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Nav1.5 (SCN5A) (NM_198056) Human Untagged Clone
CAT＃: SC307625
SCN5A (untagged)-Human sodium channel, voltage-gated, type V, alpha subunit (SCN5A), transcript variant 1
CNY 13,320.00
货期*
现货
规格
| Cited in 2 publications. |
Product images
经常一起买 (4)
SCN5A mouse monoclonal antibody,clone OTI5E9
CNY 1,999.00
CNY 3,600.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_198056 edited
CCGAGACGGCGGCGGCGCCCGTAGGATGCAGGGATCGCTCCCCCGGGGCCGCTGAGCCTG CGCCCAGTGCCCCGAGCCCCGCGCCGAGCCGAGTCCGCGCCAAGCAGCAGCCGCCCACCC CGGGGCCCGGCCGGGGGACCAGCAGCTTCCCCACAGGCAACGTGAGGAGAGCCTGTGCCC AGAAGCAGGATGAGAAGATGGCAAACTTCCTATTACCTCGGGGCACCAGCAGCTTCCGCA GGTTCACACGGGAGTCCCTGGCAGCCATCGAGAAGCGCATGGCGGAGAAGCAAGCCCGCG GCTCAACCACCTTGCAGGAGAGCCGAGAGGGGCTG:CCCGAGGAGGAGGCTCCCCGG:CC CCAGCTGGACCTGCAGG:CCTCCAAAAAGCTGCCAGATCTCTATGGCAATCCACCCCAAG AGCTCATCGGAGAGCCCCTGGAGGACCTGGACCCCTTCTATAGCACCCAAAAGACTTTCA TCGTACTGAATAAAGGCAAGACCATCTTCCGGTTCAGTGCCACCAACGCCTTGTATGTCC TCAGTCCCTTCCACCCCATCCGGAGAGCGGCTGTGAAGATTCTGGTTCACTCGCTCTTCA ACATGCTCATCATGTGCACCATCCTCACCAACTGCGTGTTCATGGCCCAGCACGACCCTC CACCCTGGACCAAGTATGTCGAGTACACCTTCACCGCCATTTACACCTTTGAGTCTCTGG TCAAGATTCTGGCTCGAGGCTTCTGCCTGCACGCGTTCACTTTCCTTCGGGACCCATGGA ACTGGCTGGACTTTAGTGTGATTATCATGGCATACACAACTGAATTTGTGGACCTGGGCA ATGTCTCAGCCTTACGCACCTTCCGAGTCCTCCGGGCCCTGAAAACTATATCAGTCATTT CAGGGCTGAAGACCATCGTGGGGGCCCTGATCCAGTCTGTGAAGAAGCTGGCTGATGTGA TGGTCCTCACAGTCTTCTGCCTCAGCGTCTTTGCCCTCATCGGCCTGCAGCTCTTCATGG GCAACCTAAGGCACAAGTGCGTGCGCAACTTCACAGCGCTCAACGGCACCAACGGCTCCG TGGAGGCCGACGGCTTGGTCTGGGAATCCCTGGACCTTTACCTCAGTGATCCAGAAAATT ACCTGCTCAAGAACGGCACCTCTGATGTGTTACTGTGTGGGAACAGCTCTGACGCTGGGA CATGTCCGGAGGGCTACCGGTGCCTAAAGGCAGGCGAGAACCCCGACCACGGCTACACCA GCTTCGATTCCTTTGCCTGGGCCTTTCTTGCACTCTTCCGCCTGATGACGCAGGACTGCT GGGAGCGCCTCTATCAGCAGACCCTCAGGTCCGCAGGGAAGATCTACATGATCTTCTTCA TGCTTGTCATCTTCCTGGGGTCCTTCTACCTGGTGAACCTGATCCTGGCCGTGGTCGCAA TGGCCTATGAGGAGCAAAACCAAGCCACCATCGCTGAGACCGAGGAGAAGGAAAAGCGCT TCCAGGAGGCCATGGAAATGCTCAAGAAAGAACACGAGGCCCTCACCATCAGGGGTGTGG ATACCGTGTCCCGTAGCTCCTTGGAGATGTCCCCTTTGGCCCCAGTAAACAGCCATGAGA GAAGAAGCAAGAGGAGAAAACGGATGTCTTCAGGAACTGAGGAGTGTGGGGAGGACAGGC