United States
Germany
Japan
United Kingdom
China
TrkB (NTRK2) (NM_001007097) Human Untagged Clone
CAT＃: SC301152
NTRK2 (untagged)-Human neurotrophic tyrosine kinase, receptor, type 2 (NTRK2), transcript variant b
CNY 3,656.00
CNY 7,220.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DEE58; EIEE58; GP145-TrkB; OBHD; trk-B; TRKB |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_001007097 edited
ATGTCGTCCTGGATAAGGTGGCATGGACCCGCCATGGCGCGGCTCTGGGGCTTCTGCTGG CTGGTTGTGGGCTTCTGGAGGGCCGCTTTCGCCTGTCCCACGTCCTGCAAATGCAGTGCC TCTCGGATCTGGTGCAGCGACCCTTCTCCTGGCATCGTGGCATTTCCGAGATTGGAGCCT AACAGTGTAGATCCTGAGAACATCACCGAAATTTTCATCGCAAACCAGAAAAGGTTAGAA ATCATCAACGAAGATGATGTTGAAGCTTATGTGGGACTGAGAAATCTGACAATTGTGGAT TCTGGATTAAAATTTGTGGCTCATAAAGCATTTCTGAAAAACAGCAACCTGCAGCACATC AATTTTACCCGAAACAAACTGACGAGTTTGTCTAGGAAACATTTCCGTCACCTTGACTTG TCTGAACTGATCCTGGTGGGCAATCCATTTACATGCTCCTGTGACATTATGTGGATCAAG ACTCTCCAAGAGGCTAAATCCAGTCCAGACACTCAGGATTTGTACTGCCTGAATGAAAGC AGCAAGAATATTCCCCTGGCAAACCTGCAGATACCCAATTGTGGTTTGCCATCTGCAAAT CTGGCCGCACCTAACCTCACTGTGGAGGAAGGAAAGTCTATCACATTATCCTGTAGTGTG GCAGGTGATCCGGTTCCTAATATGTATTGGGATGTTGGTAACCTGGTTTCCAAACATATG AATGAAACAAGCCACACACAGGGCTCCTTAAGGATAACTAACATTTCATCCGATGACAGT GGGAAGCAGATCTCTTGTGTGGCGGAAAATCTTGTAGGAGAAGATCAAGATTCTGTCAAC CTCACTGTGCATTTTGCACCAACTATCACATTTCTCGAATCTCCAACCTCAGACCACCAC TGGTGCATTCCATTCACTGTGAAAGGCAACCCCAAACCAGCGCTTCAGTGGTTCTATAAC GGGGCAATATTGAATGAGTCCAAATACATCTGTACTAAAATACATGTTACCAATCACACG GAGTACCACGGCTGCCTCCAGCTGGATAATCCCACTCACATGAACAATGGGGACTACACT CTAATAGCCAAGAATGAGTATGGGAAGGATGAGAAACAGATTTCTGCTCACTTCATGGGC TGGCCTGGAATTGACGATGGTGCAAACCCAAATTATCCTGATGTAATTTATGAAGATTAT GGAACTGCAGCGAATGACATCGGGGACACCACGAACAGAAGTAATGAAATCCCTTCCACA GACGTCACTGATAAAACCGGTCGGGAACATCTCTCGGTCTATGCTGTGGTGGTGATTGCG TCTGTGGTGGGATTTTGCCTTTTGGTAATGCTGTTTCTGCTTAAGTTGGCAAGACACTCC AAGTTTGGCATGAAAGGTTTTGTTTTGTTTCATAAGATCCCACTGGATGGGTAGCTGAAA TAAAGGAAAAGACAGAGAAAGGGGCTGTGGTGCTTGTTGGTTGATGCTGCCATGTAAGCT GGACTCCTGGGACTGCTGTTGGCTTATCCCGGGAAGTGCTGCTTATCTGGGGTTTTCTGG TAGATGTGGGCGGTGTTTGGAGGCTGTACTATATGAAGCCTGCATATACTGTGAGCTGTG ATTGGGGAACACCAATGCAGAGGTAACTCTCAGGCAGCTAAGCAGCACCTCAAGAAAACA TGTTAAATTAATGCTTCTCTTCTTACAGTAGTTCAAATACAAAACTGAAATGAAATCCCA TTGGATTGTACTTCTCTTCTGAAAAGTGTGCTTTTTGACCCTACTGGACATTTATTGACT TAATTGCTTCTGTTTATTAAAATTGACCTGCAAAGTTAAAAAAAAATTAAAGTTGAGAAC AGGTATAAGTGCACACTGAATAGTCTAATCTACATGTAACACATATTTTAGTATGATTTT CTATACTCTAATCAGCACTGAATTCAGAGGGTTTGACTTTTTCATCTATAACACAGTGAC TAAAAGAGTTAAGGGTATATATACCATCAC >OriGene 5' read for NM_001007097 unedited
TCAGTATATTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGGCCGCGAT TGTAGAAGAGACTGTGGTGTGAATTAGGGACCGGGAGGCGTCGAACGGAGGAACGGTTCA TCTTAGAGCCTCGAGGTGCATACCGGACCCCCATTCGCATCTAACAAGGAATCTGCGCCC CAGAGAGTCCCGGGAGCGCCGCCGGTCGGTGCCCGGCGCGCCGGGCCATGCAGCGACGGC CGCCGCGGAGCTCCGAGCAGCGGTAGCGCCCCCCTGTAAAGCGGTTCGCTATGCCGGGGC CACTGTGAACCCTGCCGCCTGCCGGAACACTCTTCGCTCCGGACCAGCTCAGCCTCTGAT AAGCTGGACTCGGCACGCCCGCAACAAGCACCGAGGAGTTAAGAGAGCCGCAAGCGCAGG GAAGGCCTCCCCGCACGGGTGGGGGAAAGCGGCCGGTGCAGCGCGGGGACAGGCACTCGG GCTGGCACTGGCTGCTAGGGATGTCGTCCTGGATAAGGTGGCATGGACCCGCCATGGCGC GGCTCTGGGGCTTCTGCTGGCTGGTTGTGGGCTTCTGGAGGGCCGCTTTCGCCTGTCCCA CGTCCTGCANATGCAGTGCCTCTCGGATCTGGTGCAGCGACCCTTCTCCTGGCATCGTGG CATTTCCGAGATTGGAGCCTAACAGTGTAGATCCCTGAGAACATCACCGAATTTTCATCG CANACCAGAAAAGGTTAGAAATCATCAACGAAGATGATGTTTGAGCTTTATGTGGACTGA GAAATCTGANCATTGTGGATTCTGGATTAAAATTTGTGGGCTCATAAGCATTTCTGAAAA ACAGCAACCTGCAGCACANTCATTTTTACCCCGAACAAACTGACGAGTTTGTCTAGNAAA CATTTNCGTCACCTTGACTTTGTCTGACTGATCCCTGTGGGGCATCATTTACATGCTN >OriGene 3' read for NM_001007097 unedited
TGAACGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCTTTTTAAACGTTTT TCATTTGTTTGTTTTGTTTTGTTTTGTTTTGCTGGCTAAGGAACTTTAAGACAATCCTTA ACATTGTTTGACTCTCAGACCTAAGCTAAACATTTGGACTTTTATTGACAGTGAAGGAAA TAACCTTTTAATAATACTACCAAGTCCCAAAGTGATGGTATATATACCCTTAACTCTTTT AGTCACTGTGTTATAGATGAAAAAGTCAAACCCTCTGAATTCAGTGCTGATTACAGTATA GAAAATCATACTAAAATATGTGTTACATGTAGATTACACTATTCAGTGTGCACTTATACC TGTTCTCAACTTTAATTTTTTTTTAACTTTGCAGGTCAATTTTAATAAACAGAAGCAATT AAGTCAATAAATGTCCAGTAGGGTCAAAAAAGCACACTTTCCAGAAGAGAAGTACAATCC AATGGGATTTCATTTTCACGTTTGTATTTGAACTACTGTAACAATAAAACCATTAATTTA ACATGTTTTCTTGAGGTGCTGCTTANCTGCCTGAGAGTTACCTTTGCATTGGTGTTCCCC AATAACACCTCACAGTTTATGCACGCTTCATATAGTTCAGGCTTCAAACACCGCCCACTT TTACCATAAATACCCCATATAATCACACCTTTTCCGGGATAAATCCAACACTATCTCCAG GAGTCCAGTTTTCATGCGCACATCTACTCACCATCTCCCAAGCCCCTTTTTCCCCCCTGT TTCTTTATCTAGCCTCCCCCTCCCTGGGGATTCTTTGAACAAAAACCTAACCTTTCCTGC CAAACCTCGCACTCCTTCGGCCCCCTTCCGCCAAAACACGCCTTCCACAAAGCGCCTGTT CCCCA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001007097 |
| Insert Size | 2770 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001007097.1, NP_001007098.1 |
| RefSeq Size | 7111 bp |
| RefSeq ORF | 1434 bp |
| Locus ID | 4915 |
| UniProt ID | Q16620 |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | MAPK signaling pathway, Neurotrophin signaling pathway |
| Gene Summary | This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] Transcript Variant: This variant (b, also known as TrkB-T1) lacks several 3' exons but contains an alternate 3' terminal exon (exon 16 in PMID:11798182), and it thus differs in the 3' coding region and 3' UTR, compared to variant a. The encoded isoform (b) has a distinct C-terminus and is shorter than isoform a. The 5' UTR is incomplete due to a lack of 5'-complete transcript support for this variant, and because there is ambiguity in the 5' UTR splicing pattern. Variants b and o-w all encode the same isoform (b). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205129 | NTRK2 (Myc-DDK-tagged)-Human neurotrophic tyrosine kinase, receptor, type 2 (NTRK2), transcript variant b |
CNY 3,656.00 |
|
| RC205129L1 | Lenti ORF clone of Human neurotrophic tyrosine kinase, receptor, type 2 (NTRK2), transcript variant b, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC205129L2 | Lenti ORF clone of Human neurotrophic tyrosine kinase, receptor, type 2 (NTRK2), transcript variant b, mGFP tagged |
CNY 5,890.00 |
|
| RC205129L3 | Lenti ORF clone of Human neurotrophic tyrosine kinase, receptor, type 2 (NTRK2), transcript variant b, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205129L4 | Lenti ORF clone of Human neurotrophic tyrosine kinase, receptor, type 2 (NTRK2), transcript variant b, mGFP tagged |
CNY 6,056.00 |
|
| RG205129 | NTRK2 (tGFP-tagged) - Human neurotrophic tyrosine kinase, receptor, type 2 (NTRK2), transcript variant b |
CNY 5,256.00 |
