United States
Germany
Japan
United Kingdom
China
APXL (SHROOM2) (NM_001649) Human Untagged Clone
CAT＃: SC303052
SHROOM2 (untagged)-Human shroom family member 2 (SHROOM2)
CNY 10,450.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | APXL; HSAPXL |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC303052 representing NM_001649.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGAGGGCGCCGAGCCCCGCGCGCGGCCCGAGCGCCTGGCCGAGGCCGAGACGCGGGCGGCGGACGGC GGGCGCCTGGTGGAGGTGCAGCTGAGCGGCGGCGCCCCGTGGGGCTTCACCCTGAAGGGCGGCCGCGAG CACGGCGAGCCGCTGGTCATCACCAAGATTGAAGAGGGCAGTAAAGCCGCGGCGGTCGACAAGTTACTG GCTGGAGATGAGATCGTCGGCATCAATGACATTGGTCTCTCAGGGTTTAGACAGGAAGCGATTTGCCTG GTGAAGGGGTCCCATAAGACCCTGAAGCTGGTCGTCAAAAGGAGGAGCGAGCTGGGCTGGAGGCCTCAC TCCTGGCATGCCACCAAGTTCTCTGACAGCCACCCCGAGCTAGCGGCCTCCCCATTCACCTCCACCAGC GGCTGTCCTTCCTGGTCCGGCCGACACCACGCGAGTTCTTCCTCCCACGACCTGTCCAGTTCCTGGGAG CAGACGAACCTACAGCGCACCTTAGATCACTTCAGCTCCTTGGGGAGCGTTGACAGCCTGGACCACCCC TCCAGTCGCCTCTCGGTGGCCAAGTCCAACAGCAGCATCGACCACCTGGGCAGCCACAGCAAGCGCGAC TCGGCCTACGGCTCCTTCTCCACCAGCTCTAGCACTCCTGACCACACCTTGTCCAAAGCCGACACGTCC TCCGCAGAGAACATCCTCTACACTGTGGGCCTCTGGGAGGCTCCCAGGCAGGGTGGCCGGCAGGCCCAG GCCGCAGGCGACCCTCAGGGCTCGGAGGAGAAGCTCAGTTGTTTCCCGCCCAGGGTCCCCGGTGACAGC GGCAAAGGCCCCAGGCCAGAGTACAATGCCGAGCCCAAGCTGGCTGCCCCTGGGAGGTCCAATTTTGGG CCAGTCTGGTATGTTCCCGATAAGAAGAAAGCACCATCATCCCCACCTCCTCCCCCTCCCCCTCTCCGC AGTGACAGCTTTGCTGCCACCAAGAGCCACGAGAAGGCCCAGGGCCCTGTGTTCTCAGAGGCGGCTGCG GCACAGCACTTTACGGCCCTGGCCCAGGCTCAGCCTCGTGGTGACCGGAGACCAGAGCTCACCGATCGG CCTTGGAGGTCAGCACACCCGGGGAGCCTCGGGAAGGGATCGGGAGGCCCGGGCTGCCCACAGGAGGCC CACGCAGACGGCAGCTGGCCGCCCTCCAAGGATGGAGCTTCCAGTAGGCTGCAGGCCTCTCTGTCCAGC TCAGATGTGCGCTTCCCTCAGTCTCCTCATAGCGGCCGACACCCTCCCCTATACAGCGACCACAGCCCC CTCTGTGCTGACAGCCTTGGGCAGGAGCCAGGGGCTGCCAGCTTCCAGAACGACAGCCCTCCTCAGGTG AGGGGGCTCAGCAGCTGTGACCAGAAGCTGGGGAGCGGCTGGCAGGGTCCCCGGCCCTGTGTGCAGGGA GACCTGCAAGCAGCACAGCTCTGGGCGGGATGCTGGCCTTCTGACACAGCCCTTGGAGCCCTCGAGAGT CTTCCCCCACCCACGGTGGGCCAGAGCCCACGCCATCACCTACCTCAGCCTGAGGGTCCTCCGGATGCC CGCGAGACAGGACGGTGTTACCCGCTGGACAAAGGGGCCGAGGGCTGCTCCGCGGGAGCCCAGGAGCCT CCCAGGGCCAGCCGTGCAGAAAAAGCCAGCCAGAGGCTGGCAGCCAGCATCACGTGGGCAGATGGGGAG AGCAGCAGGATCTGCCCGCAGGAGACGCCCCTGTTGCACTCCCTGACCCAGGAGGGGAAGCGCCGGCCT