KREMEN2 (NM_024507) Human Untagged Clone
CAT#: SC127217
KREMEN2 (untagged)-Human kringle containing transmembrane protein 2 (KREMEN2), transcript variant 2
CNY 7,220.00
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | KRM2 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for NM_024507, the custom clone sequence may differ by one or more nucleotides
ATGGGGACACAAGCCCTGCAGGGCTTCCTCTTTCTCCTCTTCCTCCCGCTGCTGCAGCCGCGTGGGGCCT CGGCTGGGAGCCTGCACAGTCCAGGCCTGTCCGAATGCTTCCAGGTGAATGGGGCTGACTACCGCGGCCA CCAGAACCGCACTGGCCCGCGCGGGGCGGGCCGCCCGTGCCTCTTCTGGGACCAGACGCAGCAACACAGC TACAGCAGCGCCAGCGACCCCCACGGCCGCTGGGGGCTGGGCGCGCACAACTTCTGCCGTAACCCAGACG GTGACGTGCAGCCGTGGTGCTACGTGGCTGAGACAGAGGAGGGCATCTACTGGCGCTACTGCGACATCCC CTCCTGTCACATGCCAGGCTACCTGGGATGCTTTGTGGACTCAGGGGCACCCCCAGCCCTCAGCGGCCCC AGCGGCACCTCCACGAAGCTCACGGTCCAGGTGTGCCTACGCTTCTGCCGCATGAAGGGGTACCAGCTGG CGGGCGTGGAGGCCGGTTACGCCTGCTTCTGTGGCTCTGAAAGCGACCTGGCCCGGGGACGCCTGGCCCC CGCCACCGACTGTGACCAGATCTGTTTCGGCCACCCTGGACAGCTGTGTGGCGGCGATGGGCGGCTGGGC GTCTATGAAGTGTCGGTGGGCTCCTGCCAGGGGAACTGGACAGCGCCTCAGGGCGTCATCTACTCCCCGG ACTTCCCGGACGAGTACGGGCCGGACCGGAACTGCAGCTGGGCCCTGGGCCCGCCAGGCGCCGCGCTGGA GCTCACCTTCCGCCTCTTCGAGCTGGCCGACCCGCGCGACCGGCTGGAGCTGCGCGACGCGGCTTCGGGC AGCCTGCTCCGCGCCTTCGATGGCGCCCGCCCACCGCCGTCCGGGCCGCTGCGCCTGGGCACTGCCGCGC TGCTGCTCACCTTCCGAAGCGACGCGCGCGGCCACGCGCAAGGCTTCGCGCTCACCTACCGCGGGCTGCA GGACGCCGCTGAGGACCCAGAGGCCCCCGAGGGCTCGGCCCAGACCCCCGCGGCGCCCCTCGACGGGGCC AACGTGAGCTGCAGCCCCAGGCCTGGGGCTCCGCCGGCCGCGATTGGGGGAGCTGTCTGCTGGCTCCGGG AAAAGGGCCCCCGGCGCTGGGGGCTTCCAGGGGCCCCAGGAGAAGCTGGGCTGTGTGGTACCAACAGCCC CGAGGGGTGGCCTTGCCCTGCTCCCCCGGGGACCCCCAGGCTGAGGGTTCTGCCGCGGGCTACCGGCCTC TGA >OriGene 5' read for NM_024507 unedited
NAAAACATTTCACATTTGTATACGACTCATATAGGCGGCACGCGAATTCGCACGAGGGGG TATACTGTCAGAGGACAACGCCCCCTAGGTCTCCTGGGAGACCCCGAAGCGACCCCGGGG GCAGCCCGGGCCGTGTCCGGGCGAGGGTGACCTATCCTTGGTTGAGAGCGATGGGGACAC AAGCCCTGCAGGGCTTCCTCTTTCTCCTCTTCCTCCCGCTGCTGCAGCCGCGTGGGGCCT CGGCTGGGAGCCTGCACAGTCCAGGCCTGTCCGAATGCTTCCAGGTGAATGGGGCTGACT ACCGCGGCCACCAGAACCGCACTGGCCCGCGCGGGGCGGGCCGCCCGTGCCTCTTCTGGG ACCAGACGCAGCAACACAGCTACAGCAGCGCCAGCGACCCCCACGGCCGCTGGGGGCTGG GCGCGCACAACTTCTGCCGTAACCCAGACGGTGACGTGCAGCCGTGGTGCTACGTGGCTG ATACAGAGGAGGGCATCTACTGGCGCTACTGCGACATCCCCTCCTGTCACATGCCAGGCT ACCTGGGATGCTTTGTGGACTCAGGGGCACCCCCAGCCCTCAGCGGCCCCAGCGGCACCT CCACGAAGCTCACGGTCCAGGTGTGCCTACGCTTCTGCCGCATGAAGGGGTACCAGCTTG GCGGGCGTGGAGGCCCGTTACGCCTGCTTCTGTGGCTCTGAAAGCGACCTGGCCCCGGTG ACCCCTGGGCCCCGCCACCGAATGGGACCAGATCTGTTTCGGCCACNCTGGGAAGCTGTG TGGCGGCCATGGGCGGCTGGGCGTCTATGAAGGTGCGTGGGCTCCTGCCAGGGGAACTGG ACAGCGCCTCATGGGGTCATCTACTCT >OriGene 3' read for NM_024507 unedited
