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PAK1 interacting protein 1 (PAK1IP1) (NM_017906) Human Untagged Clone
CAT＃: SC127179
PAK1IP1 (untagged)-Human PAK1 interacting protein 1 (PAK1IP1)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | bA421M1.5; hPIP1; MAK11; PIP1; WDR84 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC127179 sequence for NM_017906 edited (data generated by NextGen Sequencing)
ATGGAGCTGGTCGCTGGTTGCTACGAGCAGGTCCTCTTTGGGTTCGCTGTACACCCGGAG CCCGAGGCTTGCGGCGACCACGNNNNATGGACTCTTGTGGCTGACTTCACTCACCATGCT CACACTGCCTCCTTGTCAGCAGTAGCTGTAAATAGTCGTTTTGTGGTCACTGGGAGCAAA GATGAAACAATTCACATTTATGACATGAAAAAGAAGATTGAGCATGGGGCTCTAGTGCAT CACAGTGGTACAATAACTTGCCTGAAATTCTATGGCAACAGGCATTTAATCAGTGGAGCG GAAGATGGACTCATCTGTATCTGGGATGCAAAGAAATGGGAATGCCTGAAGTCAATTAAA GCTCACAAAGGACAGGTGACCTTCCTTTCTATTCACCCATCTGGCAAGTTGGCCCTGTCG GTTGGTACAGATAAAACTTTAAGAACGTGGAATCTTGTAGAAGGAAGATCAGCATTCATA AAAAATATAAAACAAAATGCTCACATAGTAGAATGGTCCCCAAGAGGAGAGCAGTATGTA GTTATCATACAGAATAAAATAGACATCTATCAGCTTGACACTGCATCCATTAGTGGCACC ATCACAAATGAAAAGAGAATTTCCTCTGTTAAATTTCTTTCAGAGTCTGTCCTTGCAGTG GCTGGAGATGAAGAAGTTATAAGGTTTTTTGACTGTGATTCACTAGTGTGCCTCTGCGAA TTTAAAGCTCATGAAAACAGGGTAAAGGACATGTTCAGTTTTGAAATTCCAGAGCATCAT GTTATTGTTTCAGCATCGAGTGATGGTTTCATCAAAATGTGGAAGCTTAAGCAGGATAAG AAAGTTCCCCCATCTTTACTCTGTGAAATAAACACTAATGCCAGGCTGACGTGTCTTGGA GTGTGGCTAGACAAAGTGGCAGACATGAAAGAAAGCCTTCCTCCAGCTGCAGAGCCTTCT CCTGTAAGTAAAGAACAGTCCAAAATTGGCAAAAAGGAGCCTGGTGACACAGTGCACAAA GAAGAAAAGCGGTCAAAACCTAACACAAAGAAACGCGGTTTAACAGGTGACAGTAAGAAA GCAACAAAAGAAAGTGGCCTGATATCAACCAAGAAGAGGAAAATGGTAGAAATGTTGGAA AAGAAGAGGAAAAAGAAGAAAATAAAAACAATGCAGTGA Clone variation with respect to NM_017906.2 83 a=>n;84 g=>n;85 c=>n;86 a=>n >OriGene 5' read for NM_017906 unedited
TCAAATTTTGTAATACGACTCACTATTAGGGCGGCCGCGATTCGGCACCAAATCTTTACT TATTCTCTTCTTGGAAAATCCATGTGACCTCCCCGCGCTTAAAGTGTTTCCACGTTACAG GCGACTTAAAGGCAGCCCTGGAGCCTGACGTATAATTCGAGCGCCGATGCAGAAAGGAGT CAGGTGTTTTTTTTTTTTTTTTTTTTGGTTTCCGGTTCTGTCACCTCCAGGCTGAGCCGG GCTGGCGGAAGAGGCACGTGCGCTGCTGAATGGAGCTGGTCGCTGGTTGCTACGAGCAGG TCCTCTTTGGGTTCGCTGTACACCCGGAGCCCGAGGCTTGCGGCGACCACGAGCAGCAAT GGACTCTTGTGGCTGACTTCACTCACCATGCTCACACTGCCTCCTTGTCAGCAGTAGCTG TAAATAGTCGTTTTGTGGTCACTGGGAGCAAAGATGAAACAATTCACATTTATGACATGA AAAAGAAGATTGAGCATGGGGCTCTAGTGCATCACAGTGGTACAATAACTTGCCTGAAAT TCTATGGCAACAGGCATTTAATCAGTGGAGCGGAAGATGGACTCATCTGTATCTGGGATG