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AGO1 (NM_012199) Human Untagged Clone
CAT＃: SC303941
AGO1 (untagged)-Human eukaryotic translation initiation factor 2C, 1 (EIF2C1)
CNY 6,288.00
CNY 7,220.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EIF2C; EIF2C1; GERP95; hAgo1; Q99 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_012199 edited
GGTACCTAGGCCCCTCACGCTGGACTTCACAGTCTCCGGGCCGCCTGACCTCCGCACGGG TATATGGGATGGAAGCGGGACCCTCGGGAGCAGCTGCGGGCGCTTACCTGCCCCCCCTGC AGCAGGTGTTCCAGGCACCTCGCCGGCCTGGCATTGGCACTGTGGGGAAACCAATCAAGC TCCTGGCCAATTACTTTGAGGTGGACATCCCTAAGATCGACGTGTACCACTACGAGGTGG ACATCAAGCCGGATAAGTGTCCCCGTAGAGTCAACCGGGAAGTGGTGGAATACATGGTCC AGCATTTCAAGCCTCAGATCTTTGGTGATCGCAAGCCTGTGTATGATGGAAAGAAGAACA TTTACACTGTCACAGCACTGCCCATTGGCAACGAACGGGTCGACTTTGAGGTGACAATCC CTGGGGAAGGGAAGGATCGAATCTTTAAGGTCTCCATCAAGTGGCTAGCCATTGTGAGCT GGCGAATGCTGCATGAGGCCCTGGTCAGCGGCCAGATCCCTGTTCCCTTGGAGTCTGTGC AAGCCCTGGATGTGGCCATGAGGCACCTGGCATCCATGAGGTACACCCCTGTGGGCCGCT CCTTCTTCTCACCGCCTGAGGGCTACTACCACCCGCTGGGGGGTGGGCGCGAGGTCTGGT TCGGCTTTCACCAGTCTGTGCGCCCTGCCATGTGGAAGATGATGCTCAACATTGATGTCT CAGCCACTGCCTTTTATAAGGCACAGCCAGTGATTGAGTTCATGTGTGAGGTGCTGGACA TCAGGAACATAAATGAGCAGCCCAAGCCCCTCACGGACTCTCAGCGCGTTCGCTTCACCA AGGAGATCAAGGGCCTGAAGGTGGAAGTCACCCACTGTGGACAGATGAAGAGGAAGTACC GCGTGTGTAATGTTACCCGTCGCCCTGCTAGCCATCAGACATTCCCCTTACAGCTGGAGA GTGGACAGACTGTGGAGTGCACAGTGGCACAGTATTTCAAGCAGAAATATAACCTTCAGC TCAAGTATCCCCATCTGCCCTGCCTACAAGTTGGCCAGGAACAAAAGCATACCTACCTTC CCCTAGAGGTCTGTAACATTGTGGCTGGGCAGCGCTGTATTAAAAAGCTGACCGACAACC AGACCTCGACCATGATAAAGGCCACAGCTAGATCCGCTCCAGACAGACAGGAGGAGATCA GTCGCCTGATGAAGAATGCCAGCTACAACTTAGATCCCTACATCCAGGAATTTGGGATCA AAGTGAAGGATGACATGACGGAGGTGACAGGGCGAGTGCTGCCGGCGCCCATCTTGCAGT ACGGCGGCCGGAACCGGGCCATTGCCACACCCAATCAGGGTGTCTGGGACATGCGGGGGA AACAGTTCTACAATGGGATTGAGATCAAAGTCTGGGCCATCGCCTGCTTCGCACCCCAAA AACAGTGTCGAGAAGAGGTGCTCAAGAACTTCACAGACCAGCTGCGGAAGATTTCCAAGG ATGCGGGGATGCCTATCCAGGGTCAACCTTGTTTCTGCAAATATGCACAGGGGGCAGACA GCGTGGAGCCTATGTTCCGGCATCTCAAGAACACCTACTCAGGGCTGCAGCTCATTATTG TCATCCTGCCAGGGAAGACGCCGGTGTATGCTGAGGTGAAACGTGTCGGAGATACACTCT TGGGAATGGCTACGCAGTGTGTGCAGGTGAAGAACGTGGTCAAGACCTCACCTCAGACTC TGTCCAACCTCTGCCTCAAGATCAATGTCAAACTTGGTGGCATTAACAACATCCTAGTCC CACACCAGCGCTCTGCCGTTTTTCAACAGCCAGTGATATTCCTGGGAGCAGATGTTACAC ACCCCCCAGCAGGGGATGGGAAAAAACCTTCTATCACAGCAGTGGTAGGCAGTATGGATG CCCACCCCAGCCGATACTGTGCTACTGTGCGGGTACAGCGACCACGGCAAGAGATCATTG AAGACTTGTCCTACATGGTGCGTGAGCTCCTCATCCAATTCTACAAGTCCACCCGTTTCA AGCCTACCCGCATCATCTTCTACCGAGATGGGGTGCCTGAAGGCCAGCTACCCCAGATAC TCCACTATGAGCTACTGGCCATTCGTGATGCCTGCATCAAACTGGAAAAGGACTACCAGC CTGGGATCACTTATATTGTGGTGCAGAAACGCCATCACACCCGCCTTTTCTGTGCTGACA AGAATGAGCGAATTGGGAAGAGTGGTAACATCCCAGCTGGGACCACAGTGGACACCAACA TCACCCACCCATTTGAGTTTGACTTCTATCTGTGCAGCCACGCAGGCATCCAGGGCACCA GCCGACCATCCCATTACTATGTTCTTTGGGATGACAACCGTTTCACAGCAGATGAGCTCC AGATCCTGACGTACCAGCTGTGCCACACTTACGTACGATGCACACGCTCTGTCTCTATCC CAGCACCTGCCTACTATGCCCGCCTGGTGGCTTTCCGGGCACGATACCACCTGGTGGACA AGGAGCATGACAGTGGAGAGGGGAGCCACATATCGGGGCAGAGCAATGGGCGGGACCCCC AGGCCCTGGCCAAAGCCGTGCAGGTTCACCAGGATACTCTGCGCACCATGTACTTCGCTT