Integrin alpha 3 (ITGA3) (NM_005501) Human Untagged Clone
CAT#: SC303656
ITGA3 (untagged)-Human integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) (ITGA3), transcript variant b
CNY 7,432.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CD49C; GAP-B3; GAPB3; ILNEB; MSK18; VCA-2; VL3A; VLA3a |
Vector | pCMV6-XL6 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>SC303656 representing NM_005501.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCGGCCGCGAATTCGGCACGAGGGAAGCCGGGATCGAAGGCGACAGCGCGGCCAAGGGGGCGCGGCCGG GACAAGCTGGGGGCCGGTTGCCCGGGGCAGGGACGGCGGCGACCCGGCCGCTGGGGAGGCAGGAAGATA GACCCACGGATCTTAGGAAGGGATCCGAGAGCGCAGCTGTGAAACTGGCTGGGGCTGGGGGCACGAAAC CGATCAGCGCTACGGAGCGCAGCGGCCGGCGGGTTCCAGTGTCCTCCGGCGGCGCGGGGAGCAGGTGAA CAGGTCCTCACGCCCAGCTCCGCGCCCTCACGCGCTCTCGCCGGGACCCCGCTTCCGCTGGCAGCCATG GGCCCCGGCCCCAGCCGCGCGCCCCGCGCCCCACGCCTGATGCTCTGTGCGCTCGCCTTGATGGTGGCG GCCGGCGGCTGCGTCGTCTCCGCCTTCAACCTGGATACCCGATTCCTGGTAGTGAAGGAGGCCGGGAAC CCGGGCAGCCTCTTCGGCTACTCGGTCGCCCTCCATCGGCAGACAGAGCGGCAGCAGCGCTACCTGCTC CTGGCTGGTGCCCCCCGGGAGCTCGCTGTGCCCGATGGCTACACCAACCGGACTGGTGCTGTGTACCTG TGCCCACTCACTGCCCACAAGGATGACTGTGAGCGGATGAACATCACAGTGAAAAATGACCCTGGCCAT CACATTATTGAGGACATGTGGCTTGGAGTGACTGTGGCCAGCCAGGGCCCTGCAGGCAGAGTTCTGGTC TGTGCCCACCGCTACACCCAGGTGCTGTGGTCAGGGTCAGAAGACCAGCGGCGCATGGTGGGCAAGTGC TACGTGCGAGGCAATGACCTAGAGCTGGACTCCAGTGATGACTGGCAGACCTACCACAACGAGATGTGC AATAGCAACACAGACTACCTGGAGACGGGCATGTGCCAGCTGGGCACCAGCGGTGGCTTCACCCAGAAC ACTGTGTACTTCGGCGCCCCCGGTGCCTACAACTGGAAAGGAAACAGCTACATGATTCAGCGCAAGGAG TGGGACTTATCTGAGTATAGTTACAAGGACCCAGAGGACCAAGGAAACCTCTATATTGGGTACACGATG CAGGTAGGCAGCTTCATCCTGCACCCCAAAAACATCACCATTGTGACAGGTGCCCCACGGCACCGACAT ATGGGCGCGGTGTTCTTGCTGAGCCAGGAGGCAGGCGGAGACCTGCGGAGGAGGCAGGTGCTGGAGGGC TCGCAGGTGGGCGCCTATTTTGGCAGCGCCATTGCCCTGGCAGACCTGAACAATGATGGGTGGCAGGAC CTCCTGGTGGGCGCCCCCTACTACTTTGAGAGGAAAGAGGAAGTAGGGGGTGCCATCTATGTCTTCATG AACCAGGCGGGAACCTCCTTCCCTGCTCACCCCTCACTCCTTCTTCATGGCCCCAGTGGCTCTGCCTTT GGTTTATCTGTGGCCAGCATTGGTGACATCAACCAGGATGGATTTCAGGATATTGCTGTGGGAGCTCCG TTTGAAGGCTTGGGCAAAGTGTACATCTATCACAGTAGCTCTAAGGGGCTCCTCAGACAGCCCCAGCAG GTAATCCATGGAGAGAAGCTGGGACTGCCTGGGTTGGCCACCTTCGGCTATTCCCTCAGTGGGCAGATG GATGTGGATGAGAACTTCTACCCAGACCTTCTAGTGGGAAGCCTGTCAGACCACATTGTGCTGCTGCGG