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KLB (NM_175737) Human Untagged Clone
CAT＃: SC307023
KLB (untagged)-Human klotho beta (KLB)
CNY 10,912.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BKL |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_175737 edited
TCCTCAGTCTCCCAGTTCAAGCTAATCATTGACAGAGCTTTACAATCACAAGCTTTTACT GAAGCTTTGATAAGACAGTCCAGCAGTTGGTGGCAAATGAAGCCAGGCTGTGCGGCAGGA TCTCCAGGGAATGAATGGATTTTCTTCAGCACTGATGAAATAACCACACGCTATAGGAAT ACAATGTCCAACGGGGGATTGCAAAGATCTGTCATCCTGTCAGCACTTATTCTGCTACGA GCTGTTACTGGATTCTCTGGAGATGGAAGAGCTATATGGTCTAAAAATCCTAATTTTACT CCGGTAAATGAAAGTCAGCTGTTTCTCTATGACACTTTCCCTAAAAACTTTTTCTGGGGT ATTGGGACTGGAGCATTGCAAGTGGAAGGGAGTTGGAAGAAGGATGGAAAAGGACCTTCT ATATGGGATCATTTCATCCACACACACCTTAAAAATGTCAGCAGCACGAATGGTTCCAGT GACAGTTATATTTTTCTGGAAAAAGACTTATCAGCCCTGGATTTTATAGGAGTTTCTTTT TATCAATTTTCAATTTCCTGGCCAAGGCTTTTCCCCGATGGAATAGTAACAGTTGCCAAC GCAAAAGGTCTGCAGTACTACAGTACTCTTCTGGACGCTCTAGTGCTTAGAAACATTGAA CCTATAGTTACTTTATACCACTGGGATTTGCCTTTGGCACTACAAGAAAAATATGGGGGG TGGAAAAATGATACCATAATAGATATCTTCAATGACTATGCCACATACTGTTTCCAGATG TTTGGGGACCGTGTCAAATATTGGATTACAATTCACAACCCATATCTAGTGGCTTGGCAT GGGTATGGGACAGGTATGCATGCCCCTGGAGAGAAGGGAAATTTAGCAGCTGTCTACACT GTGGGACACAACTTGATCAAGGCTCACTCGAAAGTTTGGCATAACTACAACACACATTTC CGCCCACATCAGAAGGGTTGGTTATCGATCACGTTGGGATCTCATTGGATCGAGCCAAAC CGGTCGGAAAACACGATGGATATATTCAAATGTCAACAATCCATGGTTTCTGTGCTTGGA TGGTTTGCCAACCCTATCCATGGGGATGGCGACTATCCAGAGGGGATGAGAAAGAAGTTG TTCTCCGTTCTACCCATTTTCTCTGAAGCAGAGAAGCATGAGATGAGAGGCACAGCTGAT TTCTTTGCCTTTTCTTTTGGACCCAACAACTTCAAGCCCCTAAACACCATGGCTAAAATG GGACAAAATGTTTCACTTAATTTAAGAGAAGCGCTGAACTGGATTAAACTGGAATACAAC AACCCTCGAATCTTGATTGCTGAGAATGGCTGGTTCACAGACAGTCGTGTGAAAACAGAA GACACCACGGCCATCTACATGATGAAGAATTTCCTCAGCCAGGTGCTTCAAGCAATAAGG TTAGATGAAATACGAGTGTTTGGTTATACTGCCTGGTCTCTCCTGGATGGCTTTGAATGG CAGGATGCTTACACCATCCGCCGAGGATTATTTTATGTGGATTTTAACAGTAAACAGAAA GAGCGGAAACCTAAGTCTTCAGCACACTACTACAAACAGATCATACGAGAAAATGGTTTT TCTTTAAAAGAGTCCACGCCAGATGTGCAGGGCCAGTTTCCCTGTGACTTCTCCTGGGGT GTCACTGAATCTGTTCTTAAGCCCGAGTCTGTGGCTTCGTCCCCACAGTTCAGCGATCCT CATCTGTACGTGTGGAACGCCACTGGCAACAGACTGTTGCACCGAGTGGAAGGGGTGAGG CTGAAAACACGACCCGCTCAATGCACAGATTTTGTAAACATCAAAAAACAACTTGAGATG TTGGCAAGAATGAAAGTCACCCACTACCGGTTTGCTCTGGATTGGGCCTCGGTCCTTCCC