ARHGEF11 (NM_198236) Human Untagged Clone
CAT#: SC309608
ARHGEF11 (untagged)-Human Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 2
CNY 10,450.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | GTRAP48; PDZ-RHOGEF |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_198236 edited
CCCACGCGTCCGCCCACGCGTCCGAGCGAAATCTCCGTTTCATGGAGGCTGAGGCAAGAG AAAATTTCGGAGCCTGGATGTGGAGGAGCCCAACAGCAGAACTAACTCAGGAAATTGTCT TTCAGAAAAAGGCCGAACGTAGGCTGGGTCTGAGAATCAGGCTGGGGTAGGTGGAGGAAC CTGCAAGTTTAAAGGAAAAAGAAAAGGAGAGAATATTTTCAGTGATTATCTCTGGTTTGT TATCATTACTACCATCTTAAAGGTAAAAAGCATTGCATTTCAGGTGTTCTTTGATTTTTA TTTTATTTTTTTTTTTGGTGCAATTGGCTCATTTAAGAATTTCAAAACATTTAATGTAAA AGCTTTTTTTTTTTT::AA:GGAAGTCCATAAATTTTGGTTCCCAGGGTTGCACTGGACT TGGAAGGAGTGCTGTTGTGTACATACTATTGTATGGTTTTATTTATTATTTTACTGTACA AATCAGCTGAAAGAATTTTTCCAAGTGCCATTTCGGATTTATTAATCCTTTTTTTTTTCC TTTCCTCAAAGATATTTGCTGTTGTCATATTAAGCATTGGAGACTAGAAAATTACTTTCC CCCTTTGAGCTAGAGGGTCTCTTGCCAACAGAAGGACAGCTGAGAAAGCTGGATTTAAAG GATGGTTTTATCTGTACTTTGCAGTTAACAGTGATATTTTGAAGGCACATTTTTCTGTGA TTCATTTTTTTTTGGCCATAGTGCTAACCTTGAAGAGATTCGTGGCTGGGTTTTTGGTTT CTGAGAAGGTCGTAGTTTTTCCTCTTTTCCTTTTTTTTTCTTTTTTCTTTTCTTTTCTTT TTTTTTAAAGCGGGGGAGGGGAAGAGGGGCTGAGAAAGGAAATCATGTTCACTGGTAGAA GTAGAGTGGAGCATCAGTTACCAGGGTCCTGAGAGCTGGAGGAGAAAGGATTCTATCTTC AAGTTGGGAGGCCCTCCTCTCACCTTGCTCAAAAATTGCAAGCGATTCAATCCTGATCAA GACACCAAAGCTACAGGATTCTGGAACCGTGGAGACACCGAGAAACCATGAGTGTAAGGT TACCCCAGAGTATAGACAGGTTAAGTAGCCTGTCTTCTCTGGGAGATTCTGCACCAGAGC GCAAGTCCCCTTCCCACCATCGCCAGCCTTCGGATGCCTCTGAGACAACAGGTCTCGTTC AACGCTGTGTCATTATCCAAAAGGACCAGCATGGCTTCGGCTTCACAGTCAGTGGGGATC GCATTGTTCTGGTGCAGTCTGTGCGGCCTGGAGGTGCAGCCATGAAGGCCGGTGTGAAAG AGGGCGACCGGATCATCAAAGTCAACGGCACCATGGTGACCAATAGCTCACACCTGGAAG TGGTAAAGCTGATCAAATCTGGCGCCTATGTCGCACTCACCCTCCTGGGCTCTTCACCTT CATCCATGGGCATCTCTGGGCTCCAGCAGGACCCATCCCCAGCAGGAGCTCCCCGAATCA CGTCAGTGATCCCCTCACCACCACCTCCTCCACCTCTACCACCTCCACAACGCATCACAG GACCCAAACCTCTGCAGGATCCCGAAGTTCAAAAACATGCCACCCAGATCCTCAGGAATA TGCTGAGGCAGGAAGAAAAAGAATTACAGCGTATCTGTGAGGTCTATAGCCGGAACCCCG CCAGCCTACTGGAAGAGCAGATCGAAGGTGCCCGGCGGCGAGTCACTCAGTTACAGCTGA AGATCCAGCAGGAGACTGGTGGCTCAGTGGACATACTTCCACTATATGGTGACACCAGCC AGAGACCATCAGAAGGCCGGCTCTCTCTGGATTCCCAGGAGGGGGACAGTGGCTTGGACT