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Desmoglein 1 (DSG1) (NM_001942) Human Untagged Clone
CAT＃: SC303097
DSG1 (untagged)-Human desmoglein 1 (DSG1)
CNY 7,312.00
货期*
现货
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CDHF4; DG1; DSG; EPKHE; EPKHIA; PPKS1; SPPK1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001942 edited
TAAGAACATCTACTGAGAAATTATTTTAATCAGACACCAGCTGAGTGGGAGAAAGAAAAA GAACAGAGAAGAACAAACAAAACTCCCTTGGTCTTGGATGTAAGAGAATCCAGCAGAGAT GGACTGGAGTTTCTTCAGAGTAGTTGCAATGCTGTTCATTTTTCTGGTGGTGGTAGAAGT TAACAGTGAATTCCGAATCCAGGTAAGAGATTATAACACTAAAAATGGCACCATCAAATG GCATTCAATCCGAAGGCAGAAACGTGAATGGATCAAGTTCGCAGCAGCCTGTCGTGAAGG TGAAGACAACTCAAAGAGGAACCCAATCGCCAAAATTCACTCAGATTGTGCTGCAAACCA GCAAGTTACATACCGCATCTCTGGAGTAGGAATTGATCAGCCACCATATGGGATCTTTGT CATTAATCAGAAAACTGGTGAAATTAATATAACATCCATAGTTGATCGAGAGGTCACTCC TTTCTTCATTATCTACTGCCGAGCTCTGAACTCAATGGGCCAAGATTTAGAGAGGCCTCT AGAGCTCAGAGTCAGGGTTTTGGATATAAATGACAACCCTCCAGTGTTTTCAATGGCTAC ATTTGCAGGACAAATAGAAGAAAATTCTAATGCAAATACACTGGTGATGATACTCAATGC TACTGACGCAGATGAACCGAACAATTTGAACTCAAAAATAGCCTTCAAGATTATAAGACA AGAACCTTCAGATTCACCAATGTTTATTATCAACAGAAATACTGGAGAAATTCGAACGAT GAATAATTTTCTAGACAGAGAGCAATACGGCCAGTATGCTCTTGCTGTAAGAGGCTCTGA CCGAGATGGCGGGGCAGATGGCATGTCAGCGGAATGTGAGTGCAACATTAAAATCCTCGA TGTCAATGATAATATCCCTTACATGGAACAGTCTTCATATACCATAGAAATTCAAGAAAA TACTCTAAATTCAAATTTGCTCGAGATTAGAGTAATTGATTTGGATGAAGAGTTCTCAGC TAACTGGATGGCAGTAATTTTCTTTATCTCTGGAAATGAAGGAAATTGGTTTGAGATAGA AATGAATGAAAGAACAAATGTGGGAATTTTAAAGGTTGTTAAGCCCTTAGATTATGAAGC TATGCAGAGTCTGCAACTCAGTATTGGTGTCAGAAATAAAGCTGAATTTCATCATTCAAT TATGTCTCAATATAAACTGAAAGCATCTGCAATTTCTGTGACTGTGTTAAATGTAATTGA AGGCCCAGTGTTTCGTCCAGGTTCAAAGACATATGTTGTAACTGGTAATATGGGATCAAA TGATAAAGTGGGAGACTTTGTAGCTACTGACCTGGACACAGGTAGACCTTCAACGACTGT TAGGTATGTAATGGGAAATAATCCAGCTGACCTGCTAGCTGTTGATTCAAGAACAGGCAA ACTCACTTTGAAAAATAAAGTTACCAAGGAACAGTACAATATGCTCGGAGGAAAATACCA AGGAACGATTCTCTCTATAGATGATAATCTTCAAAGAACTTGCACTGGTACAATTAATAT TAACATTCAAAGTTTTGGTAATGACGACAGGACTAATACAGAGCCGAACACTAAAATTAC TACCAATACTGGCAGACAAGAAAGTACTTCTTCCACTAACTATGATACCAGCACAACTTC TACTGACTCTAGCCAAGTATATTCTTCTGAACCCGGAAACGGAGCCAAAGATTTGTTATC AGACAATGTACATTTTGGTCCTGCTGGCATTGGACTCCTCATCATGGGATTCTTGGTCTT AGGATTGGTCCCATTTTTGATGATCTGTTGTGATTGTGGAGGTGCTCCTCGTAGTGCAGC TGGCTTTGAGCCTGTTCCCGAATGTTCAGATGGAGCAATTCATTCATGGGCAGTAGAAGG ACCACAGCCTGAACCCAGGGATATAACCACTGTCATACCACAAATACCACCTGATAACGC