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EDD (UBR5) (NM_015902) Human Untagged Clone
CAT＃: SC304366
UBR5 (untagged)-Human ubiquitin protein ligase E3 component n-recognin 5 (UBR5)
CNY 26,790.00
货期*
2周
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DD5; EDD; EDD1; HYD |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_015902 edited
ATGACGTCCATCCATTTCGTGGTTCACCCGCTGCCGGGCACCGAGGACCAGCTCAATGAC AGGTTACGAGAAGTTTCTGAGAAGCTGAACAAATATAATTTAAACAGCCACCCCCCTTTG AATGTATTGGAACAGGCTACTATTAAACAGTGTGTGGTGGGACCAAATCATGCTGCCTTT CTTCTTGAGGATGGTAGAGTTTGCAGGATTGGTTTTTCAGTACAGCCAGACAGATTGGAA TTGGGTAAACCTGATAATAATGATGGGTCAAAGTTGAACAGCAACTCGGGGGCAGGGAGG ACGTCAAGGCCTGGTAGGACAAGCGACTCTCCATGGTTTCTCTCAGGTTCTGAGACTCTA GGCAGGCTGGCAGGCAACACCTTAGGAAGCCGCTGGAGTTCTGGAGTGGGTGGAAGTGGT GGAGGATCCTCTGGTAGGTCATCAGCTGGAGCTCGAGATTCCCGCCGGCAGACTCGAGTT ATTCGGACAGGACGGGATCGAGGGTCTGGGCTTTTGGGCAGTCAGCCCCAGCCAGTTATT CCAGCATCTGTCATTCCAGAGGAGCTGATTTCACAGGCCCAAGTTGTTTTACAAGGCAAA TCCAGAAGTGTCATTATTCGAGAACTTCAGAGAACAAATCTTGATGTGAACCTTGCTGTA AATAATTTACTTAGCCGGGATGATGAAGATGGAGATGATGGGGATGATACAGCCAGCGAA TCTTATTTGCCTGGAGAGGATCTTATGTCTCTCCTTGATGCCGACATTCATTCTGCCCAC CCAAGTGTCATTATTGATGCAGATGCCATGTTTTCTGAAGACATTAGCTATTTTGGTTAC CCTTCTTTTCGTCGTTCATCACTTTCCAGGCTAGGCTCATCTCGAGTTCTCCTTCTTCCC TTAGAGAGAGACTCTGAGCTGTTGCGTGAACGTGAATCCGTTTTACGTTTACGTGAACGA AGGTGGCTTGATGGAGCCTCATTTGATAATGAAAGGGGTTCTACCAGCAAGGAAGGAGAG CCAAACTTGGATAAGAAGAATACACCTGTTCAAAGTCCAGTATCTCTAGGAGAAGATTTG CAGTGGTGGCCTGATAAGGATGGAACAAAATTCATCTGTATTGGGGCTCTGTATTCTGAA CTTCTGGCTGTCAGCAGTAAAGGAGAACTTTATCAGTGGAAATGGAGTGAATCTGAGCCT TACAGAAATGCCCAGAATCCTTCATTACATCATCCACGAGCAACATTTTTGGGGTTAACC AATGAAAAGATAGTCCTCCTGTCTGCAAATAGCATAAGAGCAACTGTAGCTACAGAAAAT AACAAGGTTGCTACATGGGTGGATGAAACTTTAAGTTCTGTGGCTTCTAAATTAGAGCAC ACTGCTCAGACTTACTCTGAACTTCAAGGAGAGCGGATAGTTTCTTTACATTGCTGTGCC CTTTACACCTGCGCTCAGCTGGAAAACAGTTTATATTGGTGGGGTGTAGTTCCTTTTAGT