DEP1 (PTPRJ) (NM_002843) Human Untagged Clone
CAT#: SC128010
PTPRJ (untagged)-Human protein tyrosine phosphatase, receptor type, J (PTPRJ), transcript variant 1
CNY 13,728.00
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CD148; DEP1; HPTPeta; R-PTP-ETA; SCC1 |
Vector | pCMV6-XL6 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF sequence for NM_002843 edited
GGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCATTTAGGTGACACTAT AGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAATTCGGCACGAGGCGGAGGAGG AGGCGAAGGAGACGGCAGGAGGCGGCGACGACGGTGCCCGGGCTCGGGCGCACGGCGGGG CCCGATTCGCGCGTCCGGGGCACGTTCCAGGGCGCGCGGGGCATGAAGCCGGCGGCGCGG GAGGCGCGGCTGCCTCCGCGCTCGCCCGGGCTGCGCTGGGCGCTGCCGCTGCTGCTGCTG CTGCTGCGCCTGGGCCAGATCCTGTGCGCAGGTGGCACCCCTAGTCCAATTCCTGACCCT TCAGTAGCAACTGTTGCCACAGGGGAAAATGGCATAACGCAGATCAGCAGTACAGCAGAA TCCTTTCATAAACAGAATGGAACTGGAACACCTCAGGTGGAAACAAACACCAGTGAGGAT GGTGAAAGCTCTGGAGCCAACGATAGTTTAAGAACACCTGAACAAGGATCTAATGGGACT GATGGGGCATCTCAAAAAACTCCCAGTAGCACTGGGCCCAGTCCTGTGTTTGACATTAAA GCTGTTTCCATCAGTCCAACCAATGTGATCTTAACTTGGAAAAGTAATGACACAGCTGCT TCTGAGTACAAGTATGTAGTAAAGCATAAGATGGAAAATGAGAAGACAATTACTGTTGTG CATCAACCATGGTGTAACATCACAGGCTTACGTCCAGCGACTTCATATGTATTCTCCATC ACTCCAGGAATAGGCAATGAGACTTGGGGAGATCCCAGAGTCATAAAAGTCATCACAGAG CCGATCCCAGTTTCTGATCTCCGTGTTGCCCTCACGGGTGTGAGGAAGGCTGCTCTCTCC TGGAGCAATGGCAATGGCACCGCCTCCTGCCGGGTTCTTCTTGAAAGCATTGGAAGCCAT GAGGAGTTGACTCAAGACTCAAGACTTCAGGTCAATATCTCGGGCCTGAAGCCAGGGGTT CAATACAACATCAACCCGTATCTTCTACAATCAAATAAGACAAAGGGAGACCCCTTGGGC ACAGAAGGTGGCTTGGATGCCAGCAATACAGAGAGAAGCCGGGCAGGGAGCCCCACCGCC CCTGTGCATGATGAGTCCCTCGTGGGACCTGTGGACCCATCCTCCGGCCAGCAGTCCCGA GACACGGAAGTCCTGCTTGTCGGGTTAGAGCCTGGCACCCGATACAATGCCACCGTTTAT TCCCAAGCAGCGAATGGCACAGAAGGACAGCCCCAGGCCATAGAGTTCAGGACAAATGCT ATTCAGGTTTTTGACGTCACCGCTGTGAACATCAGTGCCACAAGCCTGACCCTGATCTGG AAAGTCAGCGATAACGAGTCGTCATCTAACTATACCTACAAGATACATGTGGCGGGGGAG ACAGATTCTTCCAATCTCAACGTCAGTGAGCCTCGCGCTGTCATCCCCGGACTCCGCTCC AGCACCTTCTACAACATCACAGTGTGTCCTGTCCTAGGTGACATCGAGGGCACGCCGGGC TTCCTCCAAGTGCACACCCCCCCTGTTCCAGTTTCTGACTTCCGAGTGACAGTGGTCAGC ACGACGGAGATCGGCTTAGCATGGAGCAGCCATGATGCAGAATCATTTCAGATGCATATC ACACAGGAGGGAGCTGGCAATTCTCGGGTAGAAATAACCACCAACCAAAGTATTATCATT GGTGGCTTGTTCCCTGGAACCAAGTATTGCTTTGAAATAGTTCCAAAAGGACCAAATGGG ACTGAAGGGGCATCTCGGACAGTTTGCAATAGAACTGGTAAGCAAATAGGCTTTTCTGTT AAACCATCATGTTTCTTAAAGGAAATCAGTATAATTAATAAACATAATGTTTCCAAAAAA AAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCTGAAC AGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTGGAAGTTGC CACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATTAAGTTGCATCATTTTGTCTGACTA GGTGTCCTTCTATAATATAT >OriGene 5' read for NM_002843 unedited
ATTTCCCCCGCCCGTTGNCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAG CAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGC GAATTCGGCACGAGGCGGAGGAGGAGGCGAAGGAGACGGCAGGAGGCGGCGACGACGGTG CCCGGGCTCGGGCGCACGGCGGGGCCCGATTCGCGCGTCCGGGGCACGTTCCAGGGCGCG CGGGGCATGAAGCCGGCGGCGCGGGAGGCGCGGCTGCCTCCGCGCTCGCCCGGGCTGCGC TGGGCGCTGCCGCTGCTGCTGCTGCTGCTGCGCCTGGGCCAGATCCTGTGCGCAGGTGGC ACCCCTAGTCCAATTCCTGACCCTTCAGTAGCAACTGTTGCCACAGGGGAAAATGGCATA ACGCAGATCAGCAGTACAGCAGAATCCTTTCATAAACAGAATGGAACTGGAACACCTCAG GTGGAAACAAACACCAGTGAGGATGGTGAAAGCTCTGGAGCCAACGATAGTTTAAGAACA CCTGAACAAGGATCTAATGGGACTGATGGGGCATCTCAAAAACTCCCAGTAGCACTGGGC CCAGTCCTGTGTTTGACATTAAAGCTGTTTCCATCAGTCCAACCAATGTGATCTTAACTT GGAAAAGCAATGACACAGCTGCTTTCTGAGTACAAGTATGTTAGTAAAGCACTAAGATGG GAAATGGAGAAGACAATTACTTGTGTGGATCAACCATGGTGGAACATTACAGGCTTACCG TCAGCGACCTTATATGGATTCCCTCTTCCTTCAGGAAATAGCAATGACACCTCGGCNAGA ACCCCACAGTCATTAAAAGTCATTACCGGAGCCGATCCCAGCTTCCTGATTCTCCGGTGT GCCCTCCCCGGGTGGGAGGGAAGGTTGGCTCCCTCCTGAAGCCATGCCAAAGGGCACCCG CCTCCTGCCGGTTNTTT >OriGene 3' genomic read for NM_002843 unedited
NAAAATTTACTGTGNACCGCGGCCCGCTTTCGANGATCGAGTTTTTTTTTTTTTTTTTTA ATGCATTGACATTTTTTTATATTTGGTATTTGTAAGTCTTTAAAAAAAGTTTTCAGGCCA TTTTTTCCTTAAAAAAAAAAAAAAGCAACCAACAGCAATACTCTGTACAAGTATAACAAA CATTAGAAATATGCATCATTCCAAAATAGTTACAGGGAAAATTACAGTTTAGAGTCCACA TCAACACATCCTATTTGTATGTGCCCCCAAGGGAGAAAAAGCTACAGTATGTTAAACACA CAGCTGCTACACAGTAGTCTGAAAACCCAGGACTTAAAACTTTTGAGGCAAATCAACAAC AGTCACCAAGACTTGTTTAGCTCAATAAGTACAATCAAGCATTTCAAAAGAGAACCAGGC TTTTTCATCCCAGATGAAAAACACACGTGATGGGCTGCATAGCTGACCCCCGCCCCTCGA TCCCCAACCCCCGGGAGCCTCTGACTCAACAGAGCACAAATCCAGTGGAGTCAATTAGGC GGAAGTCTGGCTGGAGGTCACAGTATGGCTGCAGTGGGCAGACACCAAATGTCATTTCCT GCTGGTGCTGATCATCACTAGATCCAACTTTGGAGGCAAAAAGTCGTTGTTCCTGGGAGA TGCTATCAATGGCCCAAATCCCCCAAACCAGCTGGCCACCAGTCTTTGGCCCTTTCATTG ACACCCAAACCCATACCAGCTGCTTTTCTGTATGCAATTGTCAAAGACTGAACAGGGGCG CTCACACCATCCCCCCGATTCCACTGGACTCTTCCATTNNGAGCTCATGNTCCTGGGAGG GGGTGAAGCTCANAGCACCCTNCTCTTGGCTCTGACCAACCCCAGCCTGTGTGTCCTTTT ATATTAACATT |
Restriction Sites | NotI-NotI |
ACCN | NM_002843 |
Insert Size | 9000 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_002843.2, NP_002834.2 |
RefSeq Size | 5119 bp |
RefSeq ORF | 4014 bp |
Locus ID | 5795 |
UniProt ID | Q12913 |
Domains | Y_phosphatase, PTPc_motif, FN3 |
Protein Families | Druggable Genome, Phosphatase, Transmembrane |
Protein Pathways | Adherens junction |
Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC222707 | PTPRJ (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, J (PTPRJ), transcript variant 1 |
CNY 13,720.00 |
|
RC222707L1 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, J (PTPRJ), transcript variant 1, Myc-DDK-tagged |
CNY 16,120.00 |
|
RC222707L2 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, J (PTPRJ), transcript variant 1, mGFP tagged |
CNY 15,200.00 |
|
RC222707L3 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, J (PTPRJ), transcript variant 1, Myc-DDK-tagged |
CNY 16,120.00 |
|
RC222707L4 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, J (PTPRJ), transcript variant 1, mGFP tagged |
CNY 15,200.00 |
|
RG222707 | PTPRJ (tGFP-tagged) - Human protein tyrosine phosphatase, receptor type, J (PTPRJ), transcript variant 1 |
CNY 14,630.00 |