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Collagen IV alpha 6 (COL4A6) (NM_033641) Human Untagged Clone
CAT＃: SC309480
COL4A6 (untagged)-Human collagen, type IV, alpha 6 (COL4A6), transcript variant B
CNY 32,490.00
货期*
详询
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CXDELq22.3; DELXq22.3; DFNX6 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_033641, the custom clone sequence may differ by one or more nucleotides
ATGCACCCTGGGTTGTGGCTGCTCCTGGTTACGTTGTGCCTGACCGAGGAACTGGCAGCA GCGGGAGAGAAGTCTTATGGAAAGCCATGTGGGGGCCAGGACTGCAGTGGGAGCTGTCAG TGTTTTCCTGAGAAAGGAGCGAGAGGACGACCTGGACCAATTGGAATTCAAGGCCCAACA GGTCCTCAAGGATTCACTGGCTCTACTGGTTTATCGGGATTGAAAGGAGAAAGGGGTTTC CCAGGCCTTCTGGGACCTTATGGACCAAAAGGAGATAAGGGTCCCATGGGAGTTCCTGGC TTTCTTGGCATCAATGGGATTCCGGGCCACCCTGGACAACCAGGCCCCAGAGGCCCACCT GGTCTGGATGGCTGTAATGGAACTCAAGGAGCTGTTGGATTTCCAGGCCCTGATGGCTAT CCTGGGCTTCTCGGACCACCCGGGCTTCCTGGTCAGAAAGGATCAAAAGGTGACCCTGTC CTTGCTCCAGGTAGTTTCAAAGGAATGAAGGGGGATCCTGGGCTGCCTGGACTGGATGGA ATCACTGGCCCACAAGGAGCACCCGGATTTCCTGGAGCTGTAGGACCTGCAGGACCACCA GGATTACAAGGTCCTCCAGGGCCTCCTGGTCCTCTTGGTCCTGATGGGAATATGGGGCTA GGTTTTCAAGGAGAGAAAGGAGTCAAGGGGGATGTTGGCCTCCCTGGCCCAGCAGGACCT CCACCATCTACTGGAGAGCTGGAATTCATGGGATTCCCCAAAGGGAAGAAAGGATCCAAG GGTGAACCAGGGCCTAAGGGTTTTCCAGGCATAAGTGGCCCTCCAGGCTTCCCGGGCCTT GGAACTACTGGAGAAAAGGGAGAAAAGGGAGAAAAGGGAATCCCTGGTTTGCCAGGACCT AGGGGTCCCATGGGTTCAGAAGGAGTCCAAGGCCCTCCAGGGCAACAGGGCAAGAAAGGG ACCCTGGGATTTCCTGGGCTTAATGGATTCCAAGGAATTGAGGGTCAAAAGGGTGACATT GGCCTGCCAGGCCCAGATGTTTTCATCGATATAGATGGTGCTGTGATCTCAGGTAATCCT GGAGATCCTGGTGTACCTGGCCTCCCAGGCCTTAAAGGAGATGAAGGCATCCAAGGCCTA CGTGGCCCTTCTGGTGTCCCTGGATTGCCAGCATTATCAGGTGTCCCAGGAGCCCTAGGG CCTCAGGGATTTCCAGGGCTGAAGGGGGACCAAGGAAACCCAGGCCGTACCACAATTGGA GCAGCTGGCCTCCCTGGCAGAGATGGTTTGCCAGGCCCACCAGGTCCACCAGGCCCACCT AGTCCAGAATTTGAGACTGAAACTCTACACAACAAAGAGTCAGGGTTCCCTGGTCTCCGA GGAGAACAAGGTCCAAAAGGAAACCTAGGCCTCAAAGGAATAAAAGGAGACTCAGGTTTC TGTGCTTGTGACGGTGGTGTTCCCAACACTGGACCACCCGGGGAACCAGGCCCACCTGGT CCATGGGGTCTCATAGGCCTTCCAGGCCTTAAAGGAGCCAGAGGAGATCGAGGCTCTGGG GGTGCACAGGGCCCAGCAGGGGCTCCAGGCTTAGTTGGGCCTCTGGGTCCTTCAGGACCC