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Hairless (HR) (NM_005144) Human Untagged Clone
CAT＃: SC303591
HR (untagged)-Human hairless homolog (mouse) (HR), transcript variant 1
CNY 8,288.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ALUNC; AU; HSA277165; HYPT4; MUHH; MUHH1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_005144 edited
GGCCCCGGAGCTGGCCCATGGGGAGCAGGCGCCCGGTGCCGGCCACGACGACCGCCACCG CCCGCGCCGCGACCGGCCGGTGAAGCCCAGGGACCCCCCTCTCGGAGAGCCCCATGAGGG CAGGAGAGTGATGGAGAGTACGCCCAGCTTCCTGAAGGGCACCCCAACCTGGGAGAAGAC GGCCCCAGAGAACGGCATCGTGAGACAGGAGCCCGGCAGCCCGCCTCGAGATGGACTGCA CCATGGGCCGCTGTGCCTGGGAGAGCCTGCTCCCTTTTGGAGGGGCGTCCTGAGCACCCC AGACTCCTGGCTTCCCCCTGGCTTCCCCCAGGGCCCCAAGGACATGCTCCCACTTGTGGA GGGCGAGGGCCCCCAGAATGGGGAGAGGAAGGTCAACTGGCTGGGCAGCAAAGAGGGACT GCGCTGGAAGGAGGCCATGCTTACCCATCCGCTGGCATTCTGCGGGCCAGCGTGCCCACC TCGCTGTGGCCCCCTGATGCCTGAGCATAGTGGTGGCCATCTCAAGAGTGACCCTGTGGC CTTCCGGCCCTGGCACTGCCCTTTCCTTCTGGAGACCAAGATCCTGGAGCGAGCTCCCTT CTGGGTGCCCACCTGCTTGCCACCCTACCTAGTGTCTGGCCTGCCCCCAGAGCATCCATG TGACTGGCCCCTGACCCCGCACCCCTGGGTATACTCCGGGGGCCAGCCCAAAGTGCCCTC TGCCTTCAGCTTAGGCAGCAAGGGCTTTTACTACAAGGATCCGAGCATTCCCAGGTTGGC AAAGGAGCCCTTGGCAGCTGCGGAACCTGGGTTGTTTGGCTTAAACTCTGGTGGGCACCT GCAGAGAGCCGGGGAGGCCGAACGCCCTTCACTGCACCAGAGGGATGGAGAGATGGGAGC TGGCCGGCAGCAGAATCCTTGCCCGCTCTTCCTGGGGCAGCCAGACACTGTGCCCTGGAC CTCCTGGCCCGCTTGTCCCCCAGGCCTTGTTCATACTCTTGGCAACGTCTGGGCTGGGCC AGGCGATGGGAACCTTGGGTACCAGCTGGGGCCACCAGCAACACCAAGGTGCCCCTCTCC TGAGCCGCCTGTCACCCAGCGGGGCTGCTGTTCATCCTACCCACCCACTAAAGGTGGGGG TCTTGGCCCTTGTGGGAAGTGCCAGGAGGGCCTGGAGGGGGGTGCCAGTGGAGCCAGCGA ACCCAGCGAGGAAGTGAACAAGGCCTCTGGCCCCAGGGCCTGTCCCCCCAGCCACCACAC CAAGCTGAAGAAGACATGGCTCACACGGCACTCGGAGCAGTTTGAATGTCCACGCGGCTG CCCTGAGGTCGAGGAGAGGCCGGTTGCTCGGCTCCGGGCCCTCAAAAGGGCAGGCAGCCC CGAGGTCCAGGGAGCAATGGGCAGTCCAGCCCCCAAGCGGCCACCGGACCCTTTCCCAGG CACTGCAGAACAGGGGGCTGGGGGTTGGCAGGAGGTGCGGGACACATCGATAGGGAACAA GGATGTGGACTCGGGACAGCATGATGAGCAGAAAGGACCCCAAGATGGCCAGGCCAGTCT CCAGGACCCGGGACTTCAGGACATACCATGCCTGGCTCTCCCTGCAAAACTGGCTCAATG CCAAAGTTGTGCCCAGGCAGCTGGAGAGGGAGGAGGGCACGCCTGCCACTCTCAGCAAGT GCGGAGATCGCCTCTGGGAGGGGAGCTGCAGCAGGAGGAAGACACAGCCACCAACTCCAG CTCTGAGGAAGGCCCAGGGTCCGGCCCTGACAGCCGGCTCAGCACAGGCCTCGCCAAGCA CCTGCTCAGTGGTTTGGGGGACCGACTGTGCCGCCTGCTGCGGAGGGAGCGGGAGGCCCT