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GLUR3 (GRIA3) (NM_007325) Human Untagged Clone
CAT＃: SC127844
GRIA3 (untagged)-Human glutamate receptor, ionotrophic, AMPA 3 (GRIA3), transcript variant 1
CNY 9,832.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GluA3; GLUR-C; GLUR-K3; GLUR3; GLURC; MRX94; MRXSW |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127844 sequence for NM_007325 edited (data generated by NextGen Sequencing)
ATGGCCAGGCAGAAGAAAATGGGGCAAAGCGTGCTCCGGGCGGTCTTCTTTTTAGTCCTG GGGCTTTTGGGTCATTCTCACGGAGGATTCCCCAACACCATCAGCATAGGTGGACTTTTC ATGAGAAACACAGTGCAGGAGCACAGCGCTTTCCGCTTTGCCGTGCAGTTATACAACACC AACCAGAACACCACCGAGAAGCCCTTCCATTTGAATTACCACGTAGATCACTTGGATTCC TCCAATAGTTTTTCCGTGACAAATGCTTTCTGCTCCCAGTTCTCGAGAGGGGTGTATGCC ATCTTTGGATTCTATGACCAGATGTCAATGAACACCCTGACCTCCTTCTGTGGGGCCCTG CACACATCCTTTGTTACGCCTAGCTTCCCCACTGACGCAGATGTGCAGTTTGTCATCCAG ATGCGCCCAGCCTTGAAGGGCGCTATTCTGAGTCTTCTGGGTCATTACAAGTGGGAGAAG TTTGTGTACCTCTATGACACAGAACGAGGATTTTCCATCCTCCAAGCGATTATGGAAGCA GCAGTGCAAAACAACTGGCAAGTAACAGCAAGGTCTGTGGGAAACATAAAGGACGTCCAA GAATTCAGGCGCATCATTGAAGAAATGGACAGGAGGCAGGAAAAGCGATACTTGATTGAC TGCGAAGTCGAAAGGATTAACACAATTTTGGAACAGGTTGTGATCCTAGGGAAACACTCA AGAGGTTATCACTACATGCTCGCTAACCTGGGTTTTACTGATATTTTACTGGAAAGAGTC ATGCATGGGGGAGCCAACATTACAGGTTTCCAGATTGTCAACAATGAAAACCCTATGGTT CAGCAGTTCATACAGCGCTGGGTGAGGCTGGATGAAAGGGAATTCCCTGAAGCCAAGAAT GCACCACTAAAGTATACATCTGCATTGACACACGACGCAATACTGGTCATAGCAGAAGCT TTCCGCTACCTGAGGAGGCAGCGAGTAGATGTGTCCCGGAGAGGAAGTGCTGGAGACTGC TTAGCAAATCCTGCTGTGCCCTGGAGTCAAGGAATTGATATTGAGAGAGCTCTGAAAATG GTGCAAGTACAAGGAATGACTGGAAATATTCAATTTGACACTTATGGACGTAGGACAAAT TATACCATCGATGTGTATGAAATGAAAGTCAGTGGCTCTCGAAAAGCTGGCTACTGGAAT GAGTATGAAAGGTTTGTGCCTTTCTCAGATCAGCAAATCAGCAATGACAGTGCATCCTCA GAGAATCGGACCATAGTAGTGACTACCATTCTGGAATCACCATATGTAATGTACAAGAAG AACCATGAGCAACTGGAAGGAAATGAACGATATGAAGGCTATTGTGTAGACCTAGCCTAT GAAATAGCCAAACATGTAAGGATCAAATACAAATTGTCCATCGTTGGTGACGGGAAATAT GGTGCAAGGGATCCAGAGACTAAAATATGGAACGGCATGGTTGGGGAACTTGTCTATGGG AGAGCTGATATAGCTGTTGCTCCACTCACTATAACATTGGTCCGTGAAGAAGTCATAGAT TTTTCAAAGCCATTCATGAGCCTGGGCATCTCCATCATGATAAAGAAGCCTCAGAAATCA AAACCAGGCGTATTCTCATTTCTGGATCCCCTGGCTTATGAAATCTGGATGTGCATTGTC