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SGOL2 (SGO2) (NM_152524) Human Untagged Clone
CAT＃: SC306430
SGOL2 (untagged)-Human shugoshin-like 2 (S. pombe) (SGOL2), transcript variant 1
CNY 10,450.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | SGOL2; TRIPIN |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC306430 representing NM_152524.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGAGTGCCCAGTGATGGAAACTGGCTCACTTTTTACCTCAGGAATTAAGAGACATTTGAAAGACAAA AGAATTTCAAAGACTACTAAGTTGAATGTTTCTCTTGCTTCAAAAATAAAAACAAAAATACTAAATAAT TCTTCTATTTTCAAAATATCTTTAAAGCACAACAACAGGGCATTAGCTCAGGCTCTTAGTAGAGAAAAA GAGAATTCTCGAAGAATTACAACTGAAAAGATGCTATTGCAAAAAGAAGTAGAGAAACTGAATTTTGAG AACACATTTCTTCGCCTAAAGCTAAATAACTTGAATAAGAAGCTTATAGACATAGAAGCTCTCATGAAC AATAACTTGATAACTGCAATTGAAATGAGCAGTCTTTCTGAGTTCCATCAGAGTTCCTTTCTACTGTCA GCTAGCAAGAAGAAACGAATTAGTAAACAGTGCAAGTTGATGCGTCTTCCATTTGCAAGGGTTCCATTA ACTTCAAATGATGATGAAGATGAAGATAAAGAGAAAATGCAGTGTGACAACAATATTAAATCAAAGACA TTACCTGATATTCCCTCTTCAGGATCAACAACACAACCTTTATCAACTCAGGATAATTCGGAAGTGTTA TTTCTTAAAGAAAATAATCAAAATGTATATGGTTTAGATGATTCAGAACATATTTCTTCTATAGTTGAT GTACCTCCCAGAGAAAGCCATTCCCACTCAGACCAAAGTTCTAAGACTTCTCTAATGAGTGAGATGAGA AACGCCCAGTCTATTGGCCGCAGATGGGAGAAACCATCTCCTAGTAATGTGACTGAAAGGAAGAAGCGT GGGTCATCTTGGGAATCAAATAATCTTTCTGCAGACACTCCCTGTGCAACAGTTTTAGATAAACAACAC ATTTCAAGTCCAGAATTAAATTGCAATAATGAGATAAATGGTCATACTAATGAAACAAATACTGAAATG CAAAGAAATAAACAGGATCTTCCTGGCTTATCTTCTGAGTCTGCCAGAGAACCTAATGCAGAGTGCATG AATCAAATTGAGGATAATGATGACTTTCAATTGCAGAAAACTGTGTATGATGCTGACATGGATTTAACT GCTAGTGAAGTCAGCAAAATTGTCACAGTCTCAACAGGCATTAAAAAGAAAAGTAATAAAAAAACAAAT GAACATGGAATGAAAACTTTCAGAAAAGTGAAAGATTCCAGCTCTGAAAAAAAGAGAGAAAGATCAAAG AGACAGTTTAAAAATAGTTCAGATGTCGATATTGGGGAAAAGATTGAAAACAGGACAGAAAGATCTGAT GTCCTGGATGGCAAAAGGGGTGCAGAAGATCCCGGTTTTATTTTCAATAATGAACAGCTGGCTCAGATG AATGAACAGCTGGCTCAGGTGAATGAACTAAAGAAAATGACCCTTCAAACTGGCTTTGAACAAGGTGAC AGAGAAAATGTACTGTGTAATAAAAAGGAGAAAAGAATAACAAATGAGCAAGAGGAAACATACTCTTTA TCCCAAAGTTCAGGTAAATTTCACCAGGAGAGTAAATTTGATAAGGGTCAGAATTCCCTAACTTGTAAT AAAAGTAAAGCTTCTAGACAGACATTTGTGATTCACAAATTAGAAAAAGATAACTTACTCCCAAACCAA AAGGATAAAGTAACCATTTATGAAAACCTAGACGTCACAAATGAATTTCACACAGCCAATCTTTCCACC AAAGATAATGGAAATTTATGTGATTATGGGACCCACAATATATTGGATTTGAAAAAGTATGTCACTGAT ATTCAACCCTCAGAGCAAAATGAATCAAACATTAATAAGCTTAGAAAGAAAGTAAACCGGAAGACAGAA ATAATTTCTGGAATGAACCACATGTATGAGGATAATGATAAAGATGTGGTGCATGGCCTAAAAAAAGGT AATTTTTTTTTCAAAACCCAAGAGGATAAAGAACCTATCTCTGAAAACATAGAAGTTTCCAAAGAGCTT CAAATCCCAGCTCTTTCTACTAGAGATAATGAAAATCAATGTGACTATAGGACCCAGAATGTGTTGGGT TTGCAAAAGCAGATCACCAATATGTACCCCGTTCAGCAAAATGAATCAAAAGTTAATAAGAAGCTTAGG CAGAAAGTAAATCGGAAGACAGAAATAATTTCTGAAGTGAATCATTTAGATAATGACAAAAGTATAGAA TACACAGTTAAAAGTCACTCACTCTTTTTAACGCAAAAAGATAAGGAAATCATCCCTGGAAACCTAGAA