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NOTCH4 (NM_004557) Human Untagged Clone
CAT＃: SC303498
NOTCH4 (untagged)-Human notch 4 (NOTCH4)
CNY 13,232.00
货期*
现货
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | INT3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_004557 edited
CAGGCCGAGGAGGAAGAAGAGGGGCAGTGGGAGCAGAGGAGGTGGCTCCTGCCCCAGTGA GAGCTCTGAGGGTCCCTGCCTGAAGAGGGACAGGGACTGGGGCTTGGAGAAGGGGCTGTG GAATGCAGCCCCCTTCACTGCTGCTGCTGCTGCTGCTGCTGCTGCTATGTGTCTCAGTGG TCAGACCCAGAGGGCTGCTGTGTGGGAGTTTCCCAGAACCCTGTGCCAATGGAGGCACCT GCCTGAGCCTGTCTCTGGGACAAGGGACCTGCCAGTGTGCCCCTGGCTTCCTGGGTGAGA CGTGCCAGTTTCCTGACCCCTGCCAGAACGCCCAGCTCTGCCAAAATGGAGGCAGCTGCC AAGCCCTGCTTCCCGCTCCCCTAGGGCTCCCCAGCTCTCCCTCTCCATTGACACCCAGCT TCTTGTGCACTTGCCTCCCTGGCTTCACTGGCGAGAGATGCCAGGCCCAGCTTGAAGACC CTTGTCCTCCCTCCTTCTGTTCCAAAAGGGGCCGCTGCCACATCCAGGCCTCGGGCCGCC CACAGTGCTCCTGCATGCCTGGATGGACAGGTGAGCAGTGCCAGCTTCGGGACTTCTGTT CAGCCAACCCATGTGTTAATGGAGGGGTGTGTCTGGCCACATACCCCCAGATCCAGTGCC ACTGCCCACCGGGCTTCGAGGGCCATGCCTGTGAACGTGATGTCAACGAGTGCTTCCAGG ACCCAGGACCCTGCCCCAAAGGCACCTCCTGCCATAACACCCTGGGCTCCTTCCAGTGCC TCTGCCCTGTGGGGCAGGAGGGTCCACGTTGTGAGCTGCGGGCAGGACCCTGCCCTCCTA GGGGCTGTTCGAATGGGGGCACCTGCCAGCTGATGCCAGAGAAAGACTCCACCTTTCACC TCTGCCTCTGTCCCCCAGGTTTCATAGGCCCAGACTGTGAGGTGAATCCAGACAACTGTG TCAGCCACCAGTGTCAGAATGGGGGCACTTGCCAGGATGGGCTGGACACCTACACCTGCC TCTGCCCAGAAACCTGGACAGGCTGGGACTGCTCCGAAGATGTGGATGAGTGTGAGACCC AGGGTCCCCCTCACTGCAGAAACGGGGGCACCTGCCAGAACTCTGCTGGTAGCTTTCACT GCGTGTGTGTGAGTGGCTGGGGCGGCACAAGCTGTGAGGAGAACCTGGATGACTGTATTG CTGCCACCTGTGCCCCGGGATCCACCTGCATTGACCGGGTGGGCTCTTTCTCCTGCCTCT GCCCACCTGGACGCACAGGACTCCTGTGCCACTTGGAAGACATGTGTCTGAGCCAGCCGT GCCATGGGGATGCCCAATGCAGCACCAACCCCCTCACAGGCTCCACACTCTGCCTGTGTC AGCCTGGCTATTCGGGGCCCACCTGCCACCAGGACCTGGACGAGTGTCTGATGGCCCAGC AAGGCCCAAGTCCCTGTGAACATGGCGGTTCCTGCCTCAACACTCCTGGCTCCTTCAACT GCCTCTGTCCACCTGGCTACACAGGCTCCCGTTGTGAGGCTGATCACAATGAGTGCCTCT CCCAGCCCTGCCACCCAGGAAGCACCTGTCTGGACCTACTTGCCACCTTCCACTGCCTCT GCCCGCCAGGCTTAGAAGGGCAGCTCTGTGAGGTGGAGACCAACGAGTGTGCCTCAGCTC CCTGCCTGAACCACGCGGATTGCCATGACCTGCTCAACGGCTTCCAGTGTATCTGCCTGC