GCCCGGCCCGTCATCAACATCGTCCACAAGACCTTGGTGCCCAGGCCAGCTGTGCTGGACCCTGCACTT TGCACGGCCACCTCTTGTGTGCAAGTGGAGCTGTGCTTTGCTTACAACCAGAGTGCCGGGAACCCCAAC TACAGGCGAAACATCACCCTGGCCTACACTCTGGAGGCTGACAGGGACCGCCGGCCGCCCCGGCTCCGC TTTGCCGGCAGTGAGTCCGCTGTCTTCCACGGCTTCTTCTCCATGCCCGAGATGCGCTGCCAGAAGCTG GAGCTGCTCCTGATGGACAACCTCCGTGACAAACTCCGCCCCATCATCATCTCCATGAACTACTCTTTA CCTTTGCGGATGCCCGATCGCCCCCGGCTGGGGCTGCGGTCCCTGGACGCCTACCCGATCCTCAACCAG GCACAGGCTCTGGAGAACCACACTGAGGTCCAGTTCCAGAAGGAGTGCGGGCCTGACAACAAGTGTGAG AGCAACTTGCAGATGCGGGCAGCCTTCGTGTCAGAGCAGCAGCAGAAGCTGAGCAGGCTCCAGTACAGC AGAGACGTCCGGAAATTGCTCCTGAGCATCAACGTGACGAACACCCGGACCTCGGAGCGCTCCGGGGAG GACGCCCACGAGGCGCTGCTCACCCTGGTGGTGCCTCCCGCCCTGCTGCTGTCCTCAGTGCGCCCCCCC GGGGCCTGCCAAGCTAATGAGACCATCTTTTGCGAGCTGGGGAACCCCTTCAAACGGAACCAGAGGATG GAGCTGCTCATCACCTTTGAGGTCATCGGGGTGACCCTGCACACAAGGGACCTTCAGGTGCAGCTGCAG CTCTCCACGTCGAGTCACCAGGACAACCTGTGGCCCATGATCCTCACTCTGCTGGTGGACTATACACTC CAGACCTCGCTTAGCATGGTAAATCACCGGCTACAAAGCTTCTTTGGGGGGACAGTGATGGGTGAGTCT GGCATGAAAACTGTGGAGGATGTAGGAAGCCCCCTCAAGTATGAATTCCAGGTGGGCCCAATGGGGGAG GGGCTGGTGGGCCTGGGGACCCTGGTCCTAGGTCTGGAGTGGCCCTACGAAGTCAGCAATGGCAAGTGG CTGCTGTATCCCACGGAGATCACCGTCCATGGCAATGGGTCCTGGCCCTGCCGACCACCTGGAGACCTT ATCAACCCTCTCAACCTCACTCTTTCTGACCCTGGGGACAGGCCATCATCCCCACAGCGCAGGCGGCGA CAGCTGGATCCAGGGGGAGGCCAGGGCCCCCCACCTGTCACTCTGGCTGCTGCCAAAAAAGCCAAGTCT GAGACTGTGCTGACCTGTGCCACAGGGCGTGCCCACTGTGTGTGGCTAGAGTGCCCCATCCCTGATGCC CCCGTTGTCACCAACGTGACTGTGAAGGCACGAGTGTGGAACAGCACCTTCATCGAGGATTACAGAGAC TTTGACCGAGTCCGGGTAAATGGCTGGGCTACCCTATTCCTCCGAACCAGCATCCCCACCATCAACATG GAGAACAAGACCACGTGGTTCTCTGTGGACATTGACTCGGAGCTGGTGGAGGAGCTGCCGGCCGAAATC GAGCTGTGGCTGGTGCTGGTGGCCGTGGGTGCAGGGCTGCTGCTGCTGGGGCTGATCATCCTCCTGCTG TGGAAGTGTGACTTCTTTAAGCGGACCCGCTATTATCAGATCATGCCCAAGTACCACGCAGTGCGGATC CGGGAGGAGGAGCGCTACCCACCTCCAGGGAGCACCCTGCCCACCAAGAAGCACTGGGTGACCAGCTGG CAGACTCGGGACCAATACTACTGACGTCCTCCCTGATCCCACCCCCTCCTCCCCCAGTGTCCCCTTTCT TCCTATTTATCATAAGTTATGCCTCTGACAGTCCACAGGGGCCACCACCTTTGGCTGGTAGCAGCAGGC TCAGGCACATACACCTCGTCAAGAGCATGCACATGCTGTCTGGCCCTGGGGATCTTCCCACAGGAGGGC CAGCGCTGTGGACCTTACAACGCCGAGTGCACTGCATTCCTGTGCCCTAGATGCACGTGGGGCCCACTG CTCGTGGACTGTGCTGGTGCATCACGGATGGTGCATGGGCTCGCCGTGTCTCAGCCTCTGCCAGCGCCA AAACAAGCCAAAGAGCCTCCCACCAGAGCTGGGAGGAAAAGGCCCCTGCAATGTGGTGACACCTCCCCC