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LPHN1 (ADGRL1) (NM_014921) Human Untagged Clone
CAT＃: SC304185
LPHN1 (untagged)-Human latrophilin 1 (LPHN1), transcript variant 2
CNY 10,056.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CIRL1; CL1; LEC2; LPHN1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_014921 edited
ATGGCCCGCCTAGCCGCAGTGCTCTGGAATCTGTGTGTCACCGCCGTCCTGGTCACCTCG GCCACCCAAGGCCTGAGCCGGGCCGGGCTCCCGTTCGGGCTGATGCGCCGGGAGCTGGCG TGTGAAGGCTACCCCATCGAGCTGCGGTGCCCCGGCAGCGACGTCATCATGGTGGAGAAT GCCAACTACGGGCGCACGGACGACAAGATTTGCGATGCTGACCCTTTCCAGATGGAGAAT GTGCAGTGCTACCTGCCGGACGCCTTCAAGATCATGTCACAGAGGTGTAACAACCGCACC CAGTGCGTGGTGGTCGCCGGCTCGGATGCCTTTCCTGACCCCTGTCCTGGGACCTACAAG CACCTGGAGGTGCAGTACGACTGTGTCCCCTACATCTTCGTGTGCCCAGGGACCCTGCAG AAGGTGCTGGAGCCCACCTCGACACACGAGTCAGAGCACCAGTCTGGCGCATGGTGCAAG GACCCGCTGCAGGCGGGTGACCGCATCTACGTGATGCCCTGGATCCCCTACCGCACGGAC ACACTGACTGAGTATGCCTCGTGGGAGGACTACGTGGCCGCCCGCCACACCACCACCTAC CGCCTGCCCAACCGCGTGGATGGCACAGGCTTTGTGGTCTACGATGGTGCCGTCTTCTAC AACAAGGAGCGCACGCGCAACATCGTCAAGTATGACCTACGGACGCGCATCAAGAGCGGG GAGACGGTCATCAATACCGCCAACTACCATGACACCTCGCCCTACCGCTGGGGCGGAAAG ACCGACATTGACCTGGCGGTGGACGAGAACGGGCTGTGGGTCATCTACGCCACTGAGGGC AACAACGGGCGGCTGGTGGTGAGCCAGCTGAACCCCTACACACTGCGCTTTGAGGGCACG TGGGAGACGGGTTACGACAAGCGCTCGGCATCCAACGCCTTCATGGTGTGTGGGGTCCTG TACGTCCTGCGTTCCGTGTACGTGGATGATGACAGCGAGGCGGCTGGCAACCGCGTGGAC TATGCCTTCAACACCAATGCCAACCGCGAGGAGCCTGTCAGCCTCACCTTCCCCAACCCC TACCAGTTCATCTCCTCCGTTGACTACAACCCTCGCGACAACCAGCTGTACGTCTGGAAC AACTATTTCGTGGTGCGCTACAGCCTGGAGTTCGGGCCGCCCGACCCCAGTGCTGGCCCA GCCACTTCCCCACCCCTCAGCACGACCACCACAGCCAGGCCCACGCCCCTCACCAGCACA GCCTCGCCCGCAGCCACCACCCCGCTCCGCCGGGCACCCCTCACCACGCACCCAGTGGGT GCCATCAACCAGCTGGGACCTGATCTGCCTCCAGCCACAGCCCCAGTCCCCAGCACCCGG CGGCCCCCAGCCCCGAATCTACACGTGTCCCCTGAGCTCTTCTGCGAGCCCCGAGAGGTA CGGCGGGTCCAGTGGCCGGCCACCCAGCAGGGCATGCTGGTGGAGAGGCCCTGCCCCAAG GGGACTCGAGGAATTGCCTCCTTCCAGTGTCTACCAGCCTTGGGGCTCTGGAACCCCCGG GGCCCTGACCTCAGCAACTGCACCTCCCCCTGGGTCAACCAGGTGGCCCAGAAGATCAAG AGTGGGGAGAACGCGGCCAACATCGCCAGCGAGCTGGCCCGACACACCCGGGGCTCCATC TACGCGGGGGACGTCTCCTCCTCTGTGAAGCTGATGGAGCAGCTGCTGGACATCCTGGAT GCCCAGCTGCAGGCCCTGCGGCCCATCGAGCGCGAGTCAGCCGGCAAGAACTACAACAAG ATGCACAAGCGAGAGAGAACTTGTAAGGATTATATCAAGGCCGTGGTGGAGACAGTGGAC AATCTGCTCCGGCCAGAAGCTCTGGAGTCCTGGAAGGACATGAATGCCACGGAGCAGGTG CACACGGCCACCATGCTCCTCGACGTCCTGGAGGAGGGCGCCTTCCTGCTGGCCGACAAT GTCAGGGAGCCTGCCCGCTTCCTGGCTGCCAAGGAGAACGTGGTCCTGGAGGTCACAGTC CTGAACACAGAGGGCCAGGTGCAGGAGCTGGTGTTCCCCCACGAGGAGTACCCGAGAAAG AACTCCATCCAGCTGTCTGCCAAAACCATCAAGCAGAACAGCCGCAATGGGGTGGTCAAA GTTGTCTTCATCCTCTACAACAACCTGGGCCTCTTCCTGTCCACGGAGAATGCCACAGTG AAGCTGGCCGGCGAAGCAGGCCCGGGTGGCCCTGGGGGCGCCTCTCTAGTGGTGAACTCA CAGGTCATCGCAGCATCCATCAACAAGGAGTCCAGCCGCGTCTTCCTCATGGACCCTGTC ATCTTCACCGTGGCCCACCTGGAGGACAAGAACCACTTCAATGCTAACTGCTCCTTCTGG AACTACTCGGAGCGTTCCATGCTGGGCTACTGGTCGACCCAAGGCTGCCGCCTGGTGGAG