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Uromucoid (UMOD) (NM_001008389) Human Untagged Clone
CAT＃: SC301282
UMOD (untagged)-Human uromodulin (UMOD), transcript variant 2
CNY 10,260.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADMCKD2; ADTKD1; FJHN; HNFJ; HNFJ1; MCKD2; THGP; THP |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC301282 representing NM_001008389.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGGGCAGCCATCTCTGACTTGGATGCTGATGGTGGTGGTGGCCTCTTGGTTCATCACAACTGCAGCC ACTGACACCTCAGAAGCAAGATGGTGCTCTGAATGTCACAGCAATGCCACCTGCACGGAGGATGAGGCC GTTACGACGTGCACCTGTCAGGAGGGCTTCACCGGCGATGGCCTGACCTGCGTGGACCTGGATGAGTGC GCCATTCCTGGAGCTCACAACTGCTCCGCCAACAGCAGCTGCGTAAACACGCCAGGCTCCTTCTCCTGC GTCTGCCCCGAAGGCTTCCGCCTGTCGCCCGGTCTCGGCTGCACAGACGTGGATGAGTGCGCTGAGCCT GGGCTTAGCCACTGCCACGCCCTGGCCACATGTGTCAATGTGGTGGGCAGCTACTTGTGCGTATGCCCC GCGGGCTACCGGGGGGATGGATGGCACTGTGAGTGCTCCCCGGGCTCCTGCGGGCCGGGGTTGGACTGC GTGCCCGAGGGCGACGCGCTCGTGTGCGCGGATCCGTGCCAGGCGCACCGCACCCTGGACGAGTACTGG CGCAGCACCGAGTACGGGGAGGGCTACGCCTGCGACACGGACCTGCGCGGCTGGTACCGCTTCGTGGGC CAGGGCGGTGCGCGCATGGCCGAGACCTGCGTGCCAGTCCTGCGCTGCAACACGGCCGCCCCCATGTGG CTCAATGGCACGCATCCGTCCAGCGACGAGGGCATCGTGAGCCGCAAGGCCTGCGCGCACTGGAGCGGC CACTGCTGCCTGTGGGATGCGTCCGTCCAGGTGAAGGCCTGTGCCGGCGGCTACTACGTCTACAACCTG ACAGCGCCCCCCGAGTGTCACCTGGCGTACTGCACAGACCCCAGCTCCGTGGAGGGGACGTGTGAGGAG TGCAGTATAGACGAGGACTGCAAATCGAATAATGGCAGATGGCACTGCCAGTGCAAACAGGACTTCAAC ATCACTGATATCTCCCTCCTGGAGCACAGGCTGGAATGTGGGGCCAATGACATGAAGGTGTCGCTGGGC AAGTGCCAGCTGAAGAGTCTGGGCTTCGACAAGGTCTTCATGTACCTGAGTGACAGCCGGTGCTCGGGC TTCAATGACAGAGACAACCGGGACTGGGTGTCTGTAGTGACCCCAGCCCGGGATGGCCCCTGTGGGACA GTGTTGACGAGGAATGAAACCCATGCCACTTACAGCAACACCCTCTACCTGGCAGATGAGATCATCATC CGTGACCTCAACATCAAAATCAACTTTGCATGCTCCTACCCCCTGGACATGAAAGTCAGCCTGAAGACC GCCCTACAGCCAATGGTCAGTGCTCTAAACATCAGAGTGGGCGGGACCGGCATGTTCACCGTGCGGATG GCGCTCTTCCAGACCCCTTCCTACACGCAGCCCTACCAAGGCTCCTCCGTGACACTGTCCACTGAGGCT TTTCTCTACGTGGGCACCATGTTGGATGGGGGCGACCTGTCCCGATTTGCACTGCTCATGACCAACTGC TATGCCACACCCAGTAGCAATGCCACGGACCCCCTGAAGTACTTCATCATCCAGGACAGATGCCCACAC ACTAGAGACTCAACTATCCAAGTGGTGGAGAATGGGGAGTCCTCCCAGGGCCGATTTTCCGTCCAGATG TTCCGGTTTGCTGGAAACTATGACCTAGTCTACCTGCACTGTGAAGTCTATCTCTGTGACACCATGAAT GAAAAGTGCAAGCCTACCTGCTCTGGGACCAGATTCCGAAGTGGGAGTGTCATAGATCAATCCCGTGTC CTGAACTTGGGTCCCATCACACGGAAAGGTGTCCAGGCCACAGTCTCAAGGGCTTTTAGCAGCTTGGGG CTCCTGAAAGTCTGGCTGCCTCTGCTTCTCTCGGCCACCTTGACCCTGACTTTTCAGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001008389 |
| Insert Size | 1923 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001008389.2 |
| RefSeq Size | 2427 bp |
| RefSeq ORF | 1923 bp |
| Locus ID | 7369 |
| UniProt ID | P07911 |
| MW | 69.8 kDa |
| Gene Summary | The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (a). |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224496 | UMOD (Myc-DDK-tagged)-Human uromodulin (UMOD), transcript variant 2 |
CNY 4,768.00 |
|
| RC224496L3 | Lenti-ORF clone of UMOD (Myc-DDK-tagged)-Human uromodulin (UMOD), transcript variant 2 |
CNY 5,890.00 |
|
| RC224496L4 | Lenti-ORF clone of UMOD (mGFP-tagged)-Human uromodulin (UMOD), transcript variant 2 |
CNY 5,890.00 |
|
| RG224496 | UMOD (tGFP-tagged) - Human uromodulin (UMOD), transcript variant 2 |
CNY 4,370.00 |
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