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IGFBP3 (NM_001013398) Human Untagged Clone
CAT＃: SC301776
IGFBP3 (untagged)-Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 1
CNY 2,400.00
CNY 6,270.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BP-53; IBP3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001013398 edited
TGGGCGCTGAGGATCAGCCGCTTCCTGCCTGGATTCCACAGCTTCGCGCCGTGTACTGTC GCCCCATCCCTGCGCGCCCAGCCTGCCAAGCAGCGTGCCCCGGTTGCAGGCGTCATGCAG CGGGCGCGACCCACGCTCTGGGCCGCTGCGCTGACTCTGCTGGTGCTGCTCCGCGGGCCG CCGGTGGCGCGGGCTGGCGCGAGCTCGGGGGGCTTGGGTCCCGTGGTGCGCTGCGAGCCG TGCGACGCGCGTGCACTGGCCCAGTGCGCGCCTCCGCCCGCCGTGTGCGCGGAGCTGGTG CGCGAGCCGGGCTGCGGCTGCTGCCTGACGTGCGCACTGAGCGAGGGCCAGCCGTGCGGC ATCTACACCGAGCGCTGTGGCTCCGGCCTTCGCTGCCAGCCGTCGCCCGACGAGGCGCGA CCGCTGCAGGCGCTGCTGGACGGCCGCGGGCTCTGCGTCAACGCTAGTGCCGTCAGCCGC CTGCGCGCCTACCTGCTGCCAGCGCCGCCAGCTCCAGGTGAGCCGCCCGCGCCAGGAAAT GCTAGTGAGTCGGAGGAAGACCGCAGCGCCGGCAGTGTGGAGAGCCCGTCCGTCTCCAGC ACGCACCGGGTGTCTGATCCCAAGTTCCACCCCCTCCATTCAAAGATAATCATCATCAAG AAAGGGCATGCTAAAGACAGCCAGCGCTACAAAGTTGACTACGAGTCTCAGAGCACAGAT ACCCAGAACTTCTCCTCCGAGTCCAAGCGGGAGACAGAATATGGTCCCTGCCGTAGAGAA ATGGAAGACACACTGAATCACCTGAAGTTCCTCAATGTGCTGAGTCCCAGGGGTGTACAC ATTCCCAACTGTGACAAGAAGGGATTTTATAAGAAAAAGCAGTGTCGCCCTTCCAAAGGC AGGAAGCGGGGCTTCTGCTGGTGTGTGGATAAGTATGGGCAGCCTCTCCCAGGCTACACC ACCAAGGGGAAGGAGGACGTGCACTGCTACAGCATGCAGAGCAAGTAGACGCCTGCCGCA AGGTTAATGTGGAGCTCAAATATGCCTTATTTTGCACAAAAGACTGCCAAGGACATGACC AGCAGCTGGCTACAGCCTCGATTTATATTTCTGTTTGTGGTGAACTGATTTTTTTTAAAC CAAAGTTTAGAAAGAGGTTTTTGAAATGCCTATGGTTTCTTTGAATGGTAAACTTGAGCA TCTTTTCACTTTCCAGTAGTCAGCAAAGAGCAGTTTGAATTTTCTTGTCGCTTCCTATCA AAATATTCAGAGACTCGAGCACAGCACCCAGACTTCATGCGCCCGTGGAATGCTCACCAC ATGTTGGTCGAAGCGGCCGACCACTGACTTTGTGACTTAGGCGGCTGTGTTGCCTATGTA GAGAACACGCTTCACCCCCACTCCCCGTACAGTGCGCACAGGCTTTATCGAGAATAGGAA AACCTTTAAACCCCGGTCATCCGGACATCCCAACGCATGCTCCTGGAGCTCACAGCCTTC TGTGGTGTCATTTCTGAAACAAGGGCGTGGATCCCTCAACCAAGAAGAATGTTTATGTCT TCAAGTGACCTGTACTGCTTGGGGACTATTGGAGAAAATAAGGTGGAGTCCTACTTGTTT AAAAAATATGTATCTAAGAATGTTCTAGGGCACTCTGGGAACCTATAAAGGCAGGTATTT CGGGCCCTCCTCTTCAGGAATCTTCCTGAAGACATGGCCCAGTCGAAGGCCCAGGATGGC TTTTGCTGCGGCCCCGTGGGGTAGGAGGGACAGAGAGACAGGGAGAGTCAGCCTCCACAT