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Thyroid Peroxidase (TPO) (NM_000547) Human Untagged Clone
CAT＃: SC300094
TPO (untagged)-Human thyroid peroxidase (TPO), transcript variant 1
CNY 6,840.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MSA; TDH2A; TPX |
| Vector | PCMV6-Neo |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_000547 edited
AAGGCAATTAAGGCGCCCATTTCAGAAGAGTTACAGCCGTGAAAATTACTCAGCAGTGCA GTTGGCTGAGAAGAGGAAAAAAGAATGAGAGCGCTGGCTGTGCTGTCTGTCACGCTGGTT ATGGCCTGCACAGAAGCCTTCTTCCCCTTCATCTCGAGAGGGAAAGAACTCCTTTGGGGA AAGCCTGAGGAGTCTCGTGTCTCTAGCGTCTTGGAGGAAAGCAAGCGCCTGGTGGACACC GCCATGTACGCCACGATGCAGAGAAACCTCAAGAAAAGAGGAATCCTTTCTGCAGCTCAG CTTCTGTCTTTTTCCAAACTTCCTGAGCCAACAAGCGGAGTGATTGCCCGAGCAGCAGAG ATAATGGAAACATCAATACAAGCGATGAAAAGAAAAGTCAACCTGAAAACTCAACAATCA CAGCATCCAACGGATGCTTTATCAGAAGATCTGCTGAGCATCATTGCAAACATGTCTGGA TGTCTCCCTTACATGCTGCCCCCAAAATGCCCAAACACTTGCCTGGCGAACAAATACAGG CCCATCACAGGAGCTTGCAACAACAGAGACCACCCCAGATGGGGCGCCTCCAACACGGCC CTGGCACGATGGCTCCCTCCAGTCTATGAGGACGGCTTCAGTCAGCCCCGAGGCTGGAAC CCCGGCTTCTTGTACAACGGGTTCCCACTGCCCCCGGTCCGGGAGGTGACAAGACATGTC ATTCAAGTTTCAAATGAGGTTGTCACAGATGATGACCGCTATTCTGACCTCCTGATGGCA TGGGGACAATACATCGACCACGACATCGCGTTCACACCACAGAGCACCAGCAAAGCTGCC TTCGGGGGAGGGGCTGACTGCCAGATGACTTGTGAGAACCAAAACCCATGTTTTCCCATA CAACTCCCGGAGGAGGCCCGGCCGGCCGCGGGCACCGCCTGTCTGCCCTTCTACCGCTCT TCGGCCGCCTGCGGCACCGGGGACCAAGGCGCGCTCTTTGGGAACCTGTCCACGGCCAAC CCGCGGCAGCAGATGAACGGGTTGACCTCGTTCCTGGACGCGTCCACCGTGTATGGCAGC TCCCCGGCCCTAGAGAGGCAGCTGCGGAACTGGACCAGTGCCGAAGGGCTGCTCCGCGTC CACGCGCGCCTCCGGGACTCCGGCCGCGCCTACCTGCCCTTCGTGCCGCCACGCGCGCCT GCGGCCTGTGCGCCCGAGCCCGGCATCCCCGGAGAGACCCGCGGGCCCTGCTTCCTGGCC GGAGACGGCCGCGCCAGCGAGGTCCCCTCCCTGACGGCACTGCACACGCTGTGGCTGCGC GAGCACAACCGCCTGGCCGCGGCGCTCAAGGCCCTCAATGCGCACTGGAGCGCGGACGCC GTGTACCAGGAGGCGCGCAAGGTCGTGGGCGCTCTGCACCAGATCATCACCCTGAGGGAT TACATCCCCAGGATCCTGGGACCCGAGGCCTTCCAGCAGTACGTGGGTCCCTATGAAGGC TATGACTCCACCGCCAACCCCACTGTGTCCAACGTGTTCTCCACAGCCGCCTTCCGCTTC GGCCATGCCACGATCCACCCGCTGGTGAGGAGGCTGGACGCCAGCTTCCAGGAGCACCCC GACCTGCCCGGGCTGTGGCTGCACCAGGCTTTCTTCAGCCCATGGACATTACTCCGTGGA GGTGGTTTGGACCCACTAATACGAGGCCTTCTTGCAAGACCAGCCAAACTGCAGGTGCAG GATCAGCTGATGAACGAGGAGCTGACGGAAAGGCTCTTTGTGCTGTCCAATTCCAGCACC TTGGATCTGGCGTCCATCAACCTGCAGAGGGGCCGGGACCACGGGCTGCCAGGTTACAAT GAGTGGAGGGAGTTCTGCGGCCTGCCTCGCCTGGAGACCCCCGCTGACCTGAGCACAGCC ATCGCCAGCAGGAGCGTGGCCGACAAGATCCTGGACTTGTACAAGCATCCTGACAACATC GATGTCTGGCTGGGAGGCTTAGCTGAAAACTTCCTCCCCAGGGCTCGGACAGGGCCCCTG