Lenti-ORF clone of NFAT5 (mGFP-tagged)-Human nuclear factor of activated T-cells 5, tonicity-responsive (NFAT5), transcript variant 3 |
CNY 17,200.00 |
|
RG216142 | NFAT5 (tGFP-tagged) - Human nuclear factor of activated T-cells 5, tonicity-responsive (NFAT5), transcript variant 3 |
CNY 16,820.00 |