ACTGGCAACCTGTCCGCGGTGAACCGACAGGCCCTGAGGTACTACAGGTGCGTGGTCAGT GAGGGGCTGAAGCTTGGCATCTCCGCGATGGTCACCCTGTATTATCCGACCCACGCCCAC CTAGGCCTCCCCGAGCCTCTGTTGCATGCCGACGGGTGGCTGAACCCATCGACGGCCGAG GCCTTCCAGGCCTACGCTGGGCTGTGCTTCCAGGAGCTGGGGGACCTGGTGAAGCTCTGG ATCACCATCAACGAGCCTAACCGGCTAAGTGACATCTACAACCGCTCTGGCAACGACACC TACGGGGCGGCGCACAACCTGCTGGTGGCCCACGCCCTGGCCTGGCGCCTCTACGACCGG CAGTTCAGGCCCTCACAGCGCGGGGCCGTGTCGCTGTCGCTGCACGCGGACTGGGCGGAA CCCGCCAACCCCTATGCTGACTCGCACTGGAGGGCGGCCGAGCGCTTCCTGCAGTTCGAG ATCGCCTGGTTCGCCGAGCCGCTCTTCAAGACCGGGGACTACCCCGCGGCCATGAGGGAA TACATTGCCTCCAAGCACCGACGGGGGCTTTCCAGCTCGGCCCTGCCGCGCCTCACCGAG GCCGAAAGGAGGCTGCTCAAGGGCACGGTCGACTTCTGCGCGCTCAACCACTTCACCACT AGGTTCGTGATGCACGAGCAGCTGGCCGGCAGCCGCTACGACTCGGACAGGGACATCCAG TTTCTGCAGGACATCACCCGCCTGAGCTCCCCCACGCGCCTGGCTGTGATTCCCTGGGGG GTGCGCAAGCTGCTGCGGTGGGTCCGGAGGAACTACGGCGACATGGACATTTACATCACC GCCAGTGGCATCGACGACCAGGCTCTGGAGGATGACCGGCTCCGGAAGTACCACCTAGGG AAGTACCTTCAGGAGGTGCTGAAAGCATACCTGATTGATAAAGTCAGAATCAAAGGCTAT TATGCATTCAAACTGGCTGAAGAGAAATCTAAACCCAGATTTGGATTCTTCACATCTGAT TTTAAAGCTAAATCCTCAATACAATTTTACAACAAAGTGATCAGCAGCAGGGGCTTCCCT TTTGAGAACAGTAGTTCTAGATGCAGTCAGACCCAAGAAAATACAGAGTGCACTGTCTGC TTATTCCTTGTGCAGAAGAAACCACTGATATTCCTGGGTTGTTGCTTCTTCTCCACCCTG GTTCTACTCTTATCAATTGCCATTTTTCAAAGGCAGAAGAGAAGAAAGTTTTGGAAAGCA AAAAACTTACAACACATACCATTAAAGAAAGGCAAGAGAGTTGTTAGCTAAACTGATCTG TCTGCATGATAGACAGTTTAAAAATTCATCCCAGTTCCATATGCTGGTAACTTACAGGAG ATATACCTGTATTATAGAAAGACAATCTGAGATACAGCTGTAACCAAGGTGATGACAATT GTCTCTGCTGTGTGGTTCAAAGAACATTCCCTTAGGTGTTGACATCAGTGAACTCAGTTC TTGGATGTAAACATAAAGGCTTCATCCTGACAGTAAGCTATGAGGATTACATGCTACATT GCTTCTTAAAGTTTCATCAACTGTATTCCATCATTCTGCTTTAGCTTTCATCTCTACCAA TAGCTACTTGTGGTACAATAAATTATTTTTAAGAAGTAAAAAAAAAAAAAAAAAA >Reverse primer walk for NM_175737 unedited
CTGCCAACATTCGGATGAGCCTTGTCAATTGTGTCCCACGTGTAGAACGCTGCTAAATTT CCCTTCTCTCCGGGGCATGCATACCTGTCCCATACCCATGCCAAGCCACTAGATATGGGT TGTGAATTGTAATCCAATATTTGACACGGTCCCCAAACATCTGGAAACAGTATGTGGCAT AGTCATTGAAGATATCTATTATGGTATCATTTTTCCACCCCCCATATTTTTCTTGTAGTG CCAAAGGCAAATCCCAGTGGTATAAAGTAACTATAGGTTCAATGTTTCTAAGCACTAGAG CGTCCAGAAGAGTACTGTAGTACTGCAGACCTTTTGCGTTGGCAACTGTTACTATTCCAT CGGGGAAAAGCCTTGGCCAGGAAATTGAAAATTGATAAAAAGAAACTCCTATAAAATCCA GGGCTGATAAGTCTTTTTCCAGAAAAATATAACTGTCACTGGAACCATTCGTGCTGCTGA