AAAGGAAAGAAGGGGGAACCAATTCTCAGTACAATCCAAGGAATGCCAGGAGATCGGGGT GATTCTGGCTCCCAGGGCTTCCGTGGTGTAATAGGAGAACCAGGCAAGGACGGAGTACCA GGTTTACCAGGTCTGCCAGGCCTTCCGGGTGATGGTGGACAGGGCTTCCCAGGTGAAAAG GGGTTACCTGGACTTCCTGGTGAAAAAGGCCATCCTGGTCCACCTGGCCTCCCAGGAAAT GGGTTACCAGGACTTCCTGGACCCCGTGGGCTTCCTGGAGATAAAGGCAAGGATGGATTA CCGGGACAACAAGGCCTTCCCGGATCTAAGGGAATCACCCTGCCCTGTATTATTCCTGGG TCATACGGTCCATCAGGATTTCCAGGCACTCCCGGATTCCCAGGCCCTAAAGGGTCTCGA GGCCTCCCTGGGACCCCAGGCCAGCCTGGGTCAAGTGGAAGTAAAGGAGAGCCAGGGAGT CCAGGATTGGTTCATCTTCCTGAATTACCAGGATTTCCTGGACCTCGTGGGGAGAAGGGC TTGCCTGGGTTTCCTGGGCTCCCTGGAAAAGATGGCTTGCCTGGGATGATTGGCAGTCCA GGCTTACCTGGTTCCAAGGGAGCCACTGGTGACATCTTTGGTGCTGAAAATGGTGCTCCG GGGGAACAAGGCCTACAAGGATTAACAGGGCACAAAGGATTTCTTGGAGACTCTGGCCTT CCAGGACTCAAGGGTGTGCACGGGAAGCCTGGCTTACTAGGCCCCAAAGGTGAGCGGGGC AGCCCTGGGACACCAGGACAGGTGGGACAGCCAGGCACCCCAGGATCTAGTGGTCCATAT GGCATCAAGGGCAAATCTGGGCTCCCAGGAGCACCAGGCTTCCCAGGCATCTCAGGACAT CCTGGAAAGAAAGGAACAAGAGGCAAGAAAGGTCCTCCTGGATCAATTGTAAAGAAAGGG CTGCCAGGGCTAAAAGGCCTTCCTGGAAATCCAGGCCTAGTAGGACTGAAAGGAAGCCCA GGCTCTCCAGGGGTCGCTGGGTTGCCAGCCCTCTCTGGACCCAAGGGAGAGAAGGGGTCT GTTGGATTCGTAGGTTTTCCAGGAATACCAGGTCTGCCTGGTATTCCTGGAACAAGAGGA TTAAAAGGAATTCCAGGATCAACTGGAAAAATGGGACCATCTGGACGTGCTGGTACTCCT GGTGAAAAGGGAGACAGAGGCAATCCGGGGCCAGTCGGAATACCTAGTCCAAGACGTCCA ATGTCAAACCTTTGGCTCAAAGGAGACAAAGGCTCTCAAGGCTCAGCCGGATCCAATGGA TTTCCTGGGCCAAGAGGTGACAAAGGAGAGGCTGGTCGACCTGGACCACCAGGCCTACCT GGAGCTCCTGGCCTCCCAGGCATTATCAAAGGAGTTAGTGGAAAGCCAGGGCCCCCTGGC TTCATGGGAATCCGGGGCTTACCTGGCCTGAAGGGGTCCTCTGGGATCACAGGTTTCCCA GGAATGCCAGGAGAAAGTGGTTCACAAGGTATCAGAGGGTCGCCTGGACTCCCAGGAGCA TCTGGTCTCCCAGGCCTGAAAGGAGACAACGGCCAGACAGTTGAAATTTCCGGTAGCCCA GGACCCAAGGGACAGCCTGGCGAATCTGGTTTTAAAGGCACAAAAGGAAGAGATGGACTA ATAGGCAATATAGGCTTCCCTGGAAACAAAGGTGAAGATGGAAAAGTTGGTGTTTCTGGA GATGTTGGCCTTCCTGGAGCTCCAGGATTTCCAGGAGTTGCCGGCATGAGAGGAGAACCA GGACTTCCAGGTTCTTCTGGTCACCAAGGGGCAATTGGGCCTCTAGGATCCCCCGGATTA ATAGGACCCAAAGGCTTCCCTGGATTTCCTGGTTTACATGGACTGAATGGGCTTCCGGGC ACCAAGGGTACCCATGGCACTCCAGGACCTAGTATCACCGGTGTGCCTGGGCCTGCTGGT CTCCCTGGACCCAAAGGAGAAAAAGGATATCCAGGAATTGGCATCGGAGCTCCAGGGAAG CCGGGCCTGAGAGGGCAAAAAGGTGATCGAGGTTTCCCAGGTCTCCAGGGCCCTGCTGGT