CTGGGACAGAACGCTTTCCTTCCCTCAGTGAGTCATTGATGAATCGGAACTCGGTACTGT CAGACCCTGGGCTAGACAGTCCTCGAACCTCCCCTGTGATCATGGCCAGGGTGGCCCAGC ACCACAGGCGGCAGGGCTCGGATGCAGCAGTCCCCTCAACCGGTGACCAGGGTGTAGATC AAAGCCCAAAGCCTTTAATTATTGGCCCAGAGGAAGACTATGACCCGGGTTATTTCAACA ACGAGAGCGACATCATATTCCAGGATCTGGAGAAACTGAAGTCTCGGCCAGCTCACCTGG GGGTTTTTCTACGTTACATCTTCTCTCAGGCGGACCCCAGTCCACTGCTTTTTTACCTGT GTGCAGAAGTTTATCAGCAGGCAAGCCCCAAGGATTCCCGAAGCTTGGGGAAAGACATCT GGAATATTTTCCTGGAGAAAAATGCGCCTCTGAGAGTGAAGATCCCTGAGATGCTACAGG CTGAAATTGACTCGCGCCTGCGGAACAGCGAAGATGCCCGTGGTGTTCTCTGTGAAGCTC AAGAGGCAGCCATGCCTGAGATCCAAGAGCAGATCCACGACTACAGAACGAAGCGCACAC TGGGGCTGGGCAGCCTGTATGGTGAAAATGACCTGCTGGACCTGGATGGGGACCCTCTCC GAGAGCGCCAAGTGGCTGAGAAGCAGCTGGCTGCCCTTGGAGATATTTTGTCCAAGTATG AGGAAGACAGGAGCGCCCCCATGGACTTCGCCCTCAATACCTACATGAGCCATGCTGGGA TCCGTCTTCGAGAGGCACGACCTTCCAACACAGCTGAAAAGGCCCAGTCTGCTCCTGACA AGGACAAGTGGCTACCGTTCTTCCCTAAGACCAAGAAGAGCAGCAATTCCAAGAAAGAAA AGGATGCCTTGGAGGACAAGAAGCGAAACCCTATCCTCAAATACATTGGGAAGCCCAAAA GCTCTTCTCAAAGCACATTTCATATTCCCTTGTCCCCTGTGGAAGTCAAACCAGGCAATG TGAGGAACATCATTCAGCACTTTGAGAACAACCAGCAGTATGATGCCCCAGAACCTGGGA CACAACGACTCTCGACCGGAAGCTTTCCTGAGGACCTGCTGGAGAGTGACAGTTCACGCT CAGAGATTCGCCTGGGCCGCTCTGAAAGCCTCAAGGGCCGGGAAGAGATGAAACGGTCTC GAAAGGCAGAGAACGTGCCCCGCTCTCGCAGTGATGTTGACATGGATGCTGCTGCGGAGG CTACTCGCCTGCACCAGTCAGCCTCGTCCTCTACCTCCAGCCTCTCCACCAGGTCTCTTG AGAACCCAACCCCTCCATTCACTCCCAAAATGGGCCGCAGGAGCATTGAGTCCCCCAGTT TGGGGTTCTGCACAGATACCCTCCTTCCCCACCTCCTAGAGGATGATCTGGGCCAGCTGT CTGACCTGGAGCCAGAGCCAGATGCCCAAAATTGGCAGCATACAGTGGGCAAGGATGTGG TGGCTGGGCTAACCCAGCGGGAGATTGACCGGCAAGAGGTCATCAATGAGCTGTTTGTGA CTGAAGCTTCCCACCTGCGCACACTCCGGGTCCTGGACCTGATCTTCTACCAGCGAATGA AGAAGGAGAACCTGATGCCCCGGGAGGAGCTGGCCCGGCTCTTCCCGAACCTGCCTGAAC TCATAGAGATTCACAATTCCTGGTGTGAAGCCATGAAGAAGCTCCGGGAGGAAGGCCCCA TCATCAAAGAGATCAGTGACCTCATGCTGGCCCGGTTTGATGGCCCTGCCCGAGAGGAAC TCCAGCAAGTGGCTGCACAGTTCTGTTCCTATCAGTCAATAGCCCTAGAGCTAATCAAGA CCAAGCAACGCAAGGAGAGTCGATTCCAGCTCTTCATGCAGGAGGCTGAGAGCCACCCTC AGTGTCGGCGGCTGCAGCTGAGAGACCTCATCATCTCTGAGATGCAGCGGCTCACCAAGT ACCCGCTGCTGCTGGAGAGCATCATCAAGCACACAGAGGGTGGCACCTCTGAGCATGAGA AGCTGTGCCGGGCCCGGGACCAGTGCCGGGAGATTCTCAAGTATGTGAATGAAGCGGTAA AACAAACAGAGAACCGCCACCGTTTAGAGGGCTACCAGAAACGCCTGGATGCCACCGCCC TGGAGAGGGCCAGCAACCCCCTGGCAGCAGAGTTCAAGAGCCTGGATCTTACAACCAGAA