AAATATAATTGAATGCATTGACAACTCAGGAGTTTATACAAATGAGTATGGTGGCAGAGA AATGCAAGATCTGGGAGGAGGAGAGAGAATGACAGGATTTGAACTAACAGAGGGAGTTAA AACTTCAGGAATGCCTGAGATATGTCAAGAATACTCTGGAACATTAAGAAGAAATTCTAT GAGGGAATGTAGAGAAGGAGGTCTGAATATGAATTTCATGGAAAGCTACTTCTGTCAGAA AGCATATGCTTACGCAGATGAAGATGAAGGACGCCCATCTAATGACTGTTTGCTCATATA TGACATCGAAGGTGTAGGTTCCCCTGCTGGCTCTGTGGGTTGTTGTAGCTTCATTGGAGA AGACCTGGATGACAGCTTCTTGGATACCCTGGGACCTAAATTTAAGAAGTTGGCAGACAT CAGCCTAGGAAAAGAATCATATCCAGACCTTGATCCTTCTTGGCCACCACAAAGCACTGA ACCAGTTTGCCTTCCTCAGGAAACAGAGCCCGTTGTTAGTGGACACCCACCAATCTCCCC ACATTTCGGCACTACCACAGTAATTTCTGAGAGCACCTATCCCTCGGGACCTGGTGTACT GCATCCTAAGCCTATTCTCGATCCTCTGGGCTATGGTAATGTCACTGTGACCGAGTCTTA CACCACCTCTGACACTCTGAAGCCCTCTGTGCACGTTCACGATAACCGACCAGCATCAAA CGTGGTAGTGACAGAGAGAGTGGTCGGCCCAATCTCTGGCGCTGATTTGCATGGAATGTT AGAGATGCCTGACTTGCGAGATGGGTCGAATGTTATAGTGACAGAAAGGGTAATAGCACC AAGCTCTAGTCTACCCACCTCTCTGACTATCCATCATCCTAGAGAGTCTTCAAATGTGGT AGTGACAGAAAGAGTAATCCAACCAACTTCCGGCATGATAGGTAGTCTGAGTATGCACCC CGAGTTAGCCAATGCCCACAATGTCATTGTGACAGAGAGGGTTGTTTCTGGTGCTGGCGT AACTGGAATTAGTGGCACCACTGGGATCAGCGGTGGCATAGGCAGCAGTGGCCTGGTTGG CACCAGCATGGGTGCTGGGAGCGGTGCCCTGAGTGGAGCTGGCATAAGTGGTGGTGGCAT TGGCCTGAGCAGCTTGGGAGGGACAGCCAGCATTGGCCACATGAGGAGTTCCTCTGACCA TCACTTTAACCAAACCATTGGGTCCGCCTCCCCTAGCACAGCTCGAAGTCGAATCACAAA GTATAGTACCGTGCAATATAGCAAGTAGTCAGGACCCCAGCTCACTTTTTCATAGTCATT GTGGTTTAGATCCAATTCCCACCACTAAAAAACTAACAATGTGATTTATAACGCACAACT TCGTGCTCAGGTCATCTAGGAGCAAGGTGAGAAATCACAATGAGAAAAATAAATGGAAAC ACCACTGCTAGGGGAGAGCTCTCCTTAGCATTCATAAACTTTTCTCTTATATTAGGACTA AGGAACTAAAACTTGAGGCAGAGTCTTCTTTGTGCCTGAGTGGCCTGTAGTCCATCTCCA GCATGTAACTGGCCTTACGATGGCAATTGGCATCATTCTCCTTGCTCTGTTTTGCTTTTC CATATAGCTCGAGCAAAATTCAAAAAGAACTAAATATGCAATATATGTTCATATCTATGG GAAAAATCTAAAATGTGTGCCAGATGCCCTGTTGGTTTCACAGATAACATAAATAAAAAT TCAACCACAGATTTATACAAGGGTTAACCATTTTTTTTAAGTTTGACTACATAGTCAAGT CCACAAGCCATCAAGCACTCCTACCTTAATTATTGCACTAGAGAAAATAAATTCCAAATT AGGAAGTGTTTCCTAGGAGGAAAATTCCATTAGAGAGTGGCAATAGGATGAGGTTTCTTC AGGGTAAACTAGCAATGCCTGAGCCTGAACCTTAATGTGGGGCCTCAGTTAATATCCCTG TGGAGTCAAGGATTCTTCTGATTCTAGTGTGTGTTTAGTGATAGATGTAGTCTTGACGAA TATTGCTTACTGGTGAGGTTGAGGAATATCACACTCGTCTTTCCCTTTACCACTGTGGTT TTGACTTAAGAAAGCAAAACTCACTAAGTTTACTTCTCGAATTGAAGCAAGTGAGGCCTG ACATGGTTGTCATCACTAGTGGCAAATGACCTTCCAAGTAAGCAGATGGGAACTGAATTG TGTTTTCAGGTTTTGTTTTTAGTAGGTGATATTCATTCGTATCCAGCTCTTTATTACATA