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MCOLN2 (NM_153259) Human Untagged Clone
CAT＃: SC306572
MCOLN2 (untagged)-Human mucolipin 2 (MCOLN2)
CNY 4,224.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | TRP-ML2; TRPML2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_153259 edited
ATGGCCCGGCAGCCTTATCGTTTTCCCCAGGCAAGGATTCCGGAGAGAGGATCAGGTGTT TTCAGGTTAACCGTCAGAAACGCAATGGCACATCGTGATTCTGAGATGAAAGAAGAATGT CTAAGGGAAGACCTGAAGTTTTACTTCATGAGCCCTTGTGAAAAATACCGAGCCAGACGC CAGATTCCGTGGAAACTGGGTTTGCAGATTTTGAAGATAGTCATGGTCACCACACAGCTT GTTCGTTTTGGTTTAAGTAACCAGCTGGTGGTTGCTTTCAAAGAAGATAACACTGTTGCT TTTAAGCACTTGTTTTTGAAAGGATATTCTGGTACAGATGAAGATGACTACAGCTGCAGT GTATATACTCAAGAGGATGCCTATGAGAGCATCTTTTTTGCTATTAATCAGTATCATCAG CTAAAGGACATTACCCTGGGGACCCTTGGTTATGGAGAAAATGAAGACAATAGAATTGGC TTAAAAGTCTGTAAGCAGCATTACAAGAAAGGGACCATGTTTCCTTCTAATGAGACACTG AATATTGACAACGACGTTGAGCTCGATTGTGTTCAATTAGACCTTCAGGACCTCTCCAAG AAGCCTCCGGACTGGAAGAACTCATCATTCTTCAGACTGGAATTTTATCGGCTCTTACAG GTTGAAATCTCCTTTCATCTTAAAGGCATTGACCTACAGACAATTCATTCCCGTGAGTTA CCAGACTGTTATGTCTTTCAGAATACGATTATCTTTGACAATAAAGCTCACAGTGGCAAA ATCAAAATCTATTTTGACAGTGATGCCAAAATTGAAGAATGTAAAGACTTGAACATATTT GGATCTACTCAGAAAAATGCTCAGTATGTCCTGGTGTTTGATGCATTTGTCATTGTGATT TGCTTGGCATCTCTTATTCTGTGTACAAGATCCATTGTTCTTGCTCTAAGGTTACGGAAG AGATTTCTAAATTTCTTCCTGGAGAAGTACAAGCGGCCTGTGTGTGACACCGACCAGTGG GAGTTCATCAACGGCTGGTATGTCCTGGTGATTATCAGCGACCTAATGACAATCATTGGC TCCATATTAAAAATGGAAATCAAAGCAAAGAATCTCACAAACTATGATCTCTGCAGCATT TTTCTTGGAACCTCTACGCTCTTGGTTTGGGTTGGAGTCATCAGATACCTGGGTTATTTC CAGGCATATAATGTGCTGATTTTAACAATGCAGGCCTCACTGCCAAAAGTTCTTCGGTTT TGTGCTTGTGCTGGTATGATTTATCTGGGTTACACATTCTGTGGCTGGATTGTCTTAGGA CCATACCATGACAAGTTTGAAAATCTGAACACAGTTGCTGAGTGTCTGTTTTCTCTGGTC AACGGTGATGACATGTTTGCAACCTTTGCCCAAATCCAGCAGAAGAGCATCTTGGTGTGG CTGTTCAGTCGTCTGTATTTATATTCCTTCATCAGCCTTTTTATATATATGATTCTCAGT CTTTTTATTGCACTTATTACAGATTCTTATGACACCATTAAGAAATTCCAACAGAATGGG TTTCCTGAAACGGATTTGCAGGAATTCCTGAAGGAATGCAGTAGCAAAGAAGAGTATCAG AAAGAGTCCTCAGCCTTCCTGTCCTGCATCTGCTGTCGGAGGAGGAAAAGAAGTGATGAT CACTTGATACCTATTAGCTAA |
| Restriction Sites | Please inquire |
| ACCN | NM_153259 |
| Insert Size | 1700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_153259.2, NP_694991.2 |
| RefSeq Size | 3060 bp |
| RefSeq ORF | 1701 bp |
| Locus ID | 255231 |
| UniProt ID | Q8IZK6 |
| Protein Families | Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane |
| Gene Summary | Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al., 2007 [PubMed 17662026]).[supplied by OMIM, Sep 2009] Transcript Variant: This variant (1) encodes the longer isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211195 | MCOLN2 (Myc-DDK-tagged)-Human mucolipin 2 (MCOLN2) |
CNY 4,216.00 |
|
| RC211195L1 | Lenti ORF clone of Human mucolipin 2 (MCOLN2), Myc-DDK-tagged |
CNY 6,616.00 |
|
| RC211195L2 | Lenti ORF clone of Human mucolipin 2 (MCOLN2), mGFP tagged |
CNY 6,460.00 |
|
| RC211195L3 | Lenti ORF clone of Human mucolipin 2 (MCOLN2), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC211195L4 | Lenti ORF clone of Human mucolipin 2 (MCOLN2), mGFP tagged |
CNY 6,460.00 |
|
| RG211195 | MCOLN2 (tGFP-tagged) - Human mucolipin 2 (MCOLN2) |
CNY 5,816.00 |
