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PIK3R5 (NM_014308) Human Untagged Clone
CAT＃: SC308923
PIK3R5 (untagged)-Human phosphoinositide-3-kinase, regulatory subunit 5 (PIK3R5), transcript variant 2
CNY 6,456.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | F730038I15Rik; FOAP-2; p101; P101-PI3K |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_014308 edited
ATGCAGCCAGGGGCCACGACATGCACGGAGGACCGCATCCAGCATGCCCTGGAACGCTGC CTGCATGGACTCAGCCTCAGCCGCCGCTCCACCTCCTGGTCAGCTGGGCTGTGTCTGAAC TGCTGGAGCCTSCAGGAGCTGGTCAGCAGGGACCCGGGCCACTTCCTTATCCTCCTTGAG CAGATCCTGCAGAAGACCCGAGAGGTCCAGGAGAAGGGCACCTACGACCTGCTCACCCCG CTGGCCCTGCTCTTCTATTCCACTGTTCTTTGTACACCACACTTCCCACCAGACTCGGAT CTCCTTCTGAAGGCAGCCAGCACCTACCACCGGTTCCTGACCTGGCCTGTTCCTTACTGC AGCATCTGCCAGGAGCTGCTCACCTTCATTGATGCTGAACTCAAGGCCCCAGGGATCTCC TACCAGAGACTGGTGAGGGCTGAGCAGGGCCTGCCCATCAGGAGTCACCGCAGCTCCACC GTCACCGTGCTGCTGCTGAACCCAGTGGAAGTGCAGGCCGAGTTCCTTGCTGTAGCCAAT AAGCTGAGTACGCCCGGACACTCGCCTCACAGTGCCTACACCACCCTGCTCCTGCACGCC TTCCAGGCCACCTTTGGGGCCCACTGTGACGTCCCGGGCCTGCACTGCAGGCTACAGGCC AAGACCCTGGCAGAGCTTGAGGACATCTTCACGGAGACCGCAGAGGCACAGGAGCTGGCA TCTGGCATCGGGGATGCTGCAGAGGCCCGGCGGTGGCTCAGGACCAAGCTGCAGGCGGTG GGAGAAAAAGCTGGCTTCCCTGGGGTGTTAGACACTGCAAAACCAGGGAAGCTCCACACC ATCCCCATCCCTGTCGCCAGGTGCTACACCTACAGCTGGAGCCAGGACAGCTTTGACATC CTGCAGGAAATCCTGCTCAAGGAACAGGAGCTGCTCCAGCCAGGGATCCTGGGAGATGAT GAAGAGGAGGAAGAGGAGGAGGAGGAGGTGGAGGAGGACTTGGAAACTGATGGGCACTGT GCCGAGAGAGATTCCCTGCTCTCCACCAGCTCTTTGGCGTCCCATGACTCCACCCTGTCC CTTGCATCCTCCCAGGCCTCAGGGCCGGCCCTCTCGCGCCATCTGCTGACTTCCTTTGTC TCAGGCCTCTCTGATGGCATGGACAGCGGCTACGTGGAGGACAGCGAGGAGAGCTCCTCC GAGTGGCCTTGGAGGCGTGGCAGCCAGGAACGCCGAGGCCACCGCAGGCCTGGGCAGAAG TTCATCAGGATCTATAAACTCTTCAAGAGCACCAGCCAGCTGGTACTGCGGAGGGACTCT CGGAGCCTGGAGGGCAGCTCGGACACGGCCCTGCCCCTGAGGCGGGCAGGGAGCCTCTGC AGCCCCCTGGACGAACCAGTATCACCCCCTTCCCGGGCCCAGCGCTCCCGCTCCCTGCCC CAGCCCAAACTCGGTACCCAGCTGCCCAGCTGGCTTCTGGCCCCTGCTTCACGCCCCCAG CGCCGCCGCCCCTTCCTGAGTGGAGATGAGGATCCCAAGGCTTCCACGCTACGTGTTGTG GTCTTTGGCTCCGATCGGATTTCAGGGAAGGTGGCTCGGGCGTACAGCAACCTTCGGCGG CTGGAGAACAATCGCCCACTCCTCACACGGTTCTTCAAACTTCAGTTCTTCTACGTGCCT GTGAAGCGAAGTCATGGGACCAGCCCTGGTGCCTGTCCACCCCCTCGGAGCCAGACGCCC TCACCCCCGACAGACTCCCCTAGGCACGCCAGCCCTGGAGAGCTGGGCACCACCCCATGG GAGGAGAGCACCAATGACATCTCCCACTACCTCGGCATGCTGGACCCCTGGTATGAGCGC AATGTACTGGGCCTCATGCACCTGCCCCCTGAAGTCCTGTGCCAGCAGTCCCTGAAGGCT GAAGCCCAGGCCCTGGAGGGCTCCCCAACCCAGCTGCCCATCCTGGCTGACATGCTACTC