United States
Germany
Japan
United Kingdom
China
CACNB1 (NM_199247) Human Untagged Clone
CAT＃: SC307910
CACNB1 (untagged)-Human calcium channel, voltage-dependent, beta 1 subunit (CACNB1), transcript variant 2
CNY 3,904.00
CNY 8,460.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CAB1; CACNLB1; CCHLB1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_199247 edited
GGCAGCCGAAGGCCGAGCTGGGTGGCTGGACCGGGTGCTGGCTGCGCCGCGCTGCTTTCG GCTCCCACGGCCTCTCCCATGCGCTGAGGGAGCCCGGCTGGGCCGGGCCGGCGGCGGGAG GGGAGGCTCCTCTCCATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCC CAGGAGATCCCCATGGAGGTCTTCGACCCCAGCCCGCAGGGCAAATACAGCAAGAGGAAA GGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACCACATCCAACAGCTTTGTC CGCCAGGGCTCAGCGGAGTCCTACACCAGCCGTCCATCAGACTCTGATGTATCTCTGGAG GAGGACCGGGAAGCCTTAAGGAAGGAAGCAGAGCGCCAGGCATTAGCGCAGCTCGAGAAG GCCAAGACCAAGCCAGTGGCATTTGCTGTGCGGACAAATGTTGGCTACAATCCGTCTCCA GGGGATGAGGTGCCTGTGCAGGGAGTGGCCATCACCTTCGAGCCCAAAGACTTCCTGCAC ATCAAGGAGAAATACAATAATGACTGGTGGATCGGGCGGCTGGTGAAGGAGGGCTGTGAG GTTGGCTTCATTCCCAGCCCCGTCAAACTGGACAGCCTTCGCCTGCTGCAGGAACAGAAG CTGCGCCAGAACCGCCTCGGCTCCAGCAAATCAGGCGATAACTCCAGTTCCAGTCTGGGA GATGTGGTGACTGGCACCCGCCGCCCCACACCCCCTGCCAGTGGTAATGAAATGACTAAC TTAGCCTTTGAACTAGACCCCCTAGAGTTAGAGGAGGAAGAGGCTGAGCTTGGTGAGCAG AGTGGCTCTGCCAAGACTAGTGTTAGCAGTGTCACCACCCCGCCACCCCATGGCAAACGC ATCCCCTTCTTTAAGAAGACAGAGCATGTGCCCCCCTATGACGTGGTGCCTTCCATGAGG CCCATCATCCTGGTGGGACCGTCGCTCAAGGGCTACGAGGTTACAGACATGATGCAGAAA GCTTTATTTGACTTCTTGAAGCATCGGTTTGATGGCAGGATCTCCATCACTCGTGTGACG GCAGATATTTCCCTGGCTAAGCGCTCAGTTCTCAACAACCCCAGCAAACACATCATCATT GAGCGCTCCAACACACGCTCCAGCCTGGCTGAGGTGCAGAGTGAAATCGAGCGAATCTTC GAGCTGGCCCGGACCCTTCAGTTGGTCGCTCTGGATGCTGACACCATCAATCACCCAGCC CAGCTGTCCAAGACCTCGCTGGCCCCCATCATTGTTTACATCAAGATCACCTCTCCCAAG GTACTTCAAAGGCTCATCAAGTCCCGAGGAAAGTCTCAGTCCAAACACCTCAATGTCCAA ATAGCGGCCTCGGAAAAGCTGGCACAGTGCCCCCCTGAAATGTTTGACATCATCCTGGAT GAGAACCAATTGGAGGATGCCTGCGAGCATCTGGCGGAGTACTTGGAAGCCTATTGGAAG GCCACACACCCGCCCAGCAGCACGCCACCCAATCCGCTGCTGAACCGCACCATGGCTACC GCAGCCCTGGCTGCCAGCCCTGCCCCTGTCTCCAACCTCCAGGTACAGGTGCTCACCTCG CTCAGGAGAAACCTCGGCTTCTGGGGCGGGCTGGAGTCCTCACAGCGGGGCAGTGTGGTG CCCCAGGAGCAGGAACATGCCATGTAGTGGGCGCCCTGCCCGTCTTCCCTCCTGCTCTGG GGTCGGAACTGGAGTGCAGGGAACATGGAGGAGGAAGGGAAGAGCTTTATTTTGTAAAAA AATAAGATGAGCGGCAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_199247 unedited
TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGCAGCCGAAGGCCGA GCTGGGTGGCTGGACCGGGTGCTGGCTGCGCCGCGCTGCTTTCGGCTCCCACGGCCTCTC CCATGCGCTGAGGGAGCCCGGCTGGGCCGGGCCGGCGGCGGGAGGGGAGGCTCCTCTCCA TGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCAGGAGATCCCCATGG AGGTCTTCGACCCCAGCCCGCAGGGCAAATACAGCAAGAGGAAAGGGCGATTCAAACGGT CAGATGGGAGCACGTCCTCGGATACCACATCCAACAGCTTTGTCCGCCAGGGCTCAGCGG AGTCCTACACCAGCCGTCCATCAGACTCTGATGTATCTCTGGAGGAGGACCGGGAAGCCT TAAGGAAGGAAGCAGAGCGCCAGGCATTAGCGCAGCTCGAGAAGGCCAAGACCAAGCCAG TGGCATTTGCTGTGCGGACAAATGTTGGCTACAATCCGTCTCCAGGGGATGAGGTGCCTG TGCAGGGAGTGGCCATCACCTTCGAGCCCAAAGACTTCCTGCACATCAAGGAGAAATACA ATAATGACTGGTGGATCGGGCGGCTGGTGAAGGAGGGCTGTGAGGTTGGCTTCATTCCCA GCCCCGTCAAACTGGACAGCCTTCGCCTGCTGCAGGAACAGAAGCTGCGCCAGAACCGCC TCGGCTCCAGCANATCAGGGCGATACTCCAGNTCCAGTCTGGGAGATGTGGTGACTGGCA CCCGCCGCCCCACACCCCCTGCCAGTGGTAATGAAATGACTAACTTAGCCTNTGAACTAN ACCCCCTANATTAGAAGAGGAAGAGGCTGACCTGGTGAGCANAGTGGCTCTGCCAGACTA TGTTAGCAGTGGACCACCCCGCACCCATGGNAACGCATCCCTTTT >OriGene 3' read for NM_199247 unedited