CTGGATTCTCCGGCACCCGATGTGAGGAGGATATCGATGAGTGCAGAAGCTCTCCCTGTG CCAATGGTGGGCAGTGCCAGGACCAGCCTGGAGCCTTCCACTGCAAGTGTCTCCCAGGCT TTGAAGGGCCACGCTGTCAAACAGAGGTGGATGAGTGCCTGAGTGACCCATGTCCCGTTG GAGCCAGCTGCCTTGATCTTCCAGGAGCCTTCTTTTGCCTCTGCCCCTCTGGTTTCACAG GCCAGCTCTGTGAGGTTCCCCTGTGTGCTCCCAACCTGTGCCAGCCCAAGCAGATATGTA AGGACCAGAAAGACAAGGCCAACTGCCTCTGTCCTGATGGAAGCCCTGGCTGTGCCCCAC CTGAGGACAACTGCACCTGCCACCACGGGCACTGCCAGAGATCCTCATGTGTGTGTGACG TGGGTTGGACGGGGCCAGAGTGTGAGGCAGAGCTAGGGGGCTGCATCTCTGCACCCTGTG CCCATGGGGGGACCTGCTACCCCCAGCCCTCTGGCTACAACTGCACCTGCCCTACAGGCT ACACAGGACCCACCTGTAGTGAGGAGATGACAGCTTGTCACTCAGGGCCATGTCTCAATG GCGGCTCCTGCAACCCTAGCCCTGGAGGCTACTACTGCACCTGCCCTCCAAGCCACACAG GGCCCCAGTGCCAAACCAGCACTGACTACTGTGTGTCTGCCCCGTGCTTCAATGGGGGTA CCTGTGTGAACAGGCCTGGCACCTTCTCCTGCCTCTGTGCCATGGGCTTCCAGGGCCCGC GCTGTGAGGGAAAGCTCCGCCCCAGCTGTGCAGACAGCCCCTGTAGGAATAGGGCAACCT GCCAGGACAGCCCTCAGGGTCCCCGCTGCCTCTGCCCCACTGGCTACACCGGAGGCAGCT GCCAGACTCTGATGGACTTATGTGCCCAGAAGCCCTGCCCACGCAATTCCCACTGCCTCC AGACTGGGCCCTCCTTCCACTGCTTGTGCCTCCAGGGATGGACCGGGCCTCTCTGCAACC TTCCACTGTCCTCCTGCCAGAAGGCTGCACTGAGCCAAGGCATAGACGTCTCTTCCCTTT GCCACAATGGAGGCCTCTGTGTCGACAGCGGCCCCTCCTATTTCTGCCACTGCCCCCCTG GATTCCAAGGCAGCCTGTGCCAGGATCACGTGAACCCATGTGAGTCCAGGCCTTGCCAGA ACGGGGCCACCTGCATGGCCCAGCCCAGTGGGTATCTCTGCCAGTGTGCCCCAGGCTACG ATGGACAGAACTGCTCAAAGGAACTCGATGCTTGTCAGTCCCAACCCTGTCACAACCATG GAACCTGTACTCCCAAACCTGGAGGCTTCCACTGTGCCTGCCCTCCAGGCTTTGTGGGGC TACGCTGTGAGGGAGACGTGGACGAGTGTCTGGACCAGCCCTGCCACCCCACAGGCACTG CAGCCTGCCACTCTCTGGCCAATGCCTTCTACTGCCAGTGTCTGCCTGGACACACAGGCC AGTGGTGTGAGGTGGAGATAGACCCCTGCCACAGCCAACCCTGCTTTCATGGAGGGACCT GTGAGGCCACAGCAGGATCACCCCTGGGTTTCATCTGCCACTGCCCCAAGGGTTTTGAAG GCCCCACCTGCAGCCACAGGGCCCCTTCCTGCGGCTTCCATCACTGCCACCACGGAGGCC TGTGTCTGCCCTCCCCTAAGCCAGGCTTCCCACCACGCTGTGCCTGCCTCAGTGGCTATG GGGGTCCTGACTGCCTGACCCCACCAGCTCCTAAAGGCTGTGGCCCTCCCTCCCCATGCC TATACAATGGCAGCTGCTCAGAGACCACGGGCTTGGGGGGCCCAGGCTTTCGATGCTCCT GCCCTCACAGCTCTCCAGGGCCCCGGTGTCAGAAACCCGGAGCCAAGGGGTGTGAGGGCA GAAGTGGAGATGGGGCCTGCGATGCTGGCTGCAGTGGCCCGGGAGGAAACTGGGATGGAG