GAGAGCAGTCCAGAGGACAGCGCCACCAGACCGCCACCGTTCGACGCCCACGTGGGCAAGCCCACCCGA AGAAGCGACCGCTTTGCCACCACCCTGCGGAATGAGATCCAGATGCATAGAGCCAAGCTGCAGAAGAGC CGGAGCACAGTGGCTCTGACTGCAGCAGGGGAGGCGGAGGATGGCACCGGCCGCTGGAGGGCCGGGTTG GGAGGTGGCACCCAGGAAGGACCCCTCGCTGGCACCTATAAAGACCACCTGAAAGAGGCCCAAGCCCGG GTCCTGAGGGCCACGTCCTTCAAGCGCCGCGACTTGGACCCCAACCCAGGAGACCTATACCCGGAGTCA CTGGAACACCGGATGGGGGATCCAGACACTGTCCCCCACTTCTGGGAGGCAGGCCTGGCCCAGCCACCC TCATCTACAAGTGGCGGGCCCCACCCGCCCCGCATCGGAGGCCGGAGACGGTTCACAGCTGAGCAGAAA TTGAAGTCCTACTCGGAACCTGAGAAGATGAACGAGGTGGGCCTCACGAGGGGCTACAGTCCTCACCAG CACCCCAGGACATCTGAGGATACTGTGGGCACGTTTGCTGACAGGTGGAAGTTTTTTGAGGAAACGAGC AAACCTGTTCCCCAGAGGCCTGCCCAGAAGCAAGCTCTTCACGGAATCCCGAGAGACAAGCCAGAGAGG CCGCGGACAGCGGGCCGCACATGTGAGGGCACGGAGCCCTGGTCGCGCACCACCTCCCTTGGGGACAGC CTCAACGCTCACAGCGCAGCGGAGAAGGCAGGGACTTCAGACCTGCCGCGGAGGCTCGGCACCTTTGCA GAGTATCAGGCCTCTTGGAAGGAACAGAGGAAACCTCTGGAGGCCAGGAGCTCTGGGCGCTGCCACTCA GCGGATGACATCCTGGATGTGAGCCTGGACCCACAGGAGAGGCCGCAGCACGTTCATGGGAGGTCCCGG TCTTCACCGTCCACAGACCACTACAAGCAGGAAGCTTCTGTCGAACTGCGAAGGCAGGCAGGGGACCCC GGCGAGCCCAGAGAAGAGCTTCCCTCCGCAGTCCGGGCCGAGGAGGGACAGTCCACGCCGAGACAAGCA GATGCCCAGTGTCGGGAAGGCAGCCCAGGATCACAGCAGCACCCACCGAGTCAGAAGGCACCGAACCCA CCCACATTCTCTGAACTATCTCACTGCCGGGGAGCCCCAGAGCTGCCCCGGGAGGGCCGGGGCCGAGCG GGAACCCTACCTCGAGATTATAGATACTCGGAGGAGAGCACCCCAGCAGACTTGGGACCCCGAGCCCAG AGCCCTGGCTCACCCCTGCATGCTCGAGGACAAGACTCGTGGCCAGTGAGCTCAGCCCTGCTCTCCAAG AGGCCAGCCCCACAGAGGCCACCGCCACCCAAGCGCGAGCCCAGGAGATACAGGGCCACAGACGGCGCA CCTGCTGACGCCCCCGTGGGCGTCCTCGGCAGGCCCTTCCCAACGCCATCCCCTGCGTCCCTGGATGTG TATGTGGCCCGCCTGTCCCTCTCCCACAGCCCCTCTGTGTTCAGCAGTGCCCAGCCCCAGGACACCCCG AAGGCCACTGTCTGTGAGCGTGGAAGCCAGCATGTGAGCGGGGACGCATCACGTCCTCTGCCAGAAGCA CTGCTCCCTCCCAAGCAGCAGCACCTGCGCCTGCAGACGGCCACCATGGAGACCTCGCGCTCCCCCTCG CCCCAGTTCGCCCCCCAGAAACTGACGGACAAACCTCCCCTGCTCATCCAGGATGAGGATTCAACCAGA ATTGAGCGGGTGATGGACAACAACACCACGGTGAAGATGGTGCCCATCAAGATCGTGCACTCGGAGAGC CAGCCAGAGAAGGAGAGCCGCCAGAGCCTGGCATGCCCCGCCGAGCCACCTGCCCTGCCCCACGGGCTG GAGAAAGACCAGATCAAGACGCTGAGCACATCTGAGCAGTTCTACTCGCGCTTCTGTCTGTACACGCGG CAGGGTGCTGAGCCCGAGGCCCCACATAGGGCCCAGCCGGCTGAGCCCCAGCCCCTGGGCACCCAGGTG CCCCCCGAGAAAGACCGCTGCACCTCCCCTCCAGGGCTCAGCTACATGAAGGCCAAAGAGAAGACTGTG