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beta 1 Spectrin (SPTB) (NM_000347) Human Untagged Clone
CAT＃: SC300052
SPTB (untagged)-Human spectrin, beta, erythrocytic (SPTB), transcript variant 2
CNY 26,790.00
货期*
12周
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EL3; HS2; HSPTB1; SPH2 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_000347, the custom clone sequence may differ by one or more nucleotides
ATGACATCGGCCACAGAGTTTGAAAATGTGGGCAACCAGCCACCTTACAGCAGGATCAAT GCCCGCTGGGACGCCCCAGACGACGAGCTGGATAATGACAACAGCTCAGCCAGGCTCTTT GAGAGGTCCCGGATAAAGGCCTTGGCAGATGAGCGGGAAGTTGTTCAGAAAAAGACCTTC ACGAAATGGGTGAACTCGCACCTGGCTCGAGTGTCCTGCCGCATCACCGATCTCTACAAG GACCTGCGGGATGGGCGCATGCTCATCAAGCTGCTGGAGGTGCTCTCTGGAGAGATGCTG CCAAAGCCCACCAAGGGGAAGATGCGCATCCACTGCCTGGAGAATGTGGACAAGGCTCTC CAGTTCCTCAAGGAGCAGCGTGTACACCTGGAGAACATGGGCTCCCACGACATTGTAGAT GGCAACCACCGCCTGGTCCTGGGCCTCATCTGGACCATCATCCTCCGCTTCCAGATTCAG GACATTGTGGTCCAAACTCAGGAAGGTCGTGAAACACGCTCAGCCAAGGATGCGTTGCTG TTGTGGTGTCAGATGAAGACGGCAGGCTACCCTCATGTTAATGTCACCAACTTTACCTCC AGCTGGAAGGATGGCTTGGCCTTTAATGCCCTGATACACAAGCACCGGCCCGACCTGATC GACTTTGATAAGCTGAAGGACTCCAATGCCCGGCACAACCTGGAGCACGCATTCAATGTG GCTGAGCGCCAGCTGGGCATCATCCCGCTCCTCGACCCCGAAGATGTCTTTACGGAAAAC CCTGATGAGAAATCCATCATCACCTATGTGGTGGCCTTTTACCACTACTTCTCCAAGATG AAGGTGCTGGCAGTGGAGGGCAAGCGTGTCGGCAAGGTTATTGACCATGCCATTGAGACT GAGAAGATGATTGAAAAGTACAGCGGGCTAGCCTCGGACCTGCTCACCTGGATCGAGCAG ACCATCACTGTCCTGAACAGCCGCAAGTTTGCCAACTCGCTGACGGGCGTCCAGCAGCAG CTGCAGGCCTTCAGCACCTACCGCACCGTGGAGAAGCCGCCCAAGTTTCAAGAGAAGGGG AATCTGGAAGTTCTACTTTTTACCATCCAGTCCCGGATGAGAGCCAACAATCAGAAAGTG TACACACCCCACGATGGGAAACTAGTGTCTGACATCAACAGGGCCTGGGAAAGCCTGGAG GAAGCTGAGTATCGGCGGGAGCTGGCCCTGAGAAATGAGCTCATTCGGCAGGAGAAGCTA GAGCAACTGGCCCGGCGCTTTGACCGGAAGGCCGCAATGAGAGAGACCTGGCTCAGTGAA AACCAGCGCCTCGTGGCCCAGGATAACTTTGGGTATGACCTGGCAGCTGTGGAGGCCGCC AAGAAGAAGCATGAGGCCATCGAGACCGACACGGCTGCCTACGAGGAGCGGGTGAGAGCC CTGGAGGACCTGGCTCAGGAGCTGGAGAAAGAGAACTACCATGACCAGAAGCGCATCACG GCCCGCAAGGACAATATACTGCGCCTATGGAGCTACCTGCAGGAGCTGCTGCAGTCCCGG