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MMP8 (NM_002424) Human Untagged Clone
CAT＃: SC127843
MMP8 (untagged)-Human matrix metallopeptidase 8 (neutrophil collagenase) (MMP8)
CNY 3,656.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CLG1; HNC; MMP-8; PMNL-CL |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127843 sequence for NM_002424 edited (data generated by NextGen Sequencing)
ATGTTCTCCCTGAAGACGCTTCCATTTCTGCTCTTACTCCATGTGCAGATTTCCAAGGCC TTTCCTGTATCTTCTAAAGAGAAAAATACAAAAACTGTTCAGGACTACCTGGAAAAGTTC TACCAATTACCAAGCAACCAGTATCAGTCTACAAGGAAGAATGGCACTAATGTGATCGTT GAAAAGCTTAAAGAAATGCAGCGATTTTTTGGGTTGAATGTGACGGGGAAGCCAAATGAG GAAACTCTGGACATGATGAAAAAGCCTCGCTGTGGAGTGCCTGACAGTGGTGGTTTTATG TTAACCCCAGGAAACCCCAAGTGGGAACGCACTAACTTGACCTACAGGATTCGAAACTAT ACCCCACAGCTGTCAGAGGCTGAGGTAGAAAGAGCTATCAAGGATGCCTTTGAACTCTGG AGTGTTGCATCACCTCTCATCTTCACCAGGATCTCACAGGGAGAGGCAGATATCAACATT GCTTTTTACCAAAGAGATCACGGTGACAATTCTCCATTTGATGGACCCAATGGAATCCTT GCTCATGCCTTTCAGCCAGGCCAAGGTATTGGAGGAGATGCTCATTTTGATGCCGAAGAA ACATGGACCAACACCTCCGCAAATTACAACTTGTTTCTTGTTGCTGCTCATGAATTTGGC CATTCTTTGGGGCTCGCTCACTCCTCTGACCCTGGTGCCTTGATGTATCCCAACTATGCT TTCAGGGAAACCAGCAACTACTCACTCCCTCAAGATGACATCGATGGCATTCAGGCCATC TATGGACTTTCAAGCAACCCTATCCAACCTACTGGACCAAGCACACCCAAACCCTGTGAC CCCAGTTTGACATTTGATGCTATCACCACACTTCGTGGAGAAATACTTTTCTTTAAAGAC AGGTACTTCTGGAGAAGGCATCCTCAGCTACAAAGAGTCGAAATGAATTTTATTTCTCTA TTCTGGCCATCCCTTCCAACTGGTATACAGGCTGCTTATGAAGATTTTGACAGAGACCTC ATTTTCCTATTTAAAGGCAACCAATACTGGGCTCTGAGTGGCTATGATATTCTGCAAGGT TATCCCAAGGATATATCAAACTATGGCTTCCCCAGCAGCGTCCAAGCAATTGACGCAGCT GTTTTCTACAGAAGTAAAACATACTTCTTTGTAAATGACCAATTCTGGAGATATGATAAC CAAAGACAATTCATGGAGCCAGGTTATCCCAAAAGCATATCAGGTGCCTTTCCAGGAATA GAGAGTAAAGTTGATGCAGTTTTCCAGCAAGAACATTTCTTCCATGTCTTCAGTGGACCA AGATATTACGCATTTGATCTTATTGCTCAGAGAGTTACCAGAGTTGCAAGAGGCAATAAA TGGCTTAACTGTAGATATGGCTGA Clone variation with respect to NM_002424.2 873 c=>t >OriGene 5' read for NM_002424 unedited
CCCCCAGGCGANACCCCNNCCCCCCCCCCCCCCCGTTCGACATTTGTNATACGACTCACT ATAGGGCGGCNCGCGATTCGGCACGAGNAACCTCAGGGTGCTCGCCAGGGAAGGGCCCTA CCCAGAGGGACAGAAAGAAAGCCAGGAGGGGTAGAGTTTGAAGAGAAGATCATGTTCTCC CTGAAGACGCTTCCATTTCTGCTCTTACTCCATGTGCAGATTTCCAAGGCCTTTCCTGTA TCTTCTAAAGAGAAAAATACAAAAACTGTTCAGGACTACCTGGAAAAGTTCTACCAATTA CCAAGCAACCAGTATCAGTCTACAAGGAAGAATGGCACTAATGTGATCGTTGAAAAGCTT AAAGAAATGCAGCGATTTTTTGGGTTGAATGTGACGGGGAAGCCAAATGAGGAAACTCTG GACATGATGAAAAAGCCTCGCTGTGGAGTGCCTGACAGTGGTGGTTTTATGTTAACCCCA GGAAACCCCAAGTGGGAACGCACTAACTTGACCTACAGGATTCGAAACTATACCCCACAG CTGTCAGAGGCTGAGGTAGAAAGAGCTATCAAGGATGCCTTTGAACTCTGGAGTGTTGCA TCACCTCTCATCTTCACCAGGATCTCACAGGGAGAGGCAGATATCAACATTGCTTTTTAC CAAAGAGATCACGGTGACAATTCTCCATTTGATGGACCCAATGGAATCCTTGCTCATGCC TTTCAGCCCAGCCAAGGTATTGGAGGAGATGCTCATTTTGATGCCCAAGAACATGGACCA ACACCTCCGCAAATACAACTTGGTTCTTGGTGCTGCTCATGAAATTGGGCCATTCTTTGG GGCTTGTTCACTCCTTTGACCCTGGTGCCTTGATGTATCCCCNCTATGGCTTTAGGGAAA ACCACAACTACCCCTCCCTAAGAAGAACTCGATGGCTTTAGGCCCTCTATGGACTTTCAA CCACCCCTT >OriGene 3' read for NM_002424 unedited