TACTACTGCCGCTTTGCCGCCAGACCGGTGCTGCTGCAAGTCTATCAGACCGAGCTGACC TTCATCACTGGGGAGAAGACGACAGAGATCTTCATCCACTCCTTGGAGCTGGGTCACTCC GCTGCCACACGTGCCATCAAGGCGTCAGGTCCTGGCAGCAAGCGGCTGGGCATCGATGGC GACCGGGAGGCTGTTCCTCTAACACTACAGATTATTTACAGCAAGGGGGCCATCAGTGGA CGAAGTCGCTGGAGCAACCTGGAGAAGGTCTGTACCTCCGTGAACCTCAACAAGGCCTGC CGGAAGCAGGAGGAGCTGGATTCCAGCATGGAGGCCCTGACGCTAAACCTGACAGAAGTG GTGAAAAGGCAGAACTCCAAATCCAAGAAGGGCTTTAACCAGATTAGCACATCGCAGATC AAAGTGGACAAGGTGCAGATCATCGGCTCCAACAGCTGCCCCTTTGCTGTGTGCCTGGAC CAGGATGAGAGAAAGATCCTGCAGAGTGTAGTCAGATGTGAGGTCTCACCGTGCTACAAG CCAGAGAAGAGCGACCTCTCCTCACCACCCCAGACGCCTCCTGACCTGCCGGCCCAGGCC GCACCTGATCTCTGCTCCCTTCTCTGCCTGCCCATCATGACTTTCAGTGGAGCTCTGCCC TAGTGTGGGCCCAGCGCCAGACTGGACAGAAGCCCTGGGGCAACCTCCTCGGCCACCCCT CCAGGACAGTCCCTCTCTGTGGAGAACTGAATGGCCCTGTGCAGAGCCATAGTCCCACTG TGGGTCCTGCAATGAGCAGGGGCTGGGAGTAGAGGGTTTCTGGGGCCTCAGGGTTCTGGG AAAGCAACAGCTATCAGAGAGAGAAGGGCCAGACCCCATAGCCTCTTAGATTCCTGGCAG TAGAAGGAGAAGGATGGGTAAATTGACCTCTGAAGTCCCTGACCATTAGCATGGTCTAGG ATCCTTTCTAGA >OriGene 5' read for NM_014308 unedited
GGTCAGATTTGTATACGACTCATATAGGCGGCCGCGNATTCATGCAGCCAGGGGCCACGA CATGCACGGAGGACCGCATCCAGCATGCCCTGGAACGCTGCCTGCATGGACTCAGCCTCA GCCGCCGCTCCACCTCCTGGTCAGCTGGGCTGTGTCTGAACTGCTGGAGCCTCCAGGAGC TGGTCAGCAGGGACCCGGGCCACTTCCTTATCCTCCTTGAGCAGATCCTGCAGAAGACCC GAGAGGTCCAGGAGAAGGGCACCTACGACCTGCTCACCCCGCTGGCCCTGCTCTTCTATT CCACTGTTCTTTGTACACCACACTTCCCACCAGACTCGGATCTCCTTCTGAAGGCAGCCA GCACCTACCACCGGTTCCTGACCTGGCCTGTTCCTTACTGCAGCATCTGCCAGGAGCTGC TCACCTTCATTGATGCTGAACTCAAGGCCCCAGGGATCTCCTACCAGAGACTGGTGAGGG CTGAGCAGGGCCTGCCCATCAGGAGTCACCGCAGCTCCACCGTCACCGTGCTGCTGCTGA ACCCAGTGGAAGTGCAGGCCGAGTTCCTTGCTGTAGCCAATAAGCTGAGTACGCCCGGAC ACTCGCCTCACAGTGCCTACACCACCCTGCTCCTGCACGCCTTCCAGGCCACCTTTGGGG CCCACTGTGACGTCCCGGGCCTGCACTGCAGGCTACAGGCCAAGACCCTGGCAGAGCTTG ANGACATCTTCACGGAGACCGCAGAGCACAGGAGCTGGCATCTGGCATCGGGGATGCTGC AGAGGCCCGGGCGTGGCTCANGACCAAGCTGCNAGCNGTGGGAGAAAAAGCTGGCTTTTC CTGGGGTGTAGACACTGCAAACCAGGAAGCTNCACACATCCCCTNCCTNNGTCGCAGTGC TACACCTACAGCTGG >OriGene 3' read for NM_014308 unedited
CCATAGGNATGGCACTTCCAGGNCCAGNAAAGCACTGGGNGAGGGTCACAGGGATGCCAC CCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAAAGGATCCTAGACC ATGCTAATGGTCAGGGACTTCAGAGGTCAATTTACCCATCCTTCTCCTTCTACTGCCAGG AATCTAAGAGGCTATGGGGTCTGGCCCTTCTCTCTCTGATAGCTGTTGCTTTCCCAGAAC CCTGAGGCCCCAGAAACCCTCTACTCCCAGCCCCTGCTCATTGCAGGACCCACAGTGGGA CTATGGCTCTGCACAGGGCCATTCAGTTCTCCACAGAGAGGGACTGTCCTGGAGGGGTGG CCGAGGAGGTTGCCCCAGGGCTTCTGTCCAGTCTGGCGCTGGGCCCACACTAGGGCAGAG