United States
Germany
Japan
United Kingdom
China
NAIP (NM_004536) Human Untagged Clone
CAT＃: SC303496
NAIP (untagged)-Human NLR family, apoptosis inhibitory protein (NAIP), transcript variant 1
CNY 14,408.00
货期*
现货
规格
| Cited in 4 publications. |
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BIRC1; NLRB1; psiNAIP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_004536 edited
AAAGGACGGACAGAGCATTTGTTCTTCAGCCACATACTTTCCTTCCACTGGCCAGCATTC TCCTCTATTAGACTAGAACTGTGGATAAACCTCAGAAAATGGCCACCCAGCAGAAAGCCT CTGACGAGAGGATCTCCCAGTTTGATCACAATTTGCTGCCAGAGCTGTCTGCTCTTCTGG GCCTAGATGCAGTTCAGTTGGCAAAGGAACTAGAAGAAGAGGAGCAGAAGGAGCGAGCAA AAATGCAGAAAGGCTACAACTCTCAAATGCGCAGTGAAGCAAAAAGGTTAAAGACTTTTG TGACTTATGAGCCGTACAGCTCATGGATACCACAGGAGATGGCGGCCGCTGGGTTTTACT TCACTGGGGTAAAATCTGGGATTCAGTGCTTCTGCTGTAGCCTAATCCTCTTTGGTGCCG GCCTCACGAGACTCCCCATAGAAGACCACAAGAGGTTTCATCCAGATTGTGGGTTCCTTT TGAACAAGGATGTTGGTAACATTGCCAAGTACGACATAAGGGTGAAGAATCTGAAGAGCA GGCTGAGAGGAGGTAAAATGAGGTACCAAGAAGAGGAGGCTAGACTTGCATCCTTCAGGA ACTGGCCATTTTATGTCCAAGGGATATCCCCTTGTGTGCTCTCAGAGGCTGGCTTTGTCT TTACAGGTAAACAGGACACGGTACAGTGTTTTTCCTGTGGTGGATGTTTAGGAAATTGGG AAGAAGGAGATGATCCTTGGAAGGAACATGCCAAATGGTTCCCCAAATGTGAATTTCTTC GGAGTAAGAAATCCTCAGAGGAAATTACCCAGTATATTCAAAGCTACAAGGGATTTGTTG ACATAACGGGAGAACATTTTGTGAATTCCTGGGTCCAGAGAGAATTACCTATGGCATCAG CTTATTGCAATGACAGCATCTTTGCTTACGAAGAACTACGGCTGGACTCTTTTAAGGACT GGCCCCGGGAATCAGCTGTGGGAGTTGCAGCACTGGCCAAAGCAGGTCTTTTCTACACAG GTATAAAGGACATCGTCCAGTGCTTTTCCTGTGGAGGGTGTTTAGAGAAATGGCAGGAAG GTGATGACCCATTAGACGATCACACCAGATGTTTTCCCAATTGTCCATTTCTCCAAAATA TGAAGTCCTCTGCGGAAGTGACTCCAGACCTTCAGAGCCGTGGTGAACTTTGTGAATTAC TGGAAACCACAAGTGAAAGCAATCTTGAAGATTCAATAGCAGTTGGTCCTATAGTGCCAG AAATGGCACAGGGTGAAGCCCAGTGGTTTCAAGAGGCAAAGAATCTGAATGAGCAGCTGA GAGCAGCTTATACCAGCGCCAGTTTCCGCCACATGTCTTTGCTTGATATCTCTTCCGATC TGGCCACGGACCACTTGCTGGGCTGTGATCTGTCTATTGCTTCAAAACACATCAGCAAAC CTGTGCAAGAACCTCTGGTGCTGCCTGAGGTCTTTGGCAACTTGAACTCTGTCATGTGTG TGGAGGGTGAAGCTGGAAGTGGAAAGACGGTCCTCCTGAAGAAAATAGCTTTTCTGTGGG CATCTGGATGCTGTCCCCTGTTAAACAGGTTCCAGCTGGTTTTCTACCTCTCCCTTAGTT CCACCAGACCAGACGAGGGGCTGGCCAGTATCATCTGTGACCAGCTCCTAGAGAAAGAAG GATCTGTTACTGAAATGTGCATGAGGAACATTATCCAGCAGTTAAAGAATCAGGTCTTAT TCCTTTTAGATGACTACAAAGAAATATGTTCAATCCCTCAAGTCATAGGAAAACTGATTC AAAAAAACCACTTATCCCGGACCTGCCTATTGATTGCTGTCCGTACAAACAGGGCCAGGG ACATCCGCCGATACCTAGAGACCATTCTAGAGATCAAAGCATTTCCCTTTTATAATACTG TCTGTATATTACGGAAGCTCTTTTCACATAATATGACTCGTCTGCGAAAGTTTATGGTTT ACTTTGGAAAGAACCAAAGTTTGCAGAAGATACAGAAAACTCCTCTCTTTGTGGCGGCGA TCTGTGCTCATTGGTTTCAGTATCCTTTTGACCCATCCTTTGATGATGTGGCTGTTTTCA