GGTCCAGGAACAGCACTGGGGCAGGGTACCAGGGTATGCCACCCGGGTATCTGGTTCAGG TAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCATTT GAAGTAAAAATCTTTAATTTGAACTTATTTAATAGATTATTTTAATTTTTGAACAAGCAT AAGGGTGCCAATTTAATTATCTGTGGGATTTAAAAACTTCAACAGAGAAAGAAAATAGGA GGTACTAGTGAGAAATATATTTCACAGTCTACATATTTATTGTATCCTAAGCTATATTAT ATTCTAATAACACCAAATATAACCTTATAATGATCTTGATATCTGGACTCGCTAGCCTAG GTCCAATAAATCCTATAGTTCTCACCACCGAAACCCATCCGTTAGCAAAATNACGCTTGT AAGCTGAGTTTAATGCAACTTAATGAGACATTGAATTTTATGCACCTAACCCAAATTCTC TATCGCCCGTGCCCCCCTGAGCCCCCCAGGAAATAGAAGTCAAAAACTGACCTCCCCTCC GCTCCAACTGGTCCTCTTCGGTTCGGGACTCTCGGCCACTAAAAGGATGACGCCCGATAG GAAATGGTGTTTTTCTTCTGACCGCTGCCCTCGCGAACTGTCTCTTTTATTTCCGCGAGA AAGGGATGACACTACAGCCCTCTAGAGACGTCTCATATAATATGCCGCCGCGGAAAAGCC CCCCCGCTCATAATGTTCTAGGGTGTTTGACAAATTTTCTTCTCTCTTTGGGGCTAAAGC CTCTCCATAAAAACACCCTCTCCCCGCCCCCGAATACCCCCGCAATTACTACTATAAAGA GAACCGCCGGGATAAAATTCTGCATTGCTTTCTCTGGGGCTTTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002424 |
| Insert Size | 3050 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002424.1, NP_002415.1 |
| RefSeq Size | 2223 bp |
| RefSeq ORF | 1404 bp |
| Locus ID | 4317 |
| UniProt ID | P22894 |
| Domains | hemopexin, Peptidase_M10, ZnMc |
| Protein Families | Druggable Genome, Protease |
| Gene Summary | This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] Transcript Variant: This variant (1) represents the shortest transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Thioredoxin fusion construct enables high-yield production of soluble, active matrix metalloproteinase-8 (MMP-8) in Escherichia Coli
,null,
Protein expression and purification
,PubMed ID 26923061
[MMP8]
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| RC210391L2 | Lenti ORF clone of Human matrix metallopeptidase 8 (neutrophil collagenase) (MMP8), mGFP tagged |
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| RC210391L3 | Lenti ORF clone of Human matrix metallopeptidase 8 (neutrophil collagenase) (MMP8), Myc-DDK-tagged |
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| RC210391L4 | Lenti ORF clone of Human matrix metallopeptidase 8 (neutrophil collagenase) (MMP8), mGFP tagged |
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| RG210391 | MMP8 (tGFP-tagged) - Human matrix metallopeptidase 8 (neutrophil collagenase) (MMP8) |
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