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MLH3 (NM_014381) Human Untagged Clone
CAT＃: SC127828
MLH3 (untagged)-Human mutL homolog 3 (E. coli) (MLH3), transcript variant 2
CNY 9,784.00
货期*
现货
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HNPCC7 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127828 sequence for NM_014381 edited (data generated by NextGen Sequencing)
ATGATCAAGTGCTTGTCAGTTGAAGTACAAGCCAAATTGCGTTCTGGTTTGGCCATAAGC TCCTTGGGCCAATGTGTTGAGGAACTTGCCCTCAACAGTATTGATGCTGAAGCAAAATGT GTGGCTGTCAGGGTGAATATGGAAACCTTCCAAGTTCAAGTGATAGACAATGGATTTGGG ATGGGGAGTGATGATGTAGAGAAAGTGGGAAATCGTTATTTCACCAGTAAATGCCACTCG GTACAGGACTTGGAGAATCCAAGGTTTTATGGTTTCCGAGGAGAGGCCTTGGCAAATATT GCTGACATGGCCAGTGCTGTGGAAATTTCGTCCAAGAAAAACAGGACAATGAAAACTTTT GTGAAACTGTTTCAGAGTGGAAAAGCCCTGAAAGCTTGTGAAGCTGATGTGACTAGAGCA AGCGCTGGGACTACTGTAACAGTGTATAACCTATTTTACCAGCTTCCTGTAAGGAGGAAA TGCATGGACCCTAGACTGGAGTTTGAGAAGGTTAGGCAGAGAATAGAAGCTCTCTCACTC ATGCACCCTTCCATTTCTTTCTCTTTGAGAAATGATGTTTCTGGTTCCATGGTTCTTCAG CTCCCTAAAACCAAAGACGTATGTTCCCGATTTTGTCAAATTTATGGATTGGGAAAGTCC CAAAAGCTAAGAGAAATAAGTTTTAAATATAAAGAGTTTGAGCTTAGTGGCTATATCAGC TCTGAAGCACATTACAACAAGAATATGCAGTTTTTGTTTGTGAACAAAAGACTAGTTTTA AGGACAAAGCTACATAAACTCATTGACTTTTTATTAAGGAAAGAAAGTATTATATGCAAG CCAAAGAATGGTCCCACCAGTAGGCAAATGAATTCAAGTCTTCGGCACCGGTCTACCCCA GAACTCTATGGCATATATGTAATTAATGTGCAGTGCCAATTCTGTGAGTATGATGTGTGC ATGGAGCCAGCCAAAACTCTGATTGAATTTCAGAACTGGGACACTCTCTTGTTTTGCATT CAGGAAGGAGTGAAAATGTTTTTAAAGCAAGAAAAATTATTTGTGGAATTATCAGGTGAG GATATTAAGGAATTTAGTGAAGATAATGGTTTTAGTTTATTTGATGCTACTCTTCAGAAG CGTGTGACTTCCGATGAGAGGAGCAATTTCCAGGAAGCATGTAATAATATTTTAGATTCC TATGAGATGTTTAATTTGCAGTCAAAAGCTGTGAAAAGAAAAACTACTGCAGAAAACGTA AACACACAGAGTTCTAGGGATTCAGAAGCTACCAGAAAAAATACAAATGATGCATTTTTG TACATTTATGAATCAGGTGGTCCAGGCCATAGCAAAATGACAGAGCCATCTTTACAAAAC AAAGACAGCTCTTGCTCAGAATCAAAGATGTTAGAACAAGAGACAATTGTAGCATCAGAA GCTGGAGAAAATGAGAAACATAAAAAATCTTTCCTGGAACATAGCTCTTTAGAAAATCCG TGTGGAACCAGTTTAGAAATGTTTTTAAGCCCTTTTCAGACACCATGTCACTTTGAGGAG AGTGGGCAGGATCTAGAAATATGGAAAGAAAGTACTACTGTTAATGGCATGGCTGCCAAC ATCTTGAAAAATAATAGAATTCAGAATCAACCAAAGAGATTTAAAGATGCTACTGAAGTG GGATGCTAGCCTCTGCCTTTTGCAACAACATTATGGGGAGTACATAGTGCTCAGACAGAG AAAGAGAAAAAAAAAGAATCTAGCAATTGTGGAAGAAGAAATGTTTTTAGTTATGGGCGA GTTAAATTATGTTCCACTGGCTTTATAACTCATGTAGTACAAAATGAAAAAACTAAATCA ACTGAAACAGAACATTCATTTAAAAATTATGTTAGACCTGGTCCCACACGTGCCCAAGAA ACATTTGGAAATAGAACACGTCATTCAGTTGAAACTCCAGACATCAAAGATTTAGCCAGC ACTTTAAGTAAAGAATCTGGTCAATTGCCCAACAAAAAAAATTGCAGAACGAATATAAGT TATGGGCTAGAGAATGAACCTACAGCAACTTATACAATGTTTTCTGCTTTTCAGGAAGGT AGCAAAAAATCACAAACAGATTGCATATTATCTGATACATCCCCCTCTTTCCCCTGGTAT AGACACGTTTCCAATGATAGTAGGAAAACAGATAAATTAATTGGTTTCTCCAAACCAATC