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KCNQ2 (NM_172107) Human Untagged Clone
CAT＃: SC309163
KCNQ2 (untagged)-Human potassium voltage-gated channel, KQT-like subfamily, member 2 (KCNQ2), transcript variant 1
CNY 6,392.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BFNC; DEE7; EBN; EBN1; ENB1; HNSPC; KCNA11; KV7.2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_172107 edited
CCCCGCTGAGCCTGAGCCCGACCCGGGGCGCCTCCCGCCAGGCACCATGGTGCAGAAGTC GCGCAACGGCGGCGTATACCCCGGCCCGAGCGGGGAGAAGAAGCTGAAGGTGGGCTTCGT GGGGCTGGACCCCGGCGCGCCCGACTCCACCCGGGACGGGGCGCTGCTGATCGCCGGCTC CGAGGCCCCCAAGCGCGGCAGCATCCTCAGCAAACCTCGCGCGGGCGGCGCGGGCGCCGG GAAGCCCCCCAAGCGCAACGCCTTCTACCGCAAGCTGCAGAATTTCCTCTACAACGTGCT GGAGCGGCCGCGCGGCTGGGCGTTCATCTACCACGCCTACGTGTTCCTCCTGGTTTTCTC CTGCCTCGTGCTGTCTGTGTTTTCCACCATCAAGGAGTATGAGAAGAGCTCGGAGGGGGC CCTCTACATCCTGGAAATCGTGACTATCGTGGTGTTTGGCGTGGAGTACTTCGTGCGGAT CTGGGCCGCAGGCTGCTGCTGCCGGTACCGTGGCTGGAGGGGGCGGCTCAAGTTTGCCCG GAAACCGTTCTGTGTGATTGACATCATGGTGCTCATCGCCTCCATTGCGGTGCTGGCCGC CGGCTCCCAGGGCAACGTCTTTGCCACATCTGCGCTCCGGAGCCTGCGCTTCCTGCAGAT TCTGCGGATGATCCGCATGGACCGGCGGGGAGGCACCTGGAAGCTGCTGGGCTCTGTGGT CTATGCCCACAGCAAGGAGCTGGTCACTGCCTGGTACATCGGCTTCCTTTGTCTCATCCT GGCCTCGTTCCTGGTGTACTTGGCAGAGAAGGGGGAGAACGACCACTTTGACACCTACGC GGATGCACTCTGGTGGGGCCTGATCACGCTGACCACCATTGGCTACGGGGACAAGTACCC CCAGACCTGGAACGGCAGGCTCCTTGCGGCAACCTTCACCCTCATCGGTGTCTCCTTCTT CGCGCTGCCTGCAGGCATCTTGGGGTCTGGGTTTGCCCTGAAGGTTCAGGAGCAGCACAG GCAGAAGCACTTTGAGAAGAGGCGGAACCCGGCAGCAGGCCTGATCCAGTCGGCCTGGAG ATTCTACGCCACCAACCTCTCGCGCACAGACCTGCACTCCACGTGGCAGTACTACGAGCG AACGGTCACCGTGCCCATGTACAGTTCGCAAACTCAAACCTACGGGGCCTCCAGACTTAT CCCCCCGCTGAACCAGCTGGAGCTGCTGAGGAACCTCAAGAGTAAATCTGGACTCGCTTT CAGGAAGGACCCCCCGCCGGAGCCGTCTCCAAGTAAAGGCAGCCCGTGCAGAGGGCCCCT GTGTGGATGCTGCCCCGGACGCTCTAGCCAGAAGGTCAGTTTGAAAGATCGTGTCTTCTC CAGCCCCCGAGGCGTGGCTGCCAAGGGGAAGGGGTCCCCGCAGGCCCAGACTGTGAGGCG GTCACCCAGCGCCGACCAGAGCCTCGAGGACAGCCCCAGCAAGGTGCCCAAGAGCTGGAG CTTCGGGGACCGCAGCCGGGCACGCCAGGCTTTCCGCATCAAGGGTGCCGCGTCACGGCA GAACTCAGAAGAAGCAAGCCTCCCCGGAGAGGACATTGTGGATGACAAGAGCTGCCCCTG CGAGTTTGTGACCGAGGACCTGACCCCGGGCCTCAAAGTCAGCATCAGAGCCGTGTGTGT