BAI1 (ADGRB1) (NM_001702) Human Untagged Clone
CAT#: SC303054
BAI1 (untagged)-Human brain-specific angiogenesis inhibitor 1 (BAI1)
CNY 10,848.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | BAI1; GDAIF |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF sequence for NM_001702 edited
ATGAGGGGCCAGGCCGCCGCCCCGGGCCCCGTCTGGATCCTCGCCCCGCTGCTACTGCTG CTGCTGCTGCTGGGACGCCGCGCGCGGGCGGCCGCCGGAGCAGACGCGGGGCCCGGGCCC GAGCCGTGCGCCACGCTGGTGCAGGGAAAGTTCTTCGGCTACTTCTCCGCGGCCGCCGTG TTCCCGGCCAACGCCTCGCGCTGCTCCTGGACGCTACGCAACCCGGACCCGCGGCGCTAC ACTCTCTACATGAAGGTGGCCAAGGCGCCCGTGCCCTGCAGCGGCCCCGGCCGCGTGCGC ACCTACCAGTTCGACTCCTTCCTCGAGTCCACGCGCACCTACCTGGGCGTGGAGAGCTTC GACGAGGTGCTGCGGCTCTGCGACCCCTCCGCACCCCTGGCCTTCCTGCAGGCCAGCAAG CAGTTCCTGCAGATGCGGCGCCAGCAGCCGCCCCAGCACGACGGGCTCCGGCCCCGGGCC GGGCCGCCGGGCCCCACCGACGACTTCTCCGTGGAGTACCTGGTGGTGGGGAACCGCAAC CCCAGCCGTGCCGCCTGCCAGATGCTGTGCCGCTGGCTGGACGCGTGTCTGGCCGGTAGT CGCAGCTCGCACCCCTGCGGGATCATGCAGACCCCCTGCGCCTGCCTGGGCGGCGAGGCG GGCGGCCCTGCCGCGGGACCCCTGGCCCCCCGCGGGGATGTCTGCTTGAGAGATGCGGTG GCTGGTGGCCCTGAAAACTGCCTCACCAGCCTGACCCAGGACCGGGGCGGGCACGGCGCC ACAGGCGGCTGGAAGCTGTGGTCCCTGTGGGGCGAATGCACGCGGGACTGCGGGGGAGGC CTCCAGACGCGGACGCGCACCTGCCTGCCCGCGCCGGGCGTGGAGGGCGGCGGCTGCGAG GGGGTGCTGGAGGAGGGTCGCCAGTGCAACCGCGAGGCCTGCGGCCCCGCTGGGCGCACC AGCTCCCGGAGCCAGTCCCTGCGGTCCACAGATGCCCGGCGGCGCGAGGAGCTGGGGGAC GAGCTGCAGCAGTTTGGGTTCCCAGCCCCCCAGACCGGTGACCCAGCAGCCGAGGAGTGG TCCCCGTGGAGCGTGTGCTCCAGCACCTGCGGCGAGGGCTGGCAGACCCGCACGCGCTTC TGCGTGTCCTCCTCCTACAGCACGCAGTGCAGCGGACCCCTGCGCGAGCAGCGGCTGTGC AACAACTCTGCCGTGTGCCCAGTGCATGGTGCCTGGGATGAGTGGTCGCCCTGGAGCCTC TGCTCCAGCACCTGTGGCCGTGGCTTTCGGGATCGCACGCGCACCTGCAGGCCCCCCCAG TTTGGGGGCAACCCCTGTGAGGGCCCTGAGAAGCAAACCAAGTTCTGCAACATTGCCCTG TGCCCTGGCCGGGCAGTGGATGGAAACTGGAATGAGTGGTCGAGCTGGAGCGCCTGCTCC GCCAGCTGCTCCCAGGGCCGACAGCAGCGCACGCGTGAATGCAACGGGCCTTCCTACGGG GGTGCGGAGTGCCAGGGCCACTGGGTGGAGACCCGAGACTGCTTCCTGCAGCAGTGCCCA GTGGATGGCAAGTGGCAGGCCTGGGCGTCATGGGGCAGTTGCAGCGTCACGTGTGGGGCT GGCAGCCAGCGACGGGAGCGTGTCTGCTCTGGGCCCTTCTTCGGGGGAGCAGCCTGCCAG