GACCCAAGTGAGTTTGAAACACCTGCTCTTTCTACCAAAGATAGTGGAAACCTGTATGATTCTGAGATT CAAAATGTTTTGGGGGTGAAACATGGCCATGATATGCAACCTGCTTGTCAAAATGATTCAAAAATAGGT AAGAAGCCTAGACTAAATGTATGTCAAAAGTCAGAAATAATTCCTGAAACCAACCAAATATATGAGAAT GATAACAAAGGTGTACATGACCTAGAAAAAGATAACTTCTTCTCTCTAACCCCAAAGGATAAAGAAACA ATTTCTGAAAATCTACAAGTCACAAATGAATTTCAAACAGTTGATCTTCTCATCAAAGATAATGGAAAT TTATGTGATTATGACACCCAGAATATATTGGAGTTGAAAAAGTATGTTACTGATAGGAAATCTGCTGAG CAAAATGAATCAAAAATAAATAAGCTCAGGAATAAAGTGAATTGGAAGACAGAAATAATTTCTGAAATG AACCAGATATATGAGGATAATGATAAAGATGCACATGTCCAAGAAAGCTATACAAAAGATCTTGATTTT AAAGTAAATAAATCTAAACAAAAACTTGAATGCCAAGACATTATCAATAAACACTATATGGAAGTCAAC AGTAATGAAAAGGAAAGTTGTGATCAAATTTTAGATTCCTACAAAGTAGTTAAAAAACGTAAGAAAGAA TCATCATGCAAGGCAAAGAACATTTTGACAAAAGCTAAGAACAAACTTGCTTCACAGTTAACAGAATCT TCACAGACATCTATCTCCTTAGAATCTGATTTAAAACATATTACTAGTGAAGCAGATTCTGATCCAGGA AACCCAGTTGAACTATGTAAGACTCAGAAGCAAAGCACTACCACTTTGAATAAAAAAGATCTCCCTTTT GTGGAAGAAATAAAAGAAGGAGAGTGTCAGGTTAAAAAGGTAAATAAAATGACATCTAAGTCAAAGAAA AGGAAGACCTCCATAGATCCTTCTCCAGAGAGCCATGAAGTAATGGAAAGAATACTTGACAGCGTTCAG GGAAAGTCTACTGTATCTGAACAAGCTGATAAGGAAAACAATTTGGAGAATGAGAAAATGGTCAAAAAT AAGCCAGACTTTTACACAAAGGCATTTAGATCTTTGTCTGAGATACATTCACCTAACATACAAGATTCT TCCTTTGACAGTGTTCGTGAAGGTTTAGTACCTTTGAGCGTTTCTTCTGGTAAAAATGTGATAATAAAA GAAAATTTTGCCTTGGAGTGCTCCCCAGCCTTTCAAGTAAGTGATGATGAGCATGAGAAGATGAACAAG ATGAAATTTAAAGTCAACCGGAGAACCCAAAAATCAGGAATAGGTGATAGACCATTACAGGACTTGTCA AATACCAGTTTTGTTTCAAATAACACTGCTGAATCTGAAAATAAGTCAGAAGATCTATCTTCAGAACGG ACAAGCAGAAGAAGAAGGTGTACTCCTTTCTATTTTAAAGAGCCAAGCCTCAGAGACAAGATGAGAAGA TGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_152524 |
| Insert Size | 3798 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_152524.5 |
| RefSeq Size | 4542 bp |
| RefSeq ORF | 3798 bp |
| Locus ID | 151246 |
| UniProt ID | Q562F6 |
| MW | 144.7 kDa |
| Gene Summary | Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments. Involved in centromeric enrichment of AUKRB in prometaphase.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210349 | SGOL2 (Myc-DDK-tagged)-Human shugoshin-like 2 (S. pombe) (SGOL2), transcript variant 1 |
CNY 13,208.00 |
|
| RC210349L1 | Lenti-ORF clone of SGOL2 (Myc-DDK-tagged)-Human shugoshin-like 2 (S. pombe) (SGOL2), transcript variant 1 |
CNY 15,608.00 |
|
| RC210349L2 | Lenti-ORF clone of SGOL2 (mGFP-tagged)-Human shugoshin-like 2 (S. pombe) (SGOL2), transcript variant 1 |
CNY 15,608.00 |
|
| RC210349L3 | Lenti-ORF clone of SGOL2 (Myc-DDK-tagged)-Human shugoshin-like 2 (S. pombe) (SGOL2), transcript variant 1 |
CNY 14,540.00 |
|
| RC210349L4 | Lenti-ORF clone of SGOL2 (mGFP-tagged)-Human shugoshin-like 2 (S. pombe) (SGOL2), transcript variant 1 |
CNY 14,540.00 |
|
| RG210349 | SGOL2 (tGFP-tagged) - Human shugoshin-like 2 (S. pombe) (SGOL2), transcript variant 1 |
CNY 13,870.00 |
