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PTPRN2 (NM_130843) Human Untagged Clone
CAT＃: SC305917
PTPRN2 (untagged)-Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 3
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IA-2beta; IAR; ICAAR; PTPRP; R-PTP-N2 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_130843, the custom clone sequence may differ by one or more nucleotides
ATGGGGCCGCCGCTCCCGCTGCTGCTGCTGCTACTGCTGCTGCTGCCGCCACGCGTCCTG CCTGCCGCCCCTTCGTCCGTCCCCCGCGGCCGGCAGCTCCCGGGGCGTCTGGGCTGCCTG CTCGAGGAGGGCCTCTGCGGAGCGTCCGAGGCCTGTGTGAACGATGGAGTGTTTGGAAGG TGCCAGAAGGTTCCGGCAATGGACTTTTACCGCTACGAGGTGTCGCCCGTGGCCCTGCAG CGCCTGCGCGTGGCGTTGCAGAAGCTTTCCGGCACAGGTTTCACGTGGCAGGATGACTAT ACTCAGTATGTGATGGACCAGGAACTTGCAGACCTCCCGAAAACCTACCTGAGGCGTCCT GAAGCATCCAGCCCAGCCAGGCCCTCAAAACACAGCGTTGGCAGCGAGAGGAGGTACAGT CGGGAGGGCGGTGCTGCCCTGGCCAACGCCCTCCGACGCCACCTGCCCTTCCTGGAGGCC CTGTCCCAGGCCCCAGCCTCAGACGTGCTCGCCAGGACCCATACGGCGCAGGACAGACCC CCCGCTGAGGGTGATGACCGCTTCTCCGAGAGCATCCTGACCTATGTGGCCCACACGTCT GCGCTGACCTACCCTCCCGGGTCCCGGACCCAGCTCCGCGAGGACCTCCTGCCGCGGACC CTCGGCCAGCTCCAGCCAGATGAGCTCAGCCCTAAGGTGGACAGTGGTGTGGACAGACAC CATCTGATGGCGGCCCTCAGTGCCTATGCTGCCCAGAGGCCCCCAGCTCCCCCCGGGGAG GGCAGCCTGGAGCCACAGTACCTTCTGCGTGCACCCTCAAGAATGCCCAGGCCTTTGCTG GCACCAGCCGCCCCCCAGAAGTGGCCTTCACCTCTGGGAGATTCCGAAGACCCCTCCAGC ACAGGCGATGGAGCACGGATTCATACCCTCCTGAAGGACCTGCAGAGGCAGCCGGCTGAG GTGAGGGGCCTGAGTGGCCTGGAGCTGGACGGCATGGCTGAGCTGATGGCTGGCCTGATG CAAGGCGTGGACCATGGAGTAGCTCGAGGCAGCCCTGGGAGAGCGGCCCTGGGAGAGTCT GGAGAACAGGCGGATGGCCCCAAGGCCACCCTCCGTGGAGACAGCTTTCCAGATGACGGA GTGCAGGACGACGATGATAGACTTTACCAAGAGGTCCATCGTCTGAGTGCCACACTCGGG GGCCTCCTGCAGGACCACGGGTCTCGACTCTTACCTGGAGCCCTCCCCTTTGCAAGGCCC CTCGACATGGAGAGGAAGAAGTCCGAGCACCCTGAGTCTTCCCTGTCTTCAGAAGAGGAG ACTGCCGGAGTGGAGAACGTCAAGAGCCAGACGTATTCCAAAGATCTGCTGGGGCAGCAG CCGCATTCGGAGCCCGGGGCCGCTGCGTTTGGGGAGCTCCAAAACCAGATGCCTGGGCCC TCGAAGGAGGAGCAGAGCCTTCCAGCGGGTGCTCAGGAGGCCCTCAGCGACGGCCTGCAA TTGGAGGTCCAGCCTTCCGAGGAAGAGGCGCGGGGCTACATCGTGACAGACAGAGAGGTT CTCGGACCAGCAGTGACCTTCAAAGTGAGCGCCAATGTCCAAAACGTGACCACTGAGGAT GTGGAGAAGGCCACAGTTGACAACAAAGACAAACTGGAGGAAACCTCTGGACTGAAAATT CTTCAAACCGGAGTCGGGTCGAAAAGCAAACTCAAGTTCCTGCCTCCTCAGGCGGAGCAA GAAGACTCCACCAAGTTCATCGCGCTCACCCTGGTCTCCCTCGCCTGCATCCTGGGCGTC