TTTGCTTACATTGGAGTCAGCGTAGTTCTTTTCCTAGTCAGCAGGTTCAGTCCTTATGAA TGGCACTTGGAAGACAACAATGAAGAACCTCGTGACCCACAAAGTCCTCCTGATCCTCCA AATGAATTTGGAATATTTAACAGTCTTTGGTTTTCCTTGGGTGCCTTTATGCAGCAAGGA TGTGATATTTCTCCAAGATCACTCTCCGGGCGCATTGTTGGAGGGGTTTGGTGGTTCTTC ACCCTGATCATAATTTCTTCCTATACTGCCAATCTCGCTGCTTTCCTGACTGTGGAGAGG ATGGTTTCTCCCATAGAGAGTGCTGAAGACTTAGCTAAACAGACTGAAATTGCATATGGG ACCCTGGACTCCGGTTCAACAAAAGAATTTTTCAGAAGATCCAAAATTGCTGTGTACGAG AAAATGTGGTCTTACATGAAATCAGCGGAGCCATCTGTGTTTACCAAAACAACAGCAGAC GGAGTGGCCCGAGTGCGAAAGTCCAAGGGAAAGTTCGCCTTCCTGCTGGAGTCAACCATG AATGAGTACATTGAGCAGAGAAAACCATGTGATACGATGAAAGTTGGTGGAAATCTGGAT TCCAAAGGCTATGGTGTGGCAACCCCTAAAGGCTCAGCATTARGAACGCCTGTAAACCTT GCAGTATTGAAACTCAGTGAACAAGGCATCTTAGACAAGCTGAAAAACAAATGGTGGTAC GATAAGGGGGAATGTGGAGCCAAGGACTCCGGGAGTAAGGACAAGACCAGCGCTCTGAGC CTGAGCAATGTGGCAGGCGTTTTCTATATACTTGTCGGAGGTCTGGGGCTGGCCATGATG GTGGCTTTGATAGAATTCTGTTACAAATCACGGGCAGAGTCCAAACGCATGAAACTCACA AAGAACACCCAAAACTTTAAGCCTGCTCCTGCCACCAACACTCAGAATTATGCTACATAC AGAGAAGGCTACAACGTGTATGGAACAGAGAGTGTTAAGATCTAG Clone variation with respect to NM_007325.4 2323 g=>r >OriGene 5' read for NM_007325 unedited
GCGAATTCGGCACGAGGCTCTTGTCAGCTTCGTTTTAGGCGTAGCATGGCCAGGCAGAAG AAAATGGGGCAAAGCGTGCTCCGGGCGGTCTTCTTTTTAGTCCTGGGGCTTTTGGGTCAT TCTCACGGAGGATTCCCCAACACCATCAGCATAGGTGGACTTTTCATGAGAAACACAGTG CAGGAGCACAGCGCTTTCCGCTTTGCCGTGCAGTTATACAACACCAACCAGAACACCACC GAGAAGCCCTTCCATTTGAATTACCACGTAGATCACTTGGATTCCTCCAATAGTTTTTCC GTGACAAATGCTTTCTGCTCCCAGTTCTCGAGAGGGGTGTATGCCATCTTTGGATTCTAT GACCAGATGTCAATGAACACCCTGACCTCCTTCTGTGGGGCCCTGCACACATCCTTTGTT ACGCCTAGCTTCCCCACTGACGCAGATGTGCAGTTTGTCATCCAGATGCGCCCAGCCTTG AAGGGCGCTATTCTGAGTCTTCTGGGTCATTACAAGTGGGAGAAGTTTGTGTACCTCTAT GACACAGAACGAGGATTTTCCATCCTCCAAGCGATTATGGAAGCAGCAGTGCANAACAAC TGGCAAGTAACAGCAGGGTCTGTGGGAAACATANAGGACGTCCAAGAATTCAGGCGCATC ATTGAAGAAATGGACAGGAGGCAGGAANAGCGATACTTGATTGACTGGGAAGTCGAAAGG ATAAACACATTTGGACAGGGTGGTGATCTAGGGAACATCCAAGAGTTATACTCA >OriGene 3' read for NM_007325 unedited