CTCCCCGGTGCCCCAGGCATCTCCTTGCCCTCACTCATAGCAGGACAGCCTGGTGACCCC GGGCGACCAGGCCTAGATGGAGAACGAGGCCGCCCAGGCCCCGCTGGACCCCCAGGTCCC CCTGGGCCATCCTCGAATCAAGGCGACACCGGAGACCCTGGCTTCCCTGGAATTCCTGGA CCTAAAGGGCCTAAGGGAGACCAAGGAATTCCAGGTTTTTCTGGCCTCCCTGGAGAGCTA GGACTGAAAGGCATGAGAGGTGAGCCTGGCTTCATGGGGACTCCAGGCAAGGTTGGGCCA CCTGGAGACCCAGGATTTCCCGGAATGAAGGGGAAGGCAGGGCCAAGAGGCTCTTCTGGC CTCCAAGGTGATCCTGGACAAACACCAACTGCAGAAGCTGTCCAGGTTCCTCCTGGACCC TTGGGTCTACCAGGGATCGATGGCATCCCTGGCCTCACTGGGGACCCTGGGGCTCAAGGC CCTGTAGGCCTACAAGGCTCCAAAGGTTTACCTGGCATCCCCGGTAAAGATGGCCCCAGT GGGCTCCCAGGCCCACCTGGGGCTCTTGGTGATCCTGGTCTGCCTGGACTGCAAGGCCCT CCAGGATTTGAAGGAGCTCCAGGGCAGCAAGGCCCCTTCGGGATGCCTGGAATGCCTGGC CAGAGCATGAGAGTGGGCTACACGTTGGTAAAGCACAGCCAGTCGGAACAGGTGCCCCCG TGTCCCATCGGGATGAGCCAGCTGTGGGTGGGGTACAGCTTACTGTTTGTGGAGGGGCAA GAGAAAGCCCACAACCAGGACCTGGGCTTTGCTGGCTCCTGTCTGCCCCGCTTCAGCACC ATGCCCTTCATCTACTGCAACATCAACGAGGTGTGCCACTATGCCAGGCGCAATGATAAA TCTTACTGGCTCTCCACTACCGCCCCTATCCCCATGATGCCCGTCAGCCAGACCCAGATT CCCCAGTACATCAGCCGCTGCTCTGTGTGTGAGGCACCCTCGCAAGCCATTGCTGTGCAC AGCCAGGACATCACCATCCCGCAGTGCCCCCTGGGCTGGCGCAGCCTCTGGATTGGGTAC TCTTTCCTCATGCACACTGCCGCTGGTGCCGAGGGTGGAGGCCAGTCCCTGGTCTCACCT GGCTCCTGCCTAGAGGACTTTCGGGCCACTCCTTTCATCGAATGCAGTGGTGCCCGAGGC ACCTGCCACTACTTTGCAAACAAGTACAGTTTCTGGTTGACCACAGTGGAGGAGAGGCAG CAGTTTGGGGAGTTGCCTGTGTCTGAAACGCTGAAAGCTGGGCAGCTCCACACTCGAGTC AGTCGCTGCCAGGTGTGTATGAAAAGCCTGTAG |
| Restriction Sites | Please inquire |
| ACCN | NM_033641 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_033641.1, NP_378667.1 |
| RefSeq Size | 6689 bp |
| RefSeq ORF | 5073 bp |
| Locus ID | 1288 |
| UniProt ID | Q14031 |
| Domains | C4, Collagen |
| Protein Pathways | ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer |
| Gene Summary | This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013] Transcript Variant: This variant (B) utilizes the same 5' exon as variant 3 (exon 1B) but lacks several alternate in-frame exons. The resulting protein (isoform B) is shorter compared to isoform 3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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