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EYA4 (NM_004100) Human Untagged Clone
CAT＃: SC308997
EYA4 (untagged)-Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 1
CNY 4,768.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CMD1J; DFNA10 |
| Vector | PCMV6-Neo |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_004100 edited
GGGAAAAGCCGGGGAGTGACGACTGCGGCGGCTGGGCGCGCTCTCTCATTTTCTTTTCTT CTCCTTTCCCCCCTGTCGCAGTCCGGAGTTTTGGCTCCTCTCCTTTCCTCCTCCCCCTCG GAGCCGGCTTCTCCCTCCGCCCCGCTTCTCCCCCGCTTGTGTACGCTATTTGTTGTGGGG TGGCCGAAGGGGATGTCCTGTTTTCACCAGAGGCACAGCGCGAAGGGGAAACTTCGACAC TGGAAGGAACGAGAATAAATACTTAATTACGGACGCACTGAACCGCGGCTGGGACAGACA CTTCGGGAACCCGAGGCGGACCGGGCGACGAGATAGTCATTTTTACTTGAAGGAAGCTGC TTCTACTTGGGAGTGGCAGGAGAAGTGAGAAAACCACATGGAAGACTCCCAGGATTTAAA TGAACAATCAGTAAAGAAAACGTGCACAGAATCAGATGTTTCACAATCTCAGAATTCCAG GTCTATGGAAATGCAGGACCTAGCAAGTCCTCATACTCTTGTTGGAGGTGGTGATACTCC AGGTAGCTCCAAACTGGAAAAATCTAATCTCAGCAGCACATCAGTTACTACAAATGGGAC AGGAGGGGAAAACATGACTGTTTTAAACACAGCAGACTGGTTGCTGAGTTGCAACACCCC CTCTTCTGCAACAATGTCTCTTCTTGCAGTCAAAACAGAGCCCTTGAACAGCAGTGAAAC CACAGCCACGACTGGAGATGGAGCGCTTGACACTTTTACTGGGTCAGTAATTACAAGTAG TGGCTACAGCCCCAGATCAGCACATCAGTATTCCCCACAGCTGTATCCTTCCAAGCCCTA TCCACACATTCTTTCTACACCAGCAGCTCAAACAATGTCTGCCTATGCAGGCCAGACTCA GTATTCGGGGATGCAGCAGCCAGCCGTCTACACAGCCTACTCACAGACAGGACAGCCCTA CAGCTTGCCCACTTACGATTTGGGTGTGATGTTGCCAGCCATCAAGACAGAGAGTGGACT TTCCCAAACTCAGTCCCCATTACAGAGTGGCTGCCTCAGTTACAGCCCAGGGTTCTCTAC CCCACAGCCAGGCCAGACACCTTATTCTTACCAAATGCCAGGTTCTAGTTTTGCACCATC ATCTACTATTTATGCAAATAATTCAGTTTCCAATTCAACAAATTTCAGTGGTTCACAACA GGATTATCCATCCTATACAGCCTTTGGCCAAAACCAGTATGCACAGTATTATTCAGCATC AACGTATGGAGCGTATATGACATCGAATAACACAGCCGATGGCACACCCTCTTCAACCTC TACTTATCAGTTGCAGGAATCTCTCCCAGGACTGACTAACCAACCAGGAGAGTTCGATAC CATGCAGAGTCCCTCCACACCCATCAAAGATCTTGATGAGAGAACCTGTAGGAGTTCTGG GTCAAAGTCCAGAGGAAGAGGCCGGAAAAATAATCCCTCCCCGCCTCCTGATAGTGACCT GGAGCGTGTGTTTGTCTGGGATTTGGATGAAACCATCATTGTTTTTCACTCACTGCTCAC CGGGTCTTATGCACAGAAGTATGGCAAGGATCCCCCCATGGCTGTAACCCTTGGACTCCG CATGGAAGAAATGATTTTTAATCTTGCTGATACTCATTTGTTTTTTAATGATTTAGAGGA GTGTGATCAAGTTCATATAGATGATGTTTCCTCTGATGATAATGGGCAGGACTTAAGTAC CTACAGTTTTGCAACTGATGGCTTCCATGCAGCTGCAAGTAGTGCAAACCTTTGTTTGCC AACAGGTGTAAGAGGAGGGGTTGACTGGATGAGGAAGTTGGCTTTTCGTTACAGAAGAGT AAAAGAATTATATAACACCTACAAGAACAACGTTGGAGGACTCCTTGGCCCTGCCAAGAG GGATGCCTGGCTACAGTTAAGGGCAGAGATTGAAGGTCTGACAGATTCCTGGCTAACAAA TGCACTTAAGTCTTTATCAATTATTAGCACTAGGAGTAACTGCATAAATGTCTTGGTAAC