CGCCAGAGGCTCGAGACCACCCTGGCACTGCAGAAGCTCTTCCAGGACATGCTGCACAGC ATCGACTGGATGGATGAGATCAAGGCTCACCTCTTGTCTGCCGAGTTTGGGAAGCACTTG TTGGAGGTTGAAGACCTGCTACAGAAGCACAAGTTGATGGAAGCTGACATCGCCATCCAA GGGGACAAAGTGAAGGCCATCACCGCAGCCACCCTGAAGTTCACCGAGGGGAAAGGGTAC CAGCCTTGTGACCCCCAGGTCATCCAGGACCGCATCAGCCACTTGGAGCAGTGCTTTGAG GAGCTGAGCAACATGGCAGCTGGGCGGAAGGCCCAACTGGAGCAGTCCAAACGACTCTGG AAGTTCTTCTGGGAGATGGATGAGGCTGAGAGCTGGATCAAGGAGAAGGAGCAGATCTAT TCTTCCCTGGACTATGGCAAAGACCTGACCAGTGTGCTCATCTTACAGCGCAAGCACAAG GCCTTTGAGGATGAGCTCCGTGGGCTGGATGCTCACCTGGAGCAGATCTTCCAGGAGGCT CATGGCATGGTTGCGCGCAAGCAGTTTGGGCACCCGCAGATCGAGGCCCGCATAAAGGAG GTGTCGGCACAGTGGGACCAGCTGAAGGACCTGGCTGCCTTCTGCAAGAAGAACCTCCAG GATGCTGAGAACTTTTTCCAGTTCCAGGGCGATGCGGATGACCTGAAGGCTTGGCTGCAA GACGCCCACCGGCTGCTCTCTGGTGAAGATGTGGGGCAGGACGAAGGGGCCACGCGGGCC CTGGGGAAAAAGCACAAGGACTTCCTGGAGGAGCTGGAGGAGAGCCGTGGGGTGATGGAG CACCTGGAGCAGCAGGCCCAGGGATTCCCCGAAGAGTTTCGGGATTCCCCAGATGTGACC CATCGGCTGCAGGCCCTGCGGGAGCTCTACCAACAGGTGGTGGCCCAGGCGGACCTGCGT CAGCAGAGGCTGCAGGAAGCCCTGGACCTGTACACGGTGTTCGGGGAGACAGACGCCTGT GAGCTGTGGATGGGAGAGAAGGAGAAGTGGCTGGCCGAGATGGAAATGCCAGACACCCTG GAGGACCTGGAGGTCGTGCAGCACAGGTTCGACATCCTGGACCAGGAGATGAAGACCTTG ATGACTCAGATTGATGGTGTGAACCTCGCTGCCAACAGCTTGGTAGAGAGTGGCCACCCA CGCAGCAGGGAGGTGAAGCAGTACCAGGACCATCTGAACACCAGGTGGCAGGCATTTCAG ACCCTGGTGTCGGAGCGGCGGGAGGCTGTGGACTCAGCCCTCCGAGTGCACAACTACTGC GTAGATTGCGAGGAGACCAGCAAGTGGATCACGGACAAGACAAAGGTAGTGGAGTCCACA AAAGACCTGGGGCGGGACCTGGCAGGTATCATCGCCATCCAGAGGAAGTTGTCAGGGCTG GAGCGTGACGTGGCCGCCATCCAGGCCCGTGTGGATGCCCTGGAGCGTGAGTCCCAGCAG CTGATGGACTCGCACCCTGAGCAGAAGGAGGATATTGGTCAGCGGCAAAAACACTTGGAG GAGCTGTGGCAGGGCCTGCAGCAATCCCTGCAGGGCCAGGAGGACTTGCTGGGGGAAGTC AGCCAGCTGCAGGCCTTCCTGCAGGATCTGGATGACTTCCAGGCCTGGCTCTCCATCACC CAGAAGGCTGTGGCCTCTGAGGACATGCCCGAATCCCTCCCAGAGGCTGAGCAGCTCCTG CAGCAGCATGCAGGTATCAAGGATGAGATTGACGGGCACCAAGACAGCTACCAGCGTGTT AAGGAGTCTGGGGAGAAAGTGATCCAAGGCCAGACGGACCCAGAGTATCTGCTTCTGGGC CAGCGGCTGGAGGGCCTGGATACTGGCTGGAATGCCCTGGGCAGGATGTGGGAGAGCCGC