PLCD1 (NM_006225) Human Untagged Clone
CAT#: SC303752
PLCD1 (untagged)-Human phospholipase C, delta 1 (PLCD1), transcript variant 2
CNY 5,544.00
CNY 7,220.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | NDNC3; PLC-III |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_006225 edited
CCGCACTCCGCTCGGACCCCAGGCCGCCGGTGCTGTCGCTACTCAAGTGAGTCCCGCGGT GCCCCTCCCGCCGCGCCGCCCGTCGGGCATGGACTCGGGCCGGGACTTCCTGACCCTGCA CGGCCTACAGGATGATGAGGATCTACAGGCGCTGCTGAAGGGCAGCCAGCTCCTGAAGGT GAAGTCCAGCTCATGGAGGAGAGAGCGCTTCTACAAGTTGCAGGAGGACTGCAAGACCAT CTGGCAGGAGTCCCGCAAGGTCATGCGGACCCCGGAGTCCCAGCTGTTCTCCATCGAGGA CATTCAGGAGGTGCGAATGGGGCACCGCACGGAGGGTCTGGAGAAGTTCGCCCGTGATGT GCCCGAGGACCGCTGCTTCTCCATTGTCTTCAAGGACCAGCGCAATACACTAGACCTCAT CGCCCCATCGCCAGCTGATGCCCAGCACTGGGTGCTGGGGCTGCACAAGATCATCCACCA CTCAGGCTCCATGGACCAGCGTCAGAAGCTACAGCACTGGATTCACTCCTGCTTGCGAAA AGCTGACAAAAACAAGGACAACAAGATGAGCTTCAAGGAGCTGCAGAACTTCCTGAAGGA GCTCAACATCCAGGTGGACGACAGCTATGCCCGGAAGATCTTCAGGGAGTGTGACCACTC CCAGACAGACTCCCTGGAGGACGAGGAGATTGAGGCCTTCTACAAGATGCTGACCCAGCG GGTGGAGATCGACCGCACCTTCGCCGAGGCCGCGGGCTCAGGGGAGACTCTGTCGGTGGA TCAGTTAGTGACGTTCCTGCAGCACCAGCAGCGGGAGGAGGCGGCAGGGCCTGCGCTGGC CCTCTCCCTCATTGAGCGCTACGAGCCCAGCGAGACTGCCAAGGCGCAGCGGCAGATGAC CAAGGACGGCTTCCTCATGTACTTACTGTCGGCTGACGGCAGCGCCTTCAGCCTGGCACA CCGCCGTGTCTACCAGGACATGGGCCAGCCACTTAGCCACTACCTGGTGTCCTCTTCACA CAACACCTACCTGCTGGAGGACCAGCTAGCCGGGCCCAGCAGCACTGAAGCCTACATCCG GGCACTGTGCAAAGGCTGCCGATGCCTGGAGCTTGACTGCTGGGACGGGCCCAACCAGGA ACCAATCATCTACCACGGCTATACTTTCACTTCCAAGATCCTCTTCTGCGATGTGCTCAG GGCCATCCGGGACTATGCCTTCAAGGCGTCCCCCTACCCTGTCATCCTATCCCTGGAGAA CCACTGCACACTGGAGCAGCAGCGCGTGATGGCGCGGCACCTGCATGCCATCCTGGGCCC CATGCTGTTGAACCGACCACTGGATGGGGTCACCAACAGCCTGCCCTCCCCTGAGCAACT GAAGGGGAAGATCCTGCTGAAGGGGAAGAAGCTCGGGGGGCTCCTGCCCCCTGGAGGGGA GGGTGGCCCTGAGGCCACTGTGGTGTCAGACGAAGACGAGGCTGCTGAGATGGAGGATGA GGCAGTGAGGAGCCGTGTGCAGCACAAGCCCAAGGAGGACAAGCTCAGGCTAGCACAGGA GCTCTCTGACATGGTCATTTACTGCAAGAGTGTCCACTTTGGGGGCTTCTCCAGTCCTGG CACCCCTGGACAGGCCTTCTACGAGATGGCGTCCTTCTCTGAGAACCGTGCCCTTCGACT GCTCCAAGAATCAGGAAACGGCTTTGTCCGCCACAACGTGGGGCACCTGAGCAGAATCTA CCCGGCTGGATGGAGAACAGACTCCTCCAACTACAGCCCCGTGGAGATGTGGAATGGGGG CTGCCAGATCGTGGCCCTGAATTTCCAGACACCTGGGCCAGAGATGGACGTGTACCAGGG CCGCTTCCAGGACAACGGGGCCTGTGGGTACGTGCTGAAGCCCGCCTTCCTGCGAGACCC CAACGGCACCTTTAACCCCCGCGCCCTGGCTCAGGGGCCCTGGTGGGCACGGAAGCGGCT CAACATCAGGGTCATTTCGGGGCAGCAGCTGCCAAAAGTCAACAAGAATAAGAATTCAAT TGTGGACCCCAAAGTGACAGTGGAGATCCATGGCGTGAGCCGGGACGTGGCCAGCCGCCA GACTGCTGTCATCACCAACAATGGTTTCAACCCATGGTGGGACACGGAGTTTGCGTTTGA GGTAGTTGTGCCTGACCTTGCCCTCATCCGCTTCTTGGTGGAAGATTATGATGCCTCCTC CAAGAATGACTTCATTGGCCAGAGTACCATCCCCTTGAACAGCCTCAAGCAAGGATACCG CCATGTCCACCTCATGTCTAAGAACGGGGACCAGCATCCATCAGCCACCCTCTTTGTGAA GATCTCCCTCCAGGACTAGGCTGGAGGAAGCCAGTGGGGTCCCCCCTGAGTGGGCTGGGC CCTCTGTCCACATGTGGGGACAGGGCTGGTGTGGCTGCTCCCAGCCTCTTGCTCAGAGCT AGGCCCCCAAATTGCCTTCAGCCCTAACATAGTGTCTGCTGCTGCCTCCCTGGGGACCAG GAGCTAGCCCAGTCCCTGGAGCTGTCCTTCATTCCGTTAGGAATAACACTGCAGCCCTCT CCACCCTCCGGCCAGCGAGTGGTCAAGGATTTTTATAAAAATCACGATAAGATTAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
Restriction Sites | NotI-NotI |
ACCN | NM_006225 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_006225.1, NP_006216.1 |
RefSeq Size | 2627 bp |
RefSeq ORF | 2271 bp |
Locus ID | 5333 |
UniProt ID | P51178 |
Protein Families | Druggable Genome |
Protein Pathways | Calcium signaling pathway, Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system |
Gene Summary | This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] Transcript Variant: This variant (2) contains an alternate 5' terminal exon compared to transcript variant 1, and initiates translation from an in-frame upstream AUG, resulting in a shorter isoform (2) with a different N-terminus compared to isoform 1. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC208263 | PLCD1 (Myc-DDK-tagged)-Human phospholipase C, delta 1 (PLCD1), transcript variant 2 |
CNY 5,536.00 |
|
RC208263L3 | Lenti ORF clone of Human phospholipase C, delta 1 (PLCD1), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC208263L4 | Lenti ORF clone of Human phospholipase C, delta 1 (PLCD1), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
RG208263 | PLCD1 (tGFP-tagged) - Human phospholipase C, delta 1 (PLCD1), transcript variant 2 |
CNY 7,136.00 |