GGCTTGGGCCCAGCGGGAAGGCCAAGGGCCAGCCGTGACAGAGGACAGCCCAGGCATTCC ACGCTGCTGCAGCCGTTGCCACCATGGACTCTTCAACACCCACTGGCGATGTCCCCGCTG CAGCCACCGGCTGTGTGTGGCCTGTGGTCGTGTGGCAGGCACTGGGCGGGCCAGGGAGAA AGCAGGCTTTCAGGAGCAGTCCGCGGAGGAGTGCACGCAGGAGGCCGGGCACGCTGCCTG TTCCCTGATGCTGACCCAGTTTGTCTCCAGCCAGGCTTTGGCAGAGCTGAGCACTGCAAT GCACCAGGTCTGGGTCAAGTTTGATATCCGGGGGCACTGCCCCTGCCAAGCTGATGCCCG GGTATGGGCCCCCGGGGATGCAGGCCAGCAGAAGGAATCAACACAGAAAACGCCCCCAAC TCCACAACCTTCCTGCAATGGCGACACCCACAGGACCAAGAGCATCAAAGAGGAGACCCC CGATTCCGCTGAGACCCCAGCAGAGGACCGTGCTGGCCGAGGGCCCCTGCCTTGTCCTTC TCTCTGCGAACTGCTGGCTTCTACCGCGGTCAAACTCTGCTTGGGCCATGAGCGAATACA CATGGCCTTCGCCCCCGTCACTCCGGCCCTGCCCAGTGATGACCGCATCACCAACATCCT GGACAGCATTATCGCACAGGTGGTGGAACGGAAGATCCAGGAGAAAGCCCTGGGGCCGGG GCTTCGAGCTGGCCCGGGTCTGCGCAAGGGCCTGGGCCTGCCCCTCTCTCCAGTGCGGCC CCGGCTGCCTCCCCCAGGGGCTTTGCTGTGGCTGCAGGAGCCCCAGCCTTGCCCTCGGCG TGGCTTCCACCTCTTCCAGGAGCACTGGAGGCAGGGCCAGCCTGTGTTGGTGTCAGGGAT CCAAAGGACATTGCAGGGCAACCTGTGGGGGACAGAAGCTCTTGGGGCACTTGGAGGCCA GGTGCAGGCGCTGAGCCCCCTCGGACCTCCCCAGCCCAGCAGCCTGGGCAGCACAACATT CTGGGAGGGCTTCTCCTGGCCTGAGCTTCGCCCAAAGTCAGACGAGGGCTCTGTCCTCCT GCTGCACCGAGCTTTGGGGGATGAGGACACCAGCAGGGTGGAGAACCTAGCTGCCAGTCT GCCACTTCCGGAGTACTGCGCCCTCCATGGAAAACTCAACCTGGCTTCCTACCTCCCACC GGGCCTTGCCCTGCGTCCACTGGAGCCCCAGCTCTGGGCAGCCTATGGTGTGAGCCCGCA CCGGGGACACCTGGGGACCAAGAACCTCTGTGTGGAGGTGGCCGACCTGGTCAGCATCCT GGTGCATGCCGACACACCACTGCCTGCCTGGCACCGGGCACAGAAAGACTTCCTTTCAGG CCTGGACGGGGAGGGGCTCTGGTCTCCGGGCAGCCAGGTCAGCACTGTGTGGCACGTGTT CCGGGCACAGGACGCCCAGCGCATCCGCCGCTTTCTCCAGATGGTGTGCCCGGCCGGGGC AGGCGCCCTGGAGCCTGGCGCCCCAGGCAGCTGCTACCTGGATGCAGGGCTGCGGCGGCG CCTGCGGGAGGAGTGGGGCGTGAGCTGCTGGACCCTGCTCCAGGCCCCCGGAGAGGCCGT GCTGGTGCCTGCAGGGGCTCCCCACCAGGTGCAGGGCCTGGTGAGCACAGTCAGCGTCAC TCAGCACTTCCTCTCCCCTGAGACCTCTGCCCTCTCTGCTCAGCTCTGCCACCAGGGACC CAGCCTTCCCCCTGACTGCCACCTGCTTTATGCCCAGATGGACTGGGCTGTGTTCCAAGC AGTGAAGGTGGCCGTGGGGACATTACAGGAGGCCAAATAGAGGGATGCTAGGTGTCTGGG ATCGGGGTGGGGACAGGTAGACCAGGTGCTCAGCCCAGGCACAACTTCAGCAGGGGATGG CGCTAGGGGACTTGGGGATTTCTGGTCAACCCCACAAGCACCACTCTGGGCACAAGCAGG GCACTCTGTTCCCCTCCCCCTTAAGCCAACAACCACAGTGCCACCAAGCTCACACCTGTC CTTCTCAGGCTGGCATCTCCCCCACCCTGTGCCCCTTTTCATGGTACCAGGCCCGCACTG GGGGCAATTGACTTCCTCCAATCCCCACTCCTCCGAGACCCAGGAGACAAACAGCCCTTC CTTGGGGAAACTTGGGAATCATTCTGGCTTAAACAACACCTCCTCCTGCTGCTCACTCCC GCTGAGCCCACTCTACTGCCCCAGCTCCGTTTCTACCACCGCATCCTCACTGGGCTCACT GCAGGCATGCTGAACAAGGGGCCTCCAACCTTCTGCCCTCCTGCCAAAAGATCTGGGGAG TGTGAGGAGAGGGTGGCATCAGGAGCTGCTCAGGCTTGGCGGAGGGAGCGGCATGGGCGA TGTCACTCAGCCCCTTCCCGGTCCGCCCGCTTCCCTCCTTCATGATTTCCATTAAAGTCT GTTGTTTTGTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_005144 unedited