TCAGAGGCATCACAAGTAATGGCACAATTCTTCGGATGACTGCAGAAAATAGTGTTTTGT AGTTCAACAACTCAAGACGAAGCTTATTTCTGAGGATAAGCTCTTTAAAGGCAAAGCTTT ATTTTCATCTCTCATCTTTTGTCCTCCTTAGCACAATGTAAAAAAGAATAGTAATATCAG AACAGGAAGGAGGAATGGCTTGCTGGGGAGCCCATCCAGGACACTGGGAGCACATAGAG: ATTCACCCATGTTTGTTGAACTTAGAGTCATTCTCATGCTTTTCTTTATAATTCACACAT ATATGCAGAGAAGATATGTTCTTGTTAACA:TTGTATACAACATAGCCCCAAATATAGTA AGATCTATACTAGATAATCCTAGATGAAATGTTAGAGATGCTATATGATACAACTGTGGC CATGACTGAGGAAAGGAGCTCACGCCCAGAGACTGGGCTGCTCTCCCGGAGGCCAAACCC AAGAAGGTCTGGCAAAGTCAGGCTCAGGGAGACTCTGCCCTGCTGCAGACCTCGGTGTGG ACACACGCTGCATAGAGCTCTCCTTGAAAACAGAGGGGTCTCAAGACATTCTGCCTACCT ATTAGCTTTTCTTTATTTTTTTAACTTTTTGGGGGGAAAAGTATTTTTGAGAAGTTTGTC TTGCAATGTATTTATAAATAGTAAATAAAGTTTTTACCATTAAAAAAATATCTTTCCCTT TGTTATTGACCATCTCTGGGCTTTGTATCACTAATTATTTTATTTTATTATATAATAATT ATTTTATTATAATAAAATCCTGAAAGGGGAAAATAAAAAAAA >OriGene 5' read for NM_001013398 unedited
NNAAGTTCACATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGTGGGCG CTGAGGATCAGCCGCTTCCTGCCTGGATTCCACAGCTTCGCGCCGTGTACTGTCGCCCCA TCCCTGCGCGCCCAGCCTGCCAAGCAGCGTGCCCCGGTTGCAGGCGTCATGCAGCGGGCG CGACCCACGCTCTGGGCCGCTGCGCTGACTCTGCTGGTGCTGCTCCGCGGGCCGCCGGTG GCGCGGGCTGGCGCGAGCTCGGGGGGCTTGGGTCCCGTGGTGCGCTGCGAGCCGTGCGAC GCGCGTGCACTGGCCCAGTGCGCGCCTCCGCCCGCCGTGTGCGCGGAGCTGGTGCGCGAG CCGGGCTGCGGCTGCTGCCTGACGTGCGCACTGAGCGAGGGCCAGCCGTGCGGCATCTAC ACCGAGCGCTGTGGCTCCGGCCTTCGCTGCCAGCCGTCGCCCGACGAGGCGCGACCGCTG CAGGCGCTGCTGGACGGCCGCGGGCTCTGCGTCAACGCTAGTGCCGTCAGCCGCCTGCGC GCCTACCTGCTGCCAGCGCCGCCAGCTCCAGGTGAGCCGCCCGCGCCAGGAAATGCTAGT GAGTCGGAGGAAGACCGCAGCGCCGGCAGTGTGGAGAGCCCGTCCGTCTCCAGCACGCAC CGGGTGTCTGATCCCAAGTTCCACCCCCTCCATTCAAAGATAATCATCATCAAGAAAGGG CATGCTAAAGACAGCCAGCGCTACAAAGTTGACTACGAGTCTCAGAGCACAGATACCCAG AACTTCTCCTCCGAGTCCAAGCGGGAGACAGAATATGGTCCCCTGCGTAGAGAAATGGAA GAACACTGAATCACCTGAAGTTCCTCATGTGCTGAGTCCCAGGGTGTACACATTCCCAAC TGTGACAAAAAGG >Forward primer walk for NM_001013398 unedited
