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TCPTP (PTPN2) (NM_080423) Human Untagged Clone
CAT＃: SC128001
PTPN2 (untagged)-Human protein tyrosine phosphatase, non-receptor type 2 (PTPN2), transcript variant 3
CNY 3,656.00
| Cited in 1 publication. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PTN2; PTPT; TC-PTP; TCELLPTP; TCPTP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC128001 sequence for NM_080423 edited (data generated by NextGen Sequencing)
ATGCCCACCACCATCGAGCGGGAGTTCGAAGAGTTGGATACTCAGCGTCGCTGGCAGCCG CTGTACTTGGAAATTCGAAATGAGTCCCATGACTATCCTCATAGAGTGGCCAAGTTTCCA GAAAACAGAAATCGAAACAGATACAGAGATGTAAGCCCATATGATCACAGTCGTGTTAAA CTGCAAAATGCTGAGAATGATTATATTAATGCCAGTTTAGTTGACATAGAAGAGGCACAA AGGAGTTACATCTTAACACAGGGTCCACTTCCTAACACATGCTGCCATTTCTGGCTTATG GTTTGGCAGCAGAAGACCAAAGCAGTTGTCATGCTGAACCGCATTGTGGAGAAAGAATCG GTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAGATGCTGTTTAAAGAAACAGGA TTCAGTGTGAAGCTCTTGTCAGAAGATGTGAAGTCGTATTATACAGTACATCTACTACAA TTAGAAAATATCAATAGTGGTGAAACCAGAACAATATCTCACTTTCATTATACTACCTGG CCAGATTTTGGAGTCCCTGAATCACCAGCTTCATTTCTCAATTTCTTGTTTAAAGTGAGA GAATCTGGCTCCTTGAACCCTGACCATGGGCCTGCGGTGATCCACTGTAGTGCAGGCATT GGGCGCTCTGGCACCTTCTCTCTGGTAGACACTTGTCTTGTTTTGATGGAAAAAGGAGAT GATATTAACATAAAACAAGTGTTACTGAACATGAGAAAATACCGAATGGGTCTTATTCAG ACCCCAGATCAACTGAGATTCTCATACATGGCTATAATAGAAGGAGCAAAATGTATAAAG GGAGATTCTAGTATACAGAAACGATGGAAAGAACTTTCTAAGGAAGACTTATCTCCTGCC TTTGATCATTCACCAAACAAAATAATGACTGAAAAATACAATGGGAACAGAATAGGTCTA GAAGAAGAAAAACTGACAGGTGACCGATGTACAGGACTTTCCTCTAAAATGCAAGATACA ATGGAGGAGAACAGTGAGAGGCCAAGATTGACAGACACCTAA Clone variation with respect to NM_080423.2 >OriGene 5' read for NM_080423 unedited
NTGGGGTCGCATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCCATTACGGCCGG GGGAGCGCGCATGCGCCGCAGCGCCAGCGCTCTCCCCGGATCGTGCGGGGCCTGAGCCTC TCCGCCGGCGCAGGCTCTGCTCGCGCCAGCTCGCTCCCGCAGCCATGCCCACCACCATCG AGCGGGAGTTCGAAGAGTTGGATACTCAGCGTCGCTGGCAGCCGCTGTACTTGGAAATTC GAAATGAGTCCCATGACTATCCTCATAGAGTGGCCAAGTTTCCAGAAAACAGAAATCGAA ACAGATACAGAGATGTAAGCCCATATGATCACAGTCGTGTTAAACTGCAAAATGCTGAGA ATGATTATATTAATGCCAGTTTAGTTGACATAGAAGAGGCACAAAGGAGTTACATCTTAA CACAGGGTCCACTTCCTAACACATGCTGCCATTTCTGGCTTATGGTTTGGCAGCAGAAGA CCAAAGCAGTTGTCATGCTGAACCGCATTGTGGAGAAAGAATCGGTTAAATGTGCACAGT ACTGGCCAACAGATGACCAAGAGATGCTGTTTAAAGAAACAGGATTCAGTGTGAAGCTCT TGTCAGAAGATGTGAAGTCGTATTATACAGTACATCTACTACAATTAGAAAATATCAATA GTGGTGAAACCAGAACAATATCTCACTTTCATTATACTACCTGGCCAGATTTTGGAGTCC CTGAATCACCAGCTTCATTTCTCAATTTCTTGTTTAAAGTGAGAGAATCTGGCTCCTTGA ACCCTGACCATGGGCCTGCGGTGATCCACTGTAGTGCAGGCATTGNGCGCTCTGGCACCT TCTCTCTGGTAGACACTTGGTCTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_080423 |
| Insert Size | 1600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_080423.1, NP_536348.1 |
| RefSeq Size | 1623 bp |
| RefSeq ORF | 1062 bp |
| Locus ID | 5771 |
| UniProt ID | P17706 |
| Domains | Y_phosphatase |
| Protein Families | Druggable Genome, Phosphatase, Transmembrane |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011] Transcript Variant: This variant (3) contains an alternate 3' region, which includes a part of the C-terminal coding region, when compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus, as compared to isoform 1. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Reactive oxygen species-responsive miR-210 regulates proliferation and migration of adipose-derived stem cells via PTPN2
,J H Kim, S G Park, S-Y Song, J K Kim & J-H Sung,
Cell Death and Disease 4, e588 doi:10.1038/cddis.2013.117
,PubMed ID 23579275
[PTPN2]
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| RC205090L4 | Lenti ORF clone of Human protein tyrosine phosphatase, non-receptor type 2 (PTPN2), transcript variant 3, mGFP tagged |
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| RG205090 | PTPN2 (tGFP-tagged) - Human protein tyrosine phosphatase, non-receptor type 2 (PTPN2), transcript variant 3 |
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