AGCCACACCCTCGCTCAGTGCCTTGGCTTCCAGGAGTTCCAGAAAGATGCCAAGCAGGCT GAAGCCATCCTCAGCAACCAGGAATACACTCTGGCTCACTTGGAGCCCCCAGACTCCCTG GAAGCTGCAGAGGCTGGGATCCGGAAGTTTGAGGATTTCTTGGGGTCTATGGAGAACAAC CGGGATAAGGTCTTGAGTCCTGTGGACTCTGGAAACAAGCTGGTAGCTGAGGGAAACCTA TACTCAGACAAGATCAAGGAGAAGGTGCAGCTGATTGAGGACAGGCACAGGAAGAACAAC GAGAAGGCCCAGGAGGCCTCTGTCCTACTGAGAGACAACCTGGAGCTACAGAACTTCCTC CAGAACTGCCAGGAGCTCACTCTCTGGATCAACGACAAGCTGCTGACATCTCAGGATGTC TCCTATGATGAAGCACGAAACCTTCACAATAAATGGCTAAAGCACCAGGCGTTTGTGGCA GAGCTGGCTTCCCATGAAGGGTGGCTAGAGAACATCGATGCGGAAGGAAAGCAGCTGATG GATGAGAAGCCCCAGTTTACAGCCCTGGTGTCCCAAAAGCTGGAAGCCCTGCACCGGCTC TGGGACGAGCTGCAGGCCACCACAAAGGAGAAGACCCAGCACCTCTCGGCTGCCAGGAGC TCCGACCTGCGCTTGCAGACCCATGCTGACCTCAACAAGTGGATCAGCGCCATGGAGGAC CAGCTGCGGTCAGACGACCCGGGCAAGGACCTGACCAGTGTCAATCGGATGTTGGCTAAG CTGAAGCGAGTGGAGGACCAAGTGAATGTGCGAAAAGAGGAGCTGGGGGAGCTGTTTGCC CAGGTGCCTTCAATGGGAGAGGAGGGAGGAGATGCAGACTTGAGCATCGAGAAGCGGTTC CTGGACCTCCTGGAACCCCTAGGAAGGAGGAAGAAGCAGCTGGAATCATCCAGAGCCAAG CTGCAGATCAGCCGGGACTTAGAGGATGAGACGCTTTGGGTGGAGGAGAGGCTGCCTCTG GCCCAGTCAGCCGACTATGGCACTAATCTGCAAACTGTGCAACTGTTCATGAAGAAGAAC CAGACACTGCAGAATGAGATTCTGGGCCATACGCCGCGGGTTGAGGATGTGCTGCAGAGA GGGCAGCAGCTGGTGGAGGCGGCGGAGATCGACTGCCAGGACCTTGAGGAGCGCCTGGGG CACCTGCAGAGCTCCTGGGACAGGCTGCGGGAGGCAGCGGCCGGGAGGCTGCAGCGACTG AGGGACGCCAACGAGGCACAGCAGTACTACCTGGATGCAGACGAGGCTGAGGCCTGGATT GGCGAGCAGGAGCTCTACGTCATCTCCGATGAGATCCCCAAGGATGAAGAGGGCGCCATT GTGATGCTGAAGCGACATTTGCGGCAGCAGCGTGCGGTGGAGGACTACGGCCGGAACATC AAGCAGCTGGCCAGCCGGGCCCAGGGCCTGCTGTCTGCAGGCCACCCTGAGGGGGAACAG ATCATCAGACTTCAGGGGCAAGTGGACAAGCACTACGCAGGGCTGAAGGACGTGGCGGAA GAGCGCAAGCGCAAGCTGGAGAACATGTACCACCTGTTCCAGCTCAAGCGGGAGACCGAC GACCTGGAGCAGTGGATTTCAGAAAAGGAGCTAGTGGCCTCTTCCCCGGAAATGGGGCAA GACTTTGACCACGTGACTCTTCTGCGGGACAAGTTCCGGGACTTTGCCCGGGAGACCGGG GCGATTGGGCAGGAGCGGGTGGACAATGTGAATGCCTTCATCGAGCGACTCATCGACGCG GGCCACAGCGAGGCGGCCACCATCGCCGAGTGGAAGGACGGGCTGAACGAGATGTGGGCA GACCTCCTGGAGCTCATTGACACGCGCATGCAGCTGCTGGCCGCCTCCTATGACCTGCAC CGCTACTTCTACACGGGTGCCGAGATCCTGGGCCTCATCGACGAGAAGCACCGCGAGCTG