TCCCCAAGTCTGACTCAGAAGATGGTCCCAGAGCAATGAATCATCTCAGCCTCACCCGTG GCCTCAGCAGGACTTCTATGAAGCCACGTTCCAGCCGCGGGAGCATTTTCACCTTTCGCA GGCGAGACCTGGGTTCTGAAGCAGATTTTGCAGATGATGAAAACAGCACAGCGGGGGAGA GCGAGAGCCACCGCACATCACTGCTGGTGCCCTGGCCCCTGCGCCGGACCAGTGCCCAGG GACAGCCCAGTCCCGGAACCTCGGCTCCTGGCCACGCCCTCCATGGCAAAAAGAACAGCA CTGTGGACTGCAATGGGGTGGTCTCATTACTGGGGGCAGGCGACCCAGAGGCCACATCCC CAGGAAGCCACCTCCTCCGCCCTGTGATGCTAGAGCACCCGCCAGACACGACCACGCCAT CGGAGGAGCCAGGCGGGCCCCAGATGCTGACCTCCCAGGCTCCGTGTGTAGATGGCTTCG AGGAGCCAGGAGCACGGCAGCGGGCCCTCAGCGCAGTCAGCGTCCTCACCAGCGCACTGG AAGAGTTAGAGGAGTCTCGCCACAAGTGTCCACCATGCTGGAACCGTCTCGCCCAGCGCT ACCTGATCTGGGAGTGCTGCCCGCTGTGGATGTCCATCAAGCAGGGAGTGAAGTTGGTGG TCATGGACCCGTTTACTGACCTCACCATCACTATGTGCATCGTACTCAACACACTCTTCA TGGCGCTGGAGCACTACAACATGACAAGTGAATTCGAGGAGATGCTGCAGGTCGGAAACC TGGTCTTCACAGGGATTTTCACAGCAGAGATGACCTTCAAGATCATTGCCCTCGACCCCT ACTACTACTTCCAACAGGGCTGGAACATCTTCGACAGCATCATCGTCATCCTTAGCCTCA TGGAGCTGGGCCTGTCCCGCATGAGCAACTTGTCGGTGCTGCGCTCCTTCCGCCTGCTGC GGGTCTTCAAGCTGGCCAAATCATGGCCCACCCTGAACACACTCATCAAGATCATCGGGA ACTCAGTGGGGGCACTGGGGAACCTGACACTGGTGCTAGCCATCATCGTGTTCATCTTTG CTGTGGTGGGCATGCAGCTCTTTGGCAAGAACTACTCGGAGCTGAGGGACAGCGACTCAG GCCTGCTGCCTCGCTGGCACATGATGGACTTCTTTCATGCCTTCCTCATCATCTTCCGCA TCCTCTGTGGAGAGTGGATCGAGACCATGTGGGACTGCATGGAGGTGTCGGGGCAGTCAT TATGCCTGCTGGTCTTCTTGCTTGTTATGGTCATTGGCAACCTTGTGGTCCTGAATCTCT TCCTGGCCTTGCTGCTCAGCTCCTTCAGTGCAGACAACCTCACAGCCCCTGATGAGGACA GAGAGATGAACAACCTCCAGCTGGCCCTGGCCCGCATCCAGAGGGGCCTGCGCTTTGTCA AGCGGACCACCTGGGATTTCTGCTGTGGTCTCCTGCGGCAGCGGCCTCAGAAGCCCGCAG CCCTTGCCGCCCAGGGCCAGCTGCCCAGCTGCATTGCCACCCCCTACTCCCCGCCACCCC CAGAGACGGAGAAGGTGCCTCCCACCCGCAAGGAAACACGGTTTGAGGAAGGCGAGCAAC CAGGCCAGGGCACCCCCGGGGATCCAGAGCCCGTGTGTGTGCCCATCGCTGTGGCCGAGT CAGACACAGATGACCAAGAAGAGGATGAGGAGAACAGCCTGGGCACGGAGGAGGAGTCCA GCAAGCAGCAGGAATCCCAGCCTGTGTCCGGTGGCCCAGAGGCCCCTCCGGATTCCAGGA CCTGGAGCCAGGTGTCAGCGACTGCCTCCTCTGAGGCCGAGGCCAGTGCATCTCAGGCCG ACTGGCGGCAGCAGTGGAAAGCGGAACCCCAGGCCCCAGGGTGCGGTGAGACCCCAGAGG ACAGTTGCTCCGAGGGCAGCACAGCAGACATGACCAACACCGCTGAGCTCCTGGAGCAGA TCCCTGACCTCGGCCAGGATGTCAAGGACCCAGAGGACTGCTTCACTGAAGGCTGTGTCC GGCGCTGTCCCTGCTGTGCGGTGGACACCACACAGGCCCCAGGGAAGGTCTGGTGGCGGT