TTTCACACTGGATCCATCTTGAGCCACAGTCACTGGATTGACTTTGCTGTCAAAACTACTGACAGGGAG CAGCCCCCGGGCCGCTGGCTGGTGGGCCCCCAATGACACCCATGCCAGAGAGGTGGGGATCCTGCCTAA GGTTGTCTACGGGGGCACTTGGAGGACCTGGCGTGCTCAGACCCAACAGCAAAGGAACTAGAAAGAAGG ACCCAGAACGGCTTGCTTTCCTGCATCTCTGTGAAGCCTCTCTCCTTGGCCACAGACTGAACTCGCAGG GAGTGCAGCAGGAAGGAACAAAGACAGGCAAACGGCAACGTAGCCTGGGCTCACTGTGCTGGGGCACGG CGGGATCCTCCACAGAGAGGAGGGGACCAATTCTGGACAGACAGATGTTGGGAGGATACAGAGGAGATG CCACTTCTCACTCACCACTACCAGCCAGCCTCAGAAGGCCCCAGAGAGACCCTGCAAGACCACGGAGGG AGCGACACTTGAATGTAGAATAGGCAGGGGGCCCTGCCCCACCCCATCCAGCCAGACCCCACGCTGACC ATGCGTCAGGGGCCTAGAGGTGGAGTTCTTAGCTATCCTTGGCTTTCAGAGCCAGCCTGGCTCTGCCCC CTCCCCCATGGGCTGTGTCCTAAGGCCCATTTGAGAAGCTGAGGCTAGTTCCAGAAAACCTCTCCTGAC CCCTGCCTGTTGGCAGGCCCACTCCCCAGCCCCAGCCCCTTCCATGGTACTGTAGCAGGGGAATTCCCT CCCCCTCCTTGTGCCTTCTTTGTATATAGGCTTCTCACGGCGACCAATAAACAGCTCCCAGTTTGCAAA AAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGC |
Restriction Sites | SgfI-MluI |
ACCN | NM_005501 |
Insert Size | 4798 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_005501.1 |
RefSeq Size | 4495 bp |
RefSeq ORF | 4798 bp |
Locus ID | 3675 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer |
MW | 176.4 kDa |
Gene Summary | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015] Transcript Variant: This variant (b) is missing the penultimate exon found in transcript variant a. This results in a frame-shift and a longer isoform (b) with a distinct C-terminus compared to isoform a. |
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Product Manuals |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC220975 | ITGA3 (Myc-DDK-tagged)-Human integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) (ITGA3), transcript variant b |
CNY 7,424.00 |
|
RC220975L3 | Lenti ORF clone of Human integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) (ITGA3), transcript variant b, Myc-DDK-tagged |
CNY 13,210.00 |
|
RC220975L4 | Lenti ORF clone of Human integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) (ITGA3), transcript variant b, mGFP tagged |
CNY 13,210.00 |
|
RG220975 | ITGA3 (tGFP-tagged) - Human integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) (ITGA3), transcript variant b |
CNY 12,450.00 |
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