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HTR2B (NM_000867) Human Untagged Clone
CAT＃: SC300142
HTR2B (untagged)-Human 5-hydroxytryptamine (serotonin) receptor 2B (HTR2B)
CNY 5,488.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | 5-HT(2B); 5-HT-2B; 5-HT2B |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000867 edited
GGGGGTATTTGTTTCACTGCTTTCAACCGCCTGTGCTGGAGGCTCAGAATAAGTCAATGG GAGGAGGATTTCAGTCACAGCAGCAAGCAAGTCTAGTGAACAGATAAGATGACATGCTCA GCAAAATAACAACGAAACCAGAGGGGGAACTCTCTGGCATGCAAGTTCAAACACGACTCT ACAACTACGGCAGAAAAAGAGAGAGAGAGAAACTAAAAATATATATATATCCTATTTTTT TCACAGCTATCAGTTTCTTTCACTGAGCTTTCCTAAATTTAAGCCTCTAGAAAATAATAA ATACTTGGATATCTTACCTACAAACATGGACAGATGTGTGTATGCGCTCATTTTAGAGAA CTTGAATTTTTTTTTTTAAAGGAAGGTGTCAACTTTGGCTTTTGAGTGTTTGGCATGGTT ACAATGCCTTAAAAAAACAGATGAGCAGCTTAGCTACTAACCATGCTGACCACTGTTCGG AACGGGATTGAATCACAGAAAAACAGCAAATGGCTCTCTCTTACAGAGTGTCTGAACTTC AAAGCACAATTCCTGAGCACATTTTGCAGAGCACCTTTGTTCACGTTATCTCTTCTAACT GGTCTGGATTACAGACAGAATCAATACCAGAGGAAATGAAACAGATTGTTGAGGAACAGG GAAATAAACTGCACTGGGCAGCTCTTCTGATACTCATGGTGATAATACCCACAATTGGTG GAAATACCCTTGTTATTCTGGCTGTTTCACTGGAGAAGAAGCTGCAGTATGCTACTAATT ACTTTCTAATGTCCTTGGCGGTGGCTGATTTGCTGGTTGGATTGTTTGTGATGCCAATTG CCCTCTTGACAATAATGTTTGAGGCTATGTGGCCCCTCCCACTTGTTCTATGTCCTGCCT GGTTATTTCTTGACGTTCTCTTTTCAACCGCATCCATCATGCATCTCTGTGCCATTTCAG TGGATCGTTACATAGCCATCAAAAAGCCAATCCAGGCCAATCAATATAACTCACGGGCTA CAGCATTCATCAAGATTACAGTGGTGTGGTTAATTTCAATAGGCATTGCCATTCCAGTCC CTATTAAAGGGATAGAGACTGATGTGGACAACCCAAACAATATCACTTGTGTGCTGACAA AGGAACGTTTTGGCGATTTCATGCTCTTTGGCTCACTGGCTGCCTTCTTCACACCTCTTG CAATTATGATTGTCACCTACTTTCTCACTATCCATGCTTTACAGAAGAAGGCTTACTTAG TCAAAAACAAGCCACCTCAACGCCTAACATGGTTGACTGTGTCTACAGTTTTCCAAAGGG ATGAAACACCTTGCTCGTCACCGGAAAAGGTGGCAATGCTGGATGGTTCTCGAAAGGACA AGGCTCTGCCCAACTCAGGTGATGAAACACTTATGCGAAGAACATCCACAATTGGGAAAA AGTCAGTGCAGACCATTTCCAACGAACAGAGAGCCTCAAAGGTCCTAGGGATTGTGTTTT TCCTCTTTTTGCTTATGTGGTGTCCCTTCTTTATTACAAATATAACTTTAGTTTTATGTG ATTCCTGTAACCAAACTACTCTCCAAATGCTCCTGGAGATATTTGTGTGGATAGGCTATG TTTCCTCAGGAGTGAATCCTTTGGTCTACACCCTCTTCAATAAGACATTTCGGGATGCAT TTGGCCGATATATCACCTGCAATTACCGGGCCACAAAGTCAGTAAAAACTCTCAGAAAAC GCTCCAGTAAGATCTACTTCCGGAATCCAATGGCAGAGAACTCTAAGTTTTTCAAGAAAC ATGGAATTCGAAATGGGATTAACCCTGCCATGTACCAGAGTCCAATGAGGCTCCGAAGTT CAACCATTCAGTCTTCATCAATCATTCTACTAGATACGCTTCTCCTCACTGAAAATGAAG GTGACAAAACTGAAGAGCGAGTTAGTTATGTATAGCAGAACTGGCAGTTGTCATCAAACA TAATGATGAGTAAGATGATGAATGAGATGTAAATGTGCCAAGAATATATTATATAAAGAA TTTTATGTCATATATCAAATCATCTCTTTAACCTAAGATGTAAGTATTAAGAATATCTAA TTTTCCTAATTTGGACAAGATTATTCCATGAGGAAAATAATTTTATATAGCTACAAATGA AAACAATCCAGCACTCTGGTTAAATTTTAAGGTATTCGAATGAAATAAAGTCAAATCAAT AAATTTCAGGCCAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_000867 |
| Insert Size | 2300 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The ORF of this clone is found to be a perfect match to NM_000867.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000867.2, NP_000858.2 |
| RefSeq Size | 2260 bp |
| RefSeq ORF | 1446 bp |
| Locus ID | 3357 |
| UniProt ID | P41595 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Calcium signaling pathway, Gap junction, Neuroactive ligand-receptor interaction |
| Gene Summary | This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209364 | HTR2B (Myc-DDK-tagged)-Human 5-hydroxytryptamine (serotonin) receptor 2B (HTR2B) |
CNY 5,488.00 |
|
| RC209364L1 | Lenti ORF clone of Human 5-hydroxytryptamine (serotonin) receptor 2B (HTR2B), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC209364L2 | Lenti ORF clone of Human 5-hydroxytryptamine (serotonin) receptor 2B (HTR2B), mGFP tagged |
CNY 5,890.00 |
|
| RC209364L3 | Lenti ORF clone of Human 5-hydroxytryptamine (serotonin) receptor 2B (HTR2B), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC209364L4 | Lenti ORF clone of Human 5-hydroxytryptamine (serotonin) receptor 2B (HTR2B), mGFP tagged |
CNY 5,890.00 |
|
| RG209364 | HTR2B (tGFP-tagged) - Human 5-hydroxytryptamine (serotonin) receptor 2B (HTR2B) |
CNY 7,088.00 |