GACCTTTGGCGATGTGCACTTCCCAGTTCCAGNANAGCACTGGGGCAGGGTCACAGGCAT GCCACCCGGGTATCTGTTGCAGGAAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAG TTTTTTTTTTTTTTTTTTACCAAAGTAGATCCTTTATTCAAAATCTGTGGGGGTTTTTTG ACTGTTTTTGCTGACCTGTGACCTCTCACTGAGGACGGCAGTCCAGGACCACCCCCAGAG GGGTTCAAAGACCTCCGAAACCAGAGACCACCCCCACATACAGGTCCATGGAGAGGGCCT GGACCATCTGGACCCCCACGGTCAGGCCAAGTCCCAGATAATAGCACCAGATGTTTCCTG TCCGACTTTTGGTCTCCCCAAGGCGACCAGAGGCCGAGCTGCCCCTACACAGGCGCAAGG CCGAGGCAGGGCGCAGCACAGCATCTCAGGTGTCCATCTCGCCGGCGGCGGGCCCAGCGG ACCCTCGGGGCCCAGAGTCAGAGAGCGGATATGAGCGAGCGCAGGGAGCTCTGGCTGGAG GCACTCAGAGGCCGGTAGCCCGCGGCAGAACCCTCAGCCTGGGGGTCCCCGGGGGAGCAG GGCAAGGCCACCCCTCGGGGCTGTTGGTACCACACAGCCCATCTTCTCCTGGGGCCCCTG GAAGCCCCCAGCGCCGGGGGCCCTTTTCCCGGAGCCAGCAGACAGCTCCCCCAATCGCGG CCGGCGGAGCCCCAGCCTGGGGCTGCAGCTCACGTTGGCCCCGTCGAGGGGCGCCGCGGG GGTCTGGGCCGAGCCCTCGGGGGCCTCTGGGTCCTCAGCGGCGTCCTGCAACCCGCGTAG GTGAGCGCAAGCCCTGCGCGTGGCCCGCGCGTCGCTCGGAGGTGAGCAGCACGCGGAGTG CCCAGCGCAGCGCCCN |
Restriction Sites | Please inquire |
ACCN | NM_024507 |
Insert Size | 2000 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_024507.2, NP_078783.1 |
RefSeq Size | 1992 bp |
RefSeq ORF | 1263 bp |
Locus ID | 79412 |
UniProt ID | Q8NCW0 |
Protein Families | Druggable Genome, Transmembrane |
Gene Summary | This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] Transcript Variant: This variant (2), also called kremen2b, lacks an exon in the 3' coding region compared to variant 4, resulting in a frameshift. The encoded isoform (b) is shorter and has a distinct C-terminus compared to isoform d. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC202558 | KREMEN2 (Myc-DDK-tagged)-Human kringle containing transmembrane protein 2 (KREMEN2), transcript variant 2 |
CNY 3,656.00 |
|
RC202558L1 | Lenti ORF clone of Human kringle containing transmembrane protein 2 (KREMEN2), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC202558L2 | Lenti ORF clone of Human kringle containing transmembrane protein 2 (KREMEN2), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
RC202558L3 | Lenti ORF clone of Human kringle containing transmembrane protein 2 (KREMEN2), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC202558L4 | Lenti ORF clone of Human kringle containing transmembrane protein 2 (KREMEN2), transcript variant 2, mGFP tagged |
CNY 6,056.00 |
|
RG202558 | KREMEN2 (tGFP-tagged) - Human kringle containing transmembrane protein 2 (KREMEN2), transcript variant 2 |
CNY 5,256.00 |
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