AGTCCTATATGGAACGCCTTTCCTTAAGGAACAAAGCGACAGCTGAAATTCTCAAAGCAA CTGTGTCCTCCTGTGGTGAGCTGGCCTTGAAAGGGTTTTTTTCATGTTGCTTTGAGTTTA ATGATGATGATCTCGCAGAAGCAGGGGTTGATGAAGATGAAGATCTAACCATGTGCTTGA TGAGCAAATTTACAGCCCAGAGACTAAGACCATTCTACCGGTTTTTAAGTCCTGCCTTCC AAGAATTTCTTGCGGGGATGAGGCTGATTGAACTCCTGGATTCAGATAGGCAGGAACATC AAGATTTGGGACTGTATCATTTGAAACAAATCAACTCACCCATGATGACTGTAAGCGCCT ACAACAATTTTTTGAACTATGTCTCCAGCCTCCCTTCAACAAAAGCAGGGCCCAAAATTG TGTCTCATTTGCTCCATTTAGTGGATAACAAAGAGTCATTGGAGAATATATCTGAAAATG ATGACTACTTAAAGCACCAGCCAGAAATTTCACTGCAGATGCAGTTACTTAGGGGATTGT GGCAAATTTGTCCACAAGCTTACTTTTCAATGGTTTCAGAACATTTACTGGTTCTTGCCC TGAAAACTGCTTATCAAAGCAACACTGTTGCTGCGTGTTCTCCATTTGTTTTGCAATTCC TTCAAGGGAGAACACTGACTTTGGGTGCGCTTAACTTACAGTACTTTTTCGACCACCCAG AAAGCTTGTCATTGTTGAGGAGCATCCACTTCCCAATACGAGGAAATAAGACATCACCCA GAGCACATTTTTCAGTTCTGGAAACATGTTTTGACAAATCACAGGTGCCAACTATAGATC AGGACTATGCTTCTGCCTTTGAACCTATGAATGAATGGGAGCGAAATTTAGCTGAAAAAG AGGATAATGTAAAGAGCTATATGGATATGCAGCGCAGGGCATCACCAGACCTTAGTACTG GCTATTGGAAACTTTCTCCAAAGCAGTACAAGATTCCCTGTCTAGAAGTCGATGTGAATG ATATTGATGTTGTAGGCCAGGATATGCTTGAGATTCTAATGACAGTTTTCTCAGCTTCAC AGCGCATCGAACTCCATTTAAACCACAGCAGAGGCTTTATAGAAAGCATCCGCCCAGCTC TTGAGCTGTCTAAGGCCTCTGTCACCAAGTGCTCCATAAGCAAGTTGGAACTCAGCGCAG CCGAACAGGAACTGCTTCTCACCCTGCCTTCCCTGGAATCTCTTGAAGTCTCAGGGACAA TCCAGTCACAAGACCAAATCTTTCCTAATCTGGATAAGTTCCTGTGCCTGAAAGAACTGT CTGTGGATCTGGAGGGCAATATAAATGTTTTTTCAGTCATTCCTGAAGAATTTCCAAACT TCCACCATATGGAGAAATTATTGATCCAAATTTCAGCTGAGTATGATCCTTCCAAACTAG TAAAATTAATTCAAAATTCTCCAAACCTTCATGTTTTCCATCTGAAGTGTAACTTCTTTT CGGATTTTGGGTCTCTCATGACTATGCTTGTTTCCTGTAAGAAACTCACAGAAATTAAGT TTTCGGATTCATTTTTTCAAGCCGTCCCATTTGTTGCCAGTTTGCCAAATTTTATTTCTC TGAAGATATTAAATCTTGAAGGCCAGCAATTTCCTGATGAGGAAACATCAGAAAAATTTG CCTACATTTTAGGTTCTCTTAGTAACCTGGAAGAATTGATCCTTCCTACTGGGGATGGAA TTTATCGAGTGGCCAAACTGATCATCCAGCAGTGTCAGCAGCTTCATTGTCTCCGAGTCC TCTCATTTTTCAAGACTTTGAATGATGACAGCGTGGTGGAAATTGCCAAAGTAGCAATCA GTGGAGGTTTCCAGAAACTTGAGAACCTAAAGCTTTCAATCAATCACAAGATTACAGAGG AAGGATACAGAAATTTCTTTCAAGCACTGGACAACATGCCAAACTTGCAGGAGTTGGACA TCTCCAGGCATTTCACAGAGTGTATCAAAGCTCAGGCCACAACAGTCAAGTCTTTGAGTC AATGTGTGTTACGACTACCAAGGCTCATTAGACTGAACATGTTAAGTTGGCTCTTGGATG CAGATGATATTGCATTGCTTAATGTCATGAAAGAAAGACATCCTCAATCTAAGTACTTAA CTATTCTCCAGAAATGGATACTGCCGTTCTCTCCAATCATTCAGAAATAAAAGATTCAGC TAAAAACTGCTGAATCAATAATTTGTCTTGGGGCATATTGAGGATGTAAAAAAAGTTGTT GATTAATGCTAAAAACCAAATTATCCAAAATTATTTTATTAAATATTGCATACAAAAGAA AATGTGTAAGGCTTGCTAAAAAACAAAACAAAACAAAACACAGTCCTGCATACTCACCAC CAAGCTCAAGAAATAAATCATCACCAATACCTTTGAGGTCCCTGAGTAATCCACCCCAGC TAAAGGCAAACCCTTCAATCAAGTTTATACAGCAAACCCTCCATTGTCCATGGTCAACAG