GAAGACCTGAAGTCGGAGGAGCTGGCCAGGGAGATCGTGGGGAAGGATAAGTCCCTGGCCGACATCCTG GATCCCAGTGTGAAGATCAAAACCACTATGGACTTGATGGAAGGCATCTTCCCCAAAGACGAGCACCTC CTGGAAGAAGCCCAGCAACGGAGGAAGCTGCTCCCCAAAATCCCCTCTCCTAGAAGCACAGAGGAGAGG AAAGAGGAGCCCAGCGTGCCTGCGGCCGTGTCCCTGGCCACCAATTCTACCTACTACAGCACGTCGGCC CCCAAGGCGGAGCTGCTGATCAAGATGAAGGACCTGCAGGAGCAGCAGGAGCACGAAGAGGATTCGGGA AGCGACTTGGACCACGACCTGTCGGTGAAGAAGCAGGAGCTCATCGAGAGCATCAGCCGCAAGCTGCAG GTGCTCCGGGAGGCCCGCGAGAGCCTGCTGGAGGACGTGCAGGCCAACACCGTGCTGGGGGCCGAGGTG GAGGCCATCGTGAAAGGCGTCTGCAAGCCCAGCGAGTTTGACAAGTTCCGGATGTTCATTGGAGACCTG GACAAAGTGGTGAACCTCCTGCTGTCGCTGTCAGGCCGCCTGGCCCGGGTGGAGAATGCCCTCAATAAT TTGGACGACGGCGCTTCTCCCGGTGATCGGCAATCACTGCTTGAGAAGCAGAGAGTCCTGATCCAGCAG CACGAGGACGCCAAGGAGCTCAAGGAGAACCTGGACCGCCGCGAGCGCATCGTCTTTGACATTTTGGCC AACTATCTGAGCGAGGAGAGCCTCGCGGACTATGAGCACTTCGTGAAGATGAAGTCGGCCCTCATCATC GAGCAGCGGGAGCTGGAAGATAAAATCCACCTTGGTGAAGAGCAGCTGAAGTGCTTATTGGACAGCCTT CAGCCCGAAAGGGGCAAATAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001649 |
| Insert Size | 4851 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001649.3 |
| RefSeq Size | 7463 bp |
| RefSeq ORF | 4851 bp |
| Locus ID | 357 |
| UniProt ID | Q13796 |
| Protein Families | Druggable Genome |
| MW | 176.4 kDa |
| Gene Summary | This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity. It is expressed in endothelial cells and facilitates the formation of a contractile network within endothelial cells. Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis. This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222295 | SHROOM2 (Myc-DDK-tagged)-Human shroom family member 2 (SHROOM2) |
CNY 11,056.00 |
|
| RC222295L1 | Lenti-ORF clone of SHROOM2 (Myc-DDK-tagged)-Human shroom family member 2 (SHROOM2) |
CNY 13,456.00 |
|
| RC222295L2 | Lenti-ORF clone of SHROOM2 (mGFP-tagged)-Human shroom family member 2 (SHROOM2) |
CNY 18,050.00 |
|
| RC222295L3 | Lenti-ORF clone of SHROOM2 (Myc-DDK-tagged)-Human shroom family member 2 (SHROOM2) |
CNY 18,050.00 |
|
| RC222295L4 | Lenti-ORF clone of SHROOM2 (mGFP-tagged)-Human shroom family member 2 (SHROOM2) |
CNY 18,050.00 |
|
| RG222295 | SHROOM2 (tGFP-tagged) - Human shroom family member 2 (SHROOM2) |
CNY 17,770.00 |
