KREMEN1 (NM_153379) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	FLJ31863; KREMEM1; KREMEN; kringle-coding gene marking the eye and the nose; kringle-containing transmembrane protein 1; kringle containing transmembrane protein 1; KRM1; KRM1, KREMEN, KREMEM1, FLJ31863; OTTHUMP00000028977
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene ORF sequence for NM_153379 edited ATGGCGCCGCCAGCCGCCCGCCTCGCCCTGCTCTCCGCCGCGGCGCTCACGCTGGCGGCC CGGCCCGCGCCTAGCCCCGGCCTCGGCCCCGAGTGTTTCACAGCCAATGGTGCGGATTAT AGGGGAACACAGAACTGGACAGCACTACAAGGCGGGAAGCCATGTCTGTTTTGGAACGAG ACTTTCCAGCATCCATACAACACTCTGAAATACCCCAACGGGGAGGGGGGCCTGGGTGAG CACAACTATTGCAGAAATCCAGATGGAGACGTGAGCCCCTGGTGCTATGTGGCAGAGCAC GAGGATGGTGTCTACTGGAAGTACTGTGAGATACCTGCTTGCCAGATGCCTGGAAACCTT GGCTGCTACAAGGATCATGGAAACCCACCTCCTCTAACTGGCACCAGTAAAACGTCCAAC AAACTCACCATACAAACTTGCATCAGTTTTTGTCGGAGTCAGAGGTTCAAGTTTGCTGGG ATGGAGTCAGGCTATGCTTGCTTCTGTGGAAACAATCCTGATTACTGGAAGTACGGGGAG GCAGCCAGTACCGAATGCAACAGCGTCTGCTTCGGGGATCACACCCAACCCTGTGGTGGC GATGGCAGGATCATCCTCTTTGATACTCTCGTGGGCGCCTGCGGTGGGAACTACTCAGCC ATGTCTTCTGTGGTCTATTCCCCTGACTTCCCCGACACCTATGCCAC:GGGGAGGGTCTG CTACTGGACCATCCGGGTTCCGGGGGCCTCCCACATCCACTTCAGCTTCCCCCTATTTGA CATCAGGGACTCGGCGGACATGGTGGAGCTTCTGGATGGCTACACCCACCGTGTCCTAGC CCGCTTCCACGGGAGGAGCCGCCCACCTCTGTCCTTCAACGTCTCTCTGGACTTCGTCAT CTTGTATTTCTTCTCTGATCGCATCAATCAGGCCCAGGGATTTGCTGTTTTATACCAAGC CGTCAAGGAAGAACTGCCACAGGAGAGGCCCGCTGTCAACCAGACGGTGGCCGAGGTGAT CACGGAGCAGGCCAACCTCAGTGTCAGCGCTGCCCGGTCCTCCAAAGTCCTCTATGTCAT CACCACCAGCCCCAGCCACCCACCTCAGACTGTCCCAGGTAGCAATTCCTGGGCGCCACC CATGGGGGCTGGAAGCCACAGAGTTGAAGGATGGACAGTCTATGGTCTGGCAACTCTCCT CATCCTCACAGTCACAGCCATTGTAGCAAAGATACTTCTGCACGTCACATTCAAATCCCA TCGTGTTCCTGCTTCAGGGGACCTTAGGGATTGTCATCAACCAGGGACTTCGGGGGAAAT CTGGAGCATTTTTTACAAGCCTTCCACTTCAATTTCCATCTTTAAGAAGAAACTCAAGGG TCAGAGTCAACAAGATGACCGCAATCCCCTTGTGAGTGACTAA
Restriction Sites	Please inquire
ACCN	NM_153379
Insert Size	3000 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	The ORF of this clone has been fully sequenced and found to be a perfect match to NM_153379.1.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_153379.1, NP_700358.1
RefSeq Size	1821 bp
RefSeq ORF	1422 bp
Locus ID	83999
Protein Families	Druggable Genome, Transmembrane
Gene Summary	This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the shorter isoform (1).

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