CTCCACTGAAAGTCATGATGGGCAGGCAGAGAAGGGAGCAGAGATCAGGTGCGGCCTGGG CCGGCAGGTCAGGAGGCGTCTGGGGTGGTGAGGAGAGGTCGCTCTTCTCTGGCTTGTAGC ACGGTGAGACCTCACATCTGACTACACTCTGCAGGATCTTTCTCTCATCCTGGTCCAGGC ACACAGCAAAGGGGCAGCTGTTGGAGCCGATGATCTGCACCTTGTCCACTTTGATCTGCG ATGTGCTAATCTGGTTAAAGCCCTTCTTGGATTTGGAGTTCTGCCTTTTCACCACTTCTG TCANGTTTAGCGTCAGGGCCTCCATGCTGGAATCCAGCTNCTCCTGCTTTTCCGCAGCCT TTGTTGANGTTCACGGGAGTACAGACCTTCTNCAGNTTGCTCCAGCGACTTCGTCCACTG ATGGCCCCCTTGCTGNTAATATCTGTAGTGGTAGAGAACAGCCTNCCNGTCGCATCGATG CCAGCCGCTGCTGCCG |
| Restriction Sites | Please inquire |
| ACCN | NM_014308 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | There is 1 nucleotide difference between the OriGene clone and the NCBI reference ORF. These result in the substitution of 1 aa. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_014308.1, NP_055123.1 |
| RefSeq Size | 3255 bp |
| RefSeq ORF | 2643 bp |
| Locus ID | 23533 |
| UniProt ID | Q8WYR1 |
| Protein Families | Druggable Genome |
| Protein Pathways | Acute myeloid leukemia, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Glioma, Insulin signaling pathway, Jak-STAT signaling pathway, Leukocyte transendothelial migration, Melanoma, mTOR signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway |
| Gene Summary | Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011] Transcript Variant: This variant (2) differs in the 5' UTR exon, compared to variant 1. Both variants 1 and 2 encode the same isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222249 | PIK3R5 (Myc-DDK-tagged)-Human phosphoinositide-3-kinase, regulatory subunit 5 (PIK3R5), transcript variant 2 |
CNY 6,448.00 |
|
| RC222249L1 | Lenti ORF clone of Human phosphoinositide-3-kinase, regulatory subunit 5 (PIK3R5), transcript variant 2, Myc-DDK-tagged |
CNY 8,848.00 |
|
| RC222249L2 | Lenti ORF clone of Human phosphoinositide-3-kinase, regulatory subunit 5 (PIK3R5), transcript variant 2, mGFP tagged |
CNY 9,030.00 |
|
| RC222249L3 | Lenti ORF clone of Human phosphoinositide-3-kinase, regulatory subunit 5 (PIK3R5), transcript variant 2, Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC222249L4 | Lenti ORF clone of Human phosphoinositide-3-kinase, regulatory subunit 5 (PIK3R5), transcript variant 2, mGFP tagged |
CNY 9,030.00 |
|
| RG222249 | PIK3R5 (tGFP-tagged) - Human phosphoinositide-3-kinase, regulatory subunit 5 (PIK3R5), transcript variant 2 |
CNY 8,048.00 |