CAAAGGAAGAAAATGTTAGAGAAAGCTAGAGCAAAAAATAAAAAGCCTAAATCCAGTGCT GGTATTTCTTCAATGCCGAACATCACTGTTGGTACCCAGGTATGCTTGAGAAATAATCCT CTTTATCATGCTGGAGCAGTTGCATTTTCAATTAGTGCTGGGATTCCTAAAGTTGGTGTC TTAATGGAGTCAGTTTGGAATATGAATGACAGCTGTAGATTTCAACTTAGATCTCCTGAA AGCTTGAAAAACATGGAAAAAGCTAGCAAAACTACTGAAGCTAAGCCTGAAAGTAAGCAG GAGCCAGTGAAAACAGAAATGGGTCCTCCACCATCTCCAGCATCCACGTGTAGTGATGCA TCCTCAATTGCCAGCAGTGCATCAATGCCATACAAACGACGACGGTCAACCCCTGCACCA AAAGAAGAGGAAAAGGTGAATGAAGAGCAGTGGTCTCTTCGGGAAGTGGTTTTTGTGGAA GATGTCAAGAATGTTCCTGTTGGCAAGGTGCTAAAAGTAGATGGTGCCTATGTTGCTGTA AAATTTCCAGGAACCTCCAGTAATACTAACTGTCAGAACAGCTCTGGTCCAGATGCTGAC CCTTCTTCTCTCCTGCAGGATTGTAGGTTACTTAGAATTGATGAATTGCAGGTTGTCAAA ACTGGTGGAACACCGAAGGTTCCCGACTGTTTCCAAAGGACTCCTAAAAAGCTTTGTATA CCTGAAAAAACAGAAATATTAGCAGTGAATGTAGATTCCAAAGGTGTTCATGCTGTTCTG AAGACTGGAAATTGGGTACGATACTGTATCTTTGATCTTGCTACAGGAAAAGCAGAACAG GAAAATAATTTTCCTACAAGCAGCATTGCTTTCCTTGGTCAGAATGAGAGGAATGTAGCC ATTTTCACTGCTGGACAGGAATCTCCCATTATTCTTCGAGATGGAAATGGTACCATCTAC CCAATGGCCAAAGATTGCATGGGAGGAATAAGGGATCCCGATTGGCTGGATCTTCCACCT ATTAGTAGTCTTGGAATGGGTGTGCATTCTTTAATAAATCTTCCTGCCAATTCAACAATC AAAAAGAAAGCTGCTGTTATCATCATGGCTGTAGAGAAACAAACCTTAATGCAACACATT CTGCGCTGTGACTATGAGGCCTGTCGACAATATCTAATGAATCTTGAGCAAGCGGTTGTT TTAGAGCAGAATCTACAGATGCTGCAGACATTCATCAGCCACAGATGTGATGGAAATCGA AATATTTTGCATGCTTGTGTATCAGTTTGCTTTCCAACCAGCAATAAAGAAACTAAAGAA GAAGAGGAAGCGGAGCGTTCTGAAAGAAATACATTTGCAGAAAGGCTTTCTGCTGTTGAG GCCATTGCAAATGCAATATCAGTTGTTTCAAGTAATGGCCCAGGTAATCGGGCTGGATCA TCAAGTAGCCGAAGTTTGAGATTACGGGAAATGATGAGACGTTCGTTGAGAGCAGCTGGT TTGGGTAGACATGAAGCTGGAGCTTCATCCAGTGACCACCAGGATCCAGTTTCACCCCCC ATAGCTCCCCCTAGTTGGGTTCCTGACCCTCCTGCGATGGATCCTGATGGTGACATTGAT TTTATCCTGGCCCCCGCTGTGGGATCTCTTACCACAGCAGCAACCGGTACTGGTCAAGGA CCAAGCACCTCCACTATTCCAGGTCCTTCCACAGAGCCATCTGTAGTAGAATCCAAGGAT CGAAAGGCGAATGCTCATTTTATATTGAAATTGTTATGTGACAGTGTGGTTCTCCAGCCC TATCTACGAGAACTTCTTTCTGCCAAGGATGCAAGAGGGATGACCCCATTTATGTCAGCT