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RSPO3 (NM_032784) Human Untagged Clone
CAT＃: SC128235
RSPO3 (untagged)-Human R-spondin 3 homolog (Xenopus laevis) (RSPO3)
CNY 2,400.00
CNY 2,950.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CRISTIN1; PWTSR; THSD2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_032784 edited
ATGCACTTGCGACTGATTTCTTGGCTTTTTATCATTTTGAACTTTATGGAATACATCGGC AGCCAAAACGCCTCCCGGGGAAGGCGCCAGCGAAGAATGCATCCTAACGTTAGTCAAGGC TGCCAAGGAGGCTGTGCAACATGCTCAGATTACAATGGATGTTTGTCATGTAAGCCCAGA CTATTTTTTGCTCTGGAAAGAATTGGCATGAAGCAGATTGGAGTATGTCTCTCTTCATGT CCAAGTGGATATTATGGAACTCGATATCCATATATAAATAAGTGTACAAAATGCAAAGCT GACTGTGATACCTGTTTCAACAAAAATTTCTGCACAAAATGTAAAAGTGGATTTTACTTA CACCTTGGAAAGTGCCTTGACAATTGCCCAGAAGGGTTGGAAGCCAACAACCATACTATG GAGTGTGTCAGTATTGTGCACTGTGAGGTCAGTGAATGGAATCCTTGGAGTCCATGCACG AAGAAGGGAAAAACATGTGGCTTCAAAAGAGGGACTGAAACACGGGTCCGAGAAATAATA CAGCATCCTTCAGCAAAGGGTAACCTATGTCCCCCAACAAATGAGACAAGAAAGTGTACA GTGCAAAGGAAGAAGTGTCAGAAGGGAGAACGAGGAAAAAAAGGAAGGGAGAGGAAAAGA AAAAAACCTAATAAAGGAGAAAGTAAAGAAGCAATACCTGACAGCAAAAGTCTGGAATCC AGCAAAGAAATCCCAGAGCAACGAGAAAACAAACAGCAGCAGAAGAAGCGAAAAGTCCAA GATAAACAGAAATCGGTATCAGTCAGCACTGTACACTAG >OriGene 5' read for NM_032784 unedited
NCGGCCGCGNAATTCTGCACGAGGGGAAAGNGAAGGCAAGCATTACTGGGTTACTATGCA CTTGCGACTGATTTCTTGGCTTTTTATCATTTTGAACTTTATGGAATACATCGGCAGCCA AAACGCCTCCCGGGGAAGGCGCCAGCGAAGAATGCATCCTAACGTTAGTCAAGGCTGCCA AGGAGGCTGTGCAACATGCTCAGATTACAATGGATGTTTGTCATGTAAGCCCAGACTATT TTTTGCTCTGGAAAGAATTGGCATGAAGCAGATTGGAGTATGTCTCTCTTCATGTCCAAG TGGATATTATGGAACTCGATATCCATATATAAATAAGTGTACAAAATGCAAAGCTGACTG TGATACCTGTTTCAACAAAAATTTCTGCACAAAATGTAAAAGTGGATTTTACTTACACCT TGGAAAGTGCCTTGACAATTGCCCAGAAGGGTTGGAAGCCAACAACCATACTATGGAGTG TGTCAGTATTGTGCACTGTGAGGTCAGTGAATGGAATCCTTGGAGTCCATGCACGAAGAA GGGAAAAACATGTGGCTTCAAAAGAGGGACTGAAACACGGGTCCGAGAAATAATACAGCA TCCTTCAGCAAAGGGTAACCTATGTCCCCCAACAATGAGACACGAAAGTGTACAGTGCAA AGGAAGAAGTGTCAGAAGGGAGAACGAGGAAAAAAAGAAGGGAGAGGAAAAGATAAAACC TAATAAAGGAGGAAGTAAAGAAAGCATTCCTGACAGCAAAAGTCTGGGATCCAGCAAAGA AATCCCAGAGCACGAGAAAACAAACAGCCAGCGAAGAGCGAAAAGTTCCAGATAAAN >Forward primer walk for NM_032784 unedited
