United States
Germany
Japan
United Kingdom
China
CBFA2T3 (NM_175931) Human Untagged Clone
CAT＃: SC309467
CBFA2T3 (untagged)-Human core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (CBFA2T3), transcript variant 2
CNY 9,120.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ETO2; MTG16; MTGR2; RUNX1T3; ZMYND4 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC309467 representing NM_175931.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGCCGGACTCCCCAGCGGAGGTGAAGACGCAGCCCCGGTCCACACCCCCCAGCATGCCGCCCCCACCG CCTGCCGCATCCCAGGGGGCCACACGCCCCCCCTCCTTCACGCCACACACACTGATGAACGGCAGCAGC CACTCACCAACAGCCATCAATGGTGCACCGTGCACACCCAACGGCTTCAGCAATGGCCCGGCCACCTCG TCCACAGCCTCCTTGTCCACACAGCACCTGCCCCCAGCCTGCGGGGCCCGGCAGCTCAGCAAGCTCAAG CGCTTCCTCACCACACTGCAGCAGTTTGGCAGCGACATCTCCCCAGAGATTGGGGAGCGCGTGCGCACA CTGGTGCTGGGCCTGGTGAACTCGACATTGACGATCGAGGAGTTTCATTCCAAGCTTCAGGAGGCCACC AACTTCCCTCTGCGGCCGTTTGTCATTCCCTTCCTGAAGGCAAACCTGCCCTTGCTGCAGCGGGAGCTC CTGCACTGTGCACGCCTGGCCAAGCAGACGCCCGCCCAGTACTTGGCCCAGCATGAGCAGCTCCTGCTG GACGCCAGCGCCTCCTCCCCCATCGACTCCTCAGAGCTGCTACTGGAAGTCAACGAGAACGGCAAGAGG AGGACGCCCGACAGGACCAAAGAGAACGGGTCAGACCGCGACCCGCTGCACCCCGAGCACCTCAGCAAA CGGCCATGCACCCTGAACCCTGCCCAGCGCTACAGCCCCAGCAACGGGCCACCGCAGCCCACACCGCCG CCGCACTACCGCCTGGAGGACATAGCCATGGCCCACCACTTCCGAGATGCCTACCGCCACCCAGACCCC CGGGAGCTACGAGAGCGCCATCGGCCGCTTGTGGTGCCTGGGTCCCGGCAGGAAGAAGTGATCGACCAC AAGCTCACAGAGCGTGAGTGGGCAGAAGAGTGGAAGCACCTCAACAACCTCCTGAACTGCATCATGGAC ATGGTGGAGAAGACGCGGCGCTCGCTCACGGTGCTGCGCAGGTGCCAGGAGGCCGACCGCGAGGAGCTC AACCACTGGGCGCGGCGCTACAGCGACGCCGAGGACACAAAGAAGGGCCCCGCTCCCGCCGCGGCCCGG CCCCGCAGCAGCTCCGCCGGTCCCGAAGGGCCTCAGCTAGACGTGCCTCGCGAGTTCCTGCCGAGGACC CTCACCGGCTACGTGCCTGAGGACATCTGGAGGAAGGCTGAAGAGGCCGTGAATGAGGTGAAGCGGCAG GCCATGTCGGAGCTGCAGAAAGCCGTGTCGGACGCGGAGCGCAAAGCGCACGAGCTCATCACCACGGAG CGTGCCAAGATGGAGCGGGCCCTGGCCGAGGCGAAGCGGCAGGCCTCCGAGGACGCCCTGACGGTCATC AACCAGCAGGAGGACTCCAGCGAGAGCTGCTGGAACTGCGGGCGGAAAGCCAGTGAGACGTGCAGCGGC TGCAACGCGGCACGCTACTGCGGGTCCTTCTGCCAGCATCGGGACTGGGAGAAGCATCACCACGTGTGT GGCCAGAGCCTGCAGGGCCCCACAGCCGTGGTGGCCGACCCGGTGCCTGGACCGCCCGAAGCCGCCCAC AGCCTGGGCCCCTCCCTGCCTGTGGGTGCTGCCAGCCCCAGCGAAGCCGGCTCTGCGGGGCCTTCTCGC CCCGGCTCCCCCAGCCCACCTGGCCCACTGGACACCGTGCCCCGCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_175931 |
| Insert Size | 1704 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_175931.2 |
| RefSeq Size | 4038 bp |
| RefSeq ORF | 1704 bp |
| Locus ID | 863 |
| UniProt ID | O75081 |
| Protein Families | Transcription Factors |
| MW | 62.4 kDa |
| Gene Summary | This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010] Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate in-frame coding exon, compared to variant 1. These differences cause translation initiation at a downstream start codon and result in an isoform (2) that lacks an internal segment and has a shorter N-terminus, compared to isoform 1. Variant 2 is also known as MTG16b. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223730 | CBFA2T3 (Myc-DDK-tagged)-Human core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (CBFA2T3), transcript variant 2 |
CNY 4,224.00 |
|
| RC223730L3 | Lenti-ORF clone of CBFA2T3 (Myc-DDK-tagged)-Human core-binding factor, runt domain, alpha subunit 2; translocated to, 3 (CBFA2T3), transcript variant 2 |
CNY 6,940.00 |
|
| RC223730L4 | Lenti-ORF clone of CBFA2T3 (mGFP-tagged)-Human core-binding factor, runt domain, alpha subunit 2; translocated to, 3 (CBFA2T3), transcript variant 2 |
CNY 6,940.00 |
|
| RG223730 | CBFA2T3 (tGFP-tagged) - Human core-binding factor, runt domain, alpha subunit 2; translocated to, 3 (CBFA2T3), transcript variant 2 |
CNY 5,510.00 |
其它CBFA2T3产品