GACAACTCAACTGATCCCAGCACTTGCGAAGGTTCTACTCTATAGTTTAGGAGGTGCTTT CCCCATTGAGAATATTTACAGTGCAACTAAAATAGGAAAAGAAAGTTGCTTTGAACGAAT AATGCAAAGGTTTGGCAGAAAAGTAGTGTATGTTGTAATTGGGGATGGTGTAGAAGAAGA ACAGGCAGCAAAAAAGCACAACATGCCCTTCTGGAGGATATCCAGTCACTCAGACCTCCT GGCTCTCCACCAAGCACTGGAATTAGAGTATTTGTAACTGTGTTCTTTAGCCGGAGATCT ATTTTTTATATTTCAAGTACACTGAATTTTTATGTGTGATTCAATGCCTCTGGCTCTACA CATATAAATTGTCTTAATGGATGAAATCATATTTGGAATAAAAATTCCAGAATGAAGAAT TCAGATTGCTGAATGGAGTTAAACTTTAGTGCTACAGAAAAGAAACTCTATGGTCTTATA TTTACAACACTTTAATGGGTTTTTTAAAAATCTGTGGAGGTTGCTGGTACACACCAAATG AGTCCAAACTGGAATGAGCAGCTTTAGCAAAGAACTCTTACCCTGGCAAAGCAGCAACAC ACATGCTCCGTCTGACAAGGTGGTCAACAACATTCCTCAAAATGGGAGATCTTCTCAGCC CTGAGGTTTGAATCTGACTTTAGCCTACCTAACCCAGAAAATCTGAATTGGAATGCACTC AGACTGTATAAGGACAGTCCTATTTAGACATGTAATTTGTGTAAATTATTGATGAAAATA ATTTACTGTGACTTTATTAGCAGCTGACTTTCAAAGTGGATGCAATTTTTCTTTCTTTTG TTGGGGAGGGGAATGGGAGGGGAAATGGGAATATAATATTGTCTCTTTTTTAAGTTTGGC AAACAGAATGTTCATACTGATGTGTTGTGCCTTAAAGACAAGACAGCATTTGTGTGTTAC AATGTAACTTTGGTTAAAATCTCTGTAGATAATGAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_004100 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_004100.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004100.2, NP_004091.2 |
| RefSeq Size | 3077 bp |
| RefSeq ORF | 1920 bp |
| Locus ID | 2070 |
| UniProt ID | O95677 |
| Domains | Hydrolase |
| Protein Families | Druggable Genome, Phosphatase, Transcription Factors |
| Gene Summary | This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014] Transcript Variant: This variant (1) encodes isoform a, which is more abundant in adult brain. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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EYA4 Acts as a New Tumor Suppressor Gene in Colorectal Cancer
,Kim, SJ;Tae, CH;Hong, SN;Min, BH;Chang, DK;Rhee, PL;Kim, JJ;Kim, HC;Kim, DH;Kim, YH;,
Mol. Carcinog.
,PubMed ID 25620232
[EYA4]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211486 | EYA4 (Myc-DDK-tagged)-Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 1 |
CNY 4,760.00 |
|
| RC211486L3 | Lenti-ORF clone of EYA4 (Myc-DDK-tagged)-Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 1 |
CNY 5,890.00 |
|
| RC211486L4 | Lenti-ORF clone of EYA4 (mGFP-tagged)-Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 1 |
CNY 7,160.00 |
|
| RG211486 | EYA4 (tGFP-tagged) - Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 1 |
CNY 4,370.00 |