CATGCGGTTCCTGGTGTCCAAGCGGAAGTTCAAGGAGAGCCTGCGGCCCTACGACGTGAT GGACGTCATCGAGCAGTACTCAGCCGGCCACCTGGACATGCTGTCCCGAATTAAGAGCCT GCAGTCCAGAGTGGACCAGATCGTGGGGCGGGGCCCAGCGATCACGGACAAGGACCGCAC CAAGGGCCCGGCCGAGGCGGAGCTGCCCGAGGACCCCAGCATGATGGGACGGCTCGGGAA GGTGGAGAAGCAGGTCTTGTCCATGGAGAAGAAGCTGGACTTCCTGGTGAATATCTACAT GCAGCGGATGGGCATCCCCCCGACAGAGACCGAGGCCTACTTTGGGGCCAAAGAGCCGGA GCCGGCGCCGCCGTACCACAGCCCGGAAGACAGCCGGGAGCATGTCGACAGGCACGGCTG CATTGTCAAGATCGTGCGCTCCAGCAGCTCCACGGGCCAGAAGAACTTCTCGGCGCCCCC GGCCGCGCCCCCTGTCCAGTGTCCGCCCTCCACCTCCTGGCAGCCACAGAGCCACCCGCG CCAGGGCCACGGCACCTCCCCCGTGGGGGACCACGGCTCCCTGGTGCGCATCCCGCCGCC GCCTGCCCACGAGCGGTCGCTGTCCGCCTACGGCGGGGGCAACCGCGCCAGCATGGAGTT CCTGCGGCAGGAGGACACCCCGGGCTGCAGGCCCCCCGAGGGGAACCTGCGGGACAGCGA CACGTCCATCTCCATCCCGTCCGTGGACCACGAGGAGCTGGAGCGTTCCTTCAGCGGCTT CAGCATCTCCCAGTCCAAGGAGAACCTGGATGCTCTCAACAGCTGCTACGCGGCCGTGGC GCCTTGTGCCAAAGTCAGGCCCTACATTGCGGAGGGAGAGTCAGACACCGACTCCGACCT CTGTACCCCGTGCGGGCCCCCGCCACGCTCGGCCACCGGCGAGGGTCCCTTTGGTGACGT GGGCTGGGCCGGGCCCAGGAAGTGA >OriGene 5' read for NM_172107 unedited
GTTAAATTTGTATACCACTCATATAGGGCGGCCGCGAATTCGCACGAGCCCCGCTGAGCC TGAGCCCGACCCGGGGCGCCTCCCGCCAGGCACCATGGTGCAGAAGTCGCGCAACGGCGG CGTATACCCCGGCCCGAGCGGGGAGAAGAAGCTGAAGGTGGGCTTCGTGGGGCTGGACCC CGGCGCGCCCGACTCCACCCGGGACGGGGCGCTGCTGATCGCCGGCTCCGAGGCCCCCAA GCGCGGCAGCATCCTCAGCAAACCTCGCGCGGGCGGCGCGGGCGCCGGGAAGCCCCCCAA GCGCAACGCCTTCTACCGCAAGCTGCAGAATTTCCTCTACAACGTGCTGGAGCGGCCGCG CGGCTGGGCGTTCATCTACCACGCCTACGTGTTCCTCCTGGTTTTCTCCTGCCTCGTGCT GTCTGTGTTTTCCACCATCAAGGAGTATGAGAAGAGCTCGGAGGGGGCCCTCTACATCCT GGAAATCGTGACTATCGTGGTGTTTGGCGTGGAGTACTTCGTGCGGATCTGGGCCGCAGG CTGCTGCTGCCGGTACCGTGGCTGGAGGGGGCGGCTCAAGTTTGCCCGGAAACCGTTCTG TGTGATTGACATCATGGTGCTCATCGCCTCCATTGCGGTGCTGGCCGCCGGCTCCCAGGG CAACGTCTTTGCCACATCTGCGCTCCGGAGCCTGCGCTTCCTGCAGATTCTGCGGATGAT CCGCATGGACCGGCGGGGAGGCACCTGGAAGCTGCTGGGCTCTGTGGTCTATGCCCACAG CAAGGAGCTGGTCACTGCCTGGTACATCGGCTTCCTTTGTCTCAC >OriGene 3' read for NM_172107 unedited
