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Klotho (KL) (NM_004795) Human Untagged Clone
CNY 10,576.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HFTC3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_004795 edited
GAATTCGCATGCCCGCCAGCGCCCCGCCGCGCCGCCCGCGGCCGCCGCCGCCGTCGCTGT CGCTGCTGCTGGTGCTGCTGGGCCTGGGCGGCCGCCGCCTGCGTGCGGAGCCGGGCGACG GCGCGCAGACCTGGGCCCGTTTCTCGCGGCCTCCTGCCCCCGAGGCCGCGGGCCTCTTCC AGGGCACCTTCCCCGACGGCTTCCTCTGGGCCGTGGGCAGCGCCGCCTACCAGACCGAGG GCGGCTGGCAGCAGCACGGCAAGGGTGCGTCCATCTGGGATACGTTCACCCACCACCCCC TGGCACCCCCGGGAGACTCCCGGAACGCCAGTCTGCCGTTGGGCGCCCCGTCGCCGCTGC AGCCCGCCACCGGGGACGTAGCCAGCGACAGCTACAACAACGTCTTCCGCGACACGGAGG CGCTGCGCGAGCTCGGGGTCACTCACTACCGCTTCTCCATCTCGTGGGCGCGAGTGCTCC CCAATGGCAGCGCGGGCGTCCCCAACCGCGAGGGGCTGCGCTACTACCGGCGCCTGCTGG AGCGGCTGCGGGAGCTGGGCGTGCAGCCCGTGGTCACCCTGTACCACTGGGACCTGCCCC AGCGCCTGCAGGACGCCTACGGCGGCTGGGCCAACCGCGCCCTGGCCGACCACTTCAGGG ATTACGCGGAGCTCTGCTTCCGCCACTTCGGCGGTCAGGTCAAGTACTGGATCACCATCG ACAACCCCTACGTGGTGGCCTGGCACGGCTACGCCACCGGGCGCCTGGCCCCCGGCATCC GGGGCAGCCCGCGGCTCGGGTACCTGGTGGCGCACAACCTCCTCCTGGCTCATGCCAAAG TCTGGCATCTCTACAATACTTCTTTCCGTCCCACTCAGGGAGGTCAGGTGTCCATTGCCC TAAGCTCTCACTGGATCAATCCTCGAAGAATGACCGACCACAGCATCAAAGAATGTCAAA AATCTCTGGACTTTGTACTAGGTTGGTTTGCCAAACCCGTATTTATTGATGGTGACTATC CCGAGAGCATGAAGAATAACCTTTCATCTATTCTGCCTGATTTTACTGAATCTGAGAAAA AGTTCATCAAAGGAACTGCTGACTTTTTTGCTCTTTGCTTTGGACCCACCTTGAGTTTTC AACTTTTGGACCCTCACATGAAGTTCCGCCAATTGGAATCTCCCAACCTGAGGCAACTGC TTTCCTGGATTGACCTTGAATTTAACCATCCTCAAATATTTATTGTGGAAAATGGCTGGT TTGTCTCAGGGACCACCAAGAGAGATGATGCCAAATATATGTATTACCTCAAAAAGTTCA TCATGGAAACCTTAAAAGCCATCAAGCTGGATGGGGTGGATGTCATCGGGTATACCGCAT GGTCCCTCATGGATGGTTTCGAGTGGCACAGAGGTTACAGCATCAGGCGTGGACTCTTCT ATGTTGACTTTCTAAGCCAGGACAAGATGTTGTTGCCAAAGTCTTCAGCCTTGTTCTACC AAAAGCTGATAGAGAAAAATGGCTTCCCTCCTTTACCTGAAAATCAGCCCCTAGAAGGGA CATTTCCCTGTGACTTTGCTTGGGGAGTTGTTGACAACTACATTCAAGTAGATACCACTC TGTCTCAGTTTACCGACCTGAATGTTTACCTGTGGGATGTCCACCACAGTAAAAGGCTTA TTAAAGTGGATGGGGTTGTGACCAAGAAGAGGAAATCCTACTGTGTTGACTTTGCTGCCA TCCAGCCCCAGATCGCTTTACTCCAGGAAATGCACGTTACACATTTTCGCTTCTCCCTGG ACTGGGCCCTGATTCTCCCTCTGGGTAACCAGTCCCAGGTGAACCACACCATCCTGCAGT ACTATCGCTGCATGGCCAGCGAGCTTGTCCGTGTCAACATCACCCCAGTGGTGGCCCTGT