TGCGCAAGACCTGCTACCACATCGTGGAGCACAGCTGGTTCGAGACATTCATCATCTTCA TGATCCTACTCAGCAGTGGAGCGCTGGCCTTCGAGGACATCTACCTAGAGGAGCGGAAGA CCATCAAGGTTCTGCTTGAGTATGCCGACAAGATGTTCACATATGTCTTCGTGCTGGAGA TGCTGCTCAAGTGGGTGGCCTACGGCTTCAAGAAGTACTTCACCAATGCCTGGTGCTGGC TCGACTTCCTCATCGTAGACGTCTCTCTGGTCAGCCTGGTGGCCAACACCCTGGGCTTTG CCGAGATGGGCCCCATCAAGTCACTGCGGACGCTGCGTGCACTCCGTCCTCTGAGAGCTC TGTCACGATTTGAGGGCATGAGGGTGGTGGTCAATGCCCTGGTGGGCGCCATCCCGTCCA TCATGAACGTCCTCCTCGTCTGCCTCATCTTCTGGCTCATCTTCAGCATCATGGGCGTGA ACCTCTTTGCGGGGAAGTTTGGGAGGTGCATCAACCAGACAGAGGGAGACTTGCCTTTGA ACTACACCATCGTGAACAACAAGAGCCAGTGTGAGTCCTTGAACTTGACCGGAGAATTGT ACTGGACCAAGGTGAAAGTCAACTTTGACAACGTGGGGGCCGGGTACCTGGCCCTTCTGC AGGTGGCAACATTTAAAGGCTGGATGGACATTATGTATGCAGCTGTGGACTCCAGGGGGT ATGAAGAGCAGCCTCAGTGGGAATACAACCTCTACATGTACATCTATTTTGTCATTTTCA TCATCTTTGGGTCTTTCTTCACCCTGAACCTCTTTATTGGTGTCATCATTGACAACTTCA ACCAACAGAAGAAAAAGTTAGGGGGCCAGGACATCTTCATGACAGAGGAGCAGAAGAAGT ACTACAATGCCATGAAGAAGCTGGGCTCCAAGAAGCCCCAGAAGCCCATCCCACGGCCCC TGAACAAGTACCAGGGCTTCATATTCGACATTGTGACCAAGCAGGCCTTTGACGTCACCA TCATGTTTCTGATCTGCTTGAATATGGTGACCATGATGGTGGAGACAGATGACCAAAGTC CTGAGAAAATCAACATCTTGGCCAAGATCAACCTGCTCTTTGTGGCCATCTTCACAGGCG AGTGTATTGTCAAGCTGGCTGCCCTGCGCCACTACTACTTCACCAACAGCTGGAATATCT TCGACTTCGTGGTTGTCATCCTCTCCATCGTGGGCACTGTGCTCTCGGACATCATCCAGA AGTACTTCTTCTCCCCGACGCTCTTCCGAGTCATCCGCCTGGCCCGAATAGGCCGCATCC TCAGACTGATCCGAGGGGCCAAGGGGATCCGCACGCTGCTCTTTGCCCTCATGATGTCCC TGCCTGCCCTCTTCAACATCGGGCTGCTGCTCTTCCTCGTCATGTTCATCTACTCCATCT TTGGCATGGCCAACTTCGCTTATGTCAAGTGGGAGGCTGGCATCGACGACATGTTCAACT TCCAGACCTTCGCCAACAGCATGCTGTGCCTCTTCCAGATCACCACGTCGGCCGGCTGGG ATGGCCTCCTCAGCCCCATCCTCAACACTGGGCCGCCCTACTGCGACCCCACTCTGCCCA ACAGCAATGGCTCTCGGGGGGACTGCGGGAGCCCAGCCGTGGGCATCCTCTTCTTCACCA CCTACATCATCATCTCCTTCCTCATCGTGGTCAACATGTACATTGCCATCATCCTGGAGA ACTTCAGCGTGGCCACGGAGGAGAGCACCGAGCCCCTGAGTGAGGACGACTTCGATATGT TCTATGAGATCTGGGAGAAATTTGACCCAGAGGCCACTCAGTTTATTGAGTATTCGGTCC TGTCTGACTTTGCCGATGCCCTGTCTGAGCCACTCCGTATCGCCAAGCCCAACCAGATAA GCCTCATCAACATGGACCTGCCCATGGTGAGTGGGGACCGCATCCATTGCATGGACATTC TCTTTGCCTTCACCAAAAGGGTCCTGGGGGAGTCTGGGGAGATGGACGCCCTGAAGATCC AGATGGAGGAGAAGTTCATGGCAGCCAACCCATCCAAGATCTCCTACGAGCCCATCACCA