GGGACTGCTCTCTGGGAGTCCCAGACCCCTGGAAGGGCTGCCCCTCCCACTCTCGGTGCT GGCTTCTCTTCCGGGACGGGCAGTGCCACCCACAGTGTGACTCTGAAGAGTGTCTGTTTG ATGGCTACGACTGTGAGACCCCTCCAGCCTGCACTCCAGCCTATGACCAGTACTGCCATG ATCACTTCCACAACGGGCACTGTGAGAAAGGCTGCAACACTGCAGAGTGTGGCTGGGATG GAGGTGACTGCAGGCCTGAAGATGGGGACCCAGAGTGGGGGCCCTCCCTGGCCCTGCTGG TGGTACTGAGCCCCCCAGCCCTAGACCAGCAGCTGTTTGCCCTGGCCCGGGTGCTGTCCC TGACTCTGAGGGTAGGACTCTGGGTAAGGAAGGATCGTGATGGCAGGGACATGGTGTACC CCTATCCTGGGGCCCGGGCTGAAGAAAAGCTAGGAGGAACTCGGGACCCCACCTATCAGG AGAGAGCAGCCCCTCAAACGCAGCCCCTGGGCAAGGAGACCGACTCCCTCAGTGCTGGGT TTGTGGTGGTCATGGGTGTGGATTTGTCCCGCTGTGGCCCTGACCACCCGGCATCCCGCT GTCCCTGGGACCCTGGGCTTCTACTCCGCTTCCTTGCTGCGATGGCTGCAGTGGGAGCCC TGGAGCCCCTGCTGCCTGGACCACTGCTGGCTGTCCACCCTCATGCAGGGACCGCACCCC CTGCCAACCAGCTTCCCTGGCCTGTGCTGTGCTCCCCAGTGGCCGGGGTGATTCTCCTGG CCCTAGGGGCTCTTCTCGTCCTCCAGCTCATCCGGCGTCGACGCCGAGAGCATGGAGCTC TCTGGCTGCCCCCTGGTTTCACTCGACGGCCTCGGACTCAGTCAGCTCCCCACCGACGCC GGCCCCCACTAGGCGAGGACAGCATTGGTCTCAAGGCACTGAAGCCAAAGGCAGAAGTTG ATGAGGATGGAGTTGTGATGTGCTCAGGCCCTGAGGAGGGAGAGGAGGCTGAAGAAACAG GCCCACCCTCCACGTGCCAGCTCTGGTCTCTGAGTGGTGGCTGTGGGGCGCTCCCTCAGG CAGCCATGCTAACTCCTCCCCAGGAATCTGAGATGGAAGCCCCTGACCTGGACACCCGTG GACCTGATGGGGTGACACCCCTGATGTCAGCAGTTTGCTGTGGGGAAGTACAGTCCGGGA CCTTCCAAGGGGCATGGTTGGGATGTCCTGAGCCCTGGGAACCTCTGCTGGATGGAGGGG CCTGTCCCCAGGCTCACACCGTGGGCACTGGGGAGACCCCCCTGCACCTGGCTGCCCGAT TCTCCCGGCCAACCGCTGCCCGCCGCCTCCTTGAGGCTGGAGCCAACCCCAACCAGCCAG ACCGGGCAGGGCGCACACCCCTTCATGCTGCTGTGGCTGCTGATGCTCGGGAGGTCTGCC AGCTTCTGCTCCGTAGCAGACAAACTGCAGTGGACGCTCGCACAGAGGACGGGACCACAC CCTTGATGCTGGCTGCCAGGCTGGCGGTGGAAGACCTGGTTGAAGAACTGATTGCAGCCC AAGCAGACGTGGGGGCCAGAGATAAATGGGGGAAAACTGCGCTGCACTGGGCTGCTGCCG TGAACAACGCCCGAGCCGCCCGCTCGCTTCTCCAGGCCGGAGCCGATAAAGATGCCCAGG ACAACAGGGAGCAGACGCCGCTATTCCTGGCGGCGCGGGAAGGAGCGGTGGAAGTAGCCC AGCTACTGCTGGGGCTGGGGGCAGCCCGAGAGCTGCGGGACCAGGCTGGGCTAGCGCCGG CGGACGTCGCTCACCAACGTAACCACTGGGATCTGCTGACGCTGCTGGAAGGGGCTGGGC CACCAGAGGCCCGTCACAAAGCCACGCCGGGCCGCGAGGCTGGGCCCTTCCCGCGCGCAC GGACGGTGTCAGTAAGCGTGCCCCCGCATGGGGGCGGGGCTCTGCCGCGCTGCCGGACGC TGTCAGCCGGAGCAGGCCCTCGTGGGGGCGGAGCTTGTCTGCAGGCTCGGACTTGGTCCG