GAAGGCAGAACGCTGTTACCTCACTGGATAGAAGAAAGCTTTCCAAGCCCCAGGAGCTGT GCCACCCAAATCCAGAGGAAGCAAGGAGGAGGGAGGTGGGGTAGGGAGGAGTGTAGGATG CCTTGTTTCCTTCTATAGAGGTGGTGTAAGAGTGGGGAACAGGGCCAGCAAGACAGACCA CCAGCCAGAAATCTCTGATATCAACCTCATGTCCCCCACCCCTCACCCCATCTTGTCACA TCTGGCCCTGACCCCACTGGACCAAAAGGGGCAGCACTGGTGCCCACCATACACACAGGT GTCTCATGTGACTCACAGTGCTAAAGACTCATGCTTGACAGCTTGGTAAGGTCAACTCTG TAGCCCTGCAGACAAAAGCTGGTTAGGTTTGGGTTTGATACTTTAGATGGGAAAGTGAGG GGCTTGAGAAAGTGGGTGGGAGGAGGGAAGGATTTTTTAGGAGCCTTAATCAGAAAAGGA CTAGATTTGTTTAAGAAGAAAAATGAAACCAGACCCAGATCAATATTTTAGGATACTAGA TGTTTTAATGGGTTCAGAATCCAGTTTGTAGGAAGATTTTTTAATGGTTTTGGTTGCTCC TCCCCCAGCTGCCACCCCCCACCTTACCCTTATTCCTCTCTGTCCACATTTTCTGCCCCA CCTTACTTCTCCTCCCTGACAGACATCCAGCCCCTAGTAATACTTAAGGCACTATGGCAC TTAGCTTTGAAGTGACACGACCCTGTCTTCCTTCCGCCCGCTGGTGGGTAACCAGTGCCT TCCCTGTAACGGTAATGCTGCAGAACTGCAACCTTTTGTACCTTTCTTTGGGGAATGGGG TGGGGGTGGGAGAGGAGGTAGATGGGGAAGAAATACCCCAGACCCAACAAACCTCCAGCC AGAAAGCCAGCTATTTTGCATTTGAAGGAATTGACTTCCTCATTCATTGAGCTTTTTAAA AGATCACAACCTCAAGATGGTTAAAATCCATTGACATTTGCACTTTCAAACATGACAAGT CTCGGAGCTGCTGAGATGACAGGCCCCTGGCCTTTCCACTTATGCCTCCTTTTCTCCTTA TTCCTCCTACCTCCCGCCCCGCCCAGGTCTGGAGTTACTTTCATAGCATTTTTCACTCTT GGCTTCTTTTCTCCCTTGATGGTCAAGTCTCTTATGTTTCAATATTTCTTAACTGGGGTG TCTTATAACAAAAAACTCTTAGGTCTAAAATGAGAAAAAAGAGAGAAAACAAAATGTTAT TTTTATACCATAACTTGAGTGTATTGCCAAAATTTGGAAATCCTTCCCATGCCTGATGAG TTTATATCCCAGAAACATTGAGCCATCAGAACGAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_012199 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | ORF matches with NM_012199.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_012199.2, NP_036331.1 |
| RefSeq Size | 7478 bp |
| RefSeq ORF | 2574 bp |
| Locus ID | 26523 |
| UniProt ID | Q9UL18 |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon. [provided by RefSeq, Nov 2015] Transcript Variant: This variant (1) represents the predominant transcript and encodes two isoforms, which result from the use of alternative in-frame translation termination codons. The shorter isoform (1) results from translation termination at the upstream UGA stop codon, while the longer isoform (1x) results from UGA stop codon readthrough to the downstream UAG termination codon. This RefSeq represents the shorter isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209163 | AGO1 (Myc-DDK-tagged)-Human eukaryotic translation initiation factor 2C, 1 (EIF2C1) |
CNY 6,280.00 |
|
| RC209163L1 | Lenti ORF clone of Human eukaryotic translation initiation factor 2C, 1 (EIF2C1), Myc-DDK-tagged |
CNY 8,680.00 |
|
| RC209163L2 | Lenti ORF clone of Human eukaryotic translation initiation factor 2C, 1 (EIF2C1), mGFP tagged |
CNY 5,890.00 |
|
| RC209163L3 | Lenti ORF clone of Human eukaryotic translation initiation factor 2C, 1 (EIF2C1), Myc-DDK-tagged |
CNY 8,680.00 |
|
| RC209163L4 | Lenti ORF clone of Human eukaryotic translation initiation factor 2C, 1 (EIF2C1), mGFP tagged |
CNY 8,680.00 |
|
| RG209163 | AGO1 (tGFP-tagged) - Human eukaryotic translation initiation factor 2C, 1 (EIF2C1) |
CNY 7,880.00 |
