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Laminin (LAMC3) (NM_006059) Human Untagged Clone
CAT＃: SC303727
LAMC3 (untagged)-Human laminin, gamma 3 (LAMC3)
CNY 30,400.00
货期*
4周
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | OCCM |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC303727 representing NM_006059.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCGGCGGCTGCGCTTCTGCTGGGGCTGGCGCTGCTGGCACCGCGGGCGGCCGGCGCGGGCATGGGC GCGTGCTATGACGGCGCAGGGCGCCCGCAGCGCTGCCTGCCGGTGTTCGAGAACGCGGCGTTTGGGCGG CTCGCCCAGGCCTCGCACACGTGCGGCAGCCCGCCCGAGGACTTCTGTCCCCACGTGGGCGCCGCGGGC GCGGGGGCTCATTGCCAGCGCTGCGACGCCGCCGACCCCCAGCGCCACCACAACGCCTCCTACCTCACC GACTTCCACAGCCAGGACGAGAGCACCTGGTGGCAGAGCCCGTCCATGGCCTTCGGCGTGCAGTACCCC ACCTCGGTCAACATCACCCTCCGCCTAGGGAAGGCTTATGAGATCACGTATGTGAGGCTGAAGTTCCAC ACCAGTCGCCCTGAGAGCTTTGCCATCTACAAGCGCAGCCGCGCCGACGGCCCATGGGAGCCCTACCAG TTCTACAGCGCCTCCTGCCAGAAGACCTACGGCCGGCCCGAGGGCCAGTACCTGCGCCCCGGCGAGGAC GAGCGCGTGGCCTTCTGCACCTCTGAGTTCAGCGACATCTCCCCGCTGAGTGGCGGCAACGTGGCCTTC TCCACCCTGGAGGGCCGGCCCAGCGCCTACAACTTCGAGGAGAGCCCTGGGCTGCAGGAGTGGGTCACC AGCACCGAACTCCTCATCTCTCTAGACCGGCTCAACACGTTTGGGGACGACATCTTCAAGGACCCCAAG GTGCTCCAGTCCTACTATTATGCCGTGTCCGACTTCTCTGTGGGCGGCAGGTGCAAGTGCAACGGGCAT GCCAGCGAGTGCGGCCCCGACGTGGCAGGCCAGTTGGCCTGCCGGTGCCAGCACAACACCACCGGCACA GACTGTGAGCGCTGCCTGCCCTTCTTCCAGGACCGCCCGTGGGCCCGGGGCACCGCCGAGGCTGCCCAC GAGTGTCTGCCCTGCAACTGCAGTGGCCGCTCCGAGGAATGCACGTTTGATCGGGAGCTCTTCCGCAGC ACAGGCCACGGCGGGCGCTGTCACCACTGCCGTGACCACACAGCTGGGCCACACTGTGAGCGCTGTCAG GAGAATTTCTATCACTGGGACCCGCGGATGCCATGCCAGCCCTGTGACTGCCAGTCGGCAGGCTCCCTA CACCTCCAGTGCGATGACACAGGCACCTGCGCCTGCAAGCCCACGGTGACTGGCTGGAAGTGTGACCGC TGTCTGCCCGGGTTCCACTCGCTCAGTGAGGGAGGCTGCAGACCCTGCACTTGCAATCCCGCTGGCAGC CTGGACACCTGTGACCCCCGCAGTGGGCGCTGCCCCTGCAAAGAGAATGTGGAAGGCAACCTATGTGAC AGATGTCGCCCGGGGACCTTTAACCTGCAGCCCCACAATCCAGCTGGCTGCAGCAGCTGTTTCTGCTAT GGCCACTCCAAGGTGTGCGCGTCCACTGCCCAGTTCCAGGTGCATCACATCCTCAGCGATTTCCACCAG GGAGCCGAAGGCTGGTGGGCCAGAAGTGTGGGGGGCTCTGAGCACCCCCCACAATGGAGCCCAAATGGG GTCCTCCTGAGCCCAGAAGACGAGGAGGAGCTCACAGCACCAGAGAAGTTCCTGGGAGACCAGCGGTTC AGCTATGGGCAGCCCCTCATACTGACCTTCCGGGTGCCCCCCGGGGACTCCCCACTCCCTGTACAGCTG AGGCTGGAAGGGACAGGCTTGGCCCTGTCCCTGAGGCACTCTAGCCTGTCTGGCCCCCAGGATGCCGGG CATCCCAGGGAGGTAGAGCTCAGGTTCCACCTGCAGGAGACCTCCGAGGACGTGGCCCCTCCACTGCCC