GTAAGTGGCCGAGCTTATCCTGCTGCAATTACCATCTTAGAAACTGCTCAGAAAATTGCA AAAGCTGAAATATCCTCAAGTGAAAAAGAGGAAGATGTATTCATGGGAATGGTTTGCCCA TCAGGTACCAACCCTGATGACTCTCCTTTATATGTTTTATGTTGTAATGACACTTGCAGT TTTACATGGACTGGAGCAGAGCACATTAACCAGGATATTTTTGAGTGTCGAACTTGTGGC TTGCTGGAGTCACTGTGTTGTTGTACGGAATGTGCAAGGGTTTGTCATAAAGGTCATGAT TGCAAACTCAAACGGACATCACCAACAGCCTACTGTGATTGTTGGGAGAAATGTAAATGT AAAACTCTTATTGCTGGACAGAAATCTGCTCGTCTTGATCTACTTTATCGCCTGCTCACT GCTACTAATCTGGTTACTCTGCCAAACAGCAGGGGAGAGCACCTCTTACTATTCTTAGTA CAGACAGTCGCAAGGCAGACGGTGGAGCATTGTCAATACAGGCCACCTCGAATCAGGGAA GATCGTAACCGAAAAACAGCCAGTCCTGAAGATTCAGATATGCCAGATCATGATTTAGAG CCTCCAAGATTTGCCCAGCTTGCATTGGAGCGTGTTCTACAGGACTGGAATGCCTTGAAA TCTATGATTATGTTTGGGTCGCAGGAGAATAAAGACCCTCTTAGTGCCAGCAGTAGAATA GGCCATCTTTTGCCAGAAGAGCAAGTATACCTCAATCAGCAAAGTGGCACAATTCGGCTG GACTGTTTCACTCATTGCCTTATAGTTAAGTGTACAGCAGATATTTTGCTTTTAGATACT CTACTAGGTACACTAGTGAAAGAACTCCAAAACAAATATACACCTGGACGTAGAGAAGAA GCTATTGCTGTGACAATGAGGTTTCTACGTTCAGTGGCAAGAGTTTTTGTTATTCTGAGT GTGGAAATGGCTTCATCCAAAAAGAAAAACAACTTTATTCCACAGCCAATTGGAAAATGC AAGCGTGTATTCCAAGCATTGCTACCTTACGCTGTGGAAGAATTGTGCAACGTAGCAGAG TCACTGATTGTTCCTGTCAGAATGGGGATTGCTCGTCCAACTGCACCATTTACCCTGGCT AGTACTAGCATAGATGCCATGCAGGGCAGTGAAGAATTATTTTCAGTGGAACCACTACCA CCACGACCATCATCTGATCAGTCTAGCAGCTCCAGTCAGTCTCAGTCATCCTACATCATC AGGAATCCACAGCAGAGGCGCATCAGCCAGTCACAGCCCGTTCGGGGCAGAGATGAAGAA CAGGATGATATTGTTTCAGCAGATGTGGAAGAGGTTGAGGTGGTGGAGGGTGTGGCTGGA GAAGAGGATCATCATGATGAACAGGAAGAACACGGGGAAGAAAATGCTGAGGCAGAGGGA CAACATGATGAGCATGATGAAGACGGGAGTGATATGGAGCTGGACTTGTTAGCAGCAGCT GAAACAGAAAGTGATAGTGAAAGTAACCACAGCAACCAAGATAATGCTAGTGGGCGCAGA AGCGTTGTCACTGCAGCAACTGCTGGTTCAGAAGCAGGAGCAAGCAGTGTTCCTGCCTTC TTTTCTGAAGATGATTCTCAATCGAATGACTCAAGTGATTCTGATAGCAGTAGTAGTCAG AGTGACGACATAGAACAGGAGACCTTTATGCTTGATGAGCCATTAGAAAGAACCACAAAT AGCTCCCATGCCAATGGTGCTGCCCAAGCTCCCCGTTCAATGCAGTGGGCTGTCCGCAAC