CCTNTATAAATAATGTACAAAATGCAAAGCTGACTGTGATACCTGTTTCACAAAAATTCT GCACAAAATGTAAAAGTGGATTTTACTTACACCTTGGAAAGTGCCTTGACAATTGCCCAG AAGGGTTGGAAGCCAACAACCATACTATGGAGTGTGTCAGTATTGTGCACTGTGAGGTCA GTGAATGGAATCCTTGGAGTCCATGCACGAAGAAGGGAAAAACATGTGGCTTCAAAAGAG GGACTGAAACACGGGTCCGAGAAATAATACAGCATCCTTCAGCAAAGGGTAACCTATGTC CCCCAACAAATGAGACAAGAAAGTGTACAGTGCANAGGAAGAAGTGTCAGAAGGGAGAAC GAGGAANAAAAGGAAGGGAGAGGAAAAGAAAAAAACCNTATAAAGGAGAAAGTAAAGAAG CAATACCTGACAGCAAAAGTCTGGAATCCAGCANAGAAATCCCAGAGCAACGAGAAAACA AACAGCAGCAGAAGAAGCGAAAAGTCCAAGATAAACAGAAAATCGTATCAGTCAGCACTG TACACTAGAGGGTTCCATGAGANTATTGTAGACTCATGATGCTGCTATCTCAACCAGATG CCCAGGACAAGTGCTCTAGCCCTTNAGACCCACAATGGACATGTCAGTTATTGCTCTGTC TAAACAACATTCCATGAGTGCTATTATCTTAATACAAGCATAGGTAACCACAAGAGCCCA AAGATCAAGGAGGGATACCTTCCAAAGGGGTGGCTTGGGGCCTTTCCTGCCTTTTAAAAA AACAGAATTTCTTGTCAATTTATCCAATGGGCTTTTAGATGTAACACCCAAATGTTGCCA TTTGGAAAAAAAC |
| Restriction Sites | Please inquire |
| ACCN | NM_032784 |
| Insert Size | 1900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_032784.3, NP_116173.2 |
| RefSeq Size | 2165 bp |
| RefSeq ORF | 819 bp |
| Locus ID | 84870 |
| UniProt ID | Q9BXY4 |
| Domains | tsp_1, FU |
| Protein Families | Druggable Genome, Secreted Protein |
| Gene Summary | This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
LGR5-targeted antibody-drug conjugate eradicates gastrointestinal tumors and prevents recurrence
,Gong, X;Azhdarinia, A;Ghosh, SC;Xiong, W;An, Z;Liu, Q;Carmon, KS;,
Mol. Cancer Ther.
,PubMed ID 27207778
[RSPO3]
|
|
Reconstitution of R-Spondin:LGR4:ZNRF3 Adult Stem Cell Growth Factor Signaling Complexes with Recombinant Proteins Produced in Escherichia coli
,Moad, HE;Pioszak, AA;,
Biochemistry. 2013 Oct 15;52(41):7295-304.
,PubMed ID 24050775
[RSPO3]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205016 | RSPO3 (Myc-DDK-tagged)-Human R-spondin 3 homolog (Xenopus laevis) (RSPO3) |
CNY 2,400.00 |
|
| RC205016L1 | Lenti ORF clone of Human R-spondin 3 homolog (Xenopus laevis) (RSPO3), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC205016L2 | Lenti ORF clone of Human R-spondin 3 homolog (Xenopus laevis) (RSPO3), mGFP tagged |
CNY 5,890.00 |
|
| RC205016L3 | Lenti ORF clone of Human R-spondin 3 homolog (Xenopus laevis) (RSPO3), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC205016L4 | Lenti ORF clone of Human R-spondin 3 homolog (Xenopus laevis) (RSPO3), mGFP tagged |
CNY 4,800.00 |
|
| RG205016 | RSPO3 (tGFP-tagged) - Human R-spondin 3 homolog (Xenopus laevis) (RSPO3) |
CNY 4,000.00 |
