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NRG1 (NM_013962) Human Untagged Clone
CAT＃: SC304024
NRG1 (untagged)-Human neuregulin 1 (NRG1), transcript variant GGF2
CNY 6,750.00
Product images
CNY 1,999.00
CNY 3,600.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; MST131; MSTP131; NDF; NRG1-IT2; SMDF |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_013962 edited
ATGAGATGGCGACGCGCCCCGCGCCGCTCCGGGCGTCCCGGCCCCCGGGCCCAGCGCCCC GGCTCCGCCGCCCGCTCGTCGCCGCCGCTGCCGCTGCTGCCACTACTGCTGCTGCTGGGG ACCGCGGCCCTGGCGCCGGGGGCGGCGGCCGGCAACGAGGCGGCTCCCGCGGGGGCCTCG GTGTGCTACTCGTCCCCGCCCAGCGTGGGATCGGTGCAGGAGCTAGCTCAGCGCGCCGCG GTGGTGATCGAGGGAAAGGTGCACCCGCAGCGGCGGCAGCAGGGGGCACTCGACAGGAAG GCGGCGGCGGCGGCGGGCGAGGCAGGGGCGTGGGGCGGCGATCGCGAGCCGCCAGCCGCG GGCCCACGGGCGCTGGGGCCGCCCGCCGAGGAGCCGCTGCTCGCCGCCAACGGGACCGTG CCCTCTTGGCCCACCGCCCCGGTGCCCAGCGCCGGCGAGCCCGGGGAGGAGGCGCCCTAT CTGGTGAAGGTGCACCAGGTGTGGGCGGTGAAAGCCGGGGGCTTGAAGAAGGACTCGCTG CTCACCGTGCGCCTGGGGACCTGGGGCCACCCCGCCTTCCCCTCCTGCGGGAGGCTCAAG GAGGACAGCAGGTACATCTTCTTCATGGAGCCCGACGCCAACAGCACCAGCCGCGCGCCG GCCGCCTTCCGAGCCTCTTTCCCCCCTCTGGAGACGGGCCGGAACCTCAAGAAGGAGGTC AGCCGGGTGCTGTGCAAGCGGTGCGCCTTGCCTCCCCAATTGAAAGAGATGAAAAGCCAG GAATCGGCTGCAGGTTCCAAACTAGTCCTTCGGTGTGAAACCAGTTCTGAATACTCCTCT CTCAGATTCAAGTGGTTCAAGAATGGGAATGAATTGAATCGAAAAAACAAACCACAAAAT ATCAAGATACAAAAAAAGCCAGGGAAGTCAGAACTTCGCATTAACAAAGCATCACTGGCT GATTCTGGAGAGTATATGTGCAAAGTGATCAGCAAATTAGGAAATGACAGTGCCTCTGCC AATATCACCATCGTGGAATCAAACGCTACATCTACATCCACCACTGGGACAAGCCATCTT GTAAAATGTGCGGAGAAGGAGAAAACTTTCTGTGTGAATGGAGGGGAGTGCTTCATGGTG AAAGACCTTTCAAACCCCTCGAGATACTTGTGCAAGTGCCCAAATGAGTTTACTGGTGAT CGCTGCCAAAACTACGTAATGGCCAGCTTCTACAGTACGTCCACTCCCTTTCTGTCTCTG CCTGAATAG >OriGene 5' read for NM_013962 unedited
GGAGCTTGTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCCCTTAATAAATAAAAGG AGGAGGGCAAGGGGGGAGGAGGAGGAGTGGTGCTGCGAGGGGAAGGAAAAGGGAGGCAGC GCGAGAGAGCCGGGCAGAGTCCGAACCGACAGCCAGAAGCCCGCACGCACCTCGCACCAT GAGATGGCGACGCGCCCCGCGCCGCTCCGGGCGTCCCGGCCCCCGGGCCCAGCGCCCCGG CTCCGCCGCCCGCTCGTCGCCGCCGCTGCCGCTGCTGCCACTACTGCTGCTGCTGGGGAC CGCGGCCCTGGCGCCGGGGGCGGCGGCCGGCAACGAGGCGGCTCCCGCGGGGGCCTCGGT GTGCTACTCGTCCCCGCCCAGCGTGGGATCGGTGCAGGAGCTAGCTCAGCGCGCCGCGGT GGTGATCGAGGGAAAGGTGCACCCGCAGCGGCGGCAGCAGGGGGCACTCGACAGGAAGGC GGCGGCGGCGGCGGGCGAGGCAGGGGCGTGGGGCGGCGATCGCGAGCCGCCAGCCGCGGG CCCACGGGCGCTGGGGCCGCCCGCCGAGGAGCCGCTGCTCGCCGCCAACGGGACCGTGCC CTCTTGGCCCACCGCCCCGGTGCCCAGCGCCGGCGAGCCCGGGGAGGAGGCGCCCTATCT GGTGAAGGTGCACCAGTGTGGGCGGTGAAAGCCGGGGGCTTGAAGAAGACTCGCTGCTCA CCGTGCGCCTGGGGACCTGGGGCCACCCCGCCTTCCCCTCCTGCGGGAGGCTCAAGGAGG ACAGCAGTACATCTTCTTCATGGAGCCTGACGCCACAGCACCAGCCGCGCGCCGGCCGCC TTCGAGCCTCTTTCCCCCTCTGGAGACGGCCCGGAACCTCAAGAAGGAGGTCAGCCGGGT GCTGTGCAGCGGTGCGC |
| Restriction Sites | Please inquire |
| ACCN | NM_013962 |
| Insert Size | 1269 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to differ from the protein associated to this reference by a single amino acid. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_013962.1, NP_039256.1 |
| RefSeq Size | 1986 bp |
| RefSeq ORF | 1269 bp |
| Locus ID | 3084 |
| UniProt ID | Q02297 |
| Protein Families | Druggable Genome, Secreted Protein, Transcription Factors, Transmembrane |
| Protein Pathways | ErbB signaling pathway |
| Gene Summary | The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016] Transcript Variant: This variant (GGF2), which uses the type II promoter, is expressed in the nervous system and functions as a neuronal signal that promotes the proliferation and survival of the oligodendrocyte and the myelinating cell. This variant contains alternate 5' and 3' terminal exons and thus differs in the 5' and 3' coding regions and in both UTRs, and it also lacks two alternate in-frame exons in the central coding region, compared to variant HRG-beta1. The resulting isoform (GGF2, also known as GGFHBS5) has distinct N- and C-termini, lacks an internal segment, and is shorter than isoform HRG-beta1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211372 | NRG1 (Myc-DDK-tagged)-Human neuregulin 1 (NRG1), transcript variant GGF2 |
CNY 3,656.00 |
|
| RC211372L1 | Lenti ORF clone of Human neuregulin 1 (NRG1), transcript variant GGF2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC211372L2 | Lenti ORF clone of Human neuregulin 1 (NRG1), transcript variant GGF2, mGFP tagged |
CNY 5,890.00 |
|
| RC211372L3 | Lenti ORF clone of Human neuregulin 1 (NRG1), transcript variant GGF2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC211372L4 | Lenti ORF clone of Human neuregulin 1 (NRG1), transcript variant GGF2, mGFP tagged |
CNY 5,890.00 |
|
| RG211372 | NRG1 (tGFP-tagged) - Human neuregulin 1 (NRG1), transcript variant GGF2 |
CNY 4,370.00 |