AAATGATCCATGAGGGACCCCTGACCTGGAGGATCAGCAAGGATAAGACCTTGGACCTCC ACGTGCTGCTGCTGGAGGACCTCCTAGTGCTGCTACAGAAACAGGATGAGAAGCTATTGC TGAAGTGCCACAGCAAGACTGCTGTGGGCTCCTCAGACAGCAAGCAGACCTTCAGCCCCG TGCTCAAGCTCAATGCTGTGCTCATCCGCTCTGTGGCCACAGATAAACGGGCCTTCTTCA TCATCTGCACCTCCAAGCTGGGCCCACCCCAGATCTATGAGCTGGTTGCATTGACGTCAT CAGACAAGAACACATGGATGGAGCTCTTAGAAGAGGCCGTGCGGAATGCCACCAGGCACC CCGGAGCTGCCCCAATGCCCGTCCATCCTCCACCCCCAGGTCCCCGGGAGCCAGCCCAGC AGGGCCCCACACCCAGCAGGGTAGAACTGGATGACTCAGACGTGTTCCATGGTGAACCTG AACCTGAGGAGCTGCCTGGAGGCACTGGGTCCCAGCAGAGGGTCCAAGGGAAGCACCAGG TCCTGCTAGAGGACCCTGAGCAGGAGGGCAGTGCAGAGGAAGAGGAACTGGGTGTCCTGC CTTGCCCTTCCACATCCCTGGATGGAGAGAACAGGGGCATCAGGACAAGGAACCCCATCC ACTTGGCCTTCCCAGGCCCTCTGTTCATGGAAGGGCTCGCTGACTCCGCTCTGGAAGATG TGGAGAACCTGCGACATCTGATCCTGTGGAGCCTGCTGCCAGGTCACACCATGGAAACTC AGGCTGCCCAGGAGCCCGAGGACGACCTGACACCCACACCTTCTGTCATCAGCGTCACCT CTCACCCCTGGGACCCAGGCTCCCCAGGGCAAGCACCCCCTGGGGGTGAAGGGGACAACA CCCAGCTTGCAGGGCTGGAGGGGGAACGGCCAGAGCAGGAAGACATGGGTCTCTGTTCTC TGGAACACCTACCCCCAAGGACCAGAAATTCTGGGATATGGGAGTCTCCAGAACTGGACA GGAATCTGGCTGAAGATGCTTCAAGCACAGAGGCAGCAGGAGGTTACAAAGTTGTGAGAA AAGCTGAGGTGGCAGGCAGCAAGGTTGTCCCTGCACTACCAGAGAGTGGCCAGTCAGAGC CTGGGCCACCTGAAGTGGAAGGCGGAACAAAGGCTACGGGGAACTGCTTTTATGTCAGCA TGCCATCAGGACCCCCGGACTCAAGCACCGACCACTCAGAGGCACCCATGAGCCCCCCTC AGCCTGACAGCCTCCCTGCAGGGCAGACAGAGCCTCAGCCTCAGCTGCAGGGAGGCAACG ATGATCCAAGACGCCCCAGCCGCTCTCCTCCAAGCCTGGCCCTCAGGGACGTGGGCATGA TCTTCCATACCATTGAGCAGCTCACTCTCAAGCTCAACAGGCTCAAGGATATGGAGCTGG CCCACAGAGAGCTGCTCAAGTCCCTTGGGGGAGAGTCATCTGGTGGCACCACGCCTGTGG GCAGTTTCCACACAGAAGCAGCTAGATGGACAGATGGCTCCCTCTCACCTCCCGCTAAGG AGCCCCTAGCTTCTGACTCCAGGAACAGCCATGAACTGGGGCCCTGCCCTGAGGATGGCT CTGACGCCCCCCTGGAAGACAGCACAGCAGACGCAGCCGCGTCACCAGGACCATAACCGT ACAAACCACCAAATCCTCTGCGTCCCCACTCCTCCTTCAGGGACTGGCCTGAGACCGGGG CACAGGGTAGGGGGGATCCCAACACTCCTCCCTGTGGAGGAGGCAGTTAGGGAAACTAGG ATCCAGCCAAGGCCCGGGGGGAGACCCGCATGTTGCTTGGTCTGCTCAAGTCGGAGTCAG GTTTCAGTGTCTTTTCCCTCCCTTAGCCCAACCCTCCAAGGCCTCATGTCTCCTAAGCAT GCTGACTGCATCCGAAAGGCCCCCACTCACCATGGTCTGCCCTCACCCCACATATGTGTG TACACGCGCACGCCTGTATGTGCGCTGCCCTCAGACATGCAAGTGAAAGGAGGAGGCTTC TGTGTAAATGCACTTTCTTCCTCCCCTCTTTCTCCATAAGACCCCAGGCAGAGGTGGGTG CCTCCCCTCCCCTCTTTGTCACTTTGGTTTCCTATAAATATGTATGTATCGTATGTGCAT