ACCCAGCATCAGCGAGCAGCCAGTACAGCCCCTTCCAGTACATCTACACCAGCAGCAAGT TCAGCGGGTTTGATTTATATTGATCCTTCAAACTTACGCCGGAGTGGTACCATCAGTACA AGTGCTGCAGCTGCAGCAGCTGCTTTGGAAGCTAGCAACGCCAGCAGTTACCTAACATCT GCAAGCAGTTTAGCCAGGGCTTACAGCATTGTCATTAGACAAATCTCGGACTTGATGGGC CTTATTCCTAAGTATAATCACCTAGTATACTCTCAGATTCCAGCAGCTGTGAAATTGACT TACCAAGATGCAGTAAACTTACAGAACTATGTAGAAGAAAAGCTTATTCCCACTTGGAAC TGGATGGTCAGTATTATGGATTCTACTGAAGCTCAATTACGTTATGGTTCTGCATTAGCA TCTGCTGGTGATCCTGGACATCCAAATCATCCTCTTCACGCTTCTCAGAATTCAGCGAGA AGAGAGAGGATGACTGCGCGAGAAGAAGCTAGCTTACGAACACTTGAAGGCAGACGACGT GCCACCTTGCTTAGCGCCCGTCAAGGAATGATGTCTGCACGAGGAGACTTCCTAAATTAT GCTCTGTCTCTAATGCGGTCTCATAATGATGAGCATTCTGATGTTCTTCCAGTTTTGGAT GTTTGCTCATTGAAGCATGTGGCATATGTTTTTCAAGCACTTATATACTGGATTAAGGCA ATGAATCAGCAGACAACATTGGATACACCTCAACTAGAACGCAAAAGGACGCGAGAACTC TTGGAACTGGGTATTGATAATGAAGATTCAGAACATGAAAATGATGATGACACCAATCAA AGTGCTACTTTGAATGATAAGGATGATGACTCTCTTCCTGCAGAAACTGGCCAAAACCAT CCATTTTTCCGACGTTCAGACTCCATGACATTCCTTGGGTGTATACCCCCAAATCCATTT GAAGTGCCTCTGGCTGAAGCCATCCCCTTGGCTGATCAGCCACATCTGTTGCAGCCAAAT GCTAGAAAGGAGGATCTTTTTGGCCGTCCAAGTCAGGGTCTTTATTCTTCATCTGCCAGT AGTGGGAAATGTTTAATGGAGGTTACAGTGGATAGAAACTGCCTAGAGGTTCTTCCAACA AAAATGTCTTATGCTGCCAATCTGAAAAATGTAATGAACATGCAAAACCGGCAAAAAAAA GAAGGGGAAGAACAGCCCGTGCTGCCAGAAGAAACTGAGAGTTCAAAACCAGGGCCATCT GCTCATGATCTTGCTGCACAATTAAAAAGTAGCTTACTAGCAGAAATAGGACTTACTGAA AGTGAAGGGCCACCTCTCACATCTTTCAGGCCACAGTGTAGCTTTATGGGAATGGTTATT TCCCATGATATGCTGCTAGGACGTTGGCGCCTTTCTTTAGAACTGTTCGGCAGGGTATTC ATGGAAGATGTTGGAGCAGAACCTGGATCAATCCTAACTGAATTGGGTGGTTTTGAGGTA AAAGAATCAAAATTCCGCAGAGAAATGGAAAAACTGAGAAACCAGCAGTCAAGAGATTTG TCACTAGAGGTTGATCGGGATCGAGATCTTCTCATTCAGCAGACTATGAGGCAGCTTAAC AATCACTTTGGTCGAAGATGTGCTACTACACCAATGGCTGTACACAGAGTAAAAGTCACA TTTAAGGATGAGCCAGGAGAGGGCAGTGGTGTAGCACGAAGTTTTTATACAGCCATTGCA CAAGCATTTTTATCAAATGAAAAATTGCCAAATCTAGAGTGTATCCAAAATGCCAACAAA GGCACCCACACAAGTTTAATGCAGAGATT:AAGGAACCGAGGAGAGAGAGACCGGGAAAG