AAACTTTANTNTTTCCGCAGCGCCGGCGTGTGGNAAGCCCGTCCGTCTCCAGCACGCACC GGGTGTCTGATCCCAAGTTCCACCCCCTCCATTCAAAGATAATCATCATCAAGAAAGGGC ATGCTAAAGACAGCCAGCGCTACAAAGTTGACTACGAGTCTCAGAGCACAGATACCCAGA ACTTCTCCTCCGAGTCCAAGCGGGAGACAGAATATGGTCCCTGCCGTAGAGAAATGGAAG ACACACTGAATCACCTGAAGTTCCTCAATGTGCTGAGTCCCAGGGGTGTACACATTCCCA ACTGTGACAAGAAGGGATTTTATAAGAAAAAGCAGTGTCGCCCTTCCAAAGGCAGGAAGC GGGGCTTCTGCTGGTGTGTGGATAAGTATGGGCAGCCTCTCCCAGGCTACACCACCAAGG GGAAGGAGGACGTGCACTGCTACAGCATGCAGAGCAAGTAGACGCCTGCCGCAAGGTTAA TGTGGAGCTCAAATATGCCTTATTTTGCACAAAAGACTGCCAAGGACATGACCAGCAGCT GGCTACAGCCTCGATTTATATTTCTGTTTGTGGTGAACTGATTTTTTTTAAACCAAAGTT TAGAAAGAGGTTTTTGAAATGCCTATGGTTTCTTTGAATGGTAAACTTGAGCATCTTTTC ACTTTCCAGTAGTCAGCAAAGAGCAGTTTGAATTTTCTTGTCGCTTCCTATCAAAATATT CAGAGACTCGAGCACAGCACCCAGACTTCATGCGCCCGTGGAATGCTCACCACATGTTGG GTCGAAGCGGCCGACCACTGGACTTGTGACTTTAGCGGCTGTGNTGCCTATGTAGAAACA CGCTTCACCCCCACTCCCGTACGTGCGCACAGGGCTTATCGAAATAGGAAACCTTAAACC CCGTCATCCGGACTCN |
| Restriction Sites | Please inquire |
| ACCN | NM_001013398 |
| Insert Size | 2600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | There is 1 nucleotide difference between the OriGene clone and the NCBI reference ORF. These result in the substitution of 1 aa and insertion of 1 aa. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001013398.1, NP_001013416.1 |
| RefSeq Size | 2638 bp |
| RefSeq ORF | 894 bp |
| Locus ID | 3486 |
| UniProt ID | P17936 |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | p53 signaling pathway |
| Gene Summary | This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Functional Modulation of IGF-Binding Protein-3 Expression in Melanoma
,Altaf A Dar, Shahana Majid, Mehdi Nosrati, David de Semir, Scot Federman, Mohammed Kashani-Sabet,
Journal of Investigative Dermatology (1 April 2010) doi:10.1038/jid.2010.70 Original Article
[IGFBP3]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216898 | IGFBP3 (Myc-DDK-tagged)-Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 1 |
CNY 2,400.00 |
|
| RC216898L1 | Lenti ORF clone of Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC216898L2 | Lenti ORF clone of Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC216898L3 | Lenti ORF clone of Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC216898L4 | Lenti ORF clone of Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
| RG216898 | IGFBP3 (tGFP-tagged) - Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 1 |
CNY 4,000.00 |