TCCAACAAGACCCATACCACGTGTGCCTGCAGCCACCTCACCAACTTCGCTGTGCTCATG GCTCACCGTGAGATCTACCAGGGCCGCATCAACGAGCTGCTGCTGTCGGTCATCACCTGG GTGGGCATTGTGATCTCCCTGGTCTGCTTGGCCATCTGCATCTCCACCTTCTGCTTCCTG CGGGGGCTGCAGACCGACCGCAACACCATCCACAAGAACCTGTGCATCAACCTCTTCCTG GCTGAGCTGCTCTTCCTGGTCGGGATCGACAAGACTCAGTATGAGATTGCCTGCCCCATC TTCGCCGGCCTGCTGCACTATTTCTTCCTGGCTGCCTTCTCCTGGCTGTGCCTGGAGGGC GTGCACCTCTACCTGCTACTAGTGGAGGTGTTTGAGAGCGAGTATTCCCGCACCAAGTAC TACTACCTGGGTGGCTACTGCTTCCCGGCCCTGGTGGTGGGCATCGCGGCTGCCATTGAC TACCGCAGCTACGGCACCGAGAAGGCCTGCTGGCTCCGAGTGGACAATTACTTCATCTGG AGTTTCATCGGGCCAGTCTCCTTCGTTATCGTGGTCAACCTGGTGTTCCTCATGGTGACC CTGCACAAGATGATCCGAAGCTCATCTGTGCTCAAGCCCGACTCCAGCCGCCTGGACAAC ATTAAATCCTGGGCGCTGGGGGCCATCGCGCTGCTGTTCCTGCTGGGCCTCACCTGGGCT TTCGGCCTCCTCTTCATCAACAAGGAGTCGGTGGTCATGGCCTATCTCTTCACCACCTTC AACGCCTTCCAGGGGGTCTTCATCTTCGTCTTTCACTGCGCCTTACAGAAGAAGGTGCAC AAGGAGTACAGCAAGTGCCTGCGTCACTCCTACTGCTGCATCCGCTCCCCACCCGGGGGC ACTCACGGATCCCTCAAGACCTCAGCCATGCGAAGCAACACCCGCTACTACACAGGGACC CAGAGCCGAATTCGGAGGATGTGGAATGACACTGTGAGGAAACAGACGGAGTCCTCCTTC ATGGCGGGTGACATCAACAGCACCCCCACCCTGAACCGAGGTACCATGGGGAACCACCTG CTGACCAACCCCGTGCTGCAGCCCCGTGGGGGCACCAGTCCCTACAACACCCTCATCGCC GAGTCAGTGGGCTTCAATCCCTCCTCGCCCCCTGTCTTCAACTCCCCAGGGAGCTACCGG GAACCCAAGCACCCCTTGGGAGGCCGGGAAGCCTGTGGCATGGACACCCTGCCCCTGAAC GGCAACTTCAATAACAGTTACTCCTTGCGAAGTGGGGATTTCCCTCCCGGGGATGGGGGC CCTGAGCCGCCCCGAGGCCGGAACCTAGCCGATGCGGCGGCCTTTGAGAAGATGATCATC TCAGAGCTGGTGCACAACAACCTGCGGGGGAGCAGCAGCGCGGCCAAGGGCCCTCCACCG CCTGAGCCCCCTGTGCCACCTGTGCCAGGGGGCGGGGGCGAGGAAGAGGCGGGCGGGCCC GGGGGTGCTGACCGGGCCGAGATTGAACTTCTCTATAAGGCCCTGGAGGAGCCTCTGCTG CTGCCCCGGGCCCAGTCGGTGCTGTACCAGAGCGATCTGGACGAGTCGGAGAGCTGCACG GCCGAGGACGGCGCCACCAGCCGGCCCCTCTCCTCCCCTCCTGGCCGGGACTCCCTCTAT GCCAGCGGGGCCAACCTGCGGGACTCACCCTCCTACCCGGACAGCAGCCCTGAGGGGCCC AGTGAGGCCCTGCCCCCACCCCCTCCCGCACCCCCCGGCCCCCCCGAAATCTACTACACC TCGCGCCCGCCAGCCCTGGTGGCCCGGAATCCCCTGCAGGGCTACTACCAGGTGCGGCGT CCTAGCCACGAGGGCTACCTGGCAGCCCCAGGCCTTGAGGGGCCAGGGCCCGATGGGGAC GGGCAGATGCAGCTGGTCACCAGTCTCTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_014921 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_014921.3, NP_055736.2 |
| RefSeq Size | 7871 bp |
| RefSeq ORF | 4410 bp |
| Locus ID | 22859 |
| UniProt ID | O94910 |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008] Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform 2) compared to isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217296 | LPHN1 (Myc-DDK-tagged)-Human latrophilin 1 (LPHN1), transcript variant 2 |
CNY 10,048.00 |
|
| RC217296L3 | Lenti-ORF clone of LPHN1 (Myc-DDK-tagged)-Human latrophilin 1 (LPHN1), transcript variant 2 |
CNY 16,530.00 |
|
| RC217296L4 | Lenti-ORF clone of LPHN1 (mGFP-tagged)-Human latrophilin 1 (LPHN1), transcript variant 2 |
CNY 16,530.00 |
|
| RG217296 | LPHN1 (tGFP-tagged) - Human latrophilin 1 (LPHN1), transcript variant 2 |
CNY 16,060.00 |