CTTTGCTATTGTAAATAACTTTGACCTTTTTTGTTCCTGTTCCTGAAGTGCTGGAGGCAG TTATGGAAGGAGCTGCTTAGGGAAGAGGGGTTTCACTTGTATCTCCTTAGTTAACAACCC AGTTCCAGGATCGAGCCTAAAGCGGGAGCCAGGCCTGAGTGTTCCTGTCCCTGTGAGTGG GAAGGTCTTCTGGCTCCCCATCCCACCTGGCTCCAGAGCCTGCCCTCCACAGCTTGCTGC CAAGCTACTCCCTCCCTCCCTGGACTTCTCATCTTCACAAGATGGGGATCATGGGGGTTT CTTACCCCACCTATGTCCCCCTCTTCCCCACCCTGTCCCTGTAGAAAACCAGTGAAGCAG GTACGGAGCTGAGGACTGGGCCCCAGGAGGTGGGGACAGGGGTCTGAATGCCGAGTCCCT GAATTCACCCAGGACCATCCAAGGGGCCACCGCAGCATTGGCCCCATCACCACGTCCTCA CCCAACTCTCCCTGATGAATAGAATATACACACTGTGCTAGGTGTATATATACATATATA TATATATAAATATATATATAATATATAAAATATAGATATGGAAATGACTGTTCTGCTGTT AAGATAATGTATACTCTTTTATTTTCTTCCTTTCATGGTTAAGATTTTTTTTTTAAGAAA AGTTAAATATCCTTCAAAAAAAAAAAAAAAA |
Restriction Sites | Please inquire |
ACCN | NM_198236 |
Insert Size | 6900 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_198236.1. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_198236.1, NP_937879.1 |
RefSeq Size | 6904 bp |
RefSeq ORF | 4689 bp |
Locus ID | 9826 |
UniProt ID | O15085 |
Protein Families | Druggable Genome |
Protein Pathways | Vascular smooth muscle contraction |
Gene Summary | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) contains an alternate in-frame exon, compared to variant 1. The resulting protein (isoform 2) is longer, compared to isoform 1. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC208729 | ARHGEF11 (Myc-DDK-tagged)-Human Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 2 |
CNY 10,688.00 |
|
RC208729L1 | Lenti-ORF clone of ARHGEF11 (Myc-DDK-tagged)-Human Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 2 |
CNY 13,088.00 |
|
RC208729L2 | Lenti-ORF clone of ARHGEF11 (mGFP-tagged)-Human Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 2 |
CNY 17,480.00 |
|
RC208729L3 | Lenti-ORF clone of ARHGEF11 (Myc-DDK-tagged)-Human Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 2 |
CNY 17,480.00 |
|
RC208729L4 | Lenti-ORF clone of ARHGEF11 (mGFP-tagged)-Human Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 2 |
CNY 17,480.00 |
|
RG208729 | ARHGEF11 (tGFP-tagged) - Human Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 2 |
CNY 12,288.00 |
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