CATGGGGATGGCACTTCCGGCCAGGAAGCACTGGGGAGGGTCACAGGGTGCCCCCGGGAT CTGTTCAGAAACAGCTATGACCGCGGCCGCAATCTAGATCACTTCCTGGGCCCGGCCCAG CCCACGTCACCAAAGGGACCCTCGCCGGTGGCCGAGCGTGGCGGGGGCCCGCACGGGGTA CAGAGGTCGGAGTCGGTGTCTGACTCTCCCTCCGCAATGTAGGGCCTGACTTTGGCACAA GGCGCCACGGCCGCGTAGCAGCTGTTGAGAGCATCCAGGTTCTCCTTGGACTGGGAGATG CTGAAGCCGCTGAAGGAACGCTCCAGCTCCTCGTGGTCCACGGACGGGATGGAGATGGAC GTGTCGCTGTCCCGCAGGTTCCCCTCGGGGGGCCTGCAGCCCGGGGTGTCCTCCTGCCGC AGGAACTCCATGCTGGCGCGGTTGCCCCCGCCGTAGGCGGACAGCGACCGCTCGTGGGCA GGCGGCGGCGGGATGCGCACCAGGGAGCCGTGGTCCCCCACGGNGGAGGTGCCGTGGCCC TGGCGCGGGTGGCTCTGTGGCTGCCAGGAGGTGGAGGGCGGACACTGGACAGGGGGCGCG GCCGGNGGCGCCGAGAAGTTCTTCTGGCCCGTGGAGCTGCTGGAGCGCACGATCTTGACA ATGCAGCCGTGCCTGTCGACATGCTCCCGGCTGTCTTCCGGGCTGTGGTACGGCGGCGCC GGCTCGGGCTCTTTGGCCCCAAAGTAGGCCTCGGTCTCTGTCGGGGGGATGCCCATCCGC TGCATGTANATATTCACCAGGAGTCCAGCTCTTTCTCATGGACAAGACTGCTTCTA |
| Restriction Sites | Please inquire |
| ACCN | NM_172107 |
| Insert Size | 2700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_172107.2, NP_742105.1 |
| RefSeq Size | 3251 bp |
| RefSeq ORF | 2619 bp |
| Locus ID | 3785 |
| UniProt ID | O43526 |
| Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
| Gene Summary | The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212932 | KCNQ2 (Myc-DDK-tagged)-Human potassium voltage-gated channel, KQT-like subfamily, member 2 (KCNQ2), transcript variant 1 |
CNY 9,576.00 |
|
| RC212932L1 | Lenti ORF clone of Human potassium voltage-gated channel, KQT-like subfamily, member 2 (KCNQ2), transcript variant 1, Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC212932L2 | Lenti ORF clone of Human potassium voltage-gated channel, KQT-like subfamily, member 2 (KCNQ2), transcript variant 1, mGFP tagged |
CNY 11,976.00 |
|
| RC212932L3 | Lenti ORF clone of Human potassium voltage-gated channel, KQT-like subfamily, member 2 (KCNQ2), transcript variant 1, Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC212932L4 | Lenti ORF clone of Human potassium voltage-gated channel, KQT-like subfamily, member 2 (KCNQ2), transcript variant 1, mGFP tagged |
CNY 9,030.00 |
|
| RG212932 | KCNQ2 (tGFP-tagged) - Human potassium voltage-gated channel, KQT-like subfamily, member 2 (KCNQ2), transcript variant 1 |
CNY 11,176.00 |
