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MSH5 (NM_172166) Human Untagged Clone
CAT＃: SC309519
MSH5 (untagged)-Human mutS homolog 5 (E. coli) (MSH5), transcript variant 4
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | G7; MUTSH5; NG23; POF13 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC309519 representing NM_172166.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCCTCCTTAGGAGCGAACCCAAGGAGGACACCGCAGGGACCGAGACCTGGGGCGGCCTCCTCCGGC TTCCCCAGCCCGGCCCCAGTGCCGGGCCCCAGGGAGGCCGAGGAGGAGGAAGTCGAGGAGGAGGAGGAG CTGGCCGAGATCCATCTGTGTGTGCTGTGGAATTCAGGATACTTGGGCATTGCCTACTATGATACTAGT GACTCCACTATCCACTTCATGCCAGATGCCCCAGACCACGAGAGCCTCAAGCTTCTCCAGAGAGTTCTG GATGAGATCAATCCCCAGTCTGTTGTTACGAGTGCCAAACAGGATGAGAATATGACTCGATTTCTGGGA AAGCTTGCCTCCCAGGAGCACAGAGAGCCTAAAAGACCTGAAATCATATTTTTGCCAAGTGTGGATTTT GGTCTGGAGATAAGCAAACAACGCCTCCTTTCTGGAAACTACTCCTTCATCCCAGACGCCATGACTGCC ACTGAGAAAATCCTCTTCCTCTCTTCCATTATTCCCTTTGACTGCCTCCTCACAGTTCGAGCACTTGGA GGGCTGCTGAAGTTCCTGGGTCGAAGAAGAATCGGGGTTGAACTGGAAGACTATAATGTCAGCGTCCCC ATCCTGGGCTTTAAGAAATTTATGTTGACTCATCTGGTGAACATAGATCAAGACACTTACAGTGTTCTA CAGATTTTTAAGAGTGAGTCTCACCCCTCAGTGTACAAAGTGGCCAGTGGACTGAAGGAGGGGCTCAGC CTCTTTGGAATCCTCAACAGATGCCACTGTAAGTGGGGAGAGAAGCTGCTCAGGCTATGGTTCACACGT CCGACTCATGACCTGGGGGAGCTCAGTTCTCGTCTGGACGTCATTCAGTTTTTTCTGCTGCCCCAGAAT CTGGACATGGCTCAGATGCTGCATCGGCTCCTGGGTCACATCAAGAACGTGCCTCTGATTCTGAAACGC ATGAAGTTGTCCCACACCAAGGTCAGCGACTGGCAGGTTCTCTACAAGACTGTGTACAGTGCCCTGGGC CTGAGGGATGCCTGCCGCTCCCTGCCGCAGTCCATCCAGCTCTTTCGGGACATTGCCCAAGAGTTCTCT GATGACCTGCACCATATCGCCAGCCTCATTGGGAAAGTAGTGGACTTTGAGGGCAGCCTTGCTGAAAAT CGCTTCACAGTCCTCCCCAACATAGATCCTGAAATTGATGAGAAAAAGCGAAGACTGATGGGACTTCCC AGTTTCCTTACTGAGGTTGCCCGCAAGGAGCTGGAGAATCTGGACTCCCGTATTCCTTCATGCAGTGTC ATCTACATCCCTCTGATTGGCTTCCTTCTTTCTATTCCCCGCCTGCCTTCCATGGTAGAGGCCAGTGAC TTTGAGATTAATGGACTGGACTTCATGTTTCTCTCAGAGGAGAAGCTGCACTATCGTAGTGCCCGAACC AAGGAGCTGGATGCATTGCTGGGGGACCTGCACTGCGAGATCCGGGACCAGGAGACGCTGCTGATGTAC CAGCTACAGTGCCAGGTGCTGGCACGAGCAGCTGTCTTAACCCGAGTATTGGACCTTGCCTCCCGCCTG GACGTCCTGCTGGCTCTTGCCAGTGCTGCCCGGGACTATGGCTACTCAAGGCCGCGTTACTCCCCACAA GTCCTTGGGGTACGAATCCAGAATGGCAGACATCCTCTGATGGAACTCTGTGCCCGAACCTTTGTGCCC AACTCCACAGAATGTGGTGGGGACAAAGGGAGGGTCAAAGTCATCACTGGACCCAACTCATCAGGGAAG AGCATATACCTCAAACAGGTAGGCTTGATCACATTCATGGCCCTGGTAGGCAGCTTTGTGCCAGCAGAG GAGGCCGAAATTGGGGCAGTAGACGCCATCTTCACACGAATTCATAGCTGCGAATCCATCTCCCTTGGC CTCTCCACCTTCATGATCGACCTCAACCAGGTGGCGAAAGCAGTGAACAATGCCACTGCACAGTCGCTG GTCCTTATTGATGAATTTGGAAAGGGAACCAACACGGTGGATGGGCTCGCGCTTCTGGCCGCTGTGCTC CGACACTGGCTGGCACGTGGACCCACATGCCCCCACATCTTTGTGGCCACCAACTTTCTGAGCCTTGTT CAGCTACAACTGCTGCCACAAGGGCCCCTGGTGCAGTATTTGACCATGGAGACCTGTGAGGATGGCAAC GATCTTGTCTTCTTCTATCAGGTTTGCGAAGGTGTTGCGAAGGCCAGCCATGCCTCCCACACAGCTGCC CAGGCTGGGCTTCCTGACAAGCTTGTGGCTCGTGGCAAGGAGGTCTCAGACTTGATCCGCAGTGGAAAA CCCATCAAGCCTGTCAAGGATTTGCTAAAGAAGAACCAAATGGAAAATTGCCAGACATTAGTGGATAAG TTTATGAAACTGGATTTGGAAGATCCTAACCTGGACTTGAACGTTTTCATGAGCCAGGAAGTGCTGCCT GCTGCCACCAGCATCCTCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_172166 |
| Insert Size | 2505 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_172166.3 |
| RefSeq Size | 2787 bp |
| RefSeq ORF | 2505 bp |
| Locus ID | 4439 |
| UniProt ID | O43196 |
| Protein Families | Druggable Genome |
| MW | 92.9 kDa |
| Gene Summary | This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene. [provided by RefSeq, Feb 2011] Transcript Variant: This variant (4) uses alternate in-frame splice sites in both the central and 3' coding regions, compared to variant 1, resulting in an isoform (c) that is longer than isoform a. Both variants 3 and 4 encode the same isoform. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212608 | MSH5 (Myc-DDK-tagged)-Human mutS homolog 5 (E. coli) (MSH5), transcript variant 4 |
CNY 4,180.00 |
|
| RC212608L3 | Lenti ORF clone of Human mutS homolog 5 (E. coli) (MSH5), transcript variant 4, Myc-DDK-tagged |
CNY 8,512.00 |
|
| RC212608L4 | Lenti ORF clone of Human mutS homolog 5 (E. coli) (MSH5), transcript variant 4, mGFP tagged |
CNY 5,890.00 |
|
| RG212608 | MSH5 (tGFP-tagged) - Human mutS homolog 5 (E. coli) (MSH5), transcript variant 4 |
CNY 4,370.00 |