CCCGAGGACGTGGGGCTGGACGCCAGCACGGCCGAGTCCTTCCACCGGGTGCACACAGCC TTCGAGCGGGAGCTCCACCTGCTGGGTGTCCAGGTGCAGCAGTTCCAGGACGTGGCCACC CGTCTGCAGACAGCATATGCTGGGGAGAAGGCAGAGGCCATCCAGAACAAGGAGCAGGAG GTGTCTGCCGCGTGGCAGGCGCTGCTCGATGCCTGTGCCGGGCGCCGGACCCAGCTAGTG GACACGGCGGATAAATTCCGCTTCTTCAGCATGGCCCGTGACCTCCTCTCCTGGATGGAG AGCATCATCCGGCAGATCGAGACCCAGGAGAGGCCCAGGGATGTCTCCTCTGTGGAACTG CTCATGAAGTATCACCAGGGCATCAATGCAGAGATTGAAACCCGGAGCAAGAACTTCAGT GCCTGCCTGGAGCTTGGCGAGTCCCTGCTGCAGCGGCAGCACCAGGCCTCAGAGGAGATC CGCGAGAAACTGCAGCAGGTGATGTCCAGGAGGAAAGAGATGAATGAGAAGTGGGAAGCC CGCTGGGAGCGGCTCCGCATGTTGCTGGAGGTGTGCCAGTTCTCGAGGGATGCCTCTGTG GCTGAGGCGTGGCTGATTGCCCAGGAGCCCTACCTGGCCAGCGGGGACTTTGGACACACA GTGGACAGTGTGGAGAAGCTCATCAAGAGGCATGAGGCTTTTGAGAAGTCCACGGCCAGC TGGGCAGAGCGCTTTGCTGCCCTGGAGAAGCCCACCACGCTTGAGCTGAAAGAACGCCAG ATTGCAGAGAGACCCGCAGAGGAGACTGGGCCTCAAGAGGAGGAAGGCGAGACAGCAGGG GAGGCTCCAGTTTCCCACCATGCGGCCACCGAGAGAACGTCCCCGGTCAGTCTCTGGTCT CGTTTGTCTAGTTCCTGGGAGTCACTGCAGCCAGAGCCCTCTCACCCCTACTAG |
| Restriction Sites | Please inquire |
| ACCN | NM_000347 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000347.4, NP_000338.3 |
| RefSeq Size | 6695 bp |
| RefSeq ORF | 6414 bp |
| Locus ID | 6710 |
| UniProt ID | P11277 |
| Protein Families | Druggable Genome |
| Gene Summary | This locus encodes a member of the spectrin gene family. Spectrin proteins, along with ankyrin, play a role in cell membrane organization and stability. The protein encoded by this locus functions in stability of erythrocyte membranes, and mutations in this gene have been associated with spherocytosis type 2, hereditary elliptocytosis, and neonatal hemolytic anemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009] Transcript Variant: This variant (2) differs in the 3' UTR and 3' coding region compared to variant 1. The resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a. This variant is also referred to as muscle beta spectrin. |
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