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SOX6 (NM_017508) Human Untagged Clone
CAT＃: SC304470
SOX6 (untagged)-Human SRY (sex determining region Y)-box 6 (SOX6), transcript variant 1
CNY 8,840.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HSSOX6; SOXD; TOLCAS |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>NCBI ORF sequence for NM_017508, the custom clone sequence may differ by one or more nucleotides
ATGGGAAGAATGTCTTCCAAGCAAGCCACCTCTCCATTTGCCTGTGCAGCTGATGGAGAGGATGCAATGA CCCAGGATTTAACCTCAAGGGAAAAGGAAGAGGGCAGTGATCAACATGTGGCCTCCCATCTGCCTCTGCA CCCCATAATGCACAACAAACCTCACTCTGAGGAGCTACCAACACTTGTCAGTACCATTCAACAAGATGCT GACTGGGACAGCGTTCTGTCATCTCAGCAAAGAATGGAATCAGAGAATAATAAGTTATGTTCCCTATATT CCTTCCGAAATACCTCTACCTCACCACATAAGCCTGACGAAGGGAGTCGGGACCGTGAGATAATGACCAG TGTTACTTTTGGAACCCCAGAGCGCCGCAAAGGGAGTCTTGCCGATGTGGTGGACACACTGAAACAGAAG AAGCTTGAGGAAATGACTCGGACTGAACAAGAGGATTCCTCCTGCATGGAAAAACTACTTTCAAAAGATT GGAAGGAAAAAATGGAAAGACTAAATACCAGTGAACTTCTTGGAGAAATTAAAGGTACACCTGAGAGCCT GGCAGAAAAAGAACGGCAGCTCTCCACCATGATTACCCAGCTGATCAGTTTACGGGAGCAGCTACTGGCA GCGCATGATGAACAGAAAAAACTGGCAGCGTCACAAATTGAGAAACAACGGCAGCAAATGGACCTTGCTC GCCAACAGCAAGAACAGATTGCGAGACAACAGCAGCAACTTCTGCAACAGCAGCACAAAATTAATCTCCT GCAGCAACAGATCCAGGTTCAGGGTCACATGCCTCCGCTCATGATCCCAATTTTTCCACATGACCAGCGG ACTCTGGCAGCAGCTGCTGCTGCCCAACAGGGATTCCTCTTCCCCCCTGGAATAACATACAAACCAGGTG ATAACTACCCCGTACAGTTCATTCCATCAACAATGGCAGCTGCTGCTGCTTCTGGACTCAGCCCTTTACA GCTCCAGCAGCTCTATGCCGCTCAGCTGGCCAGCATGCAGGTGTCACCTGGAGCAAAGATGCCATCAACT CCACAGCCACCAAACACAGCAGGGACGGTCTCACCTACTGGGATAAAAAATGAAAAGAGAGGGACCAGCC CTGTAACTCAAGTTAAGGATGAAGCAGCAGCACAGCCTCTGAATCTCTCATCCCGACCCAAGACAGCAGA GCCTGTAAAGTCCCCAACGTCTCCCACCCAGAACCTCTTCCCAGCCAGCAAAACCAGCCCTGTCAATCTG CCAAACAAAAGCAGCATCCCTAGCCCCATTGGAGGAAGCCTGGGAAGAGGATCCTCTTTAGGTAAATGGA AAAGTCAACACCAGGAAGAGACTTACGAATTAGATATCCTATCTAGTCTCAACTCCCCTGCCCTTTTTGG GGATCAGGATACAGTGATGAAAGCCATTCAGGAGGCGCGGAAGATGCGAGAGCAGATCCAGCGGGAGCAA CAGCAGCAACAGCCACATGGTGTTGACGGGAAACTGTCCTCCATAAATAATATGGGGCTGAACAGCTGCA GGAATGAAAAGGAAAGAACGCGCTTTGAGAATTTGGGGCCCCAGTTAACGGGAAAGTCAAATGAAGATGG AAAACTGGGCCCAGGTGTCATCGACCTTACTCGGCCAGAAGATGCAGAGGGAAGTAAAGCAATGAATGGC TCTGCAGCTAAACTACAGCAGTATTATTGTTGGCCAACAGGAGGTGCCACTGTGGCTGAAGCACGAGTCT ACAGGGACGCCCGCGGCCGTGCCAGCAGCGAGCCACACATTAAGCGACCAATGAATGCATTCATGGTTTG GGCAAAGGATGAGAGGAGAAAAATCCTTCAGGCCTTCCCCGACATGCATAACTCCAACATTAGCAAAATC TTAGGATCTCGCTGGAAATCAATGTCCAACCAGGAGAAGCAACCTTATTATGAAGAGCAGGCCCGGCTAA GCAAGATCCACTTAGAGAAGTACCCAAACTATAAATACAAACCCCGACCGAAACGCACCTGCATTGTTGA TGGCAAAAAGCTTCGGATTGGGGAGTATAAGCAACTGATGAGGTCTCGGAGACAGGAGATGAGGCAGTTC TTTACTGTGGGGCAACAGCCTCAGATTCCAATCACCACAGGAACAGGTGTTGTGTATCCTGGTGCTATCA CTATGGCAACTACCACACCATCGCCTCAGATGACATCTGACTGCTCTAGCACCTCGGCCAGCCCGGAGCC CAGCCTCCCGGTCATCCAGAGCACTTATGGTATGAAGACAGATGGCGGAAGCCTAGCTGGAAATGAAATG ATCAATGGAGAGGATGAAATGGAAATGTATGATGACTATGAAGATGACCCCAAATCAGACTATAGCAGTG AAAATGAAGCCCCGGAGGCTGTCAGTGCCAACTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_017508 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_017508.1, NP_059978.1 |
| RefSeq Size | 5158 bp |
| RefSeq ORF | 2415 bp |
| Locus ID | 55553 |
| UniProt ID | P35712 |
| Protein Families | Transcription Factors |
| Gene Summary | This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009] Transcript Variant: This variant (1) encodes isoform b. Variants 1 and 3 both encode the same isoform (b). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. CCDS Note: The coding region has been updated to start at a downstream in-frame start codon that is supported by conservation data. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Osteochondral Tissue Regeneration Through Polymeric Delivery of DNA Encoding for the SOX Trio and RUNX2
,Needham, CJ;Shah, SR;Dahlin, RL;Kinard, LA;Lam, J;Watson, BM;Lu, S;Kurtis Kasper, F;Mikos, AG;,
Acta Biomater
,PubMed ID 24854956
[SOX6]
|
|
Development of a Polymeric Gene Delivery Vector for Application in Osteochondral Tissue Engineering
,Needham, CJ;,
Thesis
[SOX6]
|
Documents
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| FAQs |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211525 | SOX6 (Myc-DDK-tagged)-Human SRY (sex determining region Y)-box 6 (SOX6), transcript variant 1 |
CNY 8,832.00 |
|
| RC211525L3 | Lenti ORF clone of Human SRY (sex determining region Y)-box 6 (SOX6), transcript variant 1, Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC211525L4 | Lenti ORF clone of Human SRY (sex determining region Y)-box 6 (SOX6), transcript variant 1, mGFP tagged |
CNY 7,700.00 |
|
| RG211525 | SOX6 (tGFP-tagged) - Human SRY (sex determining region Y)-box 6 (SOX6), transcript variant 1 |
CNY 10,432.00 |