CTCCTGGCCTCTGGCCTCATCTACTGCCTCCGCCATAGCTCTCAGCACAGGCTGAAGGAG AAGCTCTCGGGACTAGGGGGCGACCCAGGTGCAGATGCCACTGCCGCCTACCAGGAGCTG TGCCGCCAGCGTATGGCCACGCGGCCACCAGACCGACCTGAGGGCCCGCACACGTCACGC ATCAGCAGCGTCTCATCCCAGTTCAGCGACGGGCCGATCCCCAGCCCCTCCGCACGCAGC AGCGCCTCATCCTGGTCCGAGGAGCCTGTGCAGTCCAACATGGACATCTCCACCGGCCAC ATGATCCTGTCCTACATGGAGGACCACCTGAAGAACAAGAACCGGCTGGAGAAGGAGTGG GAAGCGCTGTGCGCCTACCAGGCGGAGCCCAACAGCTCGTTCGTGGCCCAGAGGGAGGAG AACGTGCCCAAGAACCGCTCCCTGGCCGTGCTGACCTATGACCACTCCCGGGTCCTGCTG AAGGCGGAGAACAGCCACAGCCACTCAGACTACATCAACGCTAGCCCCATCATGGATCAC GACCCGAGGAACCCCGCGTACATCGCCACCCAGGGACCGCTGCCCGCCACCGTGGCTGAC TTTTGGCAGATGGTGTGGGAGAGCGGCTGCGTGGTGATCGTCATGCTGACACCCCTCGCG GAGAACGGCGTCCGGCAGTGCTACCACTACTGGCCGGATGAAGGCTCCAATCTCTACCAC ATCTATGAGGTGAACCTGGTCTCCGAGCACATCTGGTGTGAGGACTTCCTGGTGAGGAGC TTCTATCTGAAGAACCTGCAGACCAACGAGACGCGCACCGTGACGCAGTTCCACTTCCTG AGTTGGTATGACCGAGGAGTCCCTTCCTCCTCAAGGTCCCTCCTGGACTTCCGCAGAAAA GTAAACAAGTGCTACAGGGGCCGTTCTTGTCCAATAATTGTTCATTGCAGTGACGGTGCA GGCCGGAGCGGCACCTACGTCCTGATCGACATGGTTCTCAACAAGATGGCCAAAGGTGCT AAAGAGATTGATATCGCAGCGACCCTGGAGCACTTGAGGGACCAGAGACCCGGCATGGTC CAGACGAAGGAGCAGTTTGAGTTCGCGCTGACAGCCGTGGCTGAGGAGGTGAACGCCATC CTCAAGGCCCTTCCCCAGTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_130843 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_130843.1, NP_570858.1 |
| RefSeq Size | 4680 bp |
| RefSeq ORF | 2961 bp |
| Locus ID | 5799 |
| UniProt ID | Q92932 |
| Domains | Y_phosphatase, PTPc_motif |
| Protein Families | Druggable Genome, Phosphatase |
| Protein Pathways | Type I diabetes mellitus |
| Gene Summary | This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015] Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (3) that is shorter than isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205368 | PTPRN2 (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 3 |
CNY 7,224.00 |
|
| RC205368L3 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 3, Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC205368L4 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 3, mGFP tagged |
CNY 9,030.00 |
|
| RG205368 | PTPRN2 (tGFP-tagged) - Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 3 |
CNY 8,824.00 |