GGAGAGAGAAAGGGAAATGAGGAGGAGTAGTGGTTTGCGAGCAGGTTCTCGGAGGGACCG GGATAGAGACTTTAGAAGACAGCTTTCCATCGACACTAGGCCCTTTAGACCAGCCTCTGA AGGGAATCCTAGCGATGATCCTGAGCCTTTGCCAGCACATCGGCAGGCACTTGGAGAGAG GCTTTATCCTCGTGTACAAGCAATGCAACCAGCATTTGCAAGTAAAATCACTGGCATGTT GTTGGAATTATCCCCAGCTCAGCTGCTTCTCCTTCTAGCAAGTGAGGATTCTCTGAGAGC AAGAGTGGATGAGGCCATGGAACTCATTATTGCACATGGACGGGAAAATGGAGCTGATAG TATCCTGGATCTTGGATTAGTAGACTCCTCAGAAAAGGTACAGCAGGAAAACCGAAAGCG CCATGGCTCTAGTCGAAGTGTAGTAGATATGGATTTAGATGATACAGATGATGGTGATGA CAATGCCCCTTTGTTTTACCAACCTGGGAAAAGAGGATTTTATACTCCAAGGCCTGGCAA GAACACAGAAGCAAGGTTGAATTGTTTCAGAAACATTGGCAGGATTCTTGGACTATGTCT GTTACAGAATGAACTATGTCCTATCACATTGAATAGACATGTAATTAAAGTATTGCTTGG TAGAAAAGTCAATTGGCATGATTTTGCTTTTTTTGATCCTGTAATGTATGAGAGTTTGCG GCAACTAATCCTCGCGTCTCAGAGTTCAGATGCTGATGCTGTTTTCTCAGCAATGGATTT GGCATTTGCAATTGACCTGTGTAAAGAAGAAGGTGGAGGACAGGTTGAACTCATTCCTAA TGGTGTAAATATACCAGTCACTCCACAGAATGTATATGAGTATGTGCGGAAATACGCAGA ACACAGAATGTTGGTAGTTGCAGAACAGCCCTTACATGCAATGAGGAAAGGTCTACTAGA TGTGCTTCCAAAAAATTCATTAGAAGATTTAACGGCAGAAGATTTTAGGCTTTTGGTAAA TGGCTGCGGTGAAGTCAATGTGCAAATGCTGATCAGTTTTACCTCTTTCAATGATGAATC AGGAGAAAATGCTGAGAAGCTTCTGCAGTTCAAGCGTTGGTTCTGGTCAATAGTAGAGAA GATGAGCATGACAGAACGACAAGATCTTGTTTACTTTTGGACATCAAGCCCATCACTGCC AGCCAGTGAAGAAGGATTCCAGCCTATGCCCTCAATCACAATAAGACCACCAGATGACCA ACATCTTCCTACTGCAAATACTTGCATTTCTCGACTTTACGTCCCACTCTATTCCTCTAA ACAGATTCTCAAACAGAAATTGTTACTCGCCATTAAGACCAAGAATTTTGGTTTTGTGTA G |
| Restriction Sites | Please inquire |
| ACCN | NM_015902 |
| Insert Size | 8400 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_015902.4, NP_056986.2 |
| RefSeq Size | 9410 bp |
| RefSeq ORF | 8400 bp |
| Locus ID | 51366 |
| UniProt ID | O95071 |
| Protein Families | Druggable Genome |
| Protein Pathways | Ubiquitin mediated proteolysis |
| Gene Summary | This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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