NGGGCCTGAGGTATTTCATCACTTAAGTATTAAAACTTTGTACAATACCTCATGGCAATG AGGCTCTGTAGTTTATGCCCACACATGCAAATTACGCTTTTATAGCCATTAGTTTGCTTG GCAATTTTTCTGTTCACTGAAGTACAGCTTTAACAACAAAAAGAAAAGAATTGGAAAAAA AATCCTCAAGTGACTACTGCCAAACTCCCATAGCTTGAAGTTAGTAGCAGAAATTTGAAG CAATCAACTTTTTTTTAAACATGCAAGTTTTTTTTAAAAAATAACAAACCAATTTACCCG CCTCTTCATCTCAGTGACGTTTCCTCTCTGAAAAACTGATTTGAGTTAATAAACATACAT TTTTCTTTATACAGTGCCTATGAAAACATTTGTGTGTAGGTTGGTTGGTTTGTTTTATAC AACTTCATGTTCACACAGCGTGAGCTTCCCGCGCTGGGACATTATAGCATTCATAAGTTG AAAATCACAGTTTCATGAAAACAAAACAAAACAAAAACACAACAGCTTTCTTTTTTTGTT CAATACCATTTGAAATTTGACAAGTGAGTTGTTTGCTTATGACACCATTTTTGGAATGAA AGTTTATAGTACACTTTTCTGGAAACATTTCGTTGGAACGATACTTCTTCCTTTCTTTTC TGAAGACAAGAGCAAATATGCAGCGAGTCAACTAAGCATCTAAGGGTCACACTTGGGAAA TGAATGCGAGCTCCTAGTTTTTGCAGTCTGGAAACTTCCCAATGCACGTTATCGATGAGA GCAAACTACTGAACTACAGGAAGCATACGTCGTTATATAGGAAGTAATTAGTGAGTGGAG ACTATTTCTTCGACTGTTCTGATGATGCCAACGGCAGGATGCAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_007325 |
| Insert Size | 4500 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_007325.2, NP_015564.2 |
| RefSeq Size | 3148 bp |
| RefSeq ORF | 2685 bp |
| Locus ID | 2892 |
| UniProt ID | P42263 |
| Protein Families | Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane |
| Protein Pathways | Long-term depression, Neuroactive ligand-receptor interaction |
| Gene Summary | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes isoform 1 (also known as flip isoform). RNA editing (AGA->GGA) changes Arg775Gly. |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219063 | GRIA3 (Myc-DDK-tagged)-Human glutamate receptor, ionotrophic, AMPA 3 (GRIA3), transcript variant 1 |
CNY 7,130.00 |
|
| RC219063L1 | Lenti ORF clone of Human glutamate receptor, ionotrophic, AMPA 3 (GRIA3), transcript variant 1, Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC219063L2 | Lenti ORF clone of Human glutamate receptor, ionotrophic, AMPA 3 (GRIA3), transcript variant 1, mGFP tagged |
CNY 9,030.00 |
|
| RC219063L3 | Lenti ORF clone of Human glutamate receptor, ionotrophic, AMPA 3 (GRIA3), transcript variant 1, Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC219063L4 | Lenti ORF clone of Human glutamate receptor, ionotrophic, AMPA 3 (GRIA3), transcript variant 1, mGFP tagged |
CNY 9,030.00 |
|
| RG219063 | GRIA3 (tGFP-tagged) - Human glutamate receptor, ionotrophic, AMPA 3 (GRIA3), transcript variant 1 |
CNY 7,890.00 |