TAGACTTGGCTGCGCGGGGGGGCGGGGCCTATTCTCATTGCCGGAGCCTCTCGGGAGTAG GAGCAGGAGGAGGCCCGACCCCTCGCGGCCGTAGGTTTTCTGCAGGCATGCGCGGGCCTC GGCCCAACCCTGCGATAATGCGAGGAAGATACGGAGTGGCTGCCGGGCGCGGAGGCAGGG TCTCAACGGATGACTGGCCCTGTGATTGGGTGGCCCTGGGAGCTTGCGGTTCTGCCTCCA ACATTCCGATCCCGCCTCCTTGCCTTACTCCGTCCCCGGAGCGGGGATCACCTCAACTTG ACTGTGGTCCCCCAGCCCTCCAAGAAATGCCCATAAACCAAGGAGGAGAGGGTAAAAAAT AGAAGAATACATGGTAGGGAGGAATTCCAAAAATGATTACCCATTAAAAGGCAGGCTGGA AGGCCTTCCTGGTTTTAAGATGGATCCCCCAAAATGAAGGGTTGTGAGTTTAGTTTCTCT CCTAAAATGAATGTATGCCCACCAGAGCAGACATCTTCCACGTGGAGAAGCTGCAGCTCT GGAAAGAGGGTTTAAGATGCTAGGATGAGGCAGGCCCAGTCCTCCTCCAGAAAATAAGAC AGGCCACAGGAGGGCAGAGTGGAGTGGAAATACCCCTAAGTTGGAACCAAGAATTGCAGG CATATGGGATGTAAGATGTTCTTTCCTATATATGGTTTCCAAAGGGTGCCCCTATGATCC ATTGTCCCCACTGCCCACAAATGGCTGACAAATATTTATTGGGCACCTACTATGTGCCAG GCACTGTGTAGGTGCTGAAAAGTGGCCAAGGGCCACCCCCGCTGATGACTCCTTGCATTC CCTCCCCTCACAACAAAGAACTCCACTGTGGGGATGAAGCGCTTCTTCTAGCCACTGCTA TCGCTATTTAAGAACCCTAAATCTGTCACCCATAATAAAGCTGATTTGAAGTGTTAAAAA AAAAAAAAAAAAA >OriGene 5' read for NM_004557 unedited
TTTTGTCCCGTTCACATTTGTAATACCACNCACTATAGGGCGGCCGCGGAATTCGCACCA GGCAGGCCGAGGAGGAAGAAGAGGGCAGTGGGAGCAGAGGAGGTGGCTCCTGCCCCAGTG AGAGCTCTGAGGGTCCCTGCCTGAAGAGGGACAGGGACTGGGGCTTGGAGAAGGGGCTGT GGAATGCAGCCCCCTTCACTGCTGCTGCTGCTGCTGCTGCTGCTGCTATGTGTCTCAGTG GTCAGACCCAGAGGGCTGCTGTGTGGGAGTTTCCCAGAACCCTGTGCCAATGGAGGCACC TGCCTGAGCCTGTCTCTGGGACAAGGGACCTGCCAGTGTGCCCCTGGCTTCCTGGGTGAG ACGTGCCAGTTTCCTGACCCCTGCCAGAACGCCCAGCTCTGCCAAAATGGAGGCAGCTGC CAAGCCCTGCTTCCCGCTCCCCTAGGGCTCCCCAGCTCTCCCTCTCCATTGACACCCAGC TTCTTGTGCACTTGCCTCCCTGGCTTCACTGGCGAGAGATGCCAGGCCCAGCTTGAAGAC CCTTGTCCTCCCTCCTTCTGTTCCAAAAGGGGCCGCTGCCACATCCAGGCCTCGGGCCGC CCACAGTGCTCCTGCATGCCTGGATGGACAGGTGAGCAGTGCCAGCTTCGGGACTTCTGT TCAGCCAACCCATGTGTTAATGGAGGGGTGTGTCTGGCCACATACCCCCAGATCCAGTGC CACTGCCCACCCGGCTTCCAGGGCCATGCCTGTGAACGTGATGTCAACGAGTGCTTCCAG GACCCATGACCCTGCCCCCATGGCACCTCCTGCCATAACACCCTGGGCTCCTTCCAGTGC CTCTGCCCTGTGGGGCAAGACGGTCCAC >OriGene 3' read for NM_004557 unedited
