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LRRC8A (NM_019594) Human Untagged Clone
CAT＃: SC127734
LRRC8A (untagged)-Human leucine rich repeat containing 8 family, member A (LRRC8A), transcript variant 2
CNY 5,944.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AGM5; HsLRRC8A; LRRC8; SWELL1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127734 sequence for NM_019594 edited (data generated by NextGen Sequencing)
ATGATTCCGGTGACAGAGCTCCGCTACTTTGCGGACACGCAGCCAGCATACCGGATCCTG AAGCCGTGGTGGGATGTGTTCACAGACTACATCTCTATCGTCATGCTGATGATTGCCGTC TTCGGGGGGACGCTGCAGGTCACCCAAGACAAGATGATCTGCCTGCCTTGTAAGTGGGTC ACCAAGGACTCCTGCAATGATTCGTTCCGGGGCTGGGCAGCCCCTGGCCCGGAGCCCACC TACCCCAACTCCACCATTCTGCCGACCCCTGACACGGGCCCCACAGGCATCAAGTATGAC CTGGACCGGCACCAGTACAACTACGTGGACGCTGTGTGCTATGAGAACCGACTGCACTGG TTTGCCAAGTACTTCCCCTACCTGGTGCTTCTGCACACGCTCATCTTCCTGGCCTGCAGC AACTTCTGGTTCAAATTCCCGCGCACCAGCTCGAAGCTGGAGCACTTTGTGTCTATCCTG CTGAAGTGCTTCGACTCGCCCTGGACCACGAGGGCCCTGTCGGAGACAGTGGTGGAGGAG AGCGACCCCAAGCCGGCCTTCAGCAAGATGAATGGGTCCATGGACAAAAAGTCATCGACC GTCAGTGAGGACGTGGAGGCCACCGTGCCCATGCTGCAGCGGACCAAGTCACGGATCGAG CAGGGTATCGTGGACCGCTCAGAGACGGGCGTGCTGGACAAGAAGGAGGGGGAGCAAGCC AAGGCGCTGTTTGAGAAGGTGAAGAAGTTCCGGACCCATGTGGAGGAGGGGGACATTGTG TACCGCCTCTACATGCGGCAGACCATCATCAAGGTGATCAAGTTCATCCTCATCATCTGC TACACCGTCTACTACGTGCACAACATCAAGTTCGACGTGGACTGCACCGTGGACATTGAG AGCCTGACGGGCTACCGCACCTACCGCTGTGCCCACCCCCTGGCCACACTCTTCAAGATC CTGGCGTCCTTCTACATCAGCCTAGTCATCTTCTACGGCCTCATCTGCATGTACACACTG TGGTGGATGCTACGGCGCTCCCTCAAGAAGTACTCGTTTGAGTCGATCCGTGAGGAGAGC AGCTACAGCGACATCCCCGACGTCAAGAACGACTTCGCCTTCATGCTGCACCTCATTGAC CAATACGACCCGCTCTACTCCAAGCGCTTCGCCGTCTTCCTGTCGGAGGTGAGTGAGAAC AAGCTGCGGCAGCTGAACCTCAACAACGAGTGGACGCTGGACAAGCTCCGGCAGCGGCTC ACCAAGAACGCGCAGGACAAGCTGGAGCTGCACCTGTTCATGCTCAGTGGCATCCCTGAC ACTGTGTTTGACCTGGTGGAGCTGGAGGTCCTCAAGCTGGAGCTGATCCCCGACGTGACC ATCCCGCCCAGCATTGCCCAGCTCACGGGCCTCAAGGAGCTGTGGCTCTACCACACAGCG GCCAAGATTGAAGCGCCCGCGCTGGCCTTCCTGCGCGAGAACCTGCGGGCGCTGCACATC AAGTTCACTGACATCAAGGAGATCCCGCTGTGGATCTATAGCCTGAAGACACTGGAGGAG CTGCACCTGACGGGCAACCTGAGCGCGGAGAACAACCGCTACATCGTCATCGACGGGCTG CGGGAGCTCAAACGCCTCAAGGTGCTGCGGCTCAAGAGCAACCTAAGCAAGCTGCCACAG GTGGTCACAGATGTGGGCGTGCACCTGCAGAAGCTGTCCATCAACAATGAGGGCACCAAG CTCATCGTCCTCAACAGCCTCAAGAAGATGGCGAACCTGACTGAGCTGGAGCTGATCCGC TGTGACCTGGAGCGCATCCCCCACTCCATCTTCAGCCTCCACAACCTGCAGGAGATTGAC CTCAAGGACAACAACCTCAAGACCATCGAGGAGATCATCAGCTTCCAGCACCTGCACCGC CTCACCTGCCTTAAGCTGTGGTACAACCACATCGCCTACATCCCCATCCAGATCGGCAAC CTCACCAACCTGGAGCGCCTCTACCTGAACCGCAACAAGATCGAGAAGATCCCCACCCAG CTCTTCTACTGCCGCAAGCTGCGCTACCTGGACCTCAGCCACAACAACCTGACCTTCCTC CCTGCCGACATCGGCCTCCTGCAGAACCTCCAGAACCTAGCCATCACGGCCAACCGGATC GAGACGCTCCCTCCGGAGCTCTTCCAGTGCCGGAAGCTGCGGGCCCTGCACCTGGGCAAC AACGTGCTGCAGTCACTGCCCTCCAGGGTGGGCGAGCTGACCAACCTGACGCAGATCGAG CTGCGGGGCAACCGGCTGGAGTGCCTGCCTGTGGAGCTGGGCGAGTGCCCACTGCTCAAG CGCAGCGGCTTGGTGGTGGAGGAGGACCTGTTCAACACACTGCCACCCGAGGTGAAGGAG CGGCTGTGGAGGGCTGACAAGGAGCAGGCCTGA Clone variation with respect to NM_019594.3 1014 t=>c;1509 c=>t >OriGene 5' read for NM_019594 unedited
ACTCACTATAGGGGCGGCCGCGAATCGGTACGAGGCTGCGGCCGGCGGCGGGACGGAGCG GCCGGGGCCTGGGGCTGCCTGCCGGGCGGCCGGGCGCGGCGAGCCCAGGGAGGCAGCGTC CATGGAGCAAAAGGAATGCCAGGATCCTGCACAGGCAGACGCGGGCCAGCCTCAGCACCG ACAGCCGACGCGCAGATAGCAGAGCCATCCTTGGGGTTGAACCATGATTCCGGTGACAGA GCTCCGCTACTTTGCGGACACGCAGCCAGCATACCGGATCCTGAAGCCGTGGTGGGATGT GTTCACAGACTACATCTCTATCGTCATGCTGATGATTGCCGTCTTCGGGGGGACGCTGCA GGTCACCCAAGACAAGATGATCTGCCTGCCTTGTAAGTGGGTCACCAAGGACTCCTGCAA TGATTCGTTCCGGGGCTGGGCAGCCCCTGGCCCGGAGCCCACCTACCCCAACTCCACCAT TCTGCCGACCCCTGACACGGGCCCCACAGGCATCAAGTATGACCTGGACCGGCACCAGTA CAACTACGTGGACGCTGTGTGCTATGAGAACCGACTGCACTGGTTTGCCAAGTACTTCCC CTACCTGGTGCTTCTGCACACGCTCATCTTCCTGGCCTGCAGCAACTTCTGGTTCAAATT CCCGCGCACCAGCTCGAAGCTGGAGCACTTTGTGTCTATCCTGCTGAAGTGCTTCGACTC GCCCTGGGACCACGAGGCCCTGTCGGAGACAGTGGTGGNAGAGAGCGACCCCAAGCCGGC CTTCAGCAGATGAATGGGTCCATGGGACAAAGTCATCGACCGGTCAGTGAGACGTGGAGG CACCGTNGCCATGCTGCC >OriGene 3' read for NM_019594 unedited
TCTATGGACGCGGCCGCTTTCTANAGTCGAGTTTTTTTTTTTTTTTTTTAATACCCAAAC CATCCATTTTCAAAGCTTTTTTTTTAAAAAAATGTTTTTTGATTAAAAAAAAAAAAACAA AAAACTAAAACTGCCACAAATACTGAAGAGGCAAGCTCCAGGCCTGGCCTTTCCAGCTGG AGGCCTGCTCTCCCGTGGACCGCACCGCAGAGCCCAGCCCGGCACTGCTGGGTGACCGTC CCATGGCTGGTTCGCCCCGGACCACTCTGCTGAAGTCCAGGTGGGTGTTAAATGCCCGGC GGCATCGCTAAATAAGGACAAGGGGAAAAGGCAGCCCACCTTTCCCTGAACACCTTCCAT CTGGGCTGAACTTTCTTGGGAATGTATAAGTTATCTGGATGAAGGAGGCGGGAGATGGAG AAAAATAAATACCAAGAACTAAAGTGAGGGTCCCAGGACCTCTGGTGGCAGCTCAGCCCC TGGGGCAGAGCTGGCCTCCAGGGAGGAGACCCTGATTATCCAAATACTGCGCTCTTGAGA CTTGCTCTCCTCCACAAGCACTTGCCCTGGGGGACGTGAGTCTCAGAGGGAGAAAAGGGG CCAGCCCCACAGATACTGTCCTCTCGCTCTGGCCTGACTCACAAGCGGCCCCAGGCTCCT GCCCAGCCACGAGCTGTCCTGCCTGTCCGGGAGTTCTGGGAGAACCTAGGCCTGCCCCTC CGGCCCTGAGGACCTGGCAGCGGTCCTGCTGCTTGCTGTGCTGGGCCCGCCTCGCTCAAC CCTGCTCCTTTGTAGCCCCTCCAAGCCGGTCTCTCACCTNGGGTGGAAGGGTGTGAACAG TCCCTCTACACCACAAACCGNTGNGCTTGACCAGGGGNACTCCCCAGCTTCAAGGCAGAA CTCCACCCGNTGCCCCCACTTAACTGGTCAGGTGCACACC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_019594 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_019594.2, NP_062540.2 |
| RefSeq Size | 4296 bp |
| RefSeq ORF | 2433 bp |
| Locus ID | 56262 |
| UniProt ID | Q8IWT6 |
| Protein Families | Transmembrane |
| Gene Summary | This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All variants (1-3) encode the same protein. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208632 | LRRC8A (Myc-DDK-tagged)-Human leucine rich repeat containing 8 family, member A (LRRC8A), transcript variant 2 |
CNY 5,936.00 |
|
| RC208632L1 | Lenti ORF clone of Human leucine rich repeat containing 8 family, member A (LRRC8A), transcript variant 2, Myc-DDK-tagged |
CNY 8,336.00 |
|
| RC208632L2 | Lenti ORF clone of Human leucine rich repeat containing 8 family, member A (LRRC8A), transcript variant 2, mGFP tagged |
CNY 8,336.00 |
|
| RC208632L3 | Lenti ORF clone of Human leucine rich repeat containing 8 family, member A (LRRC8A), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208632L4 | Lenti ORF clone of Human leucine rich repeat containing 8 family, member A (LRRC8A), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG208632 | LRRC8A (tGFP-tagged) - Human leucine rich repeat containing 8 family, member A (LRRC8A), transcript variant 2 |
CNY 4,370.00 |