GGCAGCCTATGGCCCCGAACCAAGGACTGCCGCGCCTCCTGGCCAGGCAGGGCGCCTGGG AGAACCCCTACACTGCCCTGGCCTTTGCAGAGTATGCCCGACTGTGCTTTCAAGAGCTCG GCCATCACGTCAAGCTTTGGATAACGATGAATGAGCCGTATACAAGGAATATGACATACA GTGCTGGCCACAACCTTCTGAAGGCCCATGCCCTGGCTTGGCATGTGTACAATGAAAAGT TTAGGCATGCTCAGAATGGGAAAATATCCATAGCCTTGCAGGCTGATTGGATAGAACCTG CCTGCCCTTTCTCCCAAAAGGACAAAGAGGTGGCCGAGAGAGTTTTGGAATTTGACATTG GCTGGCTGGCTGAGCCCATTTTCGGCTCTGGAGATTATCCATGGGTGATGAGGGACTGGC TGAACCAAAGAAACAATTTTCTTCTTCCTTATTTCACTGAAGATGAAAAAAAGCTAATCC AGGGTACCTTTGACTTTTTGGCTTTAAGCCATTATACCACCATCCTTGTAGACTCAGAAA AAGAAGATCCAATAAAATACAATGATTACCTAGAAGTGCAAGAAATGACCGACATCACGT GGCTCAACTCCCCCAGTCAGGTGGCGGTAGTGCCCTGGGGGTTGCGCAAAGTGCTGAACT GGCTGAAGTTCAAGTACGGAGACCTCCCCATGTACATAATATCCAACGGAATCGATGACG GGCTGCATGCTGAGGACGACCAGCTGAGGGTGTATTATATGCAGAATTACATAAACGAAG CTCTCAAAGCCCACATACTGGATGGTATCAATCTTTGCGGATACTTTGCTTATTCGTTTA ACGACCGCACAGCTCCGAGGTTTGGCCTCTATCGTTATGCTGCAGATCAGTTTGAGCCCA AGGCATCCATGAAACATTACAGGAAAATTATTGACAGCAATGGTTTCCCGGGCCCAGAAA CTCTGGAAAGATTTTGTCCAGAAGAATTCACCGTGTGTACTGAGTGCAGTTTTTTTCACA CCCGAAAGTCTTTACTGGCTTTCATAGCTTTTCTATTTTTTGCTTCTATTATTTCTCTCT CCCTTATATTTTACTACTCGAAGAAAGGCAGAAGAAGTTACAAATAGTTCTGAACATTTT TCTATTCATTCATTTTGAAATAATTATGCAGACACATCAGCTGTTAACCATTTGCACCTC TAAGTGTTGTGAAACTGTAAATTTCAT |
| Restriction Sites | Please inquire |
| ACCN | NM_004795 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004795.2, NP_004786.2 |
| RefSeq Size | 5003 bp |
| RefSeq ORF | 3039 bp |
| Locus ID | 9365 |
| UniProt ID | Q9UEF7 |
| Protein Families | Secreted Protein, Transmembrane |
| Gene Summary | This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents a shorter transcript, but encodes a longer, membrane bound isoform (a). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224132 | KL (Myc-DDK-tagged)-Human klotho (KL) |
CNY 10,568.00 |
|
| RC224132L1 | Lenti ORF clone of Human klotho (KL), Myc-DDK-tagged |
CNY 12,968.00 |
|
| RC224132L2 | Lenti ORF clone of Human klotho (KL), mGFP tagged |
CNY 12,968.00 |
|
| RC224132L3 | Lenti ORF clone of Human klotho (KL), Myc-DDK-tagged |
CNY 12,968.00 |
|
| RC224132L4 | Lenti ORF clone of Human klotho (KL), mGFP tagged |
CNY 12,968.00 |
|
| RG224132 | KL (tGFP-tagged) - Human klotho (KL) |
CNY 12,168.00 |