GGAAGGGGTTGGGGACAGGTCTGCCAATCTATCTAAAAGCCACAATATGGAAGAAGTATT CAATTTATATAATAAATGGCTAACTTAACGGTTGAATCACTTTCATACATGGATGAAACG GGTTTAACACAGGATCCACATGAATCTTCTGTGGGCCAAGAGATGTTCCTTAATCCTTGT AGAACCTGTTTTCTATATTGAACTAGCTTTGGTACAGTAGAGTTAACTTACTTTCCATTT ATCCACTGCCAATATAAAGAGGAAACAGGGGTTAGGGAAAAATGACTTCATTCCAGAGGC TTCTCAGAGTTCAACATATGCTATAATTTAGAATTTTCTTATGAATCCACTCTACTTGGG TAGAAAATATTTTATCTCTAGTGATTGCATATTATTTCCATATCATAGTATTTCATAGTA TTATATTTGATATGAGTGTCTATATCAATGTCAGTGTCCAGAATTTCGTTCCTACCAGTT AAGTAGTTTTCTGAACGGCCAGAAGACCATTCGAAATTCATGATACTACTATAAGTTGGT AAACAACCATACTTTTATCCTCATTTTTATTCTCACTAAGAAAAAAGTCAACTCCCCTCC CCTTGCCCAAGTATGAAATATAGGGACAGTATGTATGGTGTGGTCTCATTTGTTTAGAAA ACCACTTATGACTGGGTGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAG GCGGGCGAATCATTTGAGGTGAGGAATTCGAGACCAGCCTGGCCAGCATGGTGAAACCCC ATCTCTACTAAAAATACAAAAATTAGCCAGGTGTGGTGGCACATGCCTGTAGTCCCAGCC ACTAGGGCGGCTGAGACGCAAGACTTGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCC AAGATGGCGCCACTGCATTCCAGCCTGGGCAACAGAGCAAGACCCTGTCTGTCTCAAAAC AAAAAACAAAACCACTTATATTGCTAGCTACATTAAGAATTTCTGAATATGTTACTGAGC TTGCTTGTGGTAACCATTTATAATATCAGAAAGTATATGTACACCAAAACATGTTGAACA TCCATGTTGTACAACTGAAATATAAATAATTTTGTCAATTATACCTAAATAAAACTGGAA AAAAAAAAAAAAAAAA >OriGene 5' read for NM_004536 unedited
GGCCATTTCGAAAATACGACTCCTATAGGGCGGCCGCGAATTCGGCACGAGAAAGGACGG ACAGAGCATTTGTTCTTCAGCCACATACTTTCCTTCCACTGGCCAGCATTCTCCTCTATT AGACTAGAACTGTGGATAAACCTCAGAAAATGGCCACCCAGCAGAAAGCCTCTGACGAGA GGATCTCCCAGTTTGATCACAATTTGCTGCCAGAGCTGTCTGCTCTTCTGGGCCTAGATG CAGTTCAGTTGGCAAAGGAACTAGAAGAAGAGGAGCAGAAGGAGCGAGCAAAAATGCAGA AAGGCTACAACTCTCAAATGCGCAGTGAAGCAAAAAGGTTAAAGACTTTTGTGACTTATG AGCCGTACAGCTCATGGATACCACAGGAGATGGCGGCCGCTGGGTTTTACTTCACTGGGG TAAAATCTGGGATTCAGTGCTTCTGCTGTAGCCTAATCCTCTTTGGTGCCGGCCTCACGA GACTCCCCATAGAAGACCACAAGAGGTTTCATCCAGATTGTGGGTTCCTTTTGAACAAGG ATGTTGGTAACATTGCCAAGTACGACATAAGGGTGAAGAATCTGAAGAGCAGGCTGAGAG GAGGTAAAATGAGGTACCAAGAAGAGGAGGCTAGACTTGCATCCTTCAGGAACTGGCCAT TTTATGTCCAAGGGATATCCCCTTGTGTGCTCTCAGAGGCTGGCTTTGTCTTTACAGGTA AACAGGACACGGTACAGTGTTTTTCCTGTGGTGGATGTTTAGGAAATTGGGAAGAAGAGA TGATCCTTGGAAGGAACATGCCAAATGGTTCCCCAAATGTGAATTTCTTCGGAGTAGAAA TCCTCAGAGGAAATTACCCAGTATATTTCAAAGCTACAAGGATTTGTTGACATAACGGAA GACATTTTGTGAATTCCTGGGTCAGAGAAGAATTACCTATGGCATCAGCTTATTGCAATG ACCAGCATC >OriGene 3' read for NM_004536 unedited