CAAAGAAATGGGAATGCCTGAAGTCAATTAAAGCTCACAAAGGACAGGTGACCTTCCTTT CTATTCACCCATCTGGCAAGTTGGCCCTGTCGGTTGGTACAGATAAAACTTTAAGAACGT GGAATCTTGTAGAAGGAAGATCAGCATTCATAAAAAATATAAAACAAAATGCTCACATAG TNAGAATGGTNCCCAAGAGAGAGCAGTNTGTAGTATCATACAGAATAAATAGACTCTATC AGCTTGCACTGCATCCATTAGTGGCACCTCACAATGAAAGAGAATTNNCTCTGTAATTNC TTTANAGTCTGCCTTTGCATGGCTGAATGNAAAAGTATAAGGNTTTTTGACTGGATTCAC TANGTGCCTTGCGAATTAAGCCATGAAACAGGTAAGACATGTTCAGTTTGAATCC >OriGene 3' read for NM_017906 unedited
GGGGATTCTGTGGACCACGGACCGCATTTTNAGGATCGAGTTTTTTTCTTTTTTTTTTAA AAAAAACCTCTAAAATGGTTTTTTAATATATATATTTTTTCCAAAGGAAAAAATTTCTTG CTTTTACTCAGGGGAAAAAAAAAAAATTAAGGTACATTTGGAGTAGAATGATTTCATCTA AAAGAGTTCTTTCAGGAGACATCTGTGATTCACTGCATTGTTTTTATTTTCTTCTTTTTC CTCTTCTTTTCCAACATTTCTACCATTTTCCTCTTCTTGGTTGATATCAGGCCACTTTCT TTTGTTGCTTTCTTACTGTCACCTGTTAAACCGCGTTTCTTTGTGTTAGGTTTTGACCGC TTTTCTTCTTTGTGCACTGTGTCACCAGGCTCCTTTTTGCCAATTTTGGACTGTTCTTTA CTTACAGGAGAAGGCTCTGCAGCTGGAGGAAGGCTTTCTTTCATGTCTGCCACTTTGTCT AGCCACACTCCAAGACACGTCAGCCTGGCATTAGTGTTTATTTCACAGAGTAAAGATGGG GGAACTTTCTTATCCTGCTTAAGCTTCCACATTTTGATGAAACCATCACTCGATGCTGAA ACAATAACATGATGCTCTGGAATTTCAAAACTGAACATGTCCTTTACCCTGTTTTCATGA GCTTTAAATTCGCAGAGGCACACTAGTGAATCACAGTCAAAAAACCTTATAACTTCTTCA TCTCCAGCCACTGCAAGGACAGACTCTGAAAGAAATTTAACAGAGGAAATTCTCTTTTCA TTTGTGATGGTGCCACTAATGGATGCAGTGTCAAGCTGATAGATGTCCATTTTATTCTGT AAGAAAACTACATACTGCTCTCCTCTTGGGGACCATTCTCTATGTGAGCATTTTGTTTTT ATTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_017906 |
| Insert Size | 1650 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_017906.2, NP_060376.2 |
| RefSeq Size | 1511 bp |
| RefSeq ORF | 1179 bp |
| Locus ID | 55003 |
| UniProt ID | Q9NWT1 |
| Domains | WD40 |
| Gene Summary | Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly (PubMed:24120868).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203074 | PAK1IP1 (Myc-DDK-tagged)-Human PAK1 interacting protein 1 (PAK1IP1) |
CNY 3,656.00 |
|
| RC203074L3 | Lenti ORF clone of Human PAK1 interacting protein 1 (PAK1IP1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203074L4 | Lenti ORF clone of Human PAK1 interacting protein 1 (PAK1IP1), mGFP tagged |
CNY 5,890.00 |
|
| RG203074 | PAK1IP1 (tGFP-tagged) - Human PAK1 interacting protein 1 (PAK1IP1) |
CNY 5,256.00 |
|
| SC320880 | PAK1IP1 (untagged)-Human PAK1 interacting protein 1 (PAK1IP1) |
CNY 3,656.00 |
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