GTCCGTAAGAAGCTAAGCTTGAGTTCACAGCTAGGATCTTTAGAGAAGTTTAAGAGGCAA TATGGGAAGGTTGAAAATCCTCTGGATACAGAAGTAGAGGAAAGTAATGGAGTCACTACC AATCTCAGTCTTCAAGTTGAACCTGACATTCTGCTGAAGGACAAGAACCGCTTAGAGAAC TCTGATGTTTGTAAAATCACTACTATGGAGCATAGTGATTCAGATAGTAGTTGTCAACCA GCAAGCCACATCCTTGACTCAGAGAAGTTTCCATTCTCCAAGGATGAAGATTGTTTAGAA CAACAGATGCCTAGTTTGAGAGAAAGTCCTATGACCCTGAAGGAGTTATCTCTCTTTAAT AGAAAACCTTTGGACCTTGAGAAGTCATCTGAATCACTAGCCTCTAAATTATCCAGACTG AAGGGTTCCGAAAGAGAAACTCAAACAATGGGGATGATGAGTCGTTTTAATGAACTTCCA AATTCAGATTCCAGTAGGAAAGACAGCAAGTTGTGCAGTGTGTTAACACAAGATTTTTGT ATGTTATTTAACAACAAGCATGAAAAAACAGAGAATGGTGTCATCCCAACATCAGATTCT GCCACACAGGATAATTCCTTTAATAAAAATAGTAAAACACATTCTAACAGCAATACAACA GAGAACTGTGTGATATCAGAAACTCCTTTGGTATTGCCCTATAATAATTCTAAAGTTACC GGTAAAGATTCAGATGTTCTTATCAGAGCCTCAGAACAACAGATAGGAAGTCTTGACTCT CCCAGTGGAATGTTAATGAATCCGGTAGAAGATGCCACAGGTGACCAAAATGGAATTTGT TTTCAGAGTGAGGAATCTAAAGCAAGAGCTTGTTCTGAAACTGAAGAGTCAAACACGTGT TGTTCAGATTGGCAGCGGCATTTCGATGTAGCCCTGGGAAGAATGGTTTATGTCAACAAA ATGACTGGACTCAGCACATTCATTGCCCCAACTGAGGACATTCAGGCTGCTTGTACTAAA GACCTGACAACTGTGGCTGTGGATGTTGTACTTGAGAATGGGTCTCAGTACAGGTGTCAA CCTTTTAGAAGCGACCTTGTTCTTCCTTTCCTTCCGAGAGCTCGAGCAGAGAGGACTGTG ATGAGACAGGATAACAGAGATACTGTGGATGATACTGTTAGTAGCGAATCGCTTCAGTCT TTGTTCTCAGAATGGGACAATCCAGTATTTGCCCGTTATCCAGAGGTTGCTGTTGATGTA AGCAGTGGCCAGGCTGAGAGCTTAGCAGTTAAAATTCACAACATCTTGTATCCCTATCGT TTCACCAAAGGAATGATTCATTCAATGCAGGTTCTCCAGCAAGTAGATAACAAGTTTATT GCCTGTTTGATGAGCACTAAGACTGAAGAGAATGGCGAGGCAGATTCCTACGAGAAGCAA CAGGCACAAGGCTCTGGTCGGAAAAAATTACTGTCTTCTACTCTAATTCCTCCGCTAGAG ATAACAGTGACAGAGGAACAAAGGAGACTCTTATGGTGTTACCACAAAAATCTGGAAGAT CTGGGCCTTGAATTTGTATTTCCAGACACTAGTGATTCTCTGGTCCTTGTGGGAAAAGTA CCACTATGTTTTGTGGAAAGAGAAGCCAATGAACTTCGGAGAGGAAGATCTACTGTGACC AAGAGTATTGTGGAGGAATTTATCCGAGAACAACTGGAGCTACTCCAGACCACCGGAGGC ATCCAAGGGACATTGCCACTGACTGTCCAGAAGGTGTTGGCATCCCAAGCCTGCCATGGG GCCATTAAGTTTAATGATGGCCTGAGCTTACAGGAAAGTTGCCGCCTTATTGAAGCTCTG TCCTCATGCCAGCTGCCATTCCAGTGTGCTCACGGGAGACCTTCTATGCTGCCGTTAGCT GACATAGACCACTTGGAACAGGAAAAACAGATTAAACCCAACCTCACTAAACTTCGCAAA ATGGCCCAGGCCTGGCGTCTCTTTGGAAAAGCAGAGTGTGATACAAGGCAGAGCCTGCAG CAGTCCATGCCTCCCTGTGAGCCACCATGA Clone variation with respect to NM_014381.2 1687 c=>t;2476 a=>g;4263 a=>g >OriGene 5' read for NM_014381 unedited
NGGTTCACAATTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGCGCACGAGC CTCAAGACCAGGTGCGCGCGTCGGCGTCCGAGGCGGTTGGTGTCGGAGAATTTGTTAAGC GGGACTCCAGGCAATTATTTCCAGTCAGAGAAGGAAACCAGTGCCTGGCATTCTCACCAT CTTTCTACCTACCATGATCAAGTGCTTGTCAGTTGAAGTACAAGCCAAATTGCGTTCTGG TTTGGCCATAAGCTCCTTGGGCCAATGTGTTGAGGAACTTGCCCTCAACAGTATTGATGC TGAAGCAAAATGTGTGGCTGTCAGGGTGAATATGGAAACCTTCCAAGTTCAAGTGATAGA CAATGGATTTGGGATGGGGAGTGATGATGTAGAGAAAGTGGGAAATCGTTATTTCACCAG TAAATGCCACTCGGTACAGGACTTGGAGAATCCAAGGTTTTATGGTTTCCGAGGAGAGGC CTTGGCAAATATTGCTGACATGGCCAGTGCTGTGGAAATTTCGTCCAAGAAAAACAGGAC AATGAAAACTTTTGTGAAACTGTTTCAGAGTGGAAAAGCCCTGAAAGCTTGTGAAGCTGA TGTGACTAGAGCAAGCGCTGGGACTACTGTAACAGTGTATAACCTATTTTACCAGCTNTC CTGTAGGAGGAAATGCATGGACCCTAGACTGGAGTTTGAGAAGGTTAGGCAGAGAATAGA AGCTCTCTCACTCATGCACCCTTCCATTTCTTTCTCTTTGAGAAATGATGTTTCTGGTTC CATGGTTCCTCAGCTCCCCTAAACCAAAGACGTATGTTCCCGATTTTGTCAATTTATGGA TGGNGAAAGTCCCAAAGCTAAGAGAATAAGTTTAAATTTAAAGAGTTGAGCTTATGGCTT ATCAGCTCTGAGCCCTTACACAAGAATTGCAGTTTTA >OriGene 3' read for NM_014381 unedited
ACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTCAAACTGTCATTAAAT TTTATCATTAAATAAGTAGCAAAAGGTAGATACTATATAGCAACCTTCTGTGCCCATGGA TGCAAATGAATGAATTGTCTTTAGGCTTGAATTTCATCTGGCTACTCAACTAGGGGAATC ATCTGCTCAAGAAAGACTGATACAGAGAGCCCTGCTGTCTAAGCTGCTCAGGGACACTGG GCTGATTCAGTCAGGGCCGTGCTGGTACCTGCTGCTGCTGCTCTCTGCTCAGAGGCATAC AGTGAACATCCCTTTGTTCCTTTTAGACCAGTGATTCTGTCTTCATGGTGGCTCACAGGG AGGCATGGACTGTTGCAGGCCTCTGCCTTGTATCACACTCTGCTTTCTCCAAGCACACGC CAGTCCTGGGCCCCTTCGCTCAATTCCCTGCGGCCCCCCTTATCCCCCTTTTCCTGTCCC CTCCCCCCCCCCTCTCCCTCCCCTCTCTCCCTCCTCCCCTCTCCCCCTTTTCCCCTTTCC CCTCCCCCCATTCCCTCCATTCCTCCTCCTCTCTCCTCTCCCTTTTTCCCCTCCCCTCCC CCTTCCTTTCTCTTCCCCCTCCCTTCCCCCTTTTTTTTCTCCCCCCCCTCCCCCCCCCTT TCCCCCCTTCCCCCCATCTCTCTCCTCCCCTACCTCATTCTGCCTCCCCCCACCCCTCTT TCATTTCCTTCCCACCCCCCATCTCCCTCTTCTCCCCCCTCTCCCCCCTTTCCCCTTTTC CTCCCTCCCTTTTCCCTTCTTTCCCTCCTCCCCCCTCCCCTTTCTCCCCCCCCCCCTTTC CCCTTCCTCCTCTTCCTCCCCTCCCCCCCTCTATCCCCCCTCCTCTCCCCTTTTTTTTCC CCATCCCCCCTCTTTCTTTCCTTTTACTCCCCCCCCCCCCCTCTTCCTTTCACCTCCCCC CTTCTTACTCCTCATTACT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014381 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_014381.1, NP_055196.1 |
| RefSeq Size | 4895 bp |
| RefSeq ORF | 4290 bp |
| Locus ID | 27030 |
| Domains | HATPase_c |
| Protein Families | Druggable Genome |
| Protein Pathways | Mismatch repair |
| Gene Summary | This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2), also known as delta7, lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212150 | MLH3 (Myc-DDK-tagged)-Human mutL homolog 3 (E. coli) (MLH3), transcript variant 2 |
CNY 9,776.00 |
|
| RC212150L3 | Lenti ORF clone of Human mutL homolog 3 (E. coli) (MLH3), transcript variant 2, Myc-DDK-tagged |
CNY 16,150.00 |
|
| RC212150L4 | Lenti ORF clone of Human mutL homolog 3 (E. coli) (MLH3), transcript variant 2, mGFP tagged |
CNY 16,150.00 |
|
| RG212150 | MLH3 (tGFP-tagged) - Human mutL homolog 3 (E. coli) (MLH3), transcript variant 2 |
CNY 11,376.00 |
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