CAATAATGGCACTTCCGGGCCGGAGAGCACTGGGGAGGGGTCACAGGGATGCCCCCGGGA TCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTT TTTTCCAGTTTTATTTAGGTATAATTGACAAAATTATTTATATTTCAGTTGTACAACATG GATGTTCAACATGTTTTGGTGTACATATACTTTCTGATATTATAAATGGTTACCACAAGC AAGCTCAGTAACATATTCAGAAATTCTTAATGTAGCTAGCAATATAAGTGGTTTTGTTTT TTGTTTTGAGACAGACAGGGTCTTGCTCTGTTGCCCAGGCTGGAATGCAGTGGCGCCATC TTGGCTCACTGCACCTTTGCCTCCAGGGTTCAAGCAAGTATTGCGTTTCAGCCTCCCTAT TGGCTGGGACTACAGGCATGTGCCACCACACCTGGCTAATTTTTGTATTTTTAATAGAGA TGGGGTTTCACCATGCTGGCCACGCTGGCCTCTAATTCCTTTCCTAAAATGATTCACCGG ACTCAGCCTTACCAAAGTGCTGGGATTACACGGTGTGAGCCACCTCACCTAACATTCTTG GTTTCCTAAACAAATGAAACCACACCTTACAAACTGTCCTATTTTTATACTTGGCAAGGA GAGGGGAGTTGCTTTTTTCTAAAAGAAATAGAAATGAGGAAAAAAGTATGGTTGTTTACC C |
| Restriction Sites | Please inquire |
| ACCN | NM_004536 |
| Insert Size | 6000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | no |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004536.1, NP_004527.1 |
| RefSeq Size | 6133 bp |
| RefSeq ORF | 4212 bp |
| Locus ID | 4671 |
| UniProt ID | Q13075 |
| Protein Families | Druggable Genome |
| Protein Pathways | NOD-like receptor signaling pathway |
| Gene Summary | This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Nov 2016] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Both variants 1 and 3 encode the same protein. |
Citations (4)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Neuronal apoptosis inhibitory protein (NAIP) localizes to the cytokinetic machinery during cell division
,Abadía-Molina, F;Morón-Calvente, V;Baird, SD;Shamim, F;Martín, F;MacKenzie, A;,
Sci Rep
,PubMed ID 28059125
[NAIP]
|
|
Cutting Edge: Inflammasome Activation in Primary Human Macrophages Is Dependent on Flagellin
,Kortmann, J;Brubaker, SW;Monack, DM;,
J. Immunol.
,PubMed ID 26109648
[NAIP]
|
|
Formation and Structure of a NAIP5-NLRC4 Inflammasome Induced by Direct Interactions with Conserved N- and C-terminal Regions of Flagellin
,Els F. Halff, Christoph A. Diebolder, Marian Versteeg, Arie Schouten, T. Harma C. Brondijk, and Eric G. Huizinga,
J. Biol. Chem., Nov 2012; 287: 38460 - 38472.
[Naip]
|
|
NAIP and Ipaf Control Legionella pneumophila Replication in Human Cells
,Slevogt, Philippe Dje N'Guessan, Stefan Günther, Bernd Schmeck, Stefan Hippenstiel, Antje Flieger, Norbert Suttorp, and Bastian Opitz,
J. Immunol., May 2008; 180: 6808 - 6815
[NAIP]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216758 | NAIP (Myc-DDK-tagged)-Human NLR family, apoptosis inhibitory protein (NAIP), transcript variant 1 |
CNY 13,970.00 |
|
| RC216758L3 | Lenti ORF clone of Human NLR family, apoptosis inhibitory protein (NAIP), transcript variant 1, Myc-DDK-tagged |
CNY 15,870.00 |
|
| RG216758 | NAIP (tGFP-tagged) - Human NLR family, apoptosis inhibitory protein (NAIP), transcript variant 1 |
CNY 16,000.00 |
Customer
Reviews
Loading...