GCTCTGAAGTTAAAATGATTTACATAGGCCGAGCTGTGGACAAAAAAAAAGAAGCAGCAG CTTGTAGTATGCTTAAGCTTTGGGGAATTTTTTTTTAAGGGGATCTAAAAAAATGTTTTT AGAACATGTAAAATGTTTAATGGTGAAAGTTGGAAAAGAATTCTTCTGTAAAGTAATACC ATGCTAATTATTCGCTTTTAGTAAGTAAAGTAGTGGTTGCTTTAGCAAACCTCTGCTGCC ATTTTGCAGGAATCAACCAGGAACCTTTAGCAGAATTGACAATATGGTGTTGATAAGCAT GAAATAATAATAGAAACCTATTCTGCTAGTTTATCTCACCCTCTAATTTTTCTCACTAGC ATAAATTTTAAATTCCTGATTTGATTTGTCAATAAGATCTTGGCTTATATATGCTGATTT ATAGGTAGTGTCCAAATTATATAGTATAACATATTTTTCTAGTTTCAAAATTTAGTAATG TCCTATTTATGATATATCATTTCTGTGTGTTTGCTATGTAGTATTACCCAATTAAAAATC TCTAAAAAGAATTAAAGCATTCTAAGAAAAAGGTAAATTTACTATTGCATGGTACAGAAA TTTTTTCTTTCTTAAATACAATGTTACTATAAGCTCACTAAAATGAAACTCTATATGACA AAATAAAATTAGAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_001942 unedited
NGAGTTTTTATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACCAGGTAAGAAC ATCTACTGAGAAATATTTTAATCAGACACCAGCTGAGTGGGAGAAAGAAAAAGAACAGAG AAGAACAAACAAAACTCCCTTGGTCTTGGATGTAAGAGAATCCAGCAGAGATGGACTGGA GTTTCTTCAGAGTAGTTGCAATGCTGTTCATTTTTCTGGTGGTGGTAGAAGTTAACAGTG AATTCCGAATCCAGGTAAGAGATTATAACACTAAAAATGGCACCATCAAATGGCATTCAA TCCGAAGGCAGAAACGTGAATGGATCAAGTTCGCAGCAGCCTGTCGTGAAGGTGAAGACA ACTCAAAGAGGAACCCAATCGCCAAAATTCACTCAGATTGTGCTGCAAACCAGCAAGTTA CATACCGCATCTCTGGAGTAGGAATTGATCAGCCACCATATGGGATCTTTGTCATTAATC AGAAAACTGGTGAAATTAATATAACATCCATAGTTGATCGAGAGGTCACTCCTTTCTTCA TTATCTACTGCCGAGCTCTGAACTCANATGGNGGCCCAAGATTTAGAGAGGCCTCTAGAG CTCAGAGTCAGGGTTTTTGGATATAAATGANCACCCTNCAGTGTTTTCAATGGCTACATT TGCAGGGACAAATAGAGAAAATTCTATGCAAATACACTGGTGATGATACTCAATGCTACT GACGCAGATGAACCCNGACATTTGAACTCAAAATAAGCCTTTCAGATATTAGACAAGNAC CTTCAGATTCACCATGTTTATTTATCACAGAAATACTGGAAAAATTCGAACGATGAATAA TTTTCTTAGACAGAAAGCCATACGGGCCAGTATGCTTTTGCTGTAAAAGGCTCTGACCGA C |
| Restriction Sites | Please inquire |
| ACCN | NM_001942 |
| Insert Size | 5000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | There is 1 nucleotide difference between the OriGene clone and the NCBI reference ORF. OriGene considers these to be polymorphisms and to reflect the natural differences between individuals. These result in the substituion of 1 aa. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001942.1, NP_001933.1 |
| RefSeq Size | 4512 bp |
| RefSeq ORF | 3150 bp |
| Locus ID | 1828 |
| UniProt ID | Q02413 |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015] |
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