TCCGGAATCTAGCCTAAGCCGCGGGACGGATAACAAATTCACACAGGAAACGCCATGACC ATTAAGCCTCTTTAGGTGACACTATAGAACAAGTTTTGTACAAAAAAACAGGCTGGTACC GGTCCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGGGCCCCGGAGCTGGCCCATGG GGAGCAGGCGCCCGGTGCCGGCCACGACGACCGCCACCGCCCGCGCCGCGACCGGCCGGT GAAGCCCAGGGACCCCCCTCTCGGAGAGCCCCATGAGGGCAGGAGAGTGATGGAGAGTAC GCCCAGCTTCCTGAAGGGCACCCCAACCTGGGAGAAGACGGCCCCAGAGAACGGCATCGT GAGACAGGAGCCCGGCAGCCCGCCTCGAGATGGACTGCACCATGGGCCGCTGTGCCTGGG AGAGCCTGCTCCCTTTTGGAGGGGCGTCCTGAGCACCCCAGACTCCTGGCTTCCCCCTGG CTTCCCCCAGGGCCCCAAGGACATGCTCCCACTTGTGGAGGGCGAGGGCCCCCAGAATGG GGAGAGGAAAGTCAACTGGCTGGGCAGCAAAGAGGGACTGCGCTGGAAGGAGGCCATGCT TACCCATCCGCTGGCATTCTGCGGGCCAGCGTGCCCACCTCGCTGTGGCCCCCTGATGCC TGAGCATAGTGGTGGCCATCTCAAGATGACCCTGTGGCCTTCCGGCCCTGGCACTGCCCT TTCCTTCTGGAGACCAAGATCCTGGGACGAGCTTCCTTCTGGGTGCCCACCTGCTTGCCA CCCTACCTAATGTACTGGCCTGCCCCCAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005144 |
| Insert Size | 4400 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005144.3, NP_005135.2 |
| RefSeq Size | 4981 bp |
| RefSeq ORF | 3570 bp |
| Locus ID | 55806 |
| UniProt ID | O43593 |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record represents the hairless protein encoded by the primary ORF. Four upstream ORFs (U1HR-U4HR), which may regulate translation of the primary ORF as described in PMID:19122663, are also annotated on this sequence. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209010 | HR (Myc-DDK-tagged)-Human hairless homolog (mouse) (HR), transcript variant 1 |
CNY 8,280.00 |
|
| RC209010L3 | Lenti ORF clone of Human hairless homolog (mouse) (HR), transcript variant 1, Myc-DDK-tagged |
CNY 11,500.00 |
|
| RC209010L4 | Lenti ORF clone of Human hairless homolog (mouse) (HR), transcript variant 1, mGFP tagged |
CNY 11,500.00 |
|
| RG209010 | HR (tGFP-tagged) - Human hairless homolog (mouse) (HR), transcript variant 1 |
CNY 10,550.00 |
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