GGCCCCCAGGATGAGTACCGGCAGTGCGGCACCCAGCGGTGTCCCGAGCCCCATGAGATC TGTGATGAGGACAACTTTGGTGCTGTGATCTGGAAGGAGACCCCAGCGGGAGAGGTGGCT GCTGTCCGGTGTCCCCGCAACGCCACAGGACTCATCCTGCGACGGTGTGAGCTGGACGAG GAAGGCATCGCCTACTGGGAGCCCCCCACCTACATCCGCTGTGTTTCCATTGACTACAGA AACATCCAGATGATGACCCGGGAGCACCTGGCCAAGGCTCAGCGAGGGCTGCCTGGGGAG GGGGTCTCGGAGGTCATCCAGACACTGGTGGAGATCTCTCAGGACGGGACCAGCTACAGT GGGGACCTGCTGTCCACCATCGATGTCCTGAGGAACATGACAGAGATTTTCCGGAGAGCG TACTACAGCCCCACCCCTGGGGACGTACAGAACTTTGTCCAGATCCTTAGCAACCTGTTG GCAGAGGAGAATCGGGACAAGTGGGAGGAGGCCCAGCTGGCGGGCCCCAACGCCAAGGAG CTGTTCCGGCTGGTGGAGGACTTTGTGGACGTCATCGGCTTCCGCATGAAGGACCTGAGG GATGCATACCAGGTGACAGACAACCTGGTTCTCAGCATCCATAAGCTCCCAGCCAGCGGA GCCACTGACATCAGCTTCCCCATGAAGGGCTGGCGGGCCACGGGTGACTGGGCCAAGGTG CCAGAGGACAGGGTCACTGTGTCCAAGAGTGTCTTCTCCACGGGGCTGACAGAGGCCGAT GAAGCATCCGTGTTTGTGGTGGGCACCGTGCTCTACAGGAACCTGGGCAGCTTCCTGGCC CTGCAGAGGAACACGACCGTCCTGAATTCTAAGGTGATCTCCGTGACTGTGAAACCCCCG CCTCGCTCCCTGCGCACACCCTTGGAGATCGAGTTTGCCCACATGTATAATGGCACCACC AACCAGACCTGTATCCTGTGGGATGAGACGGATGTACCCTCCTCCTCCGCCCCCCCGCAG CTCGGGCCCTGGTCGTGGCGCGGCTGCCGCACGGTGCCCCTCGACGCCCTCCGGACGCGC TGCCTCTGTGACCGGCTCTCCACCTTCGCCATCTTAGCCCAGCTCAGCGCCGACGCGAAC ATGGAGAAGGCGACTCTGCCGTCGGTGACGCTCATCGTGGGCTGTGGCGTGTCCTCTCTC ACCCTGCTCATGCTGGTCATCATCTACGTGTCCGTGTGGAGGTACATTCGCTCAGAGCGT TCTGTCATCCTCATCAACTTCTGCCTGTCCATCATCTCCTCCAATGCCCTCATCCTCATC GGGCAGACCCAGACCCGCAACAAGGTGGTGTGCACGCTGGTGGCCGCCTTCCTGCACTTC TTCTTCCTGTCCTCCTTCTGCTGGGTGCTCACCGAGGCCTGGCAGTCCTACATGGCGGTG ACGGGCCACCTCCGGAACCGCCTCATCCGCAAGCGCTTCCTCTGCCTGGGCTGGGGGCTC CCTGCACTGGTTGTGGCCATTTCTGTGGGATTCACCAAGGCCAAAGGGTACAGCACCATG AACTACTGCTGGCTCTCCCTGGAGGGGGGACTGCTCTATGCCTTCGTGGGACCTGCCGCT GCCGTTGTGCTGGTGAACATGGTCATTGGGATCCTGGTGTTCAACAAGCTCGTGTCCAAA GACGGCATCACGGACAAGAAGCTGAAGGAGCGGGCAGGGGCCTCCCTGTGGAGCTCCTGC GTGGTGCTGCCGCTGCTGGCGCTGACCTGGATGTCGGCTGTGCTCGCCGTCACCGACCGC CGCTCCGCCCTCTTCCAGATCCTCTTCGCTGTCTTCGACTCGCTGGAGGGCTTCGTCATC GTCATGGTGCACTGTATCCTCCGTAGAGAGGTCCAGGACGCTGTGAAATGCCGTGTGGTT GACCGGCAGGAGGAGGGCAACGGGGACTCAGGGGGCTCCTTCCAGAACGGCCACGCCCAG