GGCCGCATTCTANAGTCGAGTTTTTTTTTTTTTTTTTTGCCGCTCATCTTATTTTTTTAC AAAATAAAGCTCTTCCCTTCCTCCTCCATGTTCCCTGCACTCCAGTTCCGACCCCAGAGC AGGAGGGAAGACGGGCAGGGCGCCCACTACATGGCATGTTCCTGCTCCTGGGGCACCACA CTGCCCCGCTGTGAGGACTCCAGCCCGCCCCAGAAGCCGAGGTTTCTCCTGAGCGAGGTG AGCACCTGTACCTGGAGGTTGGAGACAGGGGCAGGGCTGGCAGCCAGGGCTGCGGTAGCC ATGGTGCGGTTCAACAGCGGATTGGGTGGCGTGCTGCTGGGCGGGTGTGTGGCCTTCCAA TAGGCTTCCAAGTACTCCGCCAGATGCTCGCAGGCATCCTCCAATTGGTTCTCATCCAGG ATGATGTCAAACATTTCAGGGGGGCACTGTGCCAGCTTTTCCGAGGCCGCTATTTGGACA TTGAGGTGTTTGGACTGAGACTTTCCTCGGGACTTGATGAGCCTTTGAAGTACCTTGGGA GAGGTGATCTTGATGTAAACAATGATGGGGGCCAGCGAGGTCTTGGACAGCTGGGCTGGG TGATTGATGGTGTCAGCATCCAGAGCGACCAACTGAAGGGTCCGGGCCAGCTCGAAGATT CGCTCGATTTCACTCTGCACCCTCACCAGGCTGGAGCGTGTGTTGGAGCGCTCAATGATG ATGTGTTTGCTGGGGGTTGTTGAAAACTGAGCGCTTATCCAAGGAAATATCTGCCGCCCA ACGAGTGATGGAGATCCCGCCATCAACCGATCCTTCAAGAGTCAAAAAAGCTTCTGCCTC AGTCTGGAACCTCGACCCTTGACCCACGCCCACCCAGAGATGGGGCCCATGGAAGGACCA CGTATAAGGGGGCCATGCCTCTGCCCTTAAAAAAGGGAACCCTTCCCTGGGGGGCGCGGG GGGACCCGTCACAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_199247 |
| Insert Size | 1800 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_199247.1, NP_954855.1 |
| RefSeq Size | 1847 bp |
| RefSeq ORF | 1572 bp |
| Locus ID | 782 |
| UniProt ID | Q02641 |
| Protein Families | Druggable Genome, Ion Channels: Other |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway |
| Gene Summary | The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2), also known as beta-1M, betaC, and beta-1a, differs in the 3' UTR and has multiple coding region differences, compared to variant 1. It encodes isoform 2 which has a distinct C-terminus, compared to isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217910 | CACNB1 (Myc-DDK-tagged)-Human calcium channel, voltage-dependent, beta 1 subunit (CACNB1), transcript variant 2 |
CNY 3,896.00 |
|
| RC217910L1 | Lenti ORF clone of Human calcium channel, voltage-dependent, beta 1 subunit (CACNB1), transcript variant 2, Myc-DDK-tagged |
CNY 6,296.00 |
|
| RC217910L2 | Lenti ORF clone of Human calcium channel, voltage-dependent, beta 1 subunit (CACNB1), transcript variant 2, mGFP tagged |
CNY 6,370.00 |
|
| RC217910L3 | Lenti ORF clone of Human calcium channel, voltage-dependent, beta 1 subunit (CACNB1), transcript variant 2, Myc-DDK-tagged |
CNY 6,370.00 |
|
| RC217910L4 | Lenti ORF clone of Human calcium channel, voltage-dependent, beta 1 subunit (CACNB1), transcript variant 2, mGFP tagged |
CNY 6,370.00 |
|
| RG217910 | CACNB1 (tGFP-tagged) - Human calcium channel, voltage-dependent, beta 1 subunit (CACNB1), transcript variant 2 |
CNY 5,496.00 |