TTTGCCTGTCTCATTGGGAAGCAGATGAAGGCTCTGCGGGACGGTGACTGGTTTTGGTGG GAGAACAGCCACGTCTTCACGGATGCACAGAGGCGTGAGCTGGAGAAGCACTCCCTGTCT CGGGTCATCTGTGACAACACTGGCCTCACCAGGGTGCCCATGGATGCCTTCCAAGTCGGC AAATTCCCCGAAGACTTTGAGTCTTGTGACAGCATCACTGGCATGAACCTGGAGGCCTGG AGGGAAACCTTTCCTCAAGACGACAAGTGTGGCTTCCCAGAGAGCGTGGAGAATGGGGAC TTTGTGCACTGTGAGGAGTCTGGGAGGCGCGTGCTGGTGTATTCCTGCCGGCACGGGTAT GAGCTCCAAGGCCGGGAGCAGCTCACTTGCACCCAGGAAGGATGGGATTTCCAGCCTCCC CTCTGCAAAGATGTGAACGAGTGTGCAGACGGTGCCCACCCCCCCTGCCACGCCTCTGCG AGGTGCAGAAACACCAAAGGCGGCTTCCAGTGTCTCTGCGCGGACCCCTACGAGTTAGGA GACGATGGGAGAACCTGCGTAGACTCCGGGAGGCTCCCTCGGGTGACTTGGATCTCCATG TCGCTGGCTGCTCTGCTGATCGGAGGCTTCGCAGGTCTCACCTCGACGGTGATTTGCAGG TGGACACGCACTGGCACTAAATCCACACTGCCCATCTCGGAGACAGGCGGAGGAACTCCC GAGCTGAGATGCGGAAAGCACCAGGCCGTAGGGACCTCACCGCAGCGGGCCGCAGCTCAG GACTCGGAGCAGGAGAGTGCTGGGATGGAAGGCCGGGATACTCACAGGCTGCCGAGAGCC CTCTGAGGGCAAAGTGGCAGGACACTGCAGAACAGCTTCATGTTCCCAAAATCACCGTAC GACTCTTTTCCAAACACAGGCAAATCGGAAATCAGCAGGACGACTGTTTTCCCAACACGG GTAAATCTAGTACCATGTCGTAGTTACTCTCAGGCATGGATGAATAAATGTTATAGCTGT AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_000547 |
| Insert Size | 3100 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to contain one SNP compared with NM_000547.3. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000547.3, NP_000538.3 |
| RefSeq Size | 3135 bp |
| RefSeq ORF | 2802 bp |
| Locus ID | 7173 |
| UniProt ID | P07202 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Metabolic pathways, Tyrosine metabolism |
| Gene Summary | This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a, also known as TPO1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210659 | TPO (Myc-DDK-tagged)-Human thyroid peroxidase (TPO), transcript variant 1 |
CNY 6,832.00 |
|
| RC210659L1 | Lenti ORF clone of Human thyroid peroxidase (TPO), transcript variant 1, Myc-DDK-tagged |
CNY 9,232.00 |
|
| RC210659L2 | Lenti ORF clone of Human thyroid peroxidase (TPO), transcript variant 1, mGFP tagged |
CNY 9,030.00 |
|
| RC210659L3 | Lenti ORF clone of Human thyroid peroxidase (TPO), transcript variant 1, Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC210659L4 | Lenti ORF clone of Human thyroid peroxidase (TPO), transcript variant 1, mGFP tagged |
CNY 9,030.00 |
|
| RG210659 | TPO (tGFP-tagged) - Human thyroid peroxidase (TPO), transcript variant 1 |
CNY 7,890.00 |
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