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PNLDC1 (NM_173516) Human Untagged Clone
CAT＃: SC306842
PNLDC1 (untagged)-Human poly(A)-specific ribonuclease (PARN)-like domain containing 1 (PNLDC1)
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HsPNLDC1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC306842 representing NM_173516.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGTTCTGCACCCGAGGACTGCTATTTTTTGCCTTCCTGGCAGGTCTGGACATAGAGTTCACGGGCCTT CGTTCTAACCTGTCTGGGCCCCAGCAGATCAGTCTTTTTGATTTGCCATCGGAGTGGTATCTAAAGACC CGTCAGAGTGTTCAGCAATTTACAGTCTGTCAGATTGGATTGTCTGTGTTTTCCGCTATTGAAGGAGAG GCAAACAAGTATATAGCCCATTCTTGTAACTTCTATCTCTTCCCTACAACGTTTGGGATTTTGGACTCA GAATTCTCCTTCCAGGCTTCCAGTGTTCAGTTTTTGAATCAGTATGGCTTCAACTATAACAAGTTTCTC AAAAACGGAATCCCATATATGAATGAAGAACAGGAGAAGAAAATTAGACACGATATCCTGACTGGGAAC TGGAGAGTTCGCAGCTCTCCGGATAAAGACCAAATCAAGGTGGTGATTGACGAAGTGACGCGGTGGCTG GAGCTGGCCAAGGAAGGCGACTGGATGACTCTTCCTGGGATCACTGGCTTCCAGGCCTTTGAGGTCCAA CTGGTGCTGAGGCAGGCCCTCCCCAACATCTGGACGGTGCTGAAAGATGAGGGGGTGGTAGTGAAGAAA GTGAGTAAACAACATCGTTGGTATCTTCAGAACACCTCTTGTGACCGAGAGAGCTGTTGGAAGGAAAAT ATTCTTCTCTCAGCAAGGGGTTTTTCTGTCTTTTTCCAAATGCTGGTGAAAGCCCAGAAGCCCTTAGTG GGACATAATATGATGATGGACCTGCTGCACCTCCATGAGAAGTTCTTCAGACCCCTCCCAGAAAGCTAC GATCAATTTAAGCAGAATATCCACAGCCTATTTCCTGTTCTCATTGATACCAAGAGTGTAACAAAGGAT ATCTGGAAGGAGATGAATTTCCCGAGGGTGTCGAATCTTTCGGAAGTCTATGAAGTCCTGAACAGTGAC TTGAATCCCACCAAGAATTCTGGACCAGAGATTGTTCACGCGAGCAGGTGTGAGAAATATGTTGAGACA AAGTGCCCCCACGAAGCCGCGTATGATGCCTTCCTCTGTGGGTCAGTTCTTTTGAAAGTGGCACACTTG CTTCTACAGAAGATATACCACATCGACCCCGTGCCCGAGTCATCCTTTCCTCAGTACCTTGACGTGCTG GCTCCTTACGTGAACCAAGTGAACCTCATCCGAGCGGGGGTCCCAAAGATCAATTTTTCTGGTCCAGAT TATCCCAGTATCCGACCTCCCATCCTCATCCTCAGCGTCAAAAGGTGGCCTGGGGTCAGCGAGCAGCAA GTCTACCATAAGTTTCAGAATCTCTGCAAGTTTGATGTCAGGCGACTCACAAGAAGCCAGTTCTTACTC CTGACCAATAAGTTTAAGGATGCGCGGAACATCCTGAAGGAGTACCGGGACCACCCGACCCTGTGCATC TCCCTGTACCGCTACTGGAGGCACTCCCCAAACGTCAACTGCCTGCTCCAAGTCTGTGGCATAGTGACT GCCTGGGCCCTTCTCGCGTTCATCCTTGGAAGATCTGGTACCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_173516 |
| Insert Size | 1563 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_173516.2 |
| RefSeq Size | 1958 bp |
| RefSeq ORF | 1563 bp |
| Locus ID | 154197 |
| UniProt ID | Q8NA58 |
| MW | 60.1 kDa |
| Gene Summary | 3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails (PubMed:27515512). Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development (PubMed:27515512). May act as a regulator of multipotency in embryonic stem cells (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR and initiates translation at an alternate downstream start codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct N-terminus, compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221944 | PNLDC1 (Myc-DDK-tagged)-Human poly(A)-specific ribonuclease (PARN)-like domain containing 1 (PNLDC1) |
CNY 3,872.00 |
|
| RC221944L3 | Lenti ORF clone of Human poly(A)-specific ribonuclease (PARN)-like domain containing 1 (PNLDC1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC221944L4 | Lenti ORF clone of Human poly(A)-specific ribonuclease (PARN)-like domain containing 1 (PNLDC1), mGFP tagged |
CNY 5,890.00 |
|
| RG221944 | PNLDC1 (tGFP-tagged) - Human poly(A)-specific ribonuclease (PARN)-like domain containing 1 (PNLDC1) |
CNY 5,472.00 |