TTNCCCGGCCTTGGTGATGGCACTTCCCAGGNCCAGNGNGAGCACTGGGGNAGGGTCACA GGNTGCCACCCGGGNATCTGTTCAGNAAACAGCTATGACCGCGGCCGCAATCTAGAGTCG AGTTTTTTTTTTTTTTTTTTAACACTTCAAATCAGCTTTATTATGGGTGACAGATTTAGG GTTCTTAAATAGCGATAGCAGTGGCTAGAAGAAGCGCTTCATCCCCACAGTGGAGTTCTT TGTTGTGAGGGGAGGGAATGCAAGGAGTCATCAGCGGGGGTGGCCCTTGGCCACTTTTCA GCACCTACACAGTGCCTGGCACATAGTAGGTGCCCAATAAATATTTGTCAGCCATTTGTG GGCAGTGGGGACAATGGATCATAGGGGCACCCTTTGGAAACCATATATAGGAAAGAACAT CTTACATCCCATATGCCTGCAATTCTTGGTTCCAACTTAGGGGTATTTCCACTCCACTCT GCCCTCCTGTGGCCTGTCTTATTTTCTGGAGGAGGACTGGGCCTGCCTCATCCTAGCATC TTAAACCCTCTTTCCAGAGCTGCAGCTTCTCCACGTGGAAGATGTCTGCTCTGGTGGGCA TACATTCATTTTAGGAGAGAAACTAAACTCACAACCCTTCATTTTGGGGGATCCATCTTA AAACCAGGAAGGCCTTCCAGCCTGCCTTTTAATGGGTAATCATTTTTGGAATTCCTCCCT ACCATGTATTCTTCTATTTTTTACCCTCTCCTCCTTGGTTTATGGGCATTTCTTGGGAGG CTGGGGGACCACAGTCAAGTTGAGGTGATCCCCGCTCCGGGGACGGAGTAAGGCAAGGNA GCGGGATCCGGATGTNTGNAGCAGAACCCGCAGCTCCCAGGA |
| Restriction Sites | Please inquire |
| ACCN | NM_004557 |
| Insert Size | 6700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | There are 17 nucleotide differences between the OriGene clone and the NCBI reference ORF. OriGene considers these to be polymorphisms and to reflect the natural differences between individuals. These result in the substitution of 5 amino acid ( 4 deletion and 1sub). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004557.3, NP_004548.3 |
| RefSeq Size | 6762 bp |
| RefSeq ORF | 6012 bp |
| Locus ID | 4855 |
| UniProt ID | Q99466 |
| Protein Families | Druggable Genome |
| Protein Pathways | Dorso-ventral axis formation, Notch signaling pathway |
| Gene Summary | This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] Transcript Variant: This variant (1) represents the longest transcript and encodes the protein. |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221762 | NOTCH4 (Myc-DDK-tagged)-Human notch 4 (NOTCH4) |
CNY 19,832.00 |
|
| RC221762L1 | Lenti ORF clone of Human notch 4 (NOTCH4), Myc-DDK-tagged |
CNY 22,232.00 |
|
| RG221762 | NOTCH4 (tGFP-tagged) - Human notch 4 (NOTCH4) |
CNY 21,432.00 |
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