CTCATGACCGACTTCGAGAAGGACGTGGATCTGGCCTGTAGATCAGTGCTGAACAAGGAC ATCGCGGCCTGCCGCACTGCCACCATCACGGGCACACTGAAGCGGCCGTCTCTGCCCGAG GAGGAGAAGCTGAAGCTGGCCCATGCCAAGGGGCCGCCCACCAATTTCAACAGCCTGCCG GCCAACGTGTCCAAGCTGCACCTGCACGGCTCACCCCGCTATCCCGGCGGGCCCCTGCCC GACTTCCCCAACCACTCACTGACCCTCAAGAGGGACAAGGCGCCCAAGTCCTCCTTCGTC GGTGACGGGGACATCTTCAAGAAGCTGGACTCGGAGCTGAGCCGGGCCCAGGAGAAGGCT CTGGACACGAGCTACGTGATCCTGCCCACGGCCACGGCCACGCTGCGGCCCAAGCCCAAG GAGGAGCCCAAGTACAGCATCCACATTGACCAGATGCCGCAGACCCGCCTCATCCACCTC AGCACGGCCCCCGAGGCCAGCCTCCCCGCCCGCAGCCCGCCCTCCCGCCAGCCCCCCAGC GGCGGGCCCCCCGAGGCACCCCCTGCCCAGCCCCCACCGCCTCCGCCCCCACCGCCACCA CCTCCCCAGCAGCCCCTGCCCCCACCGCCCAATCTGGAGCCGGCACCCCCCAGCCTGGGG GATCCCGGGGAGCCTGCCGCCCATCCGGGACCCAGCACGGGGCCCAGCACCAAGAACGAG AATGTCGCCACCTTGTCTGTGAGCTCCCTGGAGCGGCGGAAGTCGCGGTATGCAGAACTG GACTTTGAGAAGATCATGCACACCCGGAAGCGGCACCAAGACATGTTCCAGGACCTGAAC CGGAAGCTGCAGCACGCAGCGGAGAAGGACAAGGAGGTGCTGGGGCCGGACAGCAAGCCG GAAAAGCAGCAGACGCCCAACAAGAGGCCCTGGGAGAGCCTCCGGAAAGCCCACGGGACG CCCACGTGGGTGAAGAAGGAGCTGGAGCCGCTGCAGCCGTCGCCGCTGGAGCTTCGCAGC GTGGAGTGGGAGAGGTCGGGCGCCACGATCCCGCTGGTGGGCCAGGACATCATCGACCTC CAGACCGAGGTCTGA |
Restriction Sites | Please inquire |
ACCN | NM_001702 |
Insert Size | 4800 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001702.1. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001702.1, NP_001693.1 |
RefSeq Size | 5535 bp |
RefSeq ORF | 4755 bp |
Locus ID | 575 |
UniProt ID | O14514 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | p53 signaling pathway |
Gene Summary | Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC224196 | BAI1 (Myc-DDK-tagged)-Human brain-specific angiogenesis inhibitor 1 (BAI1) |
CNY 10,840.00 |
|
RC224196L3 | Lenti ORF clone of Human brain-specific angiogenesis inhibitor 1 (BAI1), Myc-DDK-tagged |
CNY 17,670.00 |
|
RC224196L4 | Lenti ORF clone of Human brain-specific angiogenesis inhibitor 1 (BAI1), mGFP tagged |
CNY 17,670.00 |
|
RG224196 | BAI1 (tGFP-tagged) - Human brain-specific angiogenesis inhibitor 1 (BAI1) |
CNY 12,440.00 |