CCCTTCCACTTCCAGCGGCTCCTCGCCAACCTGACCAGCCTCCGCCTCCGCGTCAGTCCCGGCCCCAGC CCTGCCGGTCCAGTGTTCCTGACTGAGGTCCGGCTCACATCCGCCCGGCCAGGGCTTTCCCCGCCAGCC TCCTGGGTGGAGATTTGTTCATGTCCCACTGGCTACACGGGCCAGTTCTGTGAATCCTGTGCTCCGGGA TACAAGAGGGAGATGCCACAGGGGGGTCCCTATGCCAGCTGTGTCCCCTGCACCTGTAACCAGCATGGC ACCTGTGACCCCAACACAGGGATCTGTGTCTGCAGCCACCATACCGAGGGCCCATCCTGTGAACGCTGT TTGCCAGGTTTCTATGGCAACCCTTTCGCGGGCCAAGCCGACGACTGCCAGCCCTGTCCCTGCCCTGGC CAGTCGGCCTGTACGACCATCCCAGAGAGCCGGGAGGTGGTGTGTACCCACTGCCCCCCGGGCCAGAGA GGGCGGCGCTGTGAGGTCTGTGATGATGGCTTTTTTGGGGACCCGCTGGGGCTCTTTGGGCACCCCCAG CCCTGCCACCAGTGCCAGTGTAGCGGGAACGTGGACCCCAATGCCGTGGGCAACTGTGACCCCCTGTCT GGCCACTGCCTGCGCTGCCTGCACAACACCACGGGTGACCACTGTGAGCACTGTCAGGAAGGCTTCTAC GGGAGCGCCCTGGCCCCTCGACCCGCAGACAAATGCATGCCTTGCAGCTGTCACCCACAGGGCTCGGTC AGTGAGCAGATGCCCTGCGACCCAGTGACAGGCCAATGCTCCTGCCTGCCTCATGTGACTGCACGGGAC TGCAGCCGCTGCTACCCTGGCTTCTTCGACCTCCAGCCTGGGAGGGGCTGCCGGAGCTGCAAGTGTCAC CCACTGGGCTCCCAGGAGGACCAGTGCCATCCCAAGACTGGACAGTGCACCTGCCGCCCAGGTGTCACA GGCCAGGCCTGTGACAGGTGCCAGCTGGGTTTCTTCGGCTTCTCCATCAAGGGCTGCCGGGCCTGCAGG TGCTCCCCACTGGGCGCTGCCTCGGCCCAGTGCCACGAGAACGGCACATGCGTGTGCAGGCCTGGCTTC GAGGGCTACAAATGTGACCGCTGCCACGACAACTTCTTCCTCACGGCAGACGGCACACACTGCCAGCAA TGTCCGTCCTGCTACGCCCTGGTGAAGGAGGAGGCAGCCAAGCTGAAGGCCAGACTGACTTTGACGGAG GGGTGGCTCCAAGGGTCCGACTGTGGCAGTCCCTGGGGACCACTAGACATTCTGCTGGGAGAGGCCCCA AGGGGGGACGTCTACCAGGGCCATCACCTGCTTCCAGGGGCTCGGGAAGCCTTCCTGGAGCAGATGATG AGCCTCGAGGGTGCTGTCAAGGCCGCCCGGGAGCAGCTGCAGAGGCTGAACAAGGGTGCCCGCTGTGCC CAGGCCGGATCCCAGAAGACCTGCACCCAGCTGGCAGACCTGGAGGCAGTGCTGGAGTCCTCGGAAGAG GAGATTCTGCATGCAGCTGCCATTCTCGCGTCTCTGGAGATTCCTCAGGAAGGTCCCAGTCAGCCGACC AAATGGAGCCACCTGGCCACAGAGGCCCGTGCCCTCGCCAGGAGCCACAGAGACACCGCCACCAAGATC GCAGCCACTGCTTGGAGGGCCCTGCTCGCCTCCAACACCAGCTACGCGCTTCTCTGGAATCTGCTGGAG GGAAGGGTGGCCCTAGAGACCCAGCGGGACCTGGAGGACAGGTACCAGGAGGTCCAGGCGGCCCAGAAA GCACTGAGGACGGCTGTGGCAGAGGTGCTGCCTGAAGCGGAAAGCGTGTTGGCCACCGTGCAGCAAGTT GGCGCAGATACAGCCCCGTACCTGGCCTTGCTGGCTTCCCCGGGAGCTCTGCCTCAGAAGTCCCGGGCT GAAGACCTGGGCCTGAAGGCGAAGGCCCTGGAGAAGACAGTTGCATCATGGCAGCACATGGCCACTGAG GCTGCCCGAACCCTCCAGACTGCTGCCCAGGCGACGCTACGGCAAACAGAACCCCTCACAAAGCTGCAC CAGGAGGCCAGAGCCGCCCTGACCCAGGCTTCCTCATCTGTCCAGGCTGCGACAGTGACTGTCATGGGA GCCAGGACTCTGCTGGCTGATCTGGAAGGAATGAAGCTGCAGTTTCCCCGGCCCAAGGACCAGGCGGCA TTGCAGAGGAAGGCAGACTCCGTCAGTGACAGACTCCTTGCAGACACGAGAAAGAAGACCAAGCAGGCG