CCACACTCCGGCGCAAGCACGAAGAGGTGTCGGCCATGGTTATCCAGAGAGCCTTCCGCA GGCACCTGCTGCAACGCTCTTTGAAGCATGCCTCCTTCCTCTTCCGTCAGCAGGCGGGCA GCGGCCTCTCCGAAGAGGATGCCCCTGAGCGAGAGGGCCTCATCGCCTACGTGATGAGTG AGAACTTCTCCCGACCCCTTGGCCCACCCTCCAGCTCCTCCATCTCCTCCACTTCCTTCC CACCCTCCTATGACAGTGTCACTAGAGCCACCAGCGATAACCTCCAGGTGCGGGGGTCTG ACTACAGCCACAGTGAAGATCTCGCCGACTTCCCCCCTTCTCCGGACAGGGACCGTGAGT CCATCGTGTGAGCCTCGGCCTGGCTGGCCAGGACACACTGAAAAGCAGCCTTTTTCACCA TGGCAAACCTAAATGCAGTCAGTCACAAACCAGCCTGGGGCCTTCCTGGCTTTGGGAGTA AGAAATGGGCCTCAGCCCCGCGGATCAACCAGGCAGAGTTCTGTGGCGCCGCGTGGACAG CCGGAGCAGTTGGCCTGTGCTTGGAGGCCTCAGATAGACCTGTGACCTGGTCTGGTCAGG CAATGCCCTGCGGCTCTGGAAAGCAACTTCATCCCAGCTGCTGAGGCGAAATATAAAACT GAGACTGTATATGTTGTGAATGGGCTTTCATAAATTTATTATATTTGATATTTTTTTACT TGAGCAAAGAACTAAGGATTTTTCCATGGACATGGGCAGCAATTCACGCTGTCTCTTCTT AACCCTGAACAAGAGTGTCTATGGAGCAGCCGGAAGTCTGTTCTCAAAGCAGAAGTGGAA TCCAGTGTGGCTCCCACAGGTCTTCACTGCCCAGGGGTCGAATGGGGTCCCCCTCCCACT TGACCTGAGATGCTGGGAGGGCTGAACCCCCACTCACACAAGCACACACACACAGTCCTC ACACACGGAGGCCAGACACAGGCCGTGGGACCCAGGCTCCCAGCCTAAGGGAGACAGGCC TTTCCCTGCCGGCCCCCCAAGGATGGGGTTCTTGTCCACGGGGCTCACTCTGGCCCCCTA TTGTCTCCAAGGTCCCATTTTCCCCCTGTGTTTTCACGCAGGTCATATTGTCAGTCCTAC AAAAATAAAAGGCTTCCAGAGGAGAGTGGCCTGGGTCCCAGGGCTGGCCCTAGGCACTGA TAGTTGCCTTTTCTTCCCCTCCTGTAAGAGTATTAACAAAACCAAAGGACACAAGGGTGC AAGCCCCATTCACGGCCTGGCATGCAGCTTGTCCTTGCTCCTGGAACCTGGCAGGCCCTG CCCAGCCAGCCATCGGAAGAGAGGGCTGAGCCATGGGGGTTTGGGGCTAAGAAGTTCACC AGCCCTGAGCCATGGCGGCCCCTCAGCCTGCCTGAAGAGAGGAAACTGGCGATCTCCCAG GGCTCTCTGGACCATACGCGGAGGAGTTTTCTGTGTGGTCTCCAGCTCCTCTCCAGACAC AGAGACATGGGAGTGGGGAGCGGAGCTTGGCCCTGCGCCCTGTGCAGGGAAAGGGATGGT CAGGCCCAGTTCTCGTGCCCTTAGAGGGGAATGAACCATGGCACCTTTGAGAGAGGGGGC ACTGTGGTCAGGCCCAGCCTCTCTGGCTCAGCCCGGGATCCTGATGGCACCCACACAGAG GACCTCTTTGGGGCAAGATCCAGGTGGTCCCATAGGTCTTGTGAAAAGGCTTTTTCAGGG AAAAATATTTTACTAGTCCAATCACCCCCAGGACCTCTTCAGCTGCTGACAATCCTATTT AGCATATGCAAATCTTTTAACATAGAGAACTGTCACCCTGAGGTAACAGGGTCAACTGGC GAAGCCTGAGCAGGCAGGGGCTTGGCTGCCCCATTCCAGCTCTCCCATGGAGCCCCTCCA CCGGGCGCATGCCTCCCAGGCCACCTCAGTCTCACCTGCCGGCTCTGGGCTGGCTGCTCC TAACCTACCTCGCCGAGCTGTCGGAGGGCTGGACATTTGTGGCAGTGCTGAAGGGGGCAT TGCCGGCGAGTAAAGTATTATGTTTCTTCTTGTCACCCCAGTTCCCTTGGTGGCAACCCC AGACCCAACCCATGCCCCTGACAGATCTAGTTCTCTTCTCCTGTGTTCCCTTTGAGTCCA GTGTGGGACACGGTTTAACTGTCCCAGCGACATTTCTCCAAGTGGAAATCCTATTTTTGT AGATCTCCATGCTTTGCTCTCAAGGCTTGGAGAGGTATGTGCCCCTCCTGGGTGCTCACC GCCTGCTACACAGGCAGGAATGCGGTTGGGAGGCAGGTCGGGCTGCCAGCCCAGCTGGCC GGAAGGAGACTGTGGTTTTTGTGTGTGTGGACAGCCCGGGAGCTTTGAGACAGGTGCCTG GGGCTGGCTGCAGACGGTGTGGTTGGGGGTGGGAGGTGAGCTAGACCCAACCCTTAGCTT TTAGCCTGGCTGTCACCTTTTTAATTTCCAGAACTGCACAATGACCAGCAGGAGGGGAGA AGAGAGTAGGAAAAAGGAGGGAAGGACAGACATCAAGTGCCAGATGTTGTCTGAACTAAT CGAGCACTTCTCACCAAACTTCATGTATAAATAAAATACATATTTTTAAAACAAACCAAT AAATGGCTTACATGAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_198056 |
| Insert Size | 8600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to contain one SNP compared with NM_198056.1. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_198056.1, NP_932173.1 |
| RefSeq Size | 8527 bp |
| RefSeq ORF | 6051 bp |
| Locus ID | 6331 |
| UniProt ID | Q14524 |
| Protein Families | Druggable Genome, Ion Channels: Sodium, Transmembrane |
| Gene Summary | The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the longest isoform (a). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
A Teflon-based system for applying multidirectional voltages to lipid bilayers as a novel platform for membrane proteins
,Komiya, M;Kanomata, K;Yokota, R;Tsuneta, Y;,
arXiv preprint arXiv
[SCN5A]
|
|
Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendami
,Herzig, V;Ikonomopoulou, M;Smith, JJ;Dziemborowicz, S;Gilchrist, J;Kuhn-Nentwig, L;Rezende, FO;Moreira, LA;Nicholson, GM;Bosmans, F;King, GF;,
Sci Rep
,PubMed ID 27383378
[SCN5A]
|
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214786 | SCN5A (Myc-DDK-tagged)-Human sodium channel, voltage-gated, type V, alpha subunit (SCN5A), transcript variant 1 |
CNY 13,312.00 |
|
| RC214786L1 | Lenti ORF clone of Human sodium channel, voltage-gated, type V, alpha subunit (SCN5A), transcript variant 1, Myc-DDK-tagged |
CNY 15,712.00 |
|
| RG214786 | SCN5A (tGFP-tagged) - Human sodium channel, voltage-gated, type V, alpha subunit (SCN5A), transcript variant 1 |
CNY 14,912.00 |
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