CATTTTTAAGGTGTGTGTGGATGAAATGATCCCATATAGAAGGTCCTTTTCCATCCTTCT TCCAACTCCCTTCCACTTGCAATGCTCCAGTCCCAATACCCCAGAAAAAGTTTTTAGGGA AAGTGTCATAGAGAAACAGCTGACTTTCATTTACCGGAGTAAAATTAGGATTTTTAGACC ATATAGCTCTTCCATCTCCAGAGAATCCAGTAACAGCTCGTAGCAGAATAAGTGCTGACA GGATGACAGATCTTTTGCATCCCCCGTTGGACATTGTATTCCTATAGCGTGTGGTTATTT CATCAGTGCTGAAGAAAATCATTCATTCCCTGNAGATCCTGCCGCACAGCCTGGCTTCAT TTGCCACCAACTGCTG >Forward primer walk for NM_175737 unedited
ATCTCCCTGGAACAAACTCTCTACATGTTCTTTGCTTGTGNAAGCATACCTGATTGATAA AGTCAGAATCAAAGGCTATTATGCATTCAAACTGGCTGAAGAGAAATCTAAACCCAGATT TGGATTCTTCACATCTGATTTTAAAGCTAAATCCTCAATACAATTTTACAACAAAGTGAT CAGCAGCAGGGGCTTCCCTTTTGAGAACAGTAGTTCTAGATGCAGTCAGACCCAAGAAAA TACAGAGTGCACTGTCTGCTTATTCCTTGTGCAGAAGAAACCACTGATATTCCTGGGTTG TTGCTTCTTCTCCACCCTGGTTCTACTCTTATCAATTGCCATTTTTCAAAGGCAGAAGAG AAGAAAGTTTTGGAAAGCAAAAAACTTACAACACATACCATTAAAGAAAGGCAAGAGAGT TGTTAGCTAAACTGATCTGTCTGCATGATAGACAGTTTAAAAATTCATCCCAGTTCCATA TGCTGGTAACTTACAGGAGATATACCTGTATTATAGAAAGACAATCTGAGATACAGCTGT AACCAAGGTGATGACAATTGTCTCTGCTGTGTGGTTCAAAGAACATTCCCTTAGGTGTTG ACATCAGTGAACTCAGTTCTTGGATGTAAACATAAAGGCTTCATCCTGACAGTAAGCTAT GAGGATTACATGCTACATTGCTTCTTAAAGTTTCATCAACTGTATTCCATCATTCTGCTT TAGCTTTCATCTCTACCAATAGCTACTTGTGGTACAATAAATTATTTTTAAGAAGTAAAA AAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTT |
| Restriction Sites | Please inquire |
| ACCN | NM_175737 |
| Insert Size | 3600 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_175737.2, NP_783864.1 |
| RefSeq Size | 3279 bp |
| RefSeq ORF | 3135 bp |
| Locus ID | 152831 |
| UniProt ID | Q86Z14 |
| Protein Families | Transmembrane |
| Gene Summary | Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21 (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211186 | KLB (Myc-DDK-tagged)-Human klotho beta (KLB) |
CNY 7,272.00 |
|
| RC211186L1 | Lenti-ORF clone of KLB (Myc-DDK-tagged)-Human klotho beta (KLB) |
CNY 9,672.00 |
|
| RC211186L2 | Lenti-ORF clone of KLB (mGFP-tagged)-Human klotho beta (KLB) |
CNY 9,672.00 |
|
| RC211186L3 | Lenti-ORF clone of KLB (Myc-DDK-tagged)-Human klotho beta (KLB) |
CNY 9,672.00 |
|
| RC211186L4 | Lenti-ORF clone of KLB (mGFP-tagged)-Human klotho beta (KLB) |
CNY 9,672.00 |
|
| RG211186 | KLB (tGFP-tagged) - Human klotho beta (KLB) |
CNY 8,872.00 |