GAGAGGATGCTGGGAAACGCGGCCCCTCTTTCCTCCAGTGCCAAGAAGAAGGGCAGAGAAGCAGAGGTG TTGGCCAAGGACAGTGCCAAGCTTGCCAAGGCCTTGCTGAGGGAGCGGAAACAGGCGCACCGCCGTGCC AGCAGGCTCACCAGCCAGACGCAAGCCACGCTCCAACAGGCGTCCCAGCAGGTGCTGGCGTCTGAAGCA CGCAGACAGGAGCTGGAGGAAGCTGAGCGGGTGGGTGCTGGGCTGAGCGAGATGGAGCAGCAGATCCGG GAATCGCGTATCTCACTGGAGAAGGACATCGAGACCTTGTCAGAGCTGCTTGCCAGGCTGGGGTCGCTG GACACCCATCAAGCCCCAGCCCAGGCCCTGAACGAGACTCAGTGGGCACTAGAACGCCTGAGGCTGCAG CTGGGCTCCCCGGGGTCCTTGCAGAGGAAACTCAGTCTGCTGGAGCAGGAATCCCAGCAGCAGGAGCTG CAGATCCAGGGCTTCGAGAGTGACCTCGCCGAGATCCGCGCCGACAAACAGAACCTGGAGGCCATTCTG CACAGCCTGCCCGAGAACTGTGCCAGCTGGCAGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_006059 |
| Insert Size | 4728 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006059.3 |
| RefSeq Size | 6107 bp |
| RefSeq ORF | 4728 bp |
| Locus ID | 10319 |
| UniProt ID | Q9Y6N6 |
| Protein Pathways | ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer |
| MW | 171.2 kDa |
| Gene Summary | Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 3. The gamma 3 chain is most similar to the gamma 1 chain, and contains all the 6 domains expected of the gamma chain. It is a component of laminin 12. The gamma 3 chain is broadly expressed in skin, heart, lung, and the reproductive tracts. In skin, it is seen within the basement membrane of the dermal-epidermal junction at points of nerve penetration. Gamma 3 is also a prominent element of the apical surface of ciliated epithelial cells of lung, oviduct, epididymis, ductus deferens, and seminiferous tubules. The distribution of gamma 3-containing laminins along ciliated epithelial surfaces suggests that the apical laminins are important in the morphogenesis and structural stability of the ciliated processes of these cells. [provided by RefSeq, Aug 2011] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218146 | LAMC3 (Myc-DDK-tagged)-Human laminin, gamma 3 (LAMC3) |
CNY 10,776.00 |
|
| RC218146L3 | Lenti ORF clone of Human laminin, gamma 3 (LAMC3), Myc-DDK-tagged |
CNY 17,580.00 |
|
| RC218146L4 | Lenti ORF clone of Human laminin, gamma 3 (LAMC3), mGFP tagged |
CNY 17,580.00 |
|
| RG218146 | LAMC3 (tGFP-tagged) - Human laminin, gamma 3 (LAMC3) |
CNY 17,290.00 |
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