MARK1 (AK098103) Human Untagged Clone

CAT#: SC127474

(untagged)-Human cDNA FLJ40784 fis, clone TRACH2006331, moderately similar to Human MARK (MARK) mRNA



CNY 5,640.00

CNY 6,270.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00


Rabbit Polyclonal Anti-MARK1 Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms MARK; Par-1c; Par1c
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for AK098103, the custom clone sequence may differ by one or more nucleotides


ACCTTCACCCATGGTCCGGAGAGCCTAGCGGGGCTCGCCACCGCCTCCCGGCTCCCCTTCCACGCCTCAT
CCTGCCAGCCTCGCCGCCCCGCCAGCGCCGGGCAACCGCCTCGCCCGAAGCCCTCCCTCGTTACTGTCCG
CATACCCCGGCGGCGCCGCCGCGGGAAGCGGCTCCCCCGCACCACAGCCCGGCCGGCGAGACCCCGGCCA
GACCCCGCTGCCCGCACAAAATGTCGGCCCGGACGCCATTGCCGACGGTGAACGAGCGGGACACGGAAAA
TCATACATCTGTGGATGGATATACTGAACCACACATCCAGCCTACCAAGTCGAGTAGCAGACAGAACATC
CCCCGGTGTAGAAACTCCATTACGTCAGCAACAGATGAACAGCCTCACATTGGAAATTACCGTTTACAAA
AAACAATAGGGAAGGGAAATTTTGCCAAAGTCAAATTGGCAAGACACGTTCTAACTGGTAGAGAGGTTGC
TGTGAAAATAATAGACAAAACTCAGCTAAATCCTACCAGTCTACAAAAGGTATTTAATTAATTTAATAAG
TAATTAAAATGTGAGTTTATCATTAATATGTGATGTTCTGTAAAATCAGTCATTCTAAATTTTCTATTAG
GTACAATTCTACATTTCATCAATATAAGAAGAAAAGACATAATATAAAATGTAATGTTTATGACTTACCA
AGTAGTTGCTTGAAAACTATCTACTACTTAAATACATGTAGTATATGAAAGAAATGTATCTCTTCTATTC
AATAGAATAAAACCTTGTGTCATACATTTTGAAGTATTCAGGATTTGAAATATTCAAATATTTTGAAGTA
TTTTCAAGTATTCAGAATTGACCTCTGAAAATTAGACTTATATTAAATGAATAATCCATTTACTGATAAT
ATCTGGTGCCTTAGCTGTTATATAAAATGACAAATGGTGGTGACCTAAGCCATTTAAACTTTTGTGAGTT
TTCAGATAAAGTCCAGAGACCTTGCTGATAAGCTTCTTAATTAAAAATCTAGTTAGAAGTTAATATTGTT
CATAGGTGAGTTTCCTTTTATTGCTTCATTTGCTCTTCTTCCTTCTTCCACAAGAACTACTAGTCTTTCA
GATAACTCACAGTACAAAATAAGAATGTTTCTTTAAAGGATTGAAAATATGAAACAACATAGAGAGAAAA
GAAAGCAGTTAGGAAGGGGATTGCCTTAGCAAACCAAAGCTGTTTCACGTTACTTCATTAATTACTTAAA
TGGGAAAATTTTCTCAGATGCACATTTTAGTACTTTAAAAATGAAGCAAATGTTTTAACATTTATGCTGT
ATGTGATAGGTTTGTATAGAGTGAGAGAATATACATTGTGACTTTTATTAGAATATAATGGGACCATTGT
CACATATGTAATTTTAATACAAATGACTTTGAATTCCTAAAACAGAAAGAATCTTATAAGAAATTGTTAG
TATGTGTGCTTACATCTGCTATGATTATAGCATTAGATTAAAAATTTAGATTTGTGATATTCAAACTTTC
TTCTCATTTGGCTCAGTCCCAGATTTCTTCTTAGAGCTCTGCCTTTGTACTTATCGGAGATTCTTTTGAA
AATTTGACAACCAGTATAACTTTTCATAACACTGATATTTCTGCCCAGTAAGAACATGAAAACTTTGCTG
GGTTCTTCTTTTTCTGTGAATGTGAGATAATGTATTATGGGTCTCTTCTTGGAGAAAGTCTCTTCTTTTA
GCACCAGTCTTTTTGCTAACCATGATGCCTTTGTGTAAGTGAGAAAAAGACATCCTACCTGGACCAATTA
ACTATGCAAAGATGCTGTTTTTTACTGGGCTGGAACCACAGTAGGACATATCTTTGCCTACCCCTGTGCT
GGGAACCCACTTAAAATGCACAAACTGGGTAATTGTACACAGTGTCCCTGTCCATGGCCCACATAGCTTT
TCTACTTTTCCTGGATTTAGTTGTGGGTTACTTGGCAAATTGAGTGATTTTTAAGTGGCATCTAGAACTA
CTCAGGCCTGTTGTGCTAGCTGGAATACACAGCAATGCGACTCCTACTCTGTCTTTCCCAAGGTTGTATA
AACAAAGTTGTACTTATTGAAACATGTGAACATGAAACTGAATGTTGCTTTCTTTATCTGAATAACTAAA
ACGTGTACTTGATGATGATAAGTAATTTCTGTCATAAAATCTACTAATCTTGTTGATAAAGTATTGCTTT
TCCAAATAGGCATATAAAAATGATACAATTTTGTTTTCTTTAACCCGTGAAAATAAAGATGAAGACTCAC
T


>OriGene 5' read for AK098103 unedited
TTGTAATACGACTCACTATAGGGGCGGCCGCGAATTCGCACGAGGCGCCTCGCCCGAAGC
CCTCCCTCGTTACTGTCCGCATACCCCGGCGGCGCCGCCGCGGGAAGCGGCTCCCCCTCC
TCTTCCTCCGCGTCCTCTTCCCTCTTTCCCCCGCCGGGGCCGCTTGTTGCACCGCCCCGC
GGCCTGCGGGAGCCGCTCGCCCCGGCCTTGTGCTCGCGTCCGCACCCCTTTCCTGTCGCC
CCCCGGGGCCCGCACCACAGCCCGGCCGGCGAGACCCCGGCCAGACCCCGCTGCCCGCAC
AAAATGTCGGCCCGGACGCCATTGCCGACGGTGAACGAGCGGGACACGGAAAATCATACA
TCTGTGGATGGATATACTGAACCACACATCCAGCCTACCAAGTCGAGTAGCAGACAGAAC
ATCCCCCGGTGTAGAAACTCCATTACGTCAGCAACAGATGAACAGCCTCACATTGGAAAT
TACCGTTTACAAAAAACAATAGGGAAGGGAAATTTTGCCAAAGTCAAATTGGCAAGACAC
GTTCTAACTGGTAGAGAGGTTGCTGTGAAAATAATAGACAAAACTCAGCTAAATCCTACC
AGTCTACAAAAGGTATTTAATTAATTTAATAAGTAATTAAAATGTGAGTTTATNCATTAA
TATGTGATGGTTCTGTAAAATCAGTCATTCTAAATTTTCTATTAGGTACAATTCTACATT
TCATCAATATAAGAAGAAAAGACATATATNAAATGGTATGTTTATGACTTACAAAGTAGT
TGCTTGAAACTATCTACTACTTAATACATGTAGATATGAAAGAATGTATCTCTTTATTCA
TAGATAAACCCTGTGTCTACATTNTGAAGATNCAGGATTNGAAT
Restriction Sites NotI-NotI     
ACCN AK098103
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq AK098103.1
RefSeq Size 2311 bp
RefSeq ORF 2311 bp
Locus ID 4139
Protein Families Druggable Genome, Protein Kinase
Gene Summary